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Infectious Diseases of Poverty 2021年第3期10卷 124-124页

作者： Caitlin sheehy Heather Lawson Emmanuel H.Andriamasy Hannah J.Russell Alice Reid Gina U.Raderalazasoa Graham Dodge Robbie Kornitschky James M.stJPenney Tahiry N.Ranaivoson Antsa Andria niaina jenny s.emmanoela Amaya L.Bustinduy JRussell stothard Louis Andrianjaka stephen A.spencer The University of Man Chester Medical school University of Man ChesterManchester M139NTUK 不详

school-aged children(sAC)have a considerable burden of intestinal schistosomiasis in Madagascar yet its burden in pre-school aged children(PsAC)is currently *** assess the at-risk status of PsAC,we undertook a pilot epidemiological survey in June 2019 examining children(n=89),aged 2-4-years of balanced gender,in six remote villages in Marolambo District,*** included use of urine-circulating cathodic antigen(CCA)dipsticks and coproscopy of stool with duplicate Kato-Katz(K-K)thick smears.

关键词： schistosoma mansoni soil-transmitted helminthiasis Paediatric Praziquantel Mass drug administration

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

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Neural Regeneration Research 2025年第1期20卷 291-304页

作者： simeon C.Daeschler Katelyn J.W.so Konstantin Feinberg Marina Manoraj jenny Cheung Jennifer Zhang Kaveh Mirmoeini JPaul santerre Tessa Gordon Gregory HBorschel sickKids Research Institute Neuroscience and Mental Health ProgramTorontoONCanada Institute of Biomaterials and Biomedical Engineering University of TorontoTorontoONCanada Indiana University school of Medicine IndianapolisINUSA Division of Plastic and Reconstructive surgery the Hospital for Sick ChildrenTorontoONCanada Translational Biology and Engineering Program Ted Rogers Centre for Heart ResearchInstitute of Biomedical EngineeringFaculty of DentistryUniversity of TorontoTorontoONCanada

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong ***,there are no FDA-approved therapies available to promote nerve *** accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve *** authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug *** is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 *** and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible *** released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic *** its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

关键词： biodegradable local drug delivery nerve injury nerve regeneration nerve wrap tacrolimus

A comprehensive review on bitter gourd (Momordica charantia L.) as a gold mine of functional bioactive components for therapeutic foods

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Food Production, Processing and Nutrition 2022年第1期4卷 107-120页

作者： K.s.Gayathry jenny Ann John Faculty of Ocean science and Technology Kerala(Department of Food Science and Technology)Kerala University of Fisheries and Ocean Studies(KUFOS)Panangad P.O.KochiKerala682506India

Bitter gourd is a tropical wine grown mainly in India, China and south East Asia. The plant is cultivated mainly for its fruit part which is edible. Bitter gourd is unaccepted widely due to its bitter taste. Nevertheless, the fruit is a source of several key nutrients. The plant, as a whole contains, more than 60 phyto-medicines that are active against more than 30 diseases, including cancer and diabetes. Currently, the incorporation of the bioactive compounds isolated from bitter gourd into functional foods and beverages finds a new horizon. Nanoencapsulation and novel green extraction methods can be employed to improve the yield and quality of extracted compounds and their stability while incorporation into food products. The present review is an attempt to throw light to nutritional aspects, various bioactive compounds present and important nutraceutical properties of the bitter gourd plant in detail.

关键词： Bitter gourd Bioactive Nutraceutical Extraction Encapsulation

Calciomics:prediction and analysis of EF-hand calcium binding proteins by protein engineering

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science China Chemistry 2010年第1期53卷 52-60页

作者： YANG jenny Jie Department of Chemistry Georgia State University

Ca2+ plays a pivotal role in the physiology and biochemistry of prokaryotic and mammalian *** also utilize the universal Ca2+ signal to create a specific cellular environment to achieve coexistence with the host,and to *** this paper we first describe our development of a grafting approach to understand site-specific Ca2+ binding properties of EF-hand proteins with a helix-loop-helix Ca2+ binding motif,then summarize our prediction and identification of EF-hand Ca2+ binding sites on a genome-wide scale in bacteria and virus,and next report the application of the grafting approach to probe the metal binding capability of predicted EF-hand motifs within the streptococcal hemoprotein receptor(shr) of streptococcus pyrogenes and the nonstructural protein 1(nsP1) of sindbis *** methods such as the grafting approach are developed in conjunction with prediction algorithms we are better able to probe continuous Ca2+-binding sites that have been previously underrepresented due to the limitation of conventional methodology.

