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Adenosine:An immune modulator of inflammatory bowel diseases

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World Journal of Gastroenterology 2009年第36期15卷 4491-4498页

作者： jeff.Huaqing Ye Vazhaikkurichi M Rajendran Digestive Health Center and Southern Tennessee Internal Medicine WinchesterTN 37398United States Department of Biochemistry and Microbiology West Virginia University School of Medicine MorgantownWV 26506United States

Inflammatory bowel disease(IBD)is a common and lifelong disabling gastrointestinal *** treatments are being developed to target inflammatory cytokines which initiate and perpetuate the immune *** is an important modulator of inflammation and its anti-inflammatory effects have been well established in humans as well as in animal *** extracellular adenosine suppresses and resolves chronic inflammation in IBD *** extracellular adenosine levels could be achieved by enhanced adenosine absorption and increased de novo *** adenosine concentration leads to activation of the A2a receptor on the cell surface of immune and epithelial cells that would be a potential therapeutic target for chronic intestinal inflammation. Adenosine is transported via concentrative nucleoside transporter and equilibrative nucleoside transporter transporters that are localized in apical and basolateral membranes of intestinal epithelial cells,respectively. Increased extracellular adenosine levels activate the A2a receptor,which would reduce cytokines responsible for chronic inflammation.

关键词： Crohn's disease Ulcerative colitis Inflammatory bowel diseases Epithelial cells Membranetransporters Immuno-modulator

Robust Optimization of the Output Voltage of Nanogenerators by Statistical Design of Experiments

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Nano Research 2010年第9期3卷 613-619页

作者： Jinhui Song Huizhi Xie Wenzhuo Wu V.Roshan Joseph C.F.jeff.Wu Zhong Lin Wang School of Materials Science and Engineering Georgia Institute of TechnologyAtlantaGeorgia 30332-0205USA School of Industrial and Systems Engineering Georgia Institute of TechnologyAtlantaGeorgia 30332-0205USA

Nanogenerators were first demonstrated by deflecting aligned ZnO nanowires using a conductive atomic force microscopy(AFM)*** output of a nanogenerator is affected by three parameters:tip normal force,tip scanning speed,and tip *** this work,systematic experimental studies have been carried out to examine the combined effects of these three parameters on the output,using statistical design of experiments.A statistical model has been built to analyze the data and predict the optimal parameter *** an AFM tip of cone angle 70°coated with Pt,and ZnO nanowires with a diameter of 50 nm and lengths of 600 nm to 1μm,the optimized parameters for the nanogenerator were found to be a normal force of 137 nN and scanning speed of 40μm/s,rather than the conventional settings of 120 nN for the normal force and 30μm/s for the scanning speed.A nanogenerator with the optimized settings has three times the average output voltage of one with the conventional settings.

关键词： ZnO nanowire arrays robust parameter design nanogenerator piezoelectric properties

Knowledge extraction from Chinese wiki encyclopedias

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Journal of Zhejiang University-Science C(Computers and Electronics) 2012年第4期13卷 268-280页

作者： Zhi-chun WANG Zhi-gang WANG Juan-zi LI jeff.Z.PAN Department of Computer Science and Technology Tsinghua UniversityBeijing 100084China Department of Computer Science University of AberdeenAberdeen AB243UEUK

