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Enhancement of magnetic properties of hot pressed/die-upset Dy-free Nd-Fe-B magnets with Cu/Nd coating by wet process

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Rare Metals 2020年第1期39卷 48-54页

作者： jeehye kwon Dajeong Lee Dayoung Yoo Seongkyu Park Hee-Ryoung Cha Hae-Woong kwon Junggoo Lee Dongyun Lee Department of Advanced Circuit Interconnection Pusan National UniversityBusan46241Republic of Korea Department of Nano Fusion Technology Pusan National UniversityBusan46241Republic of Korea Powder and Ceramics Department Korea Institute of Machinery and MaterialsChangwon51508Republic of Korea Department of Materials Science and Engineering Pukyong National UniversityBusan48513Republic of Korea Department of Nanoenergy Engineering Pusan National UniversityBusan46241Republic of Korea

A grain boundary diffusion process(GBDP)was adopted to improve magnetic properties of Dy-free highly coercive Nd-Fe-B permanent magnet by coating thin layers of Nd and Cu in grain *** GBDP of Nd and Cu,Nd and Cu were coated by wet process,e.g.,electrochemical and electroless on Nd-Fe-B magnets,which was fabricated by hot-deformed/die-upset with meltspun *** treatment was performed for 20 min at 600℃followed by several different cooling *** cooling conditions after heat treatment were varied to understand distribution and micros tructural effects of Nd and Cu species in grain *** coercivity increased from 1.565 to 1.637 T in oil cooling rate but remanence decreased,while remanence jumped with little decrease in coercivity in furnace *** tructure analyses suggested that the coercivity was closely related to the cooling rate as well as distribution of *** mechanism of coercivity enhancement due to the cooling rate was discussed based on the results presented here and those in the literature.

关键词： Magnetic materials Electrochemical deposition Diffusion Scanning electron microscopy Coercivity

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Different oncological features of colorectal cancer codon-specific KRAS mutations:Not codon 13 but codon 12 have prognostic value

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World Journal of Gastroenterology 2023年第32期29卷 4883-4899页

作者： Hong-Min Ahn Duck-Woo Kim Tae Gyun Lee Hye-Rim Shin In Jun Yang jeehye Lee Jung Wook Suh Heung-kwon Oh Sung-Bum Kang Department of Surgery Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Pathology Seoul National University Bundang HospