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Stone extraction balloon-guided repeat self-expanding metal stent placement

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World Journal of Gastroenterology 2010年第24期16卷 3087-3090页

作者： Hyung Hun Kim jeong seop moon Soo Hyung Ryu Jung Hwan Lee You Sun Kim Division of Gastroenterology Department of Internal MedicineSeoul Paik Hospital Inje University College of Medicine

Self-expanding metal stent (SEMS) placement offers safe and effective palliation in patients with upper gastrointestinal obstruction due to a malignancy. Well described complications of SEMS placement include tumor growth, obstruction, and stent migration. SEMS occlusions are treated by SEMS redeployment, argon plasma coagulation application, balloon dilation, and surgical bypass. At our center, we usually place the second SEMS into the first SEMS if there is complete occlusion by the tumor. We discovered an unusual complication during SEMS redeployment. The guide-wire passed through the mesh of the first SEMS and caused the second SEMS to become entangled with the first SEMS. This led to the distortion and malfunction of the second SEMS, which worsened the gastric outlet obstruction. For lowering the risk of entanglement, we studied stone extraction balloon-guided repeat SEMS placement. This is the first report of a SEMS entangled by the mesh of the first SEMS and stone extraction balloon-guided repeat SEMS placement for lowering the risk of this complication.

关键词： Gastric outlet obstruction Self-expanding metal stent

Management of the complications of endoscopic submucosal dissection

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World Journal of Gastroenterology 2011年第31期17卷 3575-3579页

作者： Seong Hwan Kim jeong seop moon Young Hoon Youn Ki Myung Lee Sung Joon Lee Division of Gastroenterology Department of Internal MedicineEulji University Division of Gastroenterology Department of Internal MedicineInje UniversitySeoul Paik Hospital Division of Gastroenterology Department of Internal MedicineYonsei University-ang Nam Severance Hospital Division of Gastroenterology Department of Internal MedicineAjou University Hospital Division of Gastroenterology Department of Internal Medicineang-on University Hospital

Endoscopic submucosal dissection(ESD) is currently widely accepted as a standard treatment option for early gastrointestinal neoplasms in ***,ESD has technical difficulties and a longer procedure time than conventional endoscopic *** it may have a higher risk of complications than conventional endoscopic resection ***,the ESD study group of Korean Society of Gastrointestinal Endoscopy,have experienced many complications,mostly treated by endoscopic or conservative ***,we introduce and share our experiences for managementof post ESD complications and review published papers on the topic.

关键词：并发症内镜管理剥离膜下胃肠道肿瘤治疗方案公共服务

Endoscopic treatment of efferent loop syndrome with insertion of double pigtail stent

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World Journal of Gastroenterology 2013年第41期19卷 7209-7212页

作者： Woo Yong Lee jeong seop moon Department of Surgery Seoul Paik HospitalInje University College of MedicineSeoul 100-032South Korea Department of Internal Medicine Seoul Paik HospitalInje University College of MedicineSeoul 100-032South Korea

Efferent loop syndrome is a very rare postgastrectomy syndrome that can occur following Billroth-Ⅱor Rouxen-Y *** most common loop syndrome after gastric surgery is afferent loop syndrome;however,efferent loop syndrome has been reported in rare ***,we report a case of efferent loop obstruction that occurred after postoperative adhesiolysis of a small-bowel *** patient had undergone a partial gastrectomy with BillrothⅡanastomosis and gastric ulcer perforation 30 years *** efferent loop obstruction was successfully resolved by the insertion of a double pigtail *** the best of our knowledge,this is the first case in the literature describing the treatment of efferent loop obstruction.

