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Integrative Zoology 2016年第4期11卷 240-249页

作者： Andrea CONTINA Eli S.BRIDGE jeffrey F.KELLY Oklahoma Biological Survey University of OklahomaNormanOklahomaUSA Department of Biology University of OklahomaNormanOklahomaUSA

To search for genes associated with migratory phenotypes in songbirds,we selected candidate genes through annotations from the Mouse Genome Informatics database and assembled an extensive candidate-gene ***,we implemented a next-generation sequencing approach to obtain DNA sequences from the Painted Bunting *** focused on those sequences that were conserved across avian species and that aligned with candidate genes in our mouse *** genotyped short sequence repeats from the following candidate genes:ADRA1d,ANKRD17,CISH and *** studied the possible correlations between allelic variations occurring in these novel candidate migration genes and avian migratory phenotypes available from the published lit*** found that allele variation at MYH7 correlated with a calculated index of speed of migration(km/day)across 11 species of *** highlight the potential of the Mouse Genome Informatics database in providing new candidate genes that might play a crucial role in regulating migration in birds and possibly in other *** research effort shows the benefits and limitations of working with extensive genomic datasets and offers a snapshot of the challenges related to cross-species validation in behavioral and molecular ecology studies.

关键词： avian migration candidate gene approach Mouse Genome Informatics MYH7 songbirds

Rapid earthquake focal mechanism inversion using high-rate GPS velometers in sparse network

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Science China Earth Sciences 2015年第11期58卷 1970-1981,1页

作者： GUO AiZhi NI SiDao CHEN WeiWen jeffrey T.FREYMUELLER SHEN ZhiChao State Key Laboratory of Geodesy and Earth's Dynamics Institute of Geodesy and Geophysics Chinese Academy of Sciences School of Earth and Space Sciences University of Science and Technology of China Geophysical Institute University of Alaska Fairbanks

In this study, we demonstrate an approach for inverting earthquake source parameters based on high-rate global positioning system （GPS） velocity seismograms. The velocity records obtained from single-station GPS velocity solutions with broadcast ephemeris are used directly for earthquake source parameter inversion using the Cut and Paste method, without requiring conversion of the velocity records into displacement records. Taking the E1 Mayor-Cucapah earthquake as an example, GPS velocity records from 10 stations with reasonable azimuthal coverage provide earthquake source parameters very close to those from the Global centroid moment tensor （Global CMT） solution. In sparse network tests, robust source parameters with acceptable bias can be achieved with as few as three stations. When the number of stations is reduced to two, the bias in rake angle becomes appreciable, but the magnitude and strike estimations are still robust. The results of this study demonstrate that rapid and reliable estimation of earthquake source parameters can be obtained from GPS velocity data. These parameters could be used for early earthquake warning and shake map construction, because such GPS velocity records can be obtained in real time.

关键词： high-rate GPS velometer GPS velocity determination CAP method earthquake source parameters sparse network

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Biodiversity, Conservation and Protected Areas can Contribute to Development in Asia： how Local Communities

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生物多样性 1994年第B11期2卷 75-87页

作者： jeffrey A. McNEELY Chief Biodiversity Officer IUCN 1196 Gland Swizerland

Stem Cell Ophthalmology Treatment Study(SCOTS) for retinal and optic nerve diseases: a case report of improvement in relapsing auto-immune optic neuropathy

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Neural Regeneration Research 2015年第6期10卷 1507-1515页

作者： jeffrey N.Weiss Steven Levy Susan C.Benes Retina Associates of South Florida MD Stem Cells Wilmer Eye Institute The Johns Hopkins Hospital

We present the results from a patient with relapsing optic neuropathy treated within the Stem Cell Ophthalmology Treatment Study （SCOTS）. SCOTS is an Institutional Review Board ap- proved clinical trial and has become the largest ophthalmology stem cell study registered at the National Institutes of Health to date （*** Identifier NCT 01920867）. SCOTS utilizes autologous bone marrow-derived stem cells （BMSCs） for treatment of retinal and optic nerve diseases. Pre-treatment and post-treatment comprehensive eye exams of a 54 year old female patient were performed both at the Florida Study Center, USA and at The Eye Center of Columbus, USA. As a consequence of a relapsing optic neuritis, the patient＇s previously normal visual acuity decreased to between 20/350 and 20/400 in the right eye and to 20/70 in the left eye. Significant visual field loss developed bilaterally. The patient underwent a right eye vitrectomy with injection of BMSCs into the optic nerve of the right eyeand retrobulbar, subtenon and in- travitreal injection of BMSCs in the left eye. At 15 months after SCOTS treatment, the patient＇s visual acuity had improved to 20/150 in the right eye and 20/20 in the left eye. Bilateral visual fields improved markedly. Both macular thickness and fast retinal nerve fiber layer thickness were maximally improved at 3 and 6 months after SCOTS treatment. The patient also reduced her mycophenylate dose from 1,500 mg per day to 500 mg per day and required no steroid pulse therapy during the 15-month follow up.

