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英国医学杂志中文版 2018年第5期21卷 297-297页

作者：毛晨晖(译) 北京协和医院神经科

背景和目的我们实验室最近的报告显示大鼠缺血后各种基质金属蛋白酶（MMPs）的表达情况以及MMP-12住卒中后脑损伤中的有害作用。我们假设卒中后MMPs调节功能障碍在不同物种间类似存在。

关键词：卒中后基质金属蛋白酶蛋白酶-12基因

East Asian.VLBI n.twork observation. of active galactic n.clei jets:imagin. with KaVA+Tian.a+n.n.han

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Research in.Astron.my an. Astrophysics 2021年第8期21卷 220-234页

作者： Yu-Zhu Cui Kazuhiro Hada Motoki Kin. Bon.-Won.Sohn.Jon.ho Park Hyun.Wook Ro Satoko Sawada-Satoh Wu Jian. Lan. Cui Mareki Hon.a Zhi-Qian. Shen.Fumie Tazaki Tao An.Ilje Cho Guan.-Yao Zhao Xiao-Pen. Chen. Kotaro n.in.ma Kiyoaki Wajima Yin.-Kan. Zhan. n.riyuki Kawaguchi Juan.Carlos Algaba Shoko Koyama Tomoya Hirota Yoshin.ri Yon.kura n.buyuki Sakai Bo Xia Yon.-Bin.Jian. Lin.Fen. Yu Wei Gou Ju-Yeon.Hwan. Yon.-Chen.Jian. Yun.Xia Sun.Don.-Kyu Jun. Hyo-Ryoun. Kim Jeon.-Sook Kim Hideyuki Kobayashi Jee-Won.Lee Jeon.-Ae Lee Hua Zhan. Guan.-Hui Li Zhi-Qian. Xu Pen. Li Jun.-Hwan.Oh Se-Jin.Oh Chun.-Sik Oh Tomoaki Oyama Duk-Gyoo Roh Katsun.ri-M.Shibata Wen.Guo Ron.-Bin. Zhao Wei-Ye Zhon. Jin.Qin. Wan. Wen.Jun.Yan. Hao Yan.Jae-Hwan.Yeom Bin.Li Xiao-Fei Li Jian.Pin. Yuan.Jian.Don. Zhon. Chen.Kazun.ri Akiyama Keiichi Asada Do-Youn. Byun.Yoshiaki Hagiwara jeffrey Hodgson.Tae-Hyun.Jun. Kee-Tae Kim San.-Sun. Lee Kun.oo Yi Qin.-Hui Liu Xian. Liu Ru-Sen.Lu Masan.ri n.kamura Sascha Trippe n. Wan. Xue-Zhen. Wan. Bo Zhan. Departmen. of Astron.mical Scien.e The Graduate University for Advanced StudiesSOKENDAI2-21-1 OsawaMitakaTokyo 181-8588Japan Mizusawa VLBI Observatory National Astronomical Observatory of Japan2-12 HoshigaokaMizusawaOshuIwate 023-0861Japan Kogakuin.Un.versity of Techn.logy an. En.in.erin. Academic Support Center2665-1 NakanoHachiojiTokyo 192-0015Japan Korea Astron.my an. Space Scien.e In.titute Yuseong-guDaejeon 34055Korea Departmen. of Astron.my Yonsei University50 Yonsei-roSeodaemun-guSeoul 03722Korea Departmen. of Astron.my an. Space Scien.e University of Science and Technology217 Gajeong-roDaejeonKorea In.titute of Astron.my an. Astrophysics Academia Sinica645 N Aohoku PIHiloHI 96720USA Graduate School of Scien.es an. Techn.logy for In.ovation Yamaguchi UniversityYoshida 1677-1YamaguchiYamaguchi 753-8512Japan Shan.hai Astron.mical Observatory Chinese Academy of SciencesShanghai 200030China Xin.ian. Astron.mical Observatory Chinese Academy of SciencesUrumqi 830011China Key Laboratory of Radio Astron.my Chinese Academy of SciencesNanjing 210008China In.titute of Astron.my The University of Tokyo2-21-1 OsawaMitakaTokyo 181-0015Japan In.tituto de Astrofísica de An.alucía-CSIC Glorieta de la Astronomia s/nGranada E-18008Spain Departmen. of Physics Faculty of ScienceUniversity of MalayaKuala Lumpur 50603Malaysia Cen.er for Astron.my Ibaraki University2-1-1 BunkyoMitoIbaraki 310-8512Japan Space Light Laboratory 77Yangjaedae-ro 86 roadGangdong-guSeoulKorea Massachusetts In.titute of Techn.logy Haystack Observatory 99 Millstone RoadWestfordMA 01886USA n.tion.l Radio Astron.my Observatory 520 Edgemont RdCharlottesvilleVA 22903USA Toyo Un.versity 5-28-20 HakusanBunkyo-kuTokyo 112-8606Japan Departmen. of Physics an. Astron.my Seoul National UniversityGwanak-guSeoul 08826Korea Max Plan.k In.titute for Radio Astron.my Auf dem hiigel 69Bonn 53121Germany Sn. Astron.my Research Cen.er Seoul National UniversityGwanak-guSeoul 08826Korea

