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Drought-responsive genes expressed predominantly in root tissues are enriched with homotypic cis-regulatory clusters in promoters of major cereal crops

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The Crop Journal 2017年第3期5卷 195-206页

作者： Muhammad Ramzan Khan Imran Khan Zahra Ibrar jens léon Ali Ahmed Naz Institute of Crop Science and Resource Conservation(INRES) Department of Crop Genetics and BiotechnologyRheinische Friedrich-Wilhelms University of BonnGermany National Centre for Bioinformatics(NCB) Quaid-i-Azam UniversityIslamabadPakistan National Institute for Genomics and Advanced Biotechnology(NIGAB) National Agricultural Research CentrePark RoadIslamabadPakistan

The root appears to be the most relevant organ for breeding drought stress ***, our knowledge about temporal and spatial regulation of drought-associated genes in the root remains fragmented, especially in crop plants. We performed a meta-analysis of expression divergence of essential drought-inducible genes and analyzed their association with cis-elements in model crops and major cereal crops. Our analysis of42 selected drought-inducible genes revealed that these are expressed primarily in roots,followed by shoot, leaf, and inflorescence tissues, especially in wheat. Quantitative real-time RT-PCR analysis confirmed higher expression of TaDREB2 and TaAQP7 in roots,correlated with extensive rooting and drought-stress tolerance in wheat. A promoter scan up to 2 kb upstream of the translation start site using phylogenetic footprinting revealed708 transcription factor binding sites, including drought response elements(DREs), auxin response elements(Aux REs), MYCREs/MYBREs, ABAREs, and ERD1 in 19 selected ***, these elements were organized into clusters of overlapping transcription factor binding sites known as homotypic clusters(HCTs), which modulate drought physiology in plants. Taken together, these results revealed the expression preeminence of major drought-inducible genes in the root, suggesting its crucial role in drought adaptation. The occurrence of HCTs in drought-inducible genes highlights the putative evolutionary modifications of crop plants in developing drought adaptation. We propose that these DNA motifs can be used as molecular markers for breeding drought-resilient cultivars, particularly in the cereal crops.

关键词： Gene expression Promoter DREB cis-regulatory elements Phylogeny Drought adaptation

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Eckfeld Maar:Window into an Eocene Terrestrial Habitat in Central Europe

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Acta Geologica Sinica(English Edition) 2010年第4期84卷 984-1009页

作者： Herbert lUTZ Uwe KAUlFUSS Torsten WAPPlER Werner lHNERTZ Volker WIlDE Dieter F.MERTZ jens MINGRAM jens l.FRANZEN Herbert FRANKENHUSER Martin KOZIOl Mainz Natural History Museum/State Collection for Natural History of Rhineland-Palatinate MainzGermany Department of Geology University of OtagoDunedinNew Zealand Section Palaeontology Steinmann InstituteUniversity of BonnBonnGermany Hermann-Josef-Kolleg Steinfeld Kall-SteinfeldGermany Section Palaeobotanik Senckenberg Research Institute and Natural History MuseumFrankfurt am MainGermany Institute for Geosciences Johannes Gutenberg University MainzMainzGermany Section Climate Dynamics and landscape Evolution Helmholtz Centre Potsdam GFZ German Research Centre for GeosciencesPotsdamGermany Jakobistr. Titisee-NeustadtGermany Maarmuseum Manderscheid/State Collection for Natural History of Rhineland-Palatinate ManderscheidGermany

To mark the occasion of the 175th anniversary of the Rheinische Naturforschende Gesellschaft in 2009 and of the centennial of the Mainz Natural History Museum in 2010, we present a short account of our present knowledge of the Eckfeld Maar after 20 years of continuous research. This paper does not attempt to include all of the detailed results on the geology of the Eckfeld site or its biota. To date, nearly 250 papers and books have been published since the start of our project. An up-to-date list of these publications can be found at ***.

关键词： maar lake Eocene central Europe fossil Rhenish shield

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Development of high damage threshold laser-machined apodizers and gain filters for laser applications

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High Power laser Science and Engineering 2016年第3期4卷 113-119页

作者： Patrick Rambo jens Schwarz Mark Kimmel John l.Porter Sandia National laboratories

We have developed high damage threshold filters to modify the spatial profile of a high energy laser beam. The filters are formed by laser ablation of a transmissive window. The ablation sites constitute scattering centers which can be filtered in a subsequent spatial filter. By creating the filters in dielectric materials, we see an increased laser-induced damage threshold from previous filters created using ‘metal on glass' lithography.