关键词： nerve regeneration stem cells optic nerve autoimmune optic neuropathy ophthalmology bone marrow-derived stem cells blindness visual loss Stem Cell Ophthalmology Treatment Study neural regeneration

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SUSTAINABLE PLAYING FIELDS 8 Steps to an Easy Field Facelift

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Journal of Green Building 2010年第2期5卷 27-31页

作者： jeffrey T.Fowler The Pennsylvania State University Cooperative Extension

According to the National Safe Kids Coalition,30 million young people play organized sports in the United States *** million of them are treated annually in an emergency room and 50%of those treated injuries are *** more people are encouraged to be active in their daily lives to combat health issues and obesity,an increased demand on recreational and sport facilities and playing surfaces will increase the degradation of the playing surfaces and thereby increase the risk of sports related *** maintenance and upkeep of playing surfaces can be become a sinkhole for budgeted dollars if a facility use plan and a maintenance plan are not in place for dealing with the increase in play on athletic fields and *** why do the statistics of athletic injury matter?As we manage sports fields,our jobs are to reduce the number of injuries on our playing *** need to make our fields as safe as we *** are a number of agronomic practices that many times are overlooked or forgotten about when managing sports turf.“8 Steps to an Easy Field Facelift”is a list of the management practices we can employ that will sustain our fields safer for play for a longer period of time at minimal cost.

关键词： play field sustainability athletic field safety landscape management field safety turf management lawn care

Co-occurrence prediction in a large location-based social network

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Frontiers of Computer Science 2013年第2期7卷 185-194页

作者： Rong-Hua LI Jianquan LIU jeffrey Xu YU Hanxiong CHEN Hiroyuki KITAGAWA Department of System Engineering and Engineering Management The Chinese University of Hong Kong Hong Kong China Faculty of Engineering Information and systems University of TsukubaJapan Ibaraki 305-8577 Cloud System Research Laboratories NEC CorporationJapan Tokyo 108-8001

Location-based social network （LBSN） is at the forefront of emerging trends in social network services （SNS） since the users in LBSN are allowed to ＂check-in＂ the places （locations） when they visit them. The accurate geographi- cal and temporal information of these check-in actions are provided by the end-user GPS-enabled mobile devices, and recorded by the LBSN system. In this paper, we analyze and mine a big LBSN data, Gowalla, collected by us. First, we investigate the relationship between the spatio-temporal co- occurrences and social ties, and the results show that the co- occurrences are strongly correlative with the social ties. Sec- ond, we present a study of predicting two users whether or not they will meet （co-occur） at a place in a given future time, by exploring their check-in habits. In particular, we first intro- duce two new concepts, bag-of-location and bag-of-time-lag, to characterize user＇s check-in habits. Based on such bag rep- resentations, we define a similarity metric called habits sim- ilarity to measure the similarity between two users＇ check-in habits. Then we propose a machine !earning formula for pre- dicting co-occurrence based on the social ties and habits sim- ilarities. Finally, we conduct extensive experiments on our dataset, and the results demonstrate the effectiveness of the proposed method.

关键词： location-based social networks Gowalla co-occurrence

Thermal conductivity of complex materials

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National Science Review 2019年第3期6卷 380-381页

作者： G.jeffrey Snyder Matthias T.Agne Ramya Gurunathan Department of Materials Science and Engineering Northwestern University

In the discussion and analysis of thermal properties (e.g. heat capacity, thermal conductivity) the Debye approximation is typically used to describe the collective behavior of lattice vibrations (phonons) in solid ma... 详细信息

关键词： Thermal conductivity of complex materials

Cellular and molecular mechanisms implicated in pathogenesis of selective neurodegeneration in Huntington＇s disease

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Frontiers of physics 2012年第5期7卷 459-476页

