检索结果-南通市图书馆

Clinical-based phenotypes in children with pediatric post-COVID-19 condition

World Journal of Pediatrics 2024年第7期20卷 682-691页

作者： Lieke C.E.Noij jelle m.blankestijn Coen R.Lap marlies A.van Houten Giske Biesbroek Anke-Hilse maitland-van der Zee mahmoud I.Abdel-Aziz Johannes B.van Goudoever mattijs W.Alsem Caroline L.H.Brackel Kim J.Oostrom Simone Hashimoto Suzanne W.J.Terheggen-Lagro Department of Pediatric Pulmonology and Allergy Amsterdam UMCLocation AMCEmma Children’s HospitalAmsterdam University Medical CenterRoom G2-222Meibergdreef 91105AZAmsterdamThe Netherlands Department of Pulmonary medicine Amsterdam UMCAmsterdamThe Netherlands Department of Pediatrics Spaarne GasthuisHoofddorpThe Netherlands Department of Pediatrics Emma Children’s HospitalAmsterdam University Medical CenterAmsterdamThe Netherlands Department of Rehabilitation medicine Amsterdam Movement SciencesMeibergdreef 9AmsterdamThe Netherlands Department of Paediatric Pulmonology Department of PaediatricsTergooi MCHilversumThe Netherlands Department of Child and Adolescent Psychiatry and Psychosocial Care Amsterdam UMCAmsterdam Reproduction and DevelopmentAmsterdamThe Netherlands

Background Pediatric post coronavirus disease 2019(COVID-19)condition(PPCC)is a heterogeneous syndrome,which can significantly affect the daily lives of *** study aimed to identify clinically meaningful phenotypes in children with PPCC,to better characterize and treat this *** Participants were children with physician-diagnosed PPCC,referred to the academic hospital Amsterdam UmC in the Netherlands between November 2021 and march *** factors and information on post-COVID symptoms,comorbidities,and impact on daily life were *** clusters were identified using an unsupervised and unbiased approach for mixed data *** Analysis of 111 patients(aged 3–18 years)revealed three distinct clusters within *** 1(n=62,median age=15 years)predominantly consisted of girls(74.2%).These patients suffered relatively more from exercise intolerance,dyspnea,and smell *** 2(n=33,median age=13 years)contained patients with an even gender distribution(51.5%girls).They suffered from relatively more sleep problems,memory loss,gastrointestinal symptoms,and *** 3(n=16,median age=11 years)had a higher proportion of boys(75.0%),suffered relatively more from fever,had significantly fewer symptoms(median of 5 symptoms compared to 8 and 10 for clusters 1 and 2 respectively),and experienced a lower impact on daily *** This study identified three distinct clinical PPCC phenotypes,with variations in sex,age,symptom patterns,and impact on daily *** findings highlight the need for further research to understand the potentially diverse underlying mechanisms contributing to post-COVID symptoms in children.

关键词： Adolescents Clusters Long COVID Pediatric Phenotypes Post-COVID syndrome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimizing ASReview Simulations:A generic multiprocessing Solution for“Light-data'and“Heavy-data'Users

引用

Data Intelligence 2024年第2期6卷 320-343页

作者： Sergei Romanov Abel Soares Siqueira Jonathan de Bruin jelle Teijema Laura Hofstee Rens van de Schoot Applied Data Science Department of Information and Computing ScienceFaculty of ScienceUtrecht University Netherlands eScienceCenter AmsterdamNL Department of Research and Data management Services Information Technology ServicesUtrecht UniversityUtrechtthe Netherlands Department of methodology and Statistics Faculty of Social and Behavioral SciencesUtrecht University

Active learning can be used for optimizing and speeding up the screening phase of systematic *** simulation studies mimicking the screening process can be used to test the performance of different machine-learning models or to study the impact of different training *** paper presents an architecture design withamultiprocessing computational strategyforrunningmanysuch simulation studiesinparallel,using the ASReview makita workflow generator and Kubernetes software for deployment with cloud *** provide a technical explanation of the proposed cloud architecture and its *** addition to that,we conducted 1140 simulations investigating the computational time using various numbers of CPUs and RAm *** analysis demonstrates the degree to which simulations can be accelerated with multiprocessing computing *** parallel computation strategy and the architecture design that was developed in the present paper can contribute to future research with more optimal simulation time and,at the same time,ensure the safe completion of the needed processes.