关键词： Ca2+ EF-hand calcium binding pockets protein grafting approach streptococcus pyrogenes sindbis virus

Perfluoroalkyl acid transformation and mitigation by nNiFe-activated carbon nanocomposites in steady-state flow column studies

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Journal of Environmental sciences 2023年第5期127卷 678-687页

作者： Mahsa Modiri-Gharehveran Younjeong Choi jenny E.Zenobio Linda s.Lee Department of Agronomy Purdue UniversityWest LafayetteIN 47907USA Interdisciplinary Ecological sciences&Engineering Purdue UniversityWest LafayetteIN 47907USA

The ongoing contamination of groundwater with per-and polyfluoroalkyl substances(PFAs)has resulted in a global and rapidly growing interest in PFAs groundwater *** technologies that lead to PFAs destruction are often limited by not addressing all PFAs,being energy-intensive or not being suited for in-situ *** developed nNiFeactivated carbon(AC)nanocomposites and demonstrated varying degrees of PFAs reduction and fluoride generation with these nanocomposites in batch reactors for several *** we explore nNiFe-AC’s effectiveness to transform perfluoroalkyl acid acids(PFAAs)under steady-state flow(0.0044 to 0.15 mL/min)in nNiFe-AC:sand packed *** experiments included,two perfluorooctane sulfonate(PFOs)in deionized water and two PFAA mixtures in deionized water or bicarbonate buffer containing five perfluoroalkyl carboxylates(PFCAs,C5-C9)and three perfluoroalkyl sulfonates(PFsAs,C4,C6 and C8)at temperatures of 50 or 60℃ were *** transformation was similar in PFOs-only and PFAA mixture column ***,%PFAA transformation under flow conditions exceeded what we observed previously in batch reactors with up to 53%transformation of a PFAA mixture with∼8%*** chain PFAs dominated the PFAAs transformed and a bicarbonate matrix appeared to reduce overall *** breakthrough was slower than predicted from only sorption due to transformation;some longer chain PFAs like PFOs did not ***,nNiFe-AC technology with both in-situ and ex-situ potential application was shown to be a plausible part of a treatment train needed to address the ongoing challenge for cleaning up PFAs-contaminated waters.

关键词： PFAAs PFAs Zero valent iron Nanoparticles Remediation Groundwater

Laboratory assessment of Alaska aggregates using Micro-Deval test

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Frontiers of structural and Civil Engineering 2017年第1期11卷 27-34页

作者： jenny LIU sheng ZHAO Anthony MULLIN Department of Civil and Environmental Engineering University of Alaska Fairbanks Fairbanks AK 99775-5900 USA Center for Environmentally sustainable Transportation in Cold Climates Institute of Northern Engineering University of AlaskaFairbanks Fairbanks AK 99775-5900 USA

Aggregates suitable for use in asphalt concrete （AC） pavement construction must meet durability criteria. Thus, it is critical to select appropriate tests to properly characterize aggregate durability. In Alaska, durability tests currently being used for aggregates in AC pavement include Los Angeles （LA） abrasion test, sulfate soundness test and Washington degradation test. However, there have long been concerns arising over Washington degradation test used as an acceptance tool, motivating pavement practitioners to seek more suitable alternatives. This paper presents a study to investigate the feasibility of using Micro-Deval test, commonly used in other states, to evaluate the durability of Alaskan aggregates in AC pavement as well as its potential to replace Washington degradation test. Micro-Deval test, Washington degradation test and other tests currently specified in Alaska were conducted on aggregates from 16 batches representing statewide sources. Based on the testing results, it is found that using Micro-Deval test for durability assessment of Alaska aggregates was feasible and reproducible, and a high potential was revealed to use Micro-Deval test to replace Washington degradation test in Alaska. It is recommended that Micro-Deval test be considered as an additional test for a certain period, but in the long run should be used along with current LA abrasion and sulfate soundness tests to provide a more desirable durability assessment of Alaska aggregates used in AC pavement.

关键词： aggregate durability Washington degradation test Micro-Deval test

study of methods for endpoint aware inspection in a next generation firewall

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Cybersecurity 2022年第4期5卷 56-70页

作者： jenny Heino Antti Hakkala seppo Virtanen Department of Computing University of TurkuTurkuFinland Forcepoint LLC HelsinkiFinland

Given the global increase in remote work with the COVID-19 pandemic and deperimeterization due to cloud deployment of next generation frewalls,the concept of a next generation firewall is at a breaking *** is becoming more dificult to define the barrier between the good and the *** provide the best security for an endpoint with minimal false positives or false negatives it is often necessary to identify the communicating endpoint application.n this study,we present an analysis of key research and methods for providing endpoint aware protection in the context of a next generation frewall We examine both academic research as well as state-of-the-art of the existing next generation firewall *** divide endpoint application identification into passive and active *** passive endpoint application identification,we study several traffc fingerprinting methods for different *** active methods we consider active scanning,endpoint metadata analysis and content injection and reference existing *** conclude that there are several open areas for future research,and that none of the considered methods is a silver bullet solution for endpoint aware inspection in the context of a next generation *** our best knowledge,this is the first study to examine current research and existing implementations of endpoint aware inspection.