The vision of the Semantic Web is to build a 'Web of data' that enables machines to understand the semantics of information on the *** Linked Open Data(LOD) project encourages people and organizations to publish various open data sets as Resource Description Framework(RDF) on the Web,which promotes the development of the Semantic *** various LOD datasets,DBpedia has proved a successful structured knowledge base,and has become the central interlinking-hub of the Web of data in ***,in the Chinese language,there is little linked data published and linked to *** hinders the structured knowledge sharing of both Chinese and cross-lingual *** paper deals with an approach for building a large-scale Chinese structured knowledge base from Chinese wiki resources,including Hudong and Baidu *** proposed approach first builds an ontology based on the wiki category system and infoboxes,and then extracts instances from wiki *** Hudong as our source,our approach builds an ontology containing 19 542 concepts and 2381 properties.802 593 instances are extracted and described using the concepts and properties in the extracted ontology and 62 679 of them are linked to equivalent instances in *** from Baidu Baike,our approach builds an ontology containing 299 concepts,37 object properties,and 5590 data type properties.1 319 703 instances are extracted from Baidu Baike,and 84 343 of them are linked to instances in *** provide RDF dumps and SPARQL endpoint to access the established Chinese knowledge *** knowledge bases built using our approach can be used not only in Chinese linked data building,but also in many useful applications of large-scale knowledge bases,such as question-answering and semantic search.

关键词： Semantic Web Linked Data Ontology Knowledge base

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Lessons in Giving

空中英语教室（高级版．彭蒙惠英语） 2010年第1期 31-33,46,47页

作者： jeff.Bailey

Living in China:Hold the Oil Please

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China's Foreign Trade 2011年第11期 92-93页

作者： jeff.Crowther Executive Director of U.S.-China Health Products Association

After residing in Beijing for over 6 years, many of my friends and colleagues in the d3.S. have said, Wow, it must be amazing living in China＂. Over the years I have to say, my experiences have been amazing. The one thing that keeps life interesting is that each and everyday I learn or experience something new. Today it might be a new word or expres- sion in Chinese, the next day I might see a group of senior citizens dancing to disco music in my community and when I really want to experience local Beijing style, I head into Beijing＇s hutong neigh- borhoods. T

关键词：生活中国北京音乐

Quality,Safety and Consistency Equals Better Business

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China's Foreign Trade 2012年第5期 44-45页

作者： jeff.Crowther Executive President of U.S.-China Health Products Asso-ciation

The United States and China oth hold unique titles in the obal dietary supplement inustry. The *** the global leader in regard to manufacturing and marketing finished dietary supplements and China is the largest suppl... 详细信息

关键词：安全性一致性膳食补充剂质量商业领导者供应商中国

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NEWS WORTHY CLIPS

空中英语教室（高级版．彭蒙惠英语） 2024年第9期 12-14,41,42页

作者： jeff.Haden 不详

Considerable research shows coffee can dramatically affect how your body and brain work.A study in Circulation found coffee can reduce the risk of stroke by 20%.Another study shows coffee can reduce your risk of cance... 详细信息

关键词： CLIPS diabetes NEWS

Cell based in vitro toxicity testing

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Cell based in vitro toxicity testing

China's Developing Dietary Supplement Industry

中国毒理学会第六届全国毒理学大会

作者： jeff.HASKINS

＜正＞The use of cells and fluorescent probes have emerged as mainstream in vitro toxicology tools where fluorescence imaging is applied and image analysis extracts quantitative features that describe cell health and cell *** presentation will detail the application of fluorescence imaging for the study of drug and chemical-induced liver injury,genetic toxicity,reproductive toxicity,neurotoxicity, and acute toxicity associated with carbon ***,fluorescence biosensors,data analy- ses,and data reduction are key components of this technology designed to predict toxic affects in human following exposure to drug or *** presentation will be a comprehensive technology review.

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China's Foreign Trade 2011年第6期 43-45页

作者： jeff.Crowther CEO/Executive Director of U.S.- China Health Products Association

With the increasingly large size and forward momentum of China's economy,one would think there has to be a well-developed dietary supplement ***, although China has been posting record gains to its GDP,it is far behind the U.S.,*** Japan in regard to a well-defined and prosperous dietary supplement *** that said, having an established dietary supplement industry is not the measure by which countries are judged in terms of economic ***,having one does reflect a larger percentage of consumers with expendable income seeking a healthier life,which China is in the process of *** positive sign of China's consumer growth was the recently released consumer spending indicators for March 2011

关键词：膳食补充剂发展中国家行业国内生产总值中国经济经济实力