The East Asian.Very Lon. Baselin. In.erferometry(VLBI) n.twork(EAVn. is a rapidly evolvin. in.ern.tion.l VLBI array that is curren.ly promoted un.er join. efforts amon. Chin.,Japan.an. *** aims at formin. a join. VLBI n.twork by combin.n. a large n.mber of radio telescopes distributed over East Asian.*** the combin.tion.of the Korean.VLBI n.twork(KVn. an. the VLBI Exploration.of Radio Astrometry(VERA) in.o Ka VA,further expan.ion.with the join. array in.East Asia is actively *** we report the first imagin. results(at 22 an. 43 GHz) of bright radio sources obtain.d with Ka VA con.ected to Tian.a 65-m an. n.n.han.26-m Radio Telescopes in.*** test the EAVn.imagin. performan.e for differen. sources,we observed four active galactic n.clei(AGn. havin. differen. brightn.ss an. *** a result,we con.irmed that the Tian.a 65-m Radio Telescope(TMRT) sign.fican.ly en.an.es the overall array sen.itivity,a factor of 4 improvemen. in.baselin. sen.itivity an. 2 in.image dyn.mic ran.e compared to the case of Ka VA *** addition.of the n.n.han.26-m Radio Telescope(n.RT) further doubled the east-west an.ular *** the resultin. high-dyn.mic-ran.e,high-resolution.images with EAVn.Ka VA+TMRT+n.RT),various fin.-scale structures in.our targets,such as the coun.er-jet in.M87,a kin.-like morphology of the 3 C 273 jet an. the weak emission.in.other sources are successfully *** demon.trates the powerful capability of EAVn.to study AGn.jets an. to achieve other scien.e goals in.*** expan.ion.of EAVn.will further en.an.e the an.ular resolution.detection.sen.itivity an. frequen.y coverage of the n.twork.

关键词： galaxies:active galaxies:jets in.trumen.ation.in.erferometers radio con.in.um:galaxies

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急性卒中影像学研究路径图Ⅱ

国际脑血管病杂志 2014年第2期22卷 81-92页

作者： Max Win.ermark Gregory W. Albers Joseph P. Broderick An.rew M. Demchuk Jochen.B. Fiebach Jen. Fiehler James C. Grotta Gary Houser Tudor G. Jovin.Ken.edy R. Lees Michael H. Lev David S. Liebeskin. Marie Luby Keith W. Muir Mark W. Parson. Rudiger von.Kummer Joan.a M. Wardlaw On. Wu Albert J. Yoo An.rei V. Alexan.rov Jeffry R. Alger Richard I. Aviv Rolan. Bammer Jean.Claude Baron.Fern.n.o Calaman.e Bruce C.V. Campbell Trevor C. Carpen.er Sφren.Christen.en.William A. Copen.Colin.P. Derdeyn.E. Clarke Haley Jr Pooja Khatri Kohsuke Kudo Maarten.G. Lan.berg Lawren.e L. Latour Tin.-Yim Lee Richard Leigh Weili Lin.Patrick Lyden.Gran. Mair Bijoy IC Men.n.Patrik Michel Robert Mikulik Raul G. n.gueira Left φstergaard Salvador Pedraza Christian.H. Riedel Howard A. Rowley Pin. C. San.lli Makoto Sasaki jeffrey L. Saver Pamela W. Schaefer Peter D. Schellin.er Georgios Tsivgoulis Lawren.e R. Wechsler Philip M. White Greg Zaharchuk Osama O. Zaidat Stephen.M. Davis Geoffrey A. Don.an.An.hon. J. Furlan.Wern.r Hacke Don.-Wha Kan. Chelsea Kidw ell Vin.en. n. Thijs Gotz Thomalla Steven.J. Warach 严晓铭刘牧张晶晶柯开富不详南通大学附属医院神经内科 226001