关键词： Active learning Systematic review Simulation study multiprocessing Cloud architecture

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Landscape spatial configuration is a key driver of wild bee demographics

引用

Insect Science 2018年第1期25卷 172-182页

作者： Lazaros Neokosmidis Thomas Tscheulin jelle Devalez Theodora Petanidou Laboratory of Biogeography and Ecology Department of Geography University of the Aegean University Hill Mytflene Greece

The majority of studies investigating the effects of landscape composition and configuration on bee populations have been conducted in regions of intensive agricultural production, ignoring regions which are dominated by seminatural habitats, such as the islands of the Aegean Archipelago. In addition, research so far has focused on the landscape impacts on bees sampled in cropped fields while the landscape effects on bees inhabiting seminatural habitats are understudied. Here, we investigate the impact of the landscape on wild bee assemblages in 66 phryganic （low scrubland） communities on 8 Aegean islands. We computed landscape metrics （total area and total perimete^area ratio） in 4 concentric circles （250, 500, 750, and 1000 m） around the center of each bee sampling site including 3 habitat groups （namely phrygana, cultivated land, and natural forests）. We further measured the local flower cover in 25 quadrats distributed randomly at the center of each sampling site. We found that the landscape scale is more important than the local scale in shaping abundance and species richness of bees. Furthermore, habitat configuration was more important than the total area of habitats, probably because it affects bees＇ movement across the landscape. Phrygana and natural forests had a positive effect on bee demographics, while cultivated land had a negative effect. This demonstrates that phryganic specialists drive bee assemblages in these seminatural landscapes. This finding, together with the shown importance of landscape scale, should be considered for the management of wild bees with special emphasis placed on the spatial configuration of seminatural habitats.

关键词： Aegean Archipelago landscape analysis landscape ecology olive groves phryganic vegetation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Self-assembled formation of long, thin, and uncoalesced GaN nanowires on crystalline TiN films

引用

Nano Research 2018年第1期11卷 565-576页

作者： David van Treeck Gabriele Calabrese jelle J. W. Goertz Vladimir m. Kaganer Oliver Brandt Sergio Fernandez-Garrido, Lutz Geelhaar PauI-Drude-lnstitut f~r Festk6rperelektronik Leibniz-lnstitut im Forschungsverbund Berlin e.V. Hausvogteiplatz 5-7 I 0117 Berlin Germany

We investigate in detail the self-assembled nucleation and growth of vertically oriented GaN nanowires by molecular beam epitaxy on crystalline TiN films. We demonstrate that this type of substrate allows for the growth of long and thin GaN nanowires that do not suffer from coalescence, a problem common to the growth on Si and other substrates. Only beyond a certain nanowire length that depends on the nanowire density and exceeds here 1.5 bun, coalescence takes place by bundling, i.e. the same process as on Si. By analyzing the nearest neighbor distance distribution, we identify the diffusion-induced repulsion of neighboring nanowires as the main mechanism limiting nanowire density during nucleation on TiN. Since on Si the final density is determined by shadowing of the impinging molecular beams by existing nanowires, it is the difference in adatom surface diffusion that enables the formation of nanowire ensembles with reduced density on TiN. These nanowire ensembles combine properties that make them a promising basis for the growth of core-shell heterostructures.

关键词： nanocolumn gallium nitride nucleation metal substrate coalescence core-shell

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Postoperative complications and weight loss following jejunostomy tube feeding after total gastrectomy for advanced adenocarcinomas

引用

Chinese Journal of Cancer Research 2017年第4期29卷 333-340页

作者： Hylke J.F. Brenkman Stephanie V.S. Roelen Elles Steenhagen jelle P. Ruurda Richard van Hillegersberg Cancer Center Department of Surgery University Medical Center Utrecht PO Box 85500 3508 GA Utrecht the Netherlands Internal medicine and Dermatology Department of Dietetics University Medical Center Utrecht PO Box 85500 3508 GA Utrecht the Netherlands Correspondence to R van Hillegersberg MD PhD. Department of Surgery University Medical Centre Utrecht G04.228 PO Box 85500 3508 GA

Objective： Patients undergoing total gastrectomy for cancer are at risk of malnourishment. The aim of this self- controlled study was to examine the effect of jejunostomy tube feeding （JTF） and other factors on postoperative weight and the incidence of jejunostomy-related complications in patients undergoing total gastrectomy for cancer. methods： All consecutive patients who underwent total gastrectomy for gastric cancer with jejunostomy plaeement were included from a prospective single-center database （2003-2014）. Jejunostomy-related complications and postoperative weight changes were evaluated up to 12 months after surgery. multivariable linear regression analysis was performed to identify factors associated with weight loss 12 months after gastreetomy. Results： Of 113 patients operated in the study period, 65 received JTF after total gastrectomy for a median duration of 18 d [interquartile range （IQR）, 10-55 d]. Jejunostomy-related complieations occurred in 11 （17%） patients, including skin leakage （n=3） and peritoneal leakage （n=2）, luxation （n=3）, occlusion （n=2）, infection （n=l） and torsion （n=l）. In 2 （3%） patients, a reoperation was needed due to jejtmostomy-related complications. The mean preoperative weight of patients was 71.8 kg （100%）, and remained stable during JTF （73.9 kg, 103%, P=0.331）. After JTF was stopped, the mean weight of patients decreased to 64.9 kg （90%） at 12 months after surgery （P〈0.001）. A high preoperative body mass index （BmI）（〉_25 kg/m2） was associated with high postoperative weight loss compared to patients with a low BmI （〈25 kg/m2）（16.3% vs. 8.6%, P=0.016）. Conclusions： JTF can prevent weight loss in the early postoperative phase. However, this is at the prize of possible complications. As weight loss in the long term is not prevented, routine JTF should be re-evaluated and balanced against the selected use in preoperatively malnourished patients. Special attention should be paid to patients with a high preoperative BmI, who ar

