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Fungal Diversity 2014年第1期64卷 181-203页

作者： Eric Kuhnert Jacques Fournier Derek Peršoh Janet jennifer Divinagracia luangsa-ard Marc Stadler Department of Microbial Drugs Helmholtz-Zentrum für Infektionsforschung GmbHInhoffenstrasse 738124 BraunschweigGermany Las Muros 09420 RimontFrance Department of Mycology University of BayreuthUniversitätsstraße 3095540 BayreuthGermany National Center for Genetic Engineering and Biotechnology(BIOTEC) 113 Thailand Science ParkPhaholyothin RoadKlong LuangPathumthani 12120Thailand

Three new species of Hypoxylon(Xylariaceae)collected from Martinique in the French Caribbean are recognised by new combinations of morphological *** status as undescribed taxa was supported by secondary metabolite profiling based on High performance liquid chromatography with diode array and mass spectrometric detection(HPLC/DAD-MS)as well as by comparison of ITS and partialß-tubulin DNA sequences with related *** the course of this study,the teleomorph of Nodulisporium griseobrunneum was found,and this species could be transferred to ***,several names in Hypoxylon are epitypified by selecting recently collected specimens from the same geographic areas as the holotypes came *** the fact that our study used the hitherto most extensive taxon sampling,the phylogenetic analyses inferred from ITS andß-tubulin sequences remain contradictory to each other,and neither genealogy was found fully in agreement with phenotype-derived *** conclude that the right gene(or multi-gene genealogies)to reflect the phylogeny and evolution of Hypoxylon still remains to be *** the time being,we recommend that the application of polyphasic taxonomic concepts should be continued in taxonomic studies of Hypoxylon.

关键词： Biodiversity Chemotaxonomy Epitypification Phylogeny Systematics Xylariaceae

Beauvericin production by the Lepidoptera pathogenic fungus Isaria tenuipes: Analysis of natural specimens, synnemata from cultivation, and mycelia from liquid-media fermentation

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Natural Products and Bioprospecting 2011年第3期1卷 112-115页

作者： Sumalee SUPOTHINA Urarat SRISANOH Sutichai NITHITHANASILP Kanoksri TASANATHAI J.jennifer luangsa-ard Chun-Ru LI Masahiko ISAKA National Center for Genetic Engineering and Biotechnology(BIOTEC) 113 Thailand Science ParkPhaholyothin RoadKlong LuangPathumthani 12120Thailand Anhui Provincial Key Laboratory for Microbial Control Anhui Agricultural UniversityHefei 230036AnhuiChina

Beauvericin was analyzed in three forms of the Lepidoptra pathogenic fungus Isaria tenuipes(4 isolates):(a)natural specimen,(b)cultivated synnemata on rice media,and(c)mycelia from fermentation in liquid *** was detected in very low amounts in all tested natural *** on rice contained much higher concentrations of beauvericin than the corresponding natural materials,although the concentrations were lower than mycelia from liquid *** results casted a caution that beauvericin concentration should be carefully checked,as a possible toxic constituent,upon mass production of a selected strain of Isaria tenuipes for health food purposes.

关键词： beauvericin Isaria tenuipes chemotaxonomy toxin

Working toward an integrated plasticity/network framework for repetitive transcranial magnetic stimulation to inform tailored treatments

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Neural Regeneration Research 2024年第7期19卷 1423-1424页

作者： Jessica Moretti jennifer Rodger Experimental and Regenerative Neurosciences School of Biological SciencesUniversity of Western AustraliaCrawleyWAAustralia Brain Plasticity Lab Perron Institute for Neurological and Translational ScienceNedlandsWAAustralia

Non-invasive brain stimulation techniques(NIBS),including repetitive transcranial magnetic stimulation(rTMS) and transcranial electric stim ulation(tES),are increasingly being adopted clinically for treatment of neuropsychiatric and neurological disorders,albeit with varying *** rationale behind the use of NIBS has historically been that stim ulation techniques modulate neuronal activity in the targeted region and consequently induce plasticity which can lead to therapeutic outcomes.

