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国际输血及血液学杂志 2006年第3期29卷 284-284页

作者： jensen ls Puho E Pedersen L 吴敏（节译）陈会友（校）田兆嵩（校）常州市中心血站江苏省常州市213003 不详

一项丹麦的实验显示,输注去白红细胞的癌症病人比输注去白膜红细胞的癌症病人术后感染并发症更少,但未进行长期研究.已知输血与癌症病人存活率有关已经有几十年时间了.而另一些观察研究则显示,输注大量去白红细胞的病人与输注去白膜红... 详细信息

一项丹麦的实验显示,输注去白红细胞的癌症病人比输注去白膜红细胞的癌症病人术后感染并发症更少,但未进行长期研究.已知输血与癌症病人存活率有关已经有几十年时间了.而另一些观察研究则显示,输注大量去白红细胞的病人与输注去白膜红细胞病人相比,其5年存活率仅稍稍高些,原因可能与手术期间进行了免疫抑制治疗有关.本文对那项丹麦实验中输注过去白膜红细胞及去白红细胞的病人采用随机分组法进行了追踪研究.

关键词：临床输血长期生存率输注术后癌症病人 5年存活率直肠去白膜红细胞去白红细胞

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OPTIMIZATION OF SHEET METAL FORMING PROCESSES USING FINITE ELEMENT SIMULATIONS

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Acta Metallurgica Sinica(English Letters) 2000年第2期13卷 531-539页

作者： K. B. Nielsen, M. R. jensen and J. Danckert Department of Production, Aalborg University, Denmark

The paper focuses on the combination of the Finite Element simulation and optimization to improve process or product quality. Three different examples to illustrate the developed genetic approach are given. In all three examples is-DYNA3D is used to simulate the process and a general aptimiza- tion sensitivity based strategy is utilized to improve the design. The included examples are: 1) stretch bending of tubes, 2) bulging of tubes, and finally 3) hydromechanical deep drawing. these examples clearly illustrate the potential of systematic optimization in the area of metal processing.

关键词： finite element method hydroforming of tubes hydromechanical deep drawing ls-DYNA3D tube bending

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The Cooperative Activities of CSLD2, CSLD3, and CSLD5 Are Required for Normal Arabidopsis Development

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Molecular Plant 2011年第6期4卷 1024-1037页

作者： Lan Yin Yves Verhertbruggen Ai Oikawa Chithra Manisseri Bernhard Knierim Lina Prak Jacob Kriiger jensen Paul Knox Manfred Auer William G.T. Willatsa and Henrik Vibe Scheller Department of Plant Biology and Biotechnology Faculty of Life Sciences University of Copenhagen DK-1871 Frederiksberg C Denmark Joint BioEnergy Institute Feedstocks Division 5885 Hollis St Emeryville CA 94608 USA Present address： Department of Arctic and Marine Biology University of Tromso 9037 Tromse Norway Physical Biosciences Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Present address： Molecular Phytopathology and Genetics University of Hamburg D-22609 Hamburg Germany f Joint BioEnergy Institute Technology Division 5885 Hollis St Emeryville CA 94608 USA Life Sciences Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Present address： Department of Plant Biology Michigan State University East Lansing MI 48824 USA Centre for Plant Sciences Faculty of Biological Sciences University of Leeds Leeds LS2 9JT UK Department of Plant and Microbial Biology University of California Berkeley CA 94720 USA Joint BioEnergy Institute Technology Division 5885 Hoilis St Emeryville CA 94608 USA

Glycosyltransferases of the Cellulose Synthase Like D （CS/D） subfamily have been reported to be involved in tip growth and stem development in Arabidopsis. The csld2 and csld3 mutants are root hair defective and the csld5 mutant has reduced stem growth. In this study, we produced double and triple knockout mutants of CSLD2, CSLD3, and CSLD5. Unlike the single mutants and the csld2/csld3 double mutant, the csld2/csld5, csld3/csld5, and csld2/csld3/csld5 mutants were dwarfed and showed severely reduced viability. This demonstrates that the cooperative activities of CSLD2, CSLD3, and CSLD5 are required for normal Arabidopsis development, and that they are involved in important processes besides the specialized role in tip growth. The mutant phenotypes indicate that CSLD2 and CSLD3 have overlapping functions with CSLD5 in early plant development, whereas the CSLD2 and CSLD3 proteins are non-redundant. To determine the biochemical function of CSLD proteins, we used transient expression in tobacco leaves. Microsomes containing heterologously expressed CSLD5 transferred mannose from GDP-mannose onto endogenous acceptors. The same activity was detected when CSLD2 and CSLD3 were coexpressed but not when they were expressed separately. With monosaccharides as exogenous acceptors, microsomal preparations from CSLD5-expressing plants mediated the transfer of mannose from GDP-mannose onto mannose. These results were supported by immunodetection studies that showed reduced levels of a mannan epitope in the cell walls of stem interfascicular fibers and xylem vessels of the csld2/csld3/csld5 mutant.

关键词： Cellulose synthase like hemicelluloses mannan glycosyltransferases polysaccharide plant development.

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