卒中影像学研究组（StrokeImagin.ResearchGroup，STIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（Stro... 详细信息

卒中影像学研究组（StrokeImagin.ResearchGroup，STIR）、美国神经放射学学会和美国神经放射学学会基金会在过去1年多的时间时举办了一系列的工作会议，最后一次会议于2013年3月9日至10日在华盛顿召开的卒中治疗专业学术圆桌会议（Stroke Treatmen. Academy In.ustry Roun.table，STAIR）期间举行。

关键词：急性卒中影像学神经放射学路径会议基金会学会美国

Ven.ilation.practices in.burn.patien.s—an.in.ern.tion.l prospective observation.l cohort study

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Burn. & Trauma 2021年第1期9卷 47-57页

作者： Gerie J.Glas Jan.eke Horn.Markus W.Hollman. Ben.dikt Preckel Kirsten.Colpaert Man. Malbrain.Ary Serpa n.to Karim Asehn.un. Marcello Gamma de Abreu Ign.cio Martin.Loeches Paolo Pelosi Folke Sjoerg Jan.M.Bin.ekade Berry Cleffken.n.cole P.Jufferman. Paul Kn.pe Bert G.Loef David P.Mackie Peren.ei En.hbaatar n.dia Depetris An.ers Pern.r Eva Herrero Lucia Cachafeiro Marc Jeschke jeffrey Lipman.Matthieu Legran. Johan.es Horter Athin. Lavren.ieva Alex Kazemi An.e Berit Guttormsen.Frederik Huss Mark Kol Helen.Won. Therese Starr Luc De Crop Wilson.de Oliveira Filho Joa Man.el Silva Jun.or Cin.ia M.C.Grion.Marjorie Burn.tt Frederik Mon.rup Fran.ois Ravat Mathieu Fon.ain. Ren.n.Le Floch Mathieu Jean.e Morgan. Bacus Maite Chaussard Marcus Lehn.ardt Bassem Dan.el Mikhail Jochen.Gille Aidan.Sharkey n.cole Trommel Auke C.Reidin.a n.din. Vieleers An.a Tilsley Hen.in. On.rheim Maria Teresa Bouza Alexan.er Agrifoglio Filip Fredén.Tin. Palmieri Lyn.a E.Pain.in. Marcus J.Schultz LAMin.R in.estigators Academic Medical Cen.er University of AmsterdamAmsterdamAZ 1105The Netherlands Departmen. of An.esthesia an. In.en.ive Therapy Medical Un.versity of Lublin.Aleje Racklawickie 1–20-059 Lublin.Polan. AZ JAn.PALFIJn.GEn. Watersportlaan.5–9000 Gen.–Belgium ABC Medical School SaPauloBangúSP 5001Brazil Service d’An.sthésie Réan.mation.Chirurgicale Nantes 44093France Un.versity Hospital Carl Gustav Carus Dresden 01307Germany St James Un.versity Hospital Dublin D08 NHY1Ireland Un.versity of Gen.a GenoaGE 16128Italy Lin.oin. Un.versity Hospital Linkoing 58185Sweden Maasstad Hospital RotterdamDZ 3079The Netherlands Red Cross Hospital BeverwijkLE 1942The Netherlands Martin. Hospital GroningenNT 9728The Netherlands Un.versity of Texas Medical Bran.h GalvestonTX 77555USA Turin.CTO Burn.Cen.er TurinTO 10126Italy Rigshospitalet Copenhagen 2100Denmark La Paz Un.versity Hospital Madrid 28046Spain Ross Tilley Burn.Cen.re Sunnybrook Health Sciences CentreToronto M4N 3M5Canada Royal Brisban. an. Women.s Hospital Queensland UniversityHerstonQLD 4029Australia Australian.an. n.w Zealan. In.en.ive Care Research Cen.re.Mon.sh Un.versity MelbourneVIC 3004Australia GH St-Louis-Lariboisière APHPParis 75010France BG Klin.k Ludwigshafen Ludwigshafen 67071Germany Papan.koalou Hospital Thessaloniki 54621Greece Middlemore Hospital OtahuhuAuckland 2025New Zealand Haukelan. Un.versity Hospital Bergen 5021Norway Uppsala Un.versity Hospital Uppsala 75185Sweden Con.ord Repatriation.Gen.ral Hospital n.W University of SydneyConcord 2139Australia Zieken.uis n.twerk An.werpen.Stuiven.erg Antwerpen 2060Belgium Un.versidade de Sao Paulo Sao Paulo 01246-903Brazil Un.versidade Estadual de Lon.rin. Londrina 86057-970Brazil Sun.ybrook Health Scien.es Cen.re Toronto M4N 3M5Canada CHU Lyon.St Luc Lyon 69007France CHU n.n.es Service dán.sthesie rean.mation.chirugicale Nantes 44093France Hopital Roger Salen.ro CHRU LilleLille 59037France Sain.-Louis Hospital Paris 75010France BG Un.versity Hospital Bergman.sheil Bo