关键词： stimulation transcranial treatment

Implications of regional identity for neural stem and progenitor cell transplantation in the injured or diseased nervous system

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Neural Regeneration Research 2024年第4期19卷 715-716页

作者： Prakruthi Amar Kumar jennifer N.Dulin Department of Biology Texas A&M UniversityCollege Station Texas A&M Institute for Neuroscience Texas A&M UniversityCollege Station

Neural stem and progenitor cell(NSPC)transpla ntation has emerged as a promising therapeutic strategy for replacing lost neuronal populations and repairing damaged neural circuits following nervous system injury and disease.A great deal of experimental work has investigated the biology of NSPC grafting in preclinical animal models;more recently.

关键词： neural system injured

Classifying moisture sources associated with snowfall in the mountains of Lesotho

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Journal of Mountain Science 2024年第6期21卷 1941-1953页

作者： Alexi M.MARINAKI jennifer M.FITCHETT School of Geography Archaeology and Environmental StudiesUniversity of the WitwatersrandPrivate Bag X3Wits 2050South Africa

An average of eight snowfall events occur each year in the eastern Lesotho *** snowfall events are typically associated with cut-off low(CoLs)systems and mid-latitude ***,the moisture sources of the snowfall are unclassified and *** Hybrid Single-Particle Lagrangian Integrated Trajectory(HYSPLIT)model,an air mass back trajectory model,has been used to evaluate moisture source waters locally in southern Africa and internationally in China and *** study uses HYSPLIT to determine the source moisture of snow in Lesotho.A list of all 82 snowfall events in Lesotho spanning 2017 to 2022 was compiled using the Snow Report SA Instagram page,including the date and location of snowfall.A 72-hour back trajectory for each snowfall event was initiated for both Afriski and the whole of *** amounts to models of moisture source trajectories for 28 and 82 snowfall days,*** air mass pathways are classified according to their frequency per snowfall event,per month in the snow season,per year and for the full *** this,associated moisture source regions and dominant air mass trajectories were *** study reports that the air mass trajectories associated with Afriski and Lesotho as a whole are very *** most common pathway of air mass trajectories transporting snow-bearing moisture to Lesotho was an inland trajectory from the northern regions of southern *** pathway makes up 16.6%of all trajectories reported and is associated with the Angola Low,the Congo Air Boundary and the *** High Pressure.

关键词： Eastern Lesotho Highlands Afriski Snow Cut-off Lows HYSPLIT Synoptic Climatology

Increasing polymer scission rate by tying an overhand knot

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Science China Chemistry 2024年第11期67卷 3498-3499页

作者： Yuheng Hu jennifer T.Ou Jim Y.Huang Yuanning Feng Department of Chemistry and Biochemistry The University of Oklahoma

Similar to the phenomenon of knotted ropes in life, knotted climbing ropes will reduce their strength due to knots. Although computer simulations [1], theoretical speculation[2,3], and intuition [3] suggest that similar processes may occur at the nanoscale, this hypothesis has not been experimentally proven before. With the increasing maturity of molecular recognition and self-assembly, a research communication by Leigh et al. [4] published in Nature Chemistry introduced a molecular overhand knot into a polymer to study its effect on the scission rate of the polymer chain under tension.

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Exercise and exerkine upregulation:Brain-derived neurotrophic factor as a potential non-pharmacological therapeutic strategy for Parkinson’s disease

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BIOCELL 2024年第5期48卷 693-706页

作者： VIRAAJ VISHNU PRASAD jennifer SALLY SAMSON VENKATACHALAM DEEPA PARVATHI Department of Biomedical Sciences Sri Ramachandra Institute of Higher Education and ResearchChennai600116India

Physical activity and exercise have several beneficial roles in enhancing both physiological and psychological well-being of an *** addition to aiding the regulation of aerobic and anaerobic metabolism,exercise can stimulate the synthesis of exerkine hormones in the circulatory *** several exerkines that have been investigated for their therapeutic potential,Brain-derived neurotrophic factor(BDNF)is considered the most promising candidate,especially in the management of neurodegenerative *** to the ability of physical activity to enhance BDNF synthesis,several experimental studies conducted so far have validated this hypothesis and produced satisfactory results at the pre-clinical *** review highlights some of the recent animal model studies that have evaluated the efficiency of exercise in enhancing BDNF synthesis and promoting neuroprotective ***,this review focuses on understanding the therapeutic benefits of exercise-induced exerkine synthesis as a non-pharmacological strategy in Parkinson’s disease(PD).Regarding physical activity and exerkine induction,the neuromuscular electrical stimulation(NMES)strategy could be considered as an alternate treatment modality for patients affected with PD.