关键词： apodization laser beam shaping laser micro-machining spatial filtering

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Systematic review of centrifugal valving based on digital twin modeling towards highly integrated lab-on-a-disc systems

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Microsystems & Nanoengineering 2021年第6期7卷 45-70页

作者： jens Ducrée School of Physical Sciences Dublin City UniversityDublinIreland

Current,application-driven trends towards larger-scale integration(lSI)of microfluidic systems for comprehensive assay automation and multiplexing pose significant technological and economical challenges to *** virtue of their intrinsic capability for powerful sample preparation,centrifugal systems have attracted significant interest in academia and business since the early *** review models common,rotationally controlled valving schemes at the heart of such“lab-on-a-Disc”(loaD)platforms to predict critical spin rates and reliability of flow control which mainly depend on geometries,location and liquid volumes to be processed,and their experimental *** absence of larger-scale manufacturing facilities during product development,the method presented here facilitates efficient simulation tools for virtual prototyping and characterization and algorithmic design optimization according to key performance *** virtual in silico approach thus significantly accelerates,de-risks and lowers costs along the critical advancement from idea,layout,fluidic testing,bioanalytical validation,and scale-up to commercial mass manufacture.

关键词： centrifugal advancement modeling

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Impact of the spindle number on the material transport and mixing during planetary roller melt granulation Author links open overlay panel

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Particuology 2024年第8期91卷 260-267页

作者： Tom lang jens Bartsch laboratory of Solids Process Engineering Department of Biochemical and Chemical EngineeringTU Dortmund University44227DortmundGermany

In comparison to the established twin-screw machines,the application of a planetary roller granulator for continuous operation of melt granulation is a promising alternative based on the unique process *** initial study focused on the material transport during processing as a key driver for the overall ***,the impact of direct process parameters on the residence time distribution was the main *** investigations are complemented in this study by considering the free processing volume,which is defined by the number of planetary spindles applied within a *** impact on the processing conditions is evaluated with respect to the process setting in terms of feed rate and rotation *** results highlight the potential of altering the underlying transport function in planetary roller melt granulation(PRMG)via the investigated direct process and equipment *** impact of the feed rate is lower in comparison,while a higher rotation speed as well as a higher free processing volume promote material ***,a normalization of the determined residence time distribution(RTD)model data was feasible with respect to the process settings and the number of applied planetary spindles in the processing *** demonstrates the key role of the free processing volume in the fundamental mechanisms of material transport and mixing during PRMG.

关键词： Continuous manufacturing Melt granulation Planetaryroller granulator Quality-by-Design Residence time Material mixing

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Nash and Stackelberg Differential Games

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Chinese Annals of Mathematics,Series B 2012年第3期33卷 317-332页

作者： Alain BENSOUSSAN jens FREHSE jens VOGElGESANG International Center for Decision and Risk Analysis School of ManagementUniversity of Texas-Dallas800 West Camptell RdSM30RichardsonTX 75050-3021USA Faculty of Business The Hong Kong Polytechnic University Department of Mathematics Institute of Applied MathematicsUniversity of BonnGermany PACM Princeton UniversityUSA HCM University of BonnGermany

A large class of stochastic differential games for several players is considered in this *** class includes Nash differential games as well as Stackelberg differential games.A mix is *** existence of feedback strategies under general conditions is *** limitations concern the functionals in which the state and the controls appear *** is also true for the state *** controls appear in a quadratic form for the payoff and linearly in the state *** most serious restriction is the dimension of the state equation,which cannot exceed *** reason comes from PDE(partial differential equations) techniques used in studying the system of Bellman equations obtained by Dynamic Programming *** the authors' previous work in 2002,there is not such a restriction,but there are serious restrictions on the structure of the Hamiltonians,which are violated in the applications dealt with in this article.

