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Effect of special types of bread with select herbal components on postprandial glucose levels in diabetic patients

World Journal of Diabetes 2024年第4期15卷 664-674页

作者： Drasko M Gostiljac Srdjan S Popovic Vesna Dimitrijevic-Sreckovic Sasa M Ilic jelena a jevtovic Dragan M Nikolic Ivan A Soldatovic Clinic for Endocrinology Diabetes and Metabolic DiseasesUniversity Clinical Centre of SerbiaBelgrade 11000Serbia Faculty of Medicine University of BelgradeBelgrade 11000Serbia Clinic for Gastroenterology and Hepatology University Clinical Centre of SerbiaBelgrade 11000Serbia Clinic for Endocrinology Diabetes and Metabolic Diseases-Laboratory for Human Pancreatic Islets CultureUniversity Clinical Centre of SerbiaBelgrade 11000Serbia

BACKGROUND Nutrition recommendations in patients with type 2 diabetes mellitus(T2DM)are to consume rye or integral bread instead of white bread.A positive effect on glucoregulation has been achieved by enriching food with various biologically active substances of herbal origin,so we formulated an herbal mixture that can be used as a supplement for a special type of bread(STB)to achieve better effects on postprandial glucose and insulin levels in patients with *** To compare organoleptic characteristics and effects of two types of bread on postprandial glucose and insulin levels in T2DM *** This trial included 97 patients with T2DM.A parallel group of 16 healthy subjects was also *** participants were given 50 g of rye bread and the same amount of a STB with an herbal mixture on 2 consecutive *** blood glucose and insulin levels were compared at the 30^(th),60^(th),90^(th) and 120th min.A questionnaire was used for subjective estimation of the organoleptic and satiety features of the two types of *** Compared to patients who consumed rye bread,significantly lower postprandial blood glucose and insulin concentrations were found in T2DM patients who consumed *** relevant differences were found among the healthy *** estimated organoleptic and satiety characteristics are better for STB than for rye *** STB have better effects than rye bread on postprandial glucoregulation in T2DM *** estimated organoleptic and satiety characteristics are better for STB than for rye ***,STB can be recommended for nutrition in T2DM patients.

关键词： Special types of bread Postprandial glucoregulation Insulin Nutrition Type 2 diabetes mellitus

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