检索结果-南通市图书馆

Liver biopsy in a district general hospital:Changes over two decades

World Journal of Gastroenterology 2007年第40期13卷 5336-5342页

作者： Wing-Kin Syn Caroline Bruckner-Holt Adam Farmer Sarah Howdle jeffrey Bateman Liver and Hepatobiliary Unit Queen Elizabeth HospitalBirminghamB 15 2THUnited Kingdom Department of Gastroenterology Princess Royal HospitalTelfordUnited Kingdom Department of Gastroenterology City HospitalBirminghamUnited Kingdom Department of Radiology Princess Royal HospitalYelfordUnited Kingdom

AIM： To study liver biopsy practice over two decades in a district general hospital in the United Kingdom.METHODS： We identified all patients who had at least one liver biopsy between 1986 and 2006 from the databases of the radiology and gastroenterology departments. Subjects with incomplete clinical data were excluded from the study.RESULTS： A total of 103 liver biopsies were performed. Clinical data was available for 88 patients, with 95 biopsies. Between 1986 and 1996, 18 （95%） out of the 19 liver biopsies performed were blind and 6 （33%） were for primary biliary cirrhosis. Between 1996 and 2006, 14 （18%） out of 76 biopsies were blind; and the indications were abnormal liver tests （33%）, hepatitis C （12%） and targeted-biopsies （11%）. Liver biopsies were unhelpful in 5 （50） subjects. Pain was the most common complication of liver biopsy （5%）. No biopsy-related mortality was reported. There was a trend towards more technical failures and complications with the blind biopsy technique.CONCLUSION： Liver biopsies performed in small district hospitals are safe and useful for diagnostic and staging purposes. Abnormal liver tests, non-alcoholic fatty liver disease and targeted biopsies are increasingly common indications. Ultrasound-guided liver biopsies are now the preferred method and are associated with fewer complications.

关键词： Complication District general Indication Liver biopsy Non-alcoholic fatty liver

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Chapman-Richards Distribution and its Relationship to the Generalized Beta

引用

Forest Ecosystems 2019年第3期6卷 219-235页

作者： jeffrey H.Gove Thomas B.Lynch Mark J.Ducey USDA Forest Service Northern Research Station271 Mast Road Durham 03824NHUSA Professor Emeritus Department of Natural Resource Ecology and ManagementOklahoma State UniversityAg Hall Room 008CStillwater 74078OKUSA Department of Natural Resources and the Environment University of New Hampshire114 James Hall Durham 03824NHUSA

Background: The Chapman-Richards distribution is developed as a special case of the equilibrium solution to the McKendrick-Von Foerster equation. The Chapman-Richards distribution incorporates the vital rate assumptions of the Chapman-Richards growth function, constant mortality and recruitment into the mathematical form of the distribution. Therefore, unlike 'assumed' distribution models, it is intrinsically linked with the underlying vital rates for the forest area under consideration. Methods: It is shown that the Chapman-Richards distribution can be recast as a subset of the generalized beta distribution of the first kind, a rich family of assumed probability distribution models with known properties. These known properties for the generalized beta are then immediately available for the Chapman-Richards distribution, such as the form of the compatible basal area-size distribution. A simple two-stage procedure is proposed for the estimation of the model parameters and simulation experiments are conducted to validate the procedure for four different possible distribution shapes. Results: The simulations explore the efficacy of the two-stage estimation procedure;these cover the estimation of the growth equation and mortality-recruitment derives from the equilibrium assumption. The parameter estimates are shown to depend on both the sample size and the amount of noise imparted to the synthetic measurements. The results vary somewhat by distribution shape, with the smaller, noisier samples providing less reliable estimates of the vital rates and final distribution forms. Conclusions: The Chapman-Richards distribution in its original form, or recast as a generalized beta form, presents a potentially useful model integrating vital rates and stand diameters into a flexible family of resultant distributions shapes. The data requirements are modest, and parameter estimation is straightforward provided the minimal recommended sample sizes are obtained.