关键词： Gastric cancer total gastrectomy jejunostomy tube feeding weight

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dracunculiasis eradication-Finishing the job before surprises arise

引用

Asian Pacific Journal of Tropical medicine 2012年第7期5卷 505-510页

作者： Benjamin jelle Visser Academic medical Centre University of AmsterdamMeibergdreef 91105AZAmsterdamThe Netherlands

Dracunculiasis(Guinea worm disease) is a preventable waterborne parasitic disease that affects the poorest people living in remote rural areas in sub-Saharan African countries,who do not have access to safe drinking *** Guinea Worm Eradication Program,a 25-year old campaign to rid the world of Guinea Worm disease has now reached its final stage accelerating to zero cases in all endemic *** the 19th and 20th centuries,dracunculiasis was common in much of Southern Asia and the African *** overall number of cases has been reduced tremendously by≥99%,from the 3.32 million cases estimated to have occurred in 1986 in Africa to only I 797 cases reported in 2010 reported in only five countries(Sudan,mali,Ethiopia,Chad and Ghana) and Asia free of the *** achievement is unique in its kind - the only previously eradicated disease is smallpox,a viral infection for which vaccination was possible - and it has been achieved through primary community-based prevention and health education *** efforts need to be taken in two countries,South Sudan(comprising 94%or I 698 out of 1 797 of the cases reported world-wide in 2010) and mali because of frequent movements of nomads in a vast area inside and outside mali’s *** factors favourable to dracunculiasis eradication are available including adequate financial resources,community and political support and high levels of *** there is no reason that this disabling parasitic disease cannot be eradicated soon before surprises arise such as new civil conflicts in currently endemic countries.

关键词： Dracunculiasis Guinea worm disease Eradication

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Distribution,structure and biosynthetic gene families of(1,3;1,4)-β-glucan in Sorghum bicolor

引用

Journal of Integrative Plant Biology 2015年第4期57卷 429-445页

作者： Riksfardini A.Ermawar Helen m.Collins Caitlin S.Byrt Natalie S.Betts marilyn Henderson Neil J.Shirley Julian Schwerdt jelle Lahnstein Geoffrey B.Fincher Rachel A.Burton Australian Research Council Centre of Excellence in Plant Cell Walls University of Adelaide

In cereals, the presence of soluble polysaccharides including（1,3;1,4）-b-glucan has downstream implications for human health, animal feed and biofuel applications. Sorghum bicolor（L.） moench is a versatile crop, but there are limited reports regarding the content of such soluble ***, the amount of（1,3;1,4）-b-glucan present in sorghum tissues was measured using a megazyme assay. Very low amounts were present in the grain, ranging from 0.16%–0.27%（w/w）, while there was a greater quantity in vegetative tissues at 0.12–1.71%（w/w）. The fine structure of（1,3;1,4）-b-glucan, as denoted by the ratio of cellotriosyl and cellotetraosyl residues,was assessed by high performance liquid chromatography（HPLC） and ranged from 2.6–3：1 in the grain, while ratios in vegetative tissues were lower at 2.1–2.6：1. The distribution of（1,3;1,4）-b-glucan was examined using a specific antibody and observed with fl uorescence and transmission electron microscopy. micrographs showed a variable distribution of（1,3;1,4）-b-glucan in fl uenced by temporal and spatial factors. The sorghum orthologs of genes implicated in the synthesis of（1,3;1,4）-b-glucan in other cereals, such as the Cellulose synthase-like（Csl） F and H gene families were de *** pro filing of these genes across sorghum tissues was carried out using real-time quantitative polymerase chain reaction, indicating that, as in other cereals, Csl F6 transcripts dominated.