关键词： Efferent loop syndrome Double pigtail stent Postgastrectomy syndrome

Mycobacterium ulcerans infection as a cause of chronic diarrhea in an AIDS patient: A case report

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World Journal of Gastroenterology 2008年第5期14卷 808-811页

作者： Jin-Gook Huh You-Sun Kim Jong-Sung Lee Tae-Yeob jeong Soo-Hyung Ryu Jung-Hwan Lee jeong-seop moon Yun-Kyung Kang Myung-Shup Shim Myoung-Don Oh Department of Internal Medicine Inje University College of Medicine Seoul 100-032 South Korea Department of Pathology Inje University College of Medicine Seoul 100-032 South Korea Korean Institute of Tuberculosis Seoul South Korea Department of Internal Medicine Seoul National University College of Medicine Seoul South Korea

Chronic diarrhea is one of the most frequent gastro-intestinal manifestations in acquired immunodeficiency syndrome (AIDS). Protozoa and nontuberculous mycobacteria (NTM) are opportunistic pathogens that can easily infect these patients. Among the NTM, Mycobacterium avium complex (MAC) is the most frequently observed pathogen in HIV-infected patients. However, NTMs other than MAC have not been reported as a gastrointestinal pathogen as yet. We present a case of chronic diarrhea in an AIDS patient in whom Mycobacterium ulcerans and cryptosporidium co-infection is evidenced from colonic tissue.

关键词： HIV 慢性腹泻患者症状

Long-term follow up of endoscopic resection for type 3 gastric NET

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World Journal of Gastroenterology 2013年第46期19卷 8703-8708页

作者： Yong Hwan Kwon Seong Woo Jeon Gwang Ha Kim Jin Il Kim Il-Kwun Chung Sam Ryong Jee Heung Up Kim Geom Seog Seo Gwang Ho Baik Kee Don Choi jeong seop moon Department of Internal Medicine Kyungpook National University Hospital Department of Internal Medicine Busan National University School of Medicine Department of Internal Medicine Catholic University of Korea College of Medicine Department of Internal Medicine Soonchunhyang University Department of Internal Medicine Inje University Pusan Paik Hospital Department of Internal Medicine Jeju National University School of Medicine Department of Internal Medicine Digestive Disease Research InstituteWonkwang University College of Medicine Department of Internal Medicine Hallym University College of Medicine Department of Internal Medicine University of Ulsan College of MedicineAsan Medical Center Department of Internal Medicine Inje University Seoul Paik Hospital

AIM:To clarify the short and long-term results and to prove the usefulness of endoscopic resection in type 3gastric neuroendocrine tumors(NETs).METHODS:Of the 119 type 3 gastric NETs diagnosed from January 1996 to September 2011,50 patients treated with endoscopic resection were enrolled in this *** endoscopic resection,endoscopic mucosal resection(EMR)or endoscopic submucosal dissection(ESD)was *** efficacy,complications,and follow-up results were evaluated ***:EMR was performed in 41 cases and ESD in 9 *** complete resection was performed in 40 cases(80.0%)and incomplete resection specimens were observed in 10 cases(7 vs 3 patients in the EMR vs ESD group,P=0.249).Upon analysis of the incomplete resection group,lateral or vertical margin invasion was found in six cases(14.6%)in the EMR group and in one case in the ESD group(11.1%).Lymphovascular invasions were observed in two cases(22.2%)in the ESD group and in one case(2.4%)in the EMR group(P=0.080).During the follow-up period(43.73;13-60 mo),there was no evidence of tumor recurrence in either the pathologically complete resection group or the incomplete resection *** recurrence was reported during *** addition,no mortality was reported in either the complete resection group or the incomplete resection group for the duration of the follow-up ***:Less than 2 cm sized confined submucosal layer type 3 gastric NET with no evidence of lymphovascular invasion,endoscopic treatment could be considered at initial treatment.