作者： jeffrey R CANTLE Center for Neurobehavioral Genetics Semel Institute for Neuroscience & Human Behavior David Geffen School of Medicine at UCLA_ University of California Los Angeles CA 90095 USA DepartmentofPsychiatry & Biobehavioral Sciences David Geffen School of Medicine at UCLA University of California Los Angeles CA 90095 USA Brain Research Institute. David Geffen School of Medicine at UCLA University of California Los Angeles CA 90095 USA Interdepartmental Program for Neuroscience David Geffen School of Medicine at UCLA University of CaliJbrnia Los Angeles CA 90095 USA

Huntington＇s disease （HD） is one of the most common dominantly-inherited neurodegenerative disorders and is caused by a CAG repeat expansion in the huntingtin gene. HD is characterized by selective degeneration of subpopulations of neurons in the brain, however the precise underlying mechanisms how a ubiquitously expressed disease protein could target specific types of neurons for degeneration remains a critical, yet unanswered question for HD and other major neurodegenerative disorders. In this review, we describe the expanding view of selective neuronal vulnerability in HD, based on recent neuropathological and neuroimaging studies. We will also summarize the systematic effort to define the cell types in which mutant Huntingtin expression is critical for pathogenesis of vulnerable neurons in the striatum and cortex. Finally, we will describe selected, emerging molecular mechanisms that are implicated in selective disease processes in HD. Together, the field has begun to appreciate the distinct molecular pathogenic roles of mutant huntingtin in different cell types that may contribute to the selective neuronal vulnerability, with dissection of such mechanisms likely to yield novel molecular targets for HD therapy.

关键词： Huntington's disease neurodegeneration selective neuronal vulnerability cortex striatum conditional mouse model cell-autonomous toxicity pathological cell-cell interaction pathogenesis therapeutic targets

Practical business math procedures / jeffrey Slater. brief 8th ed.

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Organic Carbon in the Surface Sediments from the Intensive Mariculture Zone of Sanggou Bay: Distribution, Seasonal Variations and Sources

2006年

作者： jeffrey Slater.

Includes index.

ISBN: (纸本)0072967250

Includes index.

关键词： Business mathematics

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Journal of Ocean University of China 2019年第4期18卷 985-996页

作者： SUI Juanjuan ZHANG Jihong REN S. jeffrey LIN Fan Yellow Sea Fisheries Research Institute Chinese Academy of Fishery Sciences Qingdao 266071 China Function Laboratory for Marine Fisheries Science and Food Production Processes Qingdao National Laboratory for Marine Science and Technology Qingdao 266237 China Function Laboratory for Marine Fisheries Science and Food Production Processes Qingdao National Laboratory for Marine Science and Technology Qingdao 266237 China

Mariculture has rapidly grown worldwide, which might greatly influence the biogeochemical cycle of organic carbon in coastal seas. In this study, several geochemical parameters, including grain size composition, sedimentary total organic carbon (TOC), total nitrogen (TN), stable carbon (δ13C) and nitrogen (δ15N) isotopic compositions, were analyzed for surface sediments collected from different mariculture zones of Sanggou Bay and in different seasons. We investigated the composition and distribution of or- ganic matter in surface sediments and further evaluated the contribution of mariculture activities to TOC sources. The TOC and TN contents (mass percentage) in the bay were in the range of 0.14% to 1.45% and 0.03% to 0.20%, respectively. The spatial distribution indicated that sedimentary TOC and TN contents in shellfish monoculture and shellfish-kelp polyculture zones were higher than in other mariculture zones, which might be related to grain size composition and mariculture organisms. Seasonal variations of TOC contents were observed in different mariculture zones. The TOC/TN atomic ratio (C/N),δ13C and δ15N were in the ranges of 5.97 to 10.97, 21.76‰ to 13.14‰ and 2.13‰ to 8.08‰, respectively, implying that sedimentary organic matter in Sanggou Bay was the mixture of marine phytoplankton, terrestrial and maricultural sources. A simple mixing model based on δ13C was applied and the results indicated that the relative contributions of organic carbon sources in Sanggou Bay followed the order kelp (36.6%) marine phytoplankton (28.7%) shellfish bio-deposition (23.8%) terrestrial input (10.9%). Surface sediments in Sanggou Bay were domi- nated by mariculture-derived organic carbon, which on average accounted for 60.4% of TOC.

关键词： sediment organic carbon sources mariculture Sanggou Bay Iso-Source

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