关键词： Diameter distributions Chapman-Richards growth Generalized beta distribution of the first kind Maximum likelihood McKendrick-Von Foerster equation Physiologically structured population model Size-structured distributions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Plasticity of floral sex allocation within inflorescences of hermaphrodite Aconitum gymnandrum

引用

Journal of Plant Ecology 2015年第2期8卷 130-135页

作者： Zhi-Gang Zhao Zuo-Jun Liu jeffrey K.Conner State Key Laboratory of Grassland and Agro-Ecosystems School of Life SciencesLanzhou University222 Tianshui Road Chengguan DistrictLanzhou 730000China College of Life Science and Engineering Lanzhou University of Technology287 Langongpin Road Qilihe DistrictLanzhou 730000China Kellogg Biological Station and Department of Plant Biology Michigan State University3700 East Gull Lake DriveHickory CornersMI 49060USA

Aims sex allocation in plants is often plastic,enabling individuals to adjust to variable ***,the predicted male-biased sex allocation in response to low resource conditions has rarely been experimentally tested in hermaphroditic *** particular,it is unknown whether distal flowers in linear inflorescences show a larger shift to male allocation relative to basal flowers when resources are *** this study,we measure position-depend-ent plasticity of floral sex allocation within racemes of Aconitum gymnandrum in response to reduced resource *** using a defoliation treatment in the field applied to potted plants from a nested half-sibling design,we examined the effects of the treatment,flower position,family and their *** Findingsallocation to male function increased with more distal flower posi-tion,while female allocation either did not change with position or declined at the most distal *** significantly reduced the mass of both the androecium and gynoecium,but not anther number or carpel *** mass declined more strongly with defoliation than did androecial mass,resulting in a significant increase in the androecium/gynoecium ratio as predicted by sex allocation *** responses of androecium mass and gynoecium mass were affected by flower position,with less mass lost in basal flowers,but similar plastic magnitude in both sexual traits across flower position lead to consistent variation in the androecium/gynoecium ratio along the inflorescence.a sig-nificant treatment*paternal family interaction for the androecium/gynoecium ratio is evidence for additive genetic variation for plastic floral sex allocation,which means that further evolution of alloca-tion can occur.

关键词： Aconitum gymnandrum sex allocation plasticity inflorescence architecture

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Complete loss of RNA editing from the plastid genome and most highly expressed mitochondrial genes of Welwitschia mirabilis

引用

Science China(Life Sciences) 2019年第4期62卷 498-506页

作者： Weishu Fan Wenhu Guo Lexis Funk jeffrey P.Mower Andan Zhu Germplasm Bank of Wild Species Kunming Institute of Botany Chinese Academy of Sciences Center for Plant Science Innovation University of Nebraska Department of Agronomy and Horticulture University of Nebraska School of Biological Sciences University of Nebraska

Comparative genomics among gymnosperms suggested extensive loss of mitochondrial RNA editing sites from Welwitschia mirabilis based on predictive analysis. However, empirical or transcriptome data to confirm this massive loss event are lacking,and the potential mechanisms of RNA site loss are unclear. By comparing genomic sequences with transcriptomic and reversetranscription PCR sequencing data, we performed a comprehensive analysis of the pattern of RNA editing in the mitochondrial and plastid genomes(mitogenome and plastome, respectively) of W. mirabilis and a second gymnosperm, Ginkgo biloba. For ***, we found only 99 editing sites located in 13 protein-coding genes in the mitogenome and a complete loss of RNA editing from the plastome. The few genes having high editing frequency in the Welwitschia mitogenome showed a strong negative correlation with gene expression level. Comparative analyses with G. biloba, containing 1,405 mitochondrial and 345 plastid editing sites, revealed that the editing loss from W. mirabilis is mainly due to the substitution of editable cytidines to thymidines at the genomic level, which could be caused by retroprocessing. Our result is the first study to uncover massive editing loss from both the mitogenome and plastome in a single genus. Furthermore, our results suggest that gene expression level and retroprocessing both contributed to the evolution of RNA editing in plant organellar genomes.

