检索结果-南通市图书馆

Strong association of regulatory single nucleotide polymorphisms (SNPs) of the IFITM3 gene with influenza H1N1 2009 pandemic virus infection

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2020年第6期17卷 662-664页

作者： Yong-Chan Kim Min-Ju jeong Byung-hoon jeong Korea Zoonosis Research Institute Chonbuk National UniversityIksanJeonbuk 54531Republic of Korea Department of Bioactive Material Sciences Chonbuk National UniversityJeonjuJeonbuk 54896Republic of Korea

The IFITM3 gene is classified as a member of the small interferonstimulated genes(ISGs)and plays a paramount role in defense against enveloped viruses,including influenza A viruses.1–6 Previous studies have reported that the rs12252 SNP,which is located in the open reading frame(ORF)of the IFITM3 gene,impacts the splicing procedure of protein production,which makes a truncated form of the IFITM3 protein and lowers its antiviral capacity.7–9 In addition,the rs34481144 SNP genotype affects the transcriptional regulation of the IFITM3 gene and IFITM3-neighboring genes and has a potent association with the clinical results of the H1N1 influenza 2009 pandemic in three human cohorts.10 Because several studies have reported that polymorphism of the IFITM3 gene is crucial in the host immune response,fine mapping of and extracting disease-associated SNPs from the human IFITM3 gene are important baseline studies necessary to understand how the IFITM3 protein functions in innate immunity.

关键词： IFITM3 influenza H1N1

Dielectrophoretic assembly of semiconducting single-walled carbon nanotube transistor

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2011年第A1期21卷 126-129页

作者： Se-Hun kwon Young-Keun jeong Soongeun kwon Myung-Chang KANG Hyung-Woo LEE National Core Research Center for Hybrid Materials Solution Pusan National University Department of Mechanical Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 305-701 Korea

A novel burning technique for making a semiconducting single-walled carbon nanotubes (SWNTs) transistor assembled by the dielectrophoretic force was suggested. The fabrication process consisted of two steps. First, to align and attach a bundle of SWNTs between the source and drain, the alternating (AC) voltage was applied to the electrodes. When a bundle of SWNTs was connected between two electrodes, some of metallic nanotubes and semi-conducing nanotubes existed together. The second step is to burn the metallic SWNTS by applying the voltage between two electrodes. With increasing the voltage, more current flowed through the metallic SWNTs, thus, the metallic SWNTs burnt earlier than the semiconducting one. This technique enables to obtain only semi-conducting SWNTs connection in the transistor. Through the I—V characteristic graph, the moment of metallic SWNTs burning and the characteristic of semi-conducing nanotubes were verified.

关键词：碳纳米管晶体管单壁碳纳米管束半导体燃烧技术制造过程 SWNTs 管连接特性图

Pendulation reduction on ship-mounted container crane via T-S fuzzy model

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2012年第1期19卷 163-167页

作者： JANG Jae hoon kwon Sung-Ha JEUNG Eun Tae Department of Control and Instrumentation Changwon National UniversityChangwon 641-773Korea

Ship-mounted container cranes are challenging industrial applications of nonlinear pendulum-like systems with oscillating disturbance which can cause them *** wave-induced ship motion causes the hoisted container to swing during the transfer operation,the swing motion may be dangerously large and the operation must be *** order to reduce payload pendulation of ship-mounted crane,nonlinear dynamics of ship-mounted crane is derived and a control method using T-S fuzzy model is *** results are given to illustrate the validity of the proposed design method and pendulation of ship-mounted crane is reduced significantly.

关键词：集装箱起重机 TS模糊模型船舶装载非线性动力学摆动运动非线性系统工业应用操作过程

Risk stratification for disease progression in pT3 prostate cancer after robot-assisted radical prostatectomy

在线全文

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2017年第6期19卷 700-706页

作者： jeong Hee Hong Young Suk kwon Isaac Yi Kim Section of Urologic Oncology Rutgers Cancer Institute of New Jersey Division of Urology Rutgers Robert Wood Johnson Medical School Rutgers The State University of New Jersey New Brunswick NJ 08903 USA Department of Urology Dankook University College of Medicine Cheonan 31116 South Korea.