关键词： Stomach Neuroendocrine tumor Endo-scopic resection Treatment Carcinoid

Resveratrol prevents hypoxia-induced retinal ganglion cell death related with ErbB2

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International Journal of Ophthalmology(English edition) 2022年第3期15卷 394-400页

作者： Hyemin Seong Joo Yeon jeong Jinhyun Ryu Juyeong Park Yong‑seop Han Hyun-Kyung Cho Seong Jae Kim Jong moon Park Sang Soo Kang Seong Wook Seo Department of Ophthalmology Institute of Health SciencesCollege of MedicineGyeongsang National UniversityJinjuGyeongnam 52727Republic of Korea Department of Anatomy and Convergence Medical Science Institute of Health SciencesCollege of MedicineGyeongsang National UniversityJinjuGyeongnam 52727Republic of Korea Department of Ophthalmology Gyeongsang National University Changwon HospitalGyeongsang National UniversityCollege of MedicineChangwon 51472Republic of Korea

AIM: To confirm the changes in proteins related with hypoxia-induced retinal cell death and to assess the effects of resveratrol(Res).METHODS: The therapeutic effect of Res was verified using an ischemic/reperfusion(I/R) model in vivo and a hypoxia modelin retinal ganglion cells(RGCs) in *** of RGCs were confirmed by TUNEL *** expression was confirmed by Western blotting and *** addition, flow cytometric analysis was used to confirm the response in the cell unit to obtain more accurate ***: ErbB2 expression and apoptosis in the ganglion cell layer(GCL) increased after I/R *** of Res rescued I/R-induced ganglion cell death, downregulated apoptosis and ErbB2 protein expression in the *** subsequent in vitro models, Res affects apoptosis by regulating the phosphorylation and expression of mouse double minute 2 homolog(MDM2), along with those of *** results suggest that Res reverses GCL-specific apoptosis via downregulation of ErbB2 in ischemic ***: In light of Res favorable properties, it should be evaluated in the treatment of RGC death and related retinal disease characterized by ErbB2 and MDM2 ***, Res is appropriate therapeutic agent for treating ischemic injury-related eye diseases by targeting the expression of ErbB2 and MDM2.

关键词： ischemia/reperfusion injury hypoxia retinal ganglion cell resveratrol ErbB2

Improving hydroxyapatite coating ability on biodegradable metal through laser-induced hydrothermal coating in liquid precursor:Application in orthopedic implants

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Bioactive Materials 2023年第7期25卷 796-806页

作者： Jaeho Park Seung-Hoon Um Youngmin Seo Jaehong Lee Yu-Chan Kim Myoung-Ryul Ok Suk-Won Hwang jeong-Yun Sun Hyung-seop Han Hojeong Jeon Biomaterials Research Center Biomedical Research DivisionKorea Institute of Science and Technology(KIST)Seoul02792South Korea Department of Materials Science and Engineering Seoul National University(SNU)Seoul08826South Korea Division of Biomedical Science and Technology KIST SchoolKorea University of Science and TechnologySeoul02792South Korea KU-KIST Graduate School of Converging Science and Technology Korea UniversitySeoul02841South Korea

During the past decade,there has been extensive research toward the possibility of exploring magnesium and its alloys as biocompatible and biodegradable materials for implantable *** practical medical application,however,has been limited to specific areas owing to rapid corrosion in the initial stage and the consequent *** coatings can significantly reduce the initial corrosion of Mg alloys,and several studies have been carried out to improve the adhesion strength of the coating to the surfaces of the *** composition of hydroxyapatite(HAp)is very similar to that of bone tissue;it is one of the most commonly used coating materials for bone-related implants owing to favorable osseointegration *** this study,HAp was coated on Mg using nanosecond laser coating,combining the advantages of chemical and physical *** heat generated in the liquid precursor by the laser improved the adhesion of the coating through the precipitation and growth of HAp at the localized nanosecond laser focal area and increased the corrosion resistance and cell adhesion of *** physical,crystallographic,and chemical bondings were analyzed to explore the mechanism through which the surface adhesion between Mg and the HAp coating layer *** applicability of the coating to Mg screws used for clinical devices and improvement in its corrosion property were *** liquid environment-based laser surface coating technique offers a simple and quick process that does not require any chemical ligands,and therefore,overcomes a potential obstacle in its clinical use.