关键词： Cellulose synthase-like genes cell wall composition mixed-linkage glucan grain sorghum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

科学严谨的患者信息登记是高质量胃癌外科研究的基石——荷兰上消化道癌症审计数据库11年经验分享

引用

中华胃肠外科杂志 2023年第2期26卷 148-153页

作者：王敬普 Eline m de Groot maurits R Visser misha D.P Luyer jelle P Ruurda Richard van Hillegersberg 荷兰乌特勒支大学医学中心外科部荷兰乌特勒支3584CX 荷兰临床审计研究所科学局荷兰莱顿2333AA 凯瑟琳那医院外科部荷兰埃因霍温5623EJ

随着过去数十年微创技术、围手术期康复干预和集中化医疗制度的逐步应用,胃癌术后30 d病死率和并发症发生率有了显著改善。然而,当前阶段的胃癌术后短期预后依然不容乐观,可能对胃癌手术治疗的疗效产生严重的负面影响,仍有很大的改善空... 详细信息

随着过去数十年微创技术、围手术期康复干预和集中化医疗制度的逐步应用,胃癌术后30 d病死率和并发症发生率有了显著改善。然而,当前阶段的胃癌术后短期预后依然不容乐观,可能对胃癌手术治疗的疗效产生严重的负面影响,仍有很大的改善空间。高质量的临床研究是分析治疗结果和评估新治疗策略的重要工具。因此,严谨的胃癌患者信息登记作为高质量外科研究的基础应受到足够重视。在过去的11年里,荷兰上消化道癌症审计(DUCA)数据库在上消化道肿瘤患者的数据登记和维护方面拥有丰富的经验,它在数据登记、数据质量控制、数据申请和使用以及数据安全等方面采取的有效措施,使得该数据库中患者数据的质量保持在较高水平。这些数据已被广泛用于医疗质量监测和科学研究,对改善上消化道癌症患者的术后短期预后产生了非常积极的影响。DUCA的工作可能对建立基于人群的临床数据库具有一定的参考价值。

关键词：胃肿瘤并发症荷兰上消化道癌症审计,数据库

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

从比利时走向世界--访《自我主义者》影片主创

引用

北京电影学院学报 2015年第2期 75-78页

作者： jelle Stroo Stephanie Delbecque 李思雪北京电影学院电影学系不详

悬疑剧情影片《自我主义者》是比利时导演jelle Stroo的处女作,为入选第五届北京国际电影节注目未来国际展映单元的竞赛影片之一。2015年4月18日,导演本人协同他的妻子兼制片人Stephanie Delbecque接受了本刊的采访。拍摄本片之前,jelle... 详细信息

悬疑剧情影片《自我主义者》是比利时导演jelle Stroo的处女作,为入选第五届北京国际电影节注目未来国际展映单元的竞赛影片之一。2015年4月18日,导演本人协同他的妻子兼制片人Stephanie Delbecque接受了本刊的采访。拍摄本片之前,jelle Stroo曾长期从事影片剪辑的工作,拍摄过多部短片。4月22日,本片在注目未来单元进行了其国际首映。

关键词：自我主义国际电影节影片剪辑主创走向世界商业片单元的灵感来源北京电影学院专业演员

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Worldwide practice in gastric cancer surgery

引用

World Journal of Gastroenterology 2016年第15期22卷 4041-4048页

作者： Hylke JF Brenkman Leonie Haverkamp jelle P Ruurda Richard van Hillegersberg Department of Surgery University Medical Center Utrecht

AIm: To evaluate the current status of gastric cancer surgery ***: An international cross-sectional survey on gastric cancer surgery was performed amongst international upper gastro-intestinal surgeons. All surgical members of the International Gastric Cancer Association were invited by e-mail to participate. An English web-based survey had to be filled in with regard to their surgical preferences. Questions asked included hospital volume, the use of neoadjuvant treatment, preferred surgical approach, extent of the lymphadenectomy and preferred anastomotic technique. The invitations were sent in September 2013 and the survey was closed in January ***: The corresponding specific response rate was 227/615(37%). The majority of respondents: originated from Asia( 5 4 %), performed > 2 1 gastrectomies per year(79%) and used neoadjuvant chemotherapy(73%). An open surgical procedure was performed by the majority of surgeons for distal gastrectomy for advanced cancer(91%) and total gastrectomy for both early and advanced cancer(52% and 94%). A minimally invasive procedure was preferred for distal gastrectomy for early cancer(65%). In Asia surgeons preferred a minimally invasive procedure for total gastrectomy for early cancer also(63%). A D1+ lymphadenectomy was preferred in early gastric cancer(52% for distal, 54% for total gastrectomy) and a D 2 lymphadenectomy was preferred in advanced gastric cancer(93% for distal, 92% for total gastrectomy) CONCLUSION: Surgical preferences for gastric cancer surgery vary between surgeons worldwide. Although the majority of surgeons use neoadjuvant chemotherapy, minimally invasive techniques are still not widely adapted.

关键词： Gastric cancer Gastrectomy Laparoscopy neoplasm minimally invasive surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：