关键词： RNA editing massive loss expression levels organelle genomes Welwitschia

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High Oxygen Nanocomposite Barrier Films Based on Xylan and Nanocrystalline Cellulose

引用

Nano-Micro Letters 2010年第4期2卷 235-241页

作者： Amit Saxena Thomas J.Elder jeffrey Kenvin Arthur J.Ragauskas School of Chemistry and Biochemistry Georgia Institute of Technology USDA-Forest Service Southern Research Station Micromeritics Instrument Corporation

The goal of this work is to produce nanocomposite film with low oxygen permeability by casting an aqueous solution containing xylan,sorbitol and nanocrystalline *** morphology of the resulting nanocomposite films was examined by scanning electron microscopy and atomic force microscopy which showed that control films containing xylan and sorbitol had a more open structure as compared to xylan-sorbitol films containing sulfonated nanocrystalline *** average pore diameter,bulk density,porosity and tortuosity factor measurements of control xylan films and nanocomposite xylan films were examined by mercury intrusion porosimetry *** films reinforced with nanocrystalline cellulose were denser and exhibited higher tortuosity factor than the control xylan *** xylan films had average pore diameter,bulk density,porosity and tortuosity factor of 0.1730 μm,0.6165 g/ml,53.0161% and 1.258,respectively as compared to xylan films reinforced with 50% nanocrystalline cellulose with average pore diameter of 0.0581 μm,bulk density of 1.1513 g/ml,porosity of 22.8906% and tortuosity factor of *** transmission rate tests demonstrated that films prepared with xylan,sorbitol and 5%,10%,25% and 50% sulfonated nanocrystalline cellulose exhibited a significantly reduced oxygen permeability of 1.1387,1.0933,0.8986 and 0.1799 cm^3×μm/m^2×d×k Pa respectively with respect to films prepared solely from xylan and sorbitol with a oxygen permeability of 189.1665 cm^3×μm/m^2×d×k *** properties suggested these nanocomposite films have promising barrier properties.

关键词： Nanocomposites Xylan Nanocrystalline cellulose Oxygen barrier

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

David Foster Wallace's balancing books

David Foster Wallace's balancing books

引用

作者： jeffrey Severs.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

作者： jeffrey Ford.

学校读者我要写书评

暂无评论

The Essential Cosmic Perspective jeffrey Bennett...[et al.]. 2nd ed.

引用

2003年

作者： jeffrey Bennett...[et al.].

Edition of: The cosmic perspective, designed for one-term courses in introductory astronomy.

ISBN: (纸本)0805385843

Edition of: The cosmic perspective, designed for one-term courses in introductory astronomy.

关键词： Astronomy.

来源：畅想之星图书光盘版（南... 评论

在线全文

畅想之星图书光盘版（南通市图书馆镜像）

学校读者我要写书评

暂无评论

Surviving genocide

Surviving genocide

引用

作者： jeffrey Ostler.

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

The therapeutic implications of immunosuppressive tumor aerobic glycolysis

引用

Cellular & Molecular Immunology 2022年第1期19卷 46-58页

作者： Bradley I.Reinfeld WKimryn Rathmell Tae Kon Kim jeffrey C.Rathmell Department of Medicine Division of Hematology and OncologyVanderbilt University Medical CenterNashvilleTNUSA

In 2011,Hanahan and Weinberg added“Deregulating Cellular Energetics”and“Avoiding Immune Destruction”to the six previous hallmarks of *** this seminal paper,there has been a growing consensus that these new hallmarks are not mutually exclusive but rather *** following review summarizes how founding genetic events for tumorigenesis ultimately increase tumor cell glycolysis,which not only supports the metabolic demands of malignancy but also provides an immunoprotective niche,promoting malignant cell proliferation,maintenance and *** mechanisms by which altered metabolism contributes to immune impairment are multifactorial:(1)the metabolic demands of proliferating tumor cells and activated immune cells are similar,thus creating a situation where immune cells may be in competition for key nutrients;(2)the metabolic byproducts of aerobic glycolysis directly inhibit antitumor immunity while promoting a regulatory immune phenotype;and(3)the gene programs associated with the upregulation of glycolysis also result in the generation of immunosuppressive cytokines and *** this perspective,we shed light on important considerations for the development of new classes of agents targeting cancer *** types of therapies can impair tumor growth but also pose a significant risk of stifling antitumor immunity.

关键词： cancer metabolism immuno logy glycolysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：