The aim of this study is to identify optimal patients for adjuvant radiation therapy （ART） in pT3 prostate cancer. The role of ART for patients with adverse pathologic features after radical prostatectomy （RP） has been demonstrated, but over- or under-treatment remains a significant concern. Two-hundred and five patients with pT3NOMO who underwent robot-assisted RP without ART were analyzed. Multivariate Cox proportional regression analyses were used to identify predictors of biochemical recurrence （BCR） and clinical progression （CP）. The estimated 5-year BCR-free survival （BCRFS） and CP-free survival （CPFS） were 52.8% and 85.6%, respectively. Preoperative prostate-specifc antigen （PSA）：〉10 ng m1-1 （hazard ratio [HR]： 3.288-6.027; P = 0.003）, pathologic Gleason score （pGS）：〉8 （HR： 4.146; P = 0.014）, and lymphovascular invasion （LVI）（HR： 2.167; P = 0.026） were associated with BCR. Based on these factors, a risk stratification tool was developed. Patients with no risk factors （PSA 〈10 ng m1-1, pGS 6, and absent LVI） showed excellent BCRFS and CPFS at 5 years （91.9% and 100.0%, respectively）, but those with two or more risk factors （PSA ：〉10 ng ml-1, pGS ≥8, or present LVI） had poor BCRFS and CPFS （12.1% and 54.6%, respectively）. In addition, the multivariate analysis revealed that pathologic stage pT3b （HR： 5.393; P = 0.025） was the only predictor of CP. Our study demonstrated the heterogeneity of oncologic outcomes in patients with pT3 prostate cancer. The proposed risk stratification can be used to identify patients who are at risk for disease progression and may aid in identifying the best patients for ART.

关键词： prostatectomy prostate-specific antigen recurrence survival

Is thalamocortical tract injury responsible for memory impairment in a patient with putaminal hemorrhage?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2015年第2期10卷 321-322页

作者： Hyeok Gyu kwon Chul hoon Chang Sung Ho Jang Department of Physical Medicine and Rehabilitation College of Medicine Yeungnam University Department of Neurosurgery College of Medicine Yeungnam University

Prior to development of diffusion tensor imaging （DTI）, there were many difficulties in visualization and estimation of the Papez circuit in the live human brain （Papez, 1995）. Diffusion tensor tractography （DTT）, derived from DTI, allows for identification and visualization of neural tracts in the Papez circuit （Concha et al., 2005; kwon et al., 2010; Granziera et al., 2011; Jang and Yeo, 2013; Jang et al., 2014a）. In the current study, using DTT, we report on a patient who showed injured thalamocortical tract between the anterior thalamic nuclei and the cingulate gyrus following a putaminal hemorrhage.

关键词： Is thalamocortical tract injury responsible for memory impairment in a patient with putaminal hemorrhage ROI DTT

Association between scrub typhus encephalitis and diffusion tensor tractography detection of Papez circuit injury:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第13期9卷 3194-3199页

作者： Hyeok Gyu kwon jeong-Hee Yang Jee-Hyun kwon Dongseok Yang Department of Physical Therapy College of Health ScienceEulji UniversitySanseong-daero 13135Gyeonggi-doSouth Korea Department of Plastic Surgery Biomedical Research InstituteSeoul National University HospitalJongno-gu 03080SeoulSouth Korea Department of Neurology University of Ulsan College of MedicineUlsan University HospitalDong-gu 44033UlsanSouth Korea Department of Physical Medicine and Rehabilitation University of Ulsan College of MedicineUlsan University HospitalDong-gu 44033UlsanSouth Korea

BACKGROUND It is difficult to restore the cognitive functions of patients with impaired cognition caused by brain *** tensor imaging can visualize the integrity of neural tracts in the white matter(WM)*** is unclear whether encephalitis following scrub typhus damages the *** the first time,we aimed to report diffusion tensor tractography(DTT)findings in a chronic patient with cognitive impairment following scrub typhus encephalitis,which revealed injury to the Papez circuit of the *** SUMMARY A 70-year-old male patient was affected by encephalitis caused by scrub typhus that occurred 23 years *** had poor cognition and his clinical examination findings were as follows:Mini-Mental Status Examination score,14;and handgrip strength(right/left,kg),32.3/*** revealed serious injuries of the left thalamocingulate tract and right mammillothalamic tract in the Papez circuit,and a partial injury of the anterior part of the *** Using DTT,we found a relationship between cognitive impairment and the integrity of the Papez circuit following scrub typhus.