关键词： Exercise therapy Dopaminergic neurons Parkinson’s disease Brain-derived neurotrophic factor Electrical stimulation

A predictive model for ethylene-mediated auxin and cytokinin patterning in the Arabidopsis root

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Plant Communications 2024年第7期5卷 120-137页

作者： Simon Moore George Jervis jennifer F.Topping Chunli Chen Junli Liu Keith Lindsey Department of Biosciences Durham UniversitySouth RoadDurham DH13LEUK Hubei Hongshan Laboratory College of Life Science and TechnologyHuazhong Agricultural UniversityWuhan 430070China National Key Laboratory for Germplasm Innovation and Utilization for Fruit and Vegetable Horticultural Crops Huazhong Agricultural UniversityWuhanHubei 430070China

The interaction between auxin and cytokinin is important in many aspects of plant *** measurements of both auxin and cytokinin concentration and reporter gene expression clearly show the coexistence of auxin and cytokinin concentration patterning in Arabidopsis root ***,in the context of crosstalk among auxin,cytokinin,and ethylene,little is known about how auxin and cytokinin concentration patterns simultaneously emerge and how they regulate each other in the Arabidopsis *** work utilizes a wide range of experimental observations to propose a mechanism for simultaneous patterning of auxin and cytokinin *** addition to revealing the regulatory relationships between auxin and cytokinin,this mechanism shows that ethylene signaling is an important factor in achieving simultaneous auxin and cytokinin patterning,while also predicting other experimental *** the mechanism with a realistic in silico root model reproduces experimental observations of both auxin and cytokinin *** made by the mechanism can be compared with a variety of experimental observations,including those obtained by our group and other independent experiments reported by other *** of these predictions include patterning of auxin biosynthesis rate,changes in PIN1 and PIN2 patterns in pin3,4,7 mutants,changes in cytokinin patterning in the pls mutant,PLS patterning,and various trends in different *** research reveals a plausible mechanism for simultaneous patterning of auxin and cytokinin concentrations in Arabidopsis root development and suggests a key role for ethylene pattern integration.

关键词： Arabidopsis root auxin patterning cytokinin patterning ethylene signaling in silico digital root spatiotemporal modeling

Germline Gene-Editing Creates Enhanced Livestock-Technical and Especially Ethical Issues Challenge Its Use in Humans

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Engineering 2024年第2期33卷 3-5页

作者： jennifer Welsh Senior Technology Writer

Using clustered regularly interspaced short palindromic repeats(CRISPR)-based molecular tools,scientists are engineering-as they are also doing with plants.-animals with advantageous traits,like disease resistance and improved food *** these innovative techniques could one day be applied in humans,technical hurdles and ethical concerns likely place this possibility far in the future,The enhancements rely on germline gene editing,which alters the genes in a way that passes the changes on to *** m-line gene editing differs from the somatic cell gene editing used in the highly promising new treatment recently approved for the human disease sickle cell anemia.

关键词： likely Create editing

The Faces of Fungi database:fungal names linked with morphology,phylogeny and human impacts

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Fungal Diversity 2015年第5期74卷 3-18页