关键词： Network traffc Endpoint identification NGFW Endpoint aware inspection

NUDGING OCCUPANT BEHAVIOR-CULTIVATING POsITIVE AssOCIATIONs BETWEEN COMFORT,HEALTH,AND BUILDING EFFICIENCY ACTIONs WITH THE DENVER HOUsING AUTHORITY

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Journal of Green Building 2015年第1期10卷 68-84页

作者： jenny Carney YR&G Sustainabil Consulting Educ & Anal New York NY 10002 USA

*** CTION Established in 1938,the Housing Authority of the City and County of Denver(DHA)is one of the nation’s most successful housing authorities,providing a variety of livable affordable housing options throughout Denver ***’s mission is to serve the residents of Denver by developing,owning,and operating safe,decent,and affordable housing in a manner that promotes thriving *** manages,owns,and operates a large portfolio of residential,warehouse,office and commercial properties through the City and County of Denver,*** of DHA’s strategic goals is to develop and operate sustainable energy efficiency properties through the Denver *** continues to develop and rehab buildings that meet the UsGBC rating system and Green Enterprise Communities standards,include the development of LEED Platinum *** addition to developing and maintaining energy efficient properties,DHA is also focused on engaging with residents to encourage responsible choices around energy *** believes there is significant opportunity for energy and water savings through focusing on the human dimension of energy ***&G has been working with DHA since 2010 supporting sustainable design initiatives for their new construction *** 2014,YR&G began working with DHA to design,implement,and perform measurement and verification for a resident education and engagement program focused on energy and water conservation *** intent is to produce a replicable program that can be implemented across DHA properties.

关键词： Multi-family residential energy efficiency water efficiency affordable housing occupant engagement behavior community-based social marketing(CBsM) health comfort

Treatment options of inflammatory appendiceal masses in adults

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World Journal of Gastroenterology 2013年第25期19卷 3942-3950页

作者： jenny Tannoury Bassam Abboud Department of General surgery Hotel Dieu de France Hospital Faculty of Medicine SaintJoseph University

At present, the treatment of choice for uncomplicated acute appendicitis in adults continues to be surgical. The inflammation in acute appendicitis may sometimes be enclosed by the patient's own defense mechanisms, by the formation of an inflammatory phlegmon or a circumscribed abscess. The management of these patients is controversial. Immediate appendectomy may be technically demanding. The exploration often ends up in an ileocecal resection or a right-sided hemicolectomy. Recently, the conditions for conservative management of these patients have changed due to the development of computed tomography and ultrasound, which has improved the diagnosis of enclosed inflammation and made drainage of intra-abdominal abscesses easier. New efficient antibiotics have also given new opportunities for nonsurgical treatment of complicated appendicitis. The traditional management of these patients is nonsurgical treatment followed by interval appendectomy to prevent recurrence. The need for interval appendectomy after successful nonsurgical treatment has recently been questioned because the risk of recurrence is relatively small. After successful nonsurgical treatment of an appendiceal mass, the true diagnosis is uncertain in some cases and an underlying diagnosis of cancer or Crohn's disease may be delayed. This report aims at reviewing the treatment options of patients with enclosed appendiceal inflammation, with emphasis on the success rate of nonsurgical treatment, the need for drainage of abscesses, the risk of undetected serious disease, and the need for interval appendectomy to prevent recurrence.

关键词： Appendicitis Phlegmon Abscess Computed tomography Antibiotics Percutaneous drainage surgery

A filtering-based bridge weigh-in-motion system on a continuous multi-girder bridge considering the influence lines of different lanes

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Frontiers of structural and Civil Engineering 2020年第5期14卷 1232-1246页

作者： Hanli WU Hua ZHAO jenny LIU Zhentao HU Key Laboratory for Wind and Bridge Engineering of Hunan Province College of Civil EngineeringHunan UniversityChangsha 410082China Department of Civil Architectural and Environmental EngineeringMissouri University of Science and TechnologyRollaMO 65409USA Qingyuan Traffic and Transportation Bureau Qingyuan 511500China

A real-time vehicle monitoring is crucial for effective bridge maintenance and traffic management because overloaded vehicles can cause damage to bridges,and in some extreme cases,it will directly lead to a bridge *** weigh-in-motion(BWIM)system as a high performance and cost-effective technology has been extensively used to monitor vehicle speed and weight on ***,the dynamic effect and data noise may have an adverse impact on the bridge responses during and immediately following the vehicles pass the *** fast Fourier transform(FFT)method,which can significantly purify the collected structural responses(dynamic strains)received from sensors or transducers,was used in axle counting,detection,and axle weighing technology in this *** further improve the accuracy of the BWIM system,the field-calibrated influence lines(ILs)of a continuous multi-girder bridge were regarded as a reference to identify the vehicle weight based on the modified Moses algorithm and the least squares *** situ experimental results indicated that the signals treated with FFT filter were far better than the original ones,the efficiency and the accuracy of axle detection were significantly improved by introducing the FFT method to the BWIM ***,the lateral load distribution effect on bridges should be considered by using the calculated average ILs of the specific lane individually for vehicle weight calculation of this lane.

关键词： bridge weigh-in-motion continuous bridge fast Fourier transform influence line axle weight calculation