关键词： Diffusion tensor imaging Scrub typhus Encephalitis White matter Papez circuit Cognition Case report

Effects of ozonation and coagulation on effluent organic matter characteristics and ultrafiltration membrane fouling

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2014年第6期26卷 1325-1331页

作者： kwon jeong Dae-Sung Lee Do-Gun Kim Seok-Oh Ko Department of Civil Engineering Kyung Hee UniversityYongin 446-701 Korea Institute of Construction Technology KUMHO Engineering & ConstructionYongin 449-822 Korea

Effluent organic matter （EfOM） is the major cause of fouling in the low pressure membranes process for wastewater reuse. Coagulation and oxidation of biological wastewater treatment effluent have been applied for the fouling control of microfiltration membranes. However, the change in EfOM structure by pre-treatments has not been clearly identified. The changes of EfOM characteristics induced by coagulation and ozonation were investigated through size exclusion chromatography, UV/Vis spectrophotometry, fluorescence spectrophotometry and titrimetric analysis to identify the mechanisms in the reduction of ultrafiltration （UF） membrane fouling. The results indicated that reduction of flux decline by coagulation was due to modified characteristics of dissolved organic carbon （DOC） content. Total concentration of DOC was not reduced by ozonation. However, the mass fraction of the molecules with molecular weight larger than 5 kDa, fluorescence intensity, aromaticity, highly condensed chromophores, average molecular weight and soluble microbial byproducts decreased greatly after ozonation. These results indicated that EfOM was partially oxidized by ozonation to low molecular weight, highly charged compounds with abundant electron- withdrawing functional groups, which are favourable for alleviating UF membrane flux decline.

关键词： effluent organic matter fouling ultrafiltration oxidation molecular weight distribution acidity

Fuzzy logic controller design with unevenly-distributed membership function for high performance chamber cooling system

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2014年第7期21卷 2684-2692页

作者：曹健鹏 Seok-kwon jeong Young-Mi Jung Graduate School of Refrigeration and Air-conditioning Engineering Pukyong National University Department of Refrigeration and Air-conditioning Engineering Pukyong National University

Fuzzy logic controller adopting unevenly-distributed membership function was presented with the purpose of enhancing performance of the temperature control precision and robustness for the chamber cooling *** equalization and noise detection were performed to modify the evenly-distributed membership functions of error and error change rate into unevenly-distributed membership ***,the experimental results with evenly and unevenly distributed membership functions were compared under the same outside environment *** experimental results show that the steady-state error is reduced around 40% and the noise disturbance is rejected successfully even though noise range is 60% of the control precision *** control precision is improved by reducing the steady-state error and the robustness is enhanced by rejecting noise disturbance through the fuzzy logic controller with unevenly-distributed membership ***,the system energy efficiency and lifetime of electronic expansion valve(EEV) installed in chamber cooling system are improved by adopting the unevenly-distributed membership function.

关键词：模糊逻辑控制器不均匀分布冷却系统隶属度函数性能隶属函数误差变化率设计

Synthesis and Characterization of Fluoro- and Chloro-bimetallic Alkoxides as Precursors for Luminescent Metal Oxide Materials via Sol-Gel Technique

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2007年第7期25卷 998-1004页

作者： ATHAR.Taimur SEOK, Sang II kwon, jeong Oh Indian Institute of Chemical Technology Uppal Road Tarnaka Hyderabad (A.P.) 500007 India Advanced Materials Division Korea Research Institute of Chemical Technology 100 Jang-Dong Yuseong-Gu Daejon 305-343 Korea

Heterobimetallic alkoxides are broadly recognized as versatile precursors for luminescence materials, and efforts are being made to develop novel routes by applying the concept of geometrical molecular design, for their synthesis and to design a single source precursor suited to photoluminescent materials. Novel and new series of bimetallic alkoxides has been prepared by metathesis route. They exhibit a lower sensitivity towards hydrolysis and so they are easier to handle as compared to other alkoxides. All the compounds were characterized by elemental analysis, FT-IR and multinuclear NMR spectroscopies. FT-IR revealed that the molecular structure of these metal alkoxides was retained to a large extent in 4 ： 1 halogenated alcohol-benzene solution. The heteronuclear NMR spectroscopy provided useful information about chemical shifts for better understanding the likely structure based on interactions with their coordinate metals. The mass spectra show similar types of fragmentation pattern. SEM-EDS analyses showed consistency with the formulation. XRD patterns show an enhanced homogeneity at high temperature. TGA measurements show that thermal decomposition occured in steps that depended entirely on the chemical compositions and the synthesis routes. SEM observation reveals that the morphology and particle size strongly depend on synthesis routes for their precursors.

关键词： precursor chemistry fluoro- or chloro-bimetallic alkoxide geometric design luminescent material