作者： Subashini C.Jayasiri Kevin D.Hyde Hiran A.Ariyawansa Jayarama Bhat Bart Buyck Lei Cai Yu-Cheng Dai Kamel A.Abd-Elsalam Damien Ertz Iman Hidayat Rajesh Jeewon E.B.Gareth Jones Ali H.Bahkali Samantha C.Karunarathna Jian-Kui Liu J.jennifer luangsa-ard H.Thorsten Lumbsch Sajeewa S.N.Maharachchikumbura Eric H.C.McKenzie Jean-Marc Moncalvo Masoomeh Ghobad-Nejhad Henrik Nilsson Ka-Lai Pang Olinto L.Pereira Alan J.L.Phillips Olivier Raspé Adam W.Rollins Andrea I.Romero Javier Etayo Faruk Selçuk Steven L.Stephenson Satinee Suetrong Joanne E.Taylor Clement K.M.Tsui Alfredo Vizzini Mohamed A.Abdel-Wahab Ting-Chi Wen Saranyaphat Boonmee Dong Qin Dai Dinushani A.Daranagama Asha J.Dissanayake Anusha H.Ekanayaka S.C.Fryar Sinang Hongsanan Ruvishika S.Jayawardena Wen-Jing Li Rekhani H.Perera R.Phookamsak Nimali Ide Silva Kasun M.T.hambugala Qing Tian Nalin N.Wijayawardene Rui-Lin Zhao Qi Zhao Ji-Chuan Kang Itthayakorn Promputtha Center of Excellence in Fungal Research Mae Fah Luang UniversityChiang Rai 57100Thailand World Agro forestry Centre East and Central Asia Office 132 Lanhei RoadKunming 650201China Botany and Microbiology Department College of ScienceKing Saud UniversityRiyadh 1145Saudi Arabia Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha403108 GoaIndia Department of Botany Goa UniversityGoa 403206India Muséum National d’Histoire Naturelle Département Systématique et EvolutionCP 39ISYEBUMR 7205 CNRS MNHN UPMC EPHE12 Rue BuffonF-75005 ParisFrance State Key Laboratory of Mycology Institute of MicrobiologyChinese Academy of SciencesWest Beicheng RdBeijingChina Institute of Microbiology Beijing Forestry UniversityPO Box 61Beijing 100083China Plant Pathology Research Institute Agricultural Research Center(ARC)12619 GizaEgypt Botanic Garden Meise Department Bryophytes-Thallophytes(BT)Nieuwelaan 38B-1860 MeiseBelgium Fédération Wallonie-Bruxelles Direction Générale de l’Enseignement non obligatoire et de la Recherche scientifiqueRue A.Lavallée 11080 BruxellesBelgium Microbiology Division Research Center for BiologyIndonesian Institute of Sciences(LIPI)Jl.Raya Jakarta-Bogor KM 46Cibinong 16911West JavaIndonesia Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Microbe Interaction Laboratory(BMIT) BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Science&Education The Field Museum1400 S.Lake Shore DriveChicagoIL 60605USA Manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand Department of Natural History Royal Ontario Museumand Department of Ecology and Evolutionary BiologyUniversity of Toronto100 Queen’s ParkTorontoON M5S2C6Canada Department of Biotechnology Iranian Research Organiza

Taxonomic names are key links between various databases that store information on different *** global fungal nomenclural and taxonomic databases(notably Index Fungorum,Species Fungorum and MycoBank)can be sourced to find taxonomic details about fungi,while DNA sequence data can be sourced from NCBI,EBI and UNITE *** the sequence data may be linked to a name,the quality of the metadata is variable and generally there is no corresponding link to images,descriptions or herbarium *** is generally no way to establish the accuracy of the names in these genomic databases,other than whether the submission is from a reputable *** tackle this problem,a new database(FacesofFungi),accessible at ***(FoF)has been *** fungal database allows deposition of taxonomic data,phenotypic details and other useful data,which will enhance our current taxonomic understanding and ultimately enable mycologists to gain better and updated insights into the current fungal classification *** addition,the database will also allow access to comprehensive metadata including descriptions of voucher and type *** database is user-friendly,providing links and easy access between taxonomic ranks,with the classification system based primarily on molecular data(from the literature and via updated web-based phylogenetic trees),and to a lesser extent on morphological data when molecular data are *** FoF species are not only linked to the closest phylogenetic representatives,but also relevant data is provided,wherever available,on various applied aspects,such as ecological,industrial,quarantine and chemical *** data include the three main fungal groups(Ascomycota,Basidiomycota,Basal fungi)and fungus-like *** FoF webpage is an output funded by the Mushroom Research Foundation which is an NGO with seven directors with mycological *** webpage has 76 curators,and with the help of these s

关键词： Classification Database Faces of Fungi Fungi Phylogeny Taxonomy