关键词： Biodegradable metal HAp coating Nanosecond laser Photothermal synthesis Soret effect(thermophoresis)

Incidence of coronary artery disease before valvular surgery in isolated severe aortic stenosis

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Chinese Medical Journal 2014年第22期127卷 3963-3969页

作者： Eun jeong Cho Sung-Ji Park Sung-A Chang Dong seop jeong Sang-Chol Lee Seung Woo Park Pyo Won Park Division of Cardiology Department of Internal MedicineCardiovascular Imaging Center Cardiac and Vascular Center Samsung Medical CenterSungkyunkwan University School of Medicine Seoul Korea Department of Thorax Surgery Samsung Medical CenterSungkyunkwan University School of Medicine Seoul Korea

Background Angina pectoris has been recognized as one of the principal symptoms of aortic valve stenosis （AS）,even in patients without significant coronary artery disease （CAD）.However,the incidence of angina pectoris and related CAD in such patients is *** is continuing debate as to whether coronary angiography is necessary before aortic valve replacement （AVR） in patients with severe *** purpose of this study was to evaluate the incidence and predictors of CAD in patients with severe AS in a Korean *** Data from all consecutive patients with severe AS undergoing AVR at a major tertiary cardiac and vascular center in Korea were entered in a prospective registry beginning in *** and echocardiographic follow-up data were recorded into the database *** CAD was defined as one or more major coronary arteries having an estimated narrowing of ≥70％ and left main coronary arteries having an estimated narrowing of ≥50％ on coronary *** excluded patients with multiple valve disease,significant aortic regurgitation,or prior CAD or valve *** Totally 574 patients with severe AS （mean age,（65.9±9.6） years） were enrolled in this *** CAD was found in 61 patients （10.6％）.Factors associated with increased likelihood of CAD were age,hypertension,diabetes mellitus,chronic renal failure,carotid disease,and aorta *** Logistic regression analysis,the independent predictor of the presence of CAD was age （P=0.011）.The incidence of CAD increased significantly at 69.2 years of *** two risk factors for cardiovascular disease was the most useful cutoff to predict whether a patient was going to have significant *** There was a low incidence of significant CAD in a population of Korean patients with severe ***,coronary angiography before AVR will be considered in patients with multiple risk factors for cardiovascular disease or in patients more than 69 years of

关键词： severe aortic stenosis coronary artery disease aortic valve replacement

Role of a wireless surface electromyography in dystonic gait in functional movement disorders: A case report

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World Journal of Clinical Cases 2020年第2期8卷 313-317页

作者： Min-Kyun Oh Hyeong seop Kim Yun jeong Jang Chang Han Lee Department of Rehabilitation Medicine Gyeongsang National University School of Medicine and Gyeongsang National University Hospital

BACKGROUND Dystonic gait(DG) is one of clinical symptoms associated with functional dystonia in the functional movement disorders(FMDs). Dystonia is often initiated or worsened by voluntary action and associated with overflow muscle activation. There is no report for DG in FMDs caused by an abnormal pattern in the ankle muscle recruitment strategy during *** SUMMARY A 52-year-old male patient presented with persistent limping gait. When we requested him to do dorsiflexion and plantar flexion of his ankle in the standing and seating positions, we didn’t see any abnormality. However, we could see the DG during the gait. There were no evidences of common peroneal neuropathy and L5 radiculopathy in the electrodiagnostic study. Magnetic resonance imaging of the lumbar spine, lower leg, and brain had no definite finding. No specific finding was seen in the neurologic examination. For further evaluation, a wireless surface electromyography(EMG) was performed. During the gait, EMG amplitude of left medial and lateral gastrocnemius(GCM) muscles was larger than right medial and lateral GCM muscles. When we analyzed EMG signals for each muscle, there were EMG bursts of double-contraction in the left medial and lateral GCM muscles, while EMG analysis of right medial and lateral GCM muscles noted regular bursts of single contraction. We could find a cause of DG in *** We report an importance of a wireless surface EMG, in which other examination didn’t reveal the cause of DG in FMDs.

关键词： Gait disorders Dystonic gait Surface electromyography Functional movement disorders Case report