Backgroun.:It is un.n.wn.whether lun.-protective ven.ilation.is applied in.burn.patien.s an. whether they ben.fit from *** study aimed to determin. ven.ilation.practices in.burn.in.en.ive care un.ts(ICUs)an. in.estigate the association.between.lun.-protective ven.ilation.an. the n.mber of ven.ilator-free days an. alive at day 28(VFD-28).Methods:This is an.in.ern.tion.l prospective observation.l cohort study in.ludin. adult burn.patien.s requirin. mechan.cal *** tidal volume(V_(T))was defin.d as V_(T)≤8 mL/kg predicted body weight(PBW).Levels of positive en.-expiratory pressure(PEEP)an. maximum airway pressures were *** association.between.V_(T) an. VFD-28 was an.lyzed usin. a competin. risk *** settin.s were presen.ed for all patien.s,focusin. on.the first day of *** also compared ven.ilation.settin.s between.patien.s with an. without in.alation.***:A total of 160 patien.s from 28 ICUs in.16 coun.ries were *** V_(T) was used in.74%of patien.s,median.V_(T) size was 7.3[in.erquartile ran.e(IQR)6.2–8.3]mL/kg PBW an. did n.t differ between.patien.s with an. without in.alation.trauma(p=0.58).Median.VFD-28 was 17(IQR 0–26),without a differen.e between.ven.ilation.with low or high V_(T)(p=0.98).All patien.s were ven.ilated with PEEP levels≥5 cmH_(2)O;80%of patien.s had maximum airway pressuresn.this in.ern.tion.l cohort study we foun. that lun.-protective ven.ilation.is used in.the majority of burn.patien.s,irrespective of the presen.e of in.alation.*** of low V_(T) was n.t associated with a reduction.in.*** registration.*** *** of registration.9 December 2014.

关键词： Mechan.cal ven.ilation In.alation.trauma Lun.-protective Critical care

An.eceden.s an. sex/gen.er differen.es in.youth suicidal behavior

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World Journ.l of Psychiatry 2014年第4期4卷 120-132页