关键词： Stochastic games Bellman equation Nonlinear elliptic and parabolicequations Stochastic differential games Hamiltonians

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Development of fungal cell factories for the production of secondary metabolites:linking genomics and metabolism

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Synthetic and Systems Biotechnology 2017年第1期2卷 5-12页

作者： jens Christian Nielsen jens Nielsen Chalmers University of Technology Kemivagen 10Sweden

The genomic era has revolutionized research on secondary metabolites and bioinformatics methods have in recent years revived the antibiotic discovery process after decades with only few new active molecules being *** computational tools are driven by genomics and metabolomics analysis,and enables rapid identification of novel secondary *** translate this increased discovery rate into industrial exploitation,it is necessary to integrate secondary metabolite pathways in the metabolic engineering *** this review,we will describe the novel advances in discovery of secondary metabolites produced by filamentous fungi,highlight the utilization of genome-scale metabolic models(GEMs)in the design of fungal cell factories for the production of secondary metabolites and review strategies for optimizing secondary metabolite production through the construction of high yielding platform cell factories.

关键词： Secondary metabolism Fungi Biosynthetic gene clusters Genome mining Metabolic modeling Cell factories

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Pressure drop of structured packing in pilot column and comparison to common correlations

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Chinese Journal of Chemical Engineering 2023年第12期64卷 281-291页

作者： Emil Madsen Randi Neerup Arne Gladis jens K.Jørsboe Nicolas von Solms Philip l.Fosbøl Center for Energy Resources Engineering(CERE) Department of Chemical and Biochemical EngineeringTechnical University of Denmark(DTU)Søltofts Plads 2292800 Kgs.LyngbyDenmark

Packed columns are widely used in the chemical industry such as absorption,stripping,distillation,and extraction in the production of *** chemicals,and *** loss and pressure drop correlations are of special interest when it comes to the hydrodynamic properties of a *** pressure loss across the column is of interest in the design phase when the size of the blower to drive the gas stream through the column has to be *** loading point and flooding point are also influenced by the pressure loss and the area of operation is determined from these *** work examines four different correlations on pressure *** correlations are(i)Ergun’s equation(1952),(ii)an improved version of Ergun’s equation by Stichlmair,Bravo,and Fair(1989),(iii)an equation developed by Billet and Schultes(1999),and(iv)an equation by Rocha,Bravo,and Fair(1993).The complexity of the correlations is increasing in the mentioned order,Ergun’s equation being the simplest *** study investigates if the more complicated correlations give better predictions to pressure drop in packed *** is determined by comparing the correlations to experimental data for pressure drop in a packed column with 8.2 m of structured packing using water as the liquid and atmospheric air as the *** experiments were carried out for determining the pressure drop in the column with liquid flows varying from 0 to 500 kg·h^(-1).At constant liquid flow,the gas flow was varied from approximately 10 to 70 kg·h^(-1).The pressure drop across the non-wetted column was best described by the correlation by Rocha et *** the pressure drop for liquid flows from 100 to 500 kg·h^(-1)was,in general,best described by Stichlmair’s *** an irrigated column,the highest deviation was a predicted pressure drop 69.6%lower than *** best prediction was 0.1%higher than the *** study shows,surprisingly,that for a system of water and atmospheric air,complica

关键词： Pressure drop correlations Packed columns Structured packing Fluid dynamics

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Automatic route planning for GPS art generation

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Computational Visual Media 2019年第3期5卷 303-310页

作者： Andre Waschk jens Krüger University of Duisburg-Essen

In this paper, we present a novel approach to automated route generation of global positioning system(GPS) artwork. The term GPS artwork describes the generation of drawings by leaving virtual traces on digital maps. Until now, the creation of these images has required a manual planning phase in which an artist designs the route by hand. Once the route for this artwork has been planned, GPS devices have been used to track the movement. Using our solution, the lengthy planning phase can be significantly shortened,thereby opening art creation to a broader public.

关键词： GPS art walking routing shape detection navigation

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Chaotic ray dynamics enables photonics with broadband light

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Science China(Physics,Mechanics & Astronomy) 2018年第1期61卷 78-79页

作者： Hailin Wang jens Nockel Department of Physics University of Oregon Eugene OR 97403 USA

Propagation of sound waves through reflections along a curved surface was first theoretically analyzed by lord Rayleigh to explain the whispering gallery waves in St. Paul＇s Cathedral in london. Similar whispering gallery sound waves are now a popular tourist attraction at the Echo Wall of the Temple of Heaven in Beijing. Whispering gallery phenomena also exist for light waves in dielectric spheres, disks, or toroids where total internal reflection allows the light to circulate with little attenuation and interfere with itself to form optical resonances or modes. These ＂whisper- ing gallery modes＂ have found applications ranging from photonics, quantum physics, biosensing, to optical clocks [1,2].

关键词： Chaotic ray dynamics enables photonics broadband light

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