作者： An.e E Rhodes Michael H Boyle jeffrey A Bridge Mark Sin.or Paul S Lin.s Lil Ton.yr Robin.Skin.er Jen.ifer M Bethell Corin. Carlisle Sarah Goodday Travis Salway Hottes Aman.a n.wton.Kathryn.Ben.ett Purn.ma Sun.ar Amy H Cheun. Peter Szatmari In.titute for Clin.cal Evaluative Scien.es Toronto M4N 3M5 Ontario Canada Departmen. of Psychiatry University of Toronto Toronto M5T 1R8 Ontario Canada Suicide Studies Un.t St. Michael’s Hospital Toronto M5B 1W8 Ontario Canada Dalla Lan. School of Public Health University of Toronto Toronto M5T 3M7 Ontario Canada Departmen. of Psychiatry an. Behavioural n.uroscien.es Mc Master University Hamilton L8N 3K7 Ontario Canada The Offord Cen.re for Child Studies Hamilton L8S 4K1 Ontario Canada The Research In.titute at n.tion.ide Children.s Hospital Columbus OH 43205 United States The Ohio State Un.versity College of Medicin. Columbus OH 43210 United States Sun.ybrook Health Scien.es Cen.re Toronto M4N 3M5 Ontario Canada Departmen. of Psychiatry University of Western Ontario London N6A 5W9 Ontario Canada The In.ury an. Child Maltreatmen. Section Public Health Agency of Canada Ottawa K1A 0K9 Ontario Canada The Cen.re for Addiction.an. Men.al Health Toronto M6J 1H4 Ontario Canada Departmen. of Pediatrics University of Alberta Edmonton Alberta T6G 1C9 Canada The Departmen. of Clin.cal Epidemiology an. Biostatistics Mc Master University Hamilton L8S 4K1 Ontario Canada The On.ario Cen.re of Excellen.e for Child an. Youth Men.al Health Ottawa K1G 0Z1 Ontario Canada The Hospital for Sick Children Toronto M5G 1X8 Ontario Canada

Suicide is the secon. leadin. cause of death in.youth globally; however, there is un.ertain.y about how best to in.erven.. Suicide rates are typically higher in.males than.females, while the con.erse is true for suicide attempts. We review this "gen.er paradox" in.youth, an. in.particular, the age-depen.en.y of these sex/gen.er differen.es an. the developmen.al mechan.sms that may explain.them. Epidemiologic, gen.tic,n.urodevelopmen.al an. psychopathological research have iden.ified suicidal behaviour risks arisin. from gen.tic vuln.rabilities an. sex/gen.er differen.es in.early adverse en.iron.en.s, n.urodevelopmen., men.al disorder an. their complex in.ercon.ection.. Further, evolvin. sex-/gen.er-defin.d social expectation. an. n.rms have been.thought to in.luen.e suicide risk. In.particular, how youth perceive an. cope with threats an. losses(in.ludin. con.ormin. to others' or on.'s own.expectation. of sex/gen.er iden.ity) an. adapt to pain.through substan.e use an. helpseekin. behaviours). Taken.together, con.iderin. brain.plasticity over the lifespan. these proposed an.eceden.s to youth suicide highlight the importan.e of in.erven.ion. that alter early en.iron.en.(s)(e.g., childhood maltreatmen.) an./or on.'s ability to adapt to them. Further, such in.erven.ion. may have more en.urin. protective effects, for the in.ividual an. for future gen.ration., if implemen.ed in.youth.

关键词： Suicide Attempted suicide Sex Gen.er Child Adolescen. Review

卒中医疗体系内部的相互交流美国心脏协会／美国卒中协会的政策声明

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国际脑血管病杂志 2014年第8期22卷 561-582页

作者：李海峰赵翠萍粱兵赵冰张永庆李玲徐军山东大学齐鲁医院(青岛)神经内科 266071

卒中医疗体系内部的相互交流美国心脏协会／美国卒中协会的政策声明在美国和世界各地，很多城市、州和地区正在建立针对急性卒中患者的多层次医疗体系。这些体系通常包括由各种规章和制度支持的一系列医疗卫生组成部分。本政策声明将为... 详细信息

卒中医疗体系内部的相互交流美国心脏协会／美国卒中协会的政策声明在美国和世界各地，很多城市、州和地区正在建立针对急性卒中患者的多层次医疗体系。这些体系通常包括由各种规章和制度支持的一系列医疗卫生组成部分。本政策声明将为卒中医疗体系提出旨在优化患者诊治和管理以及改善患者转归、切实可行且由现有临床资料或专家共识支持的概念和要素。我们还将对卒中医疗体系的关键要素提出政策推荐。

关键词：美国心脏协会卒中协会医疗体系急性卒中医疗卫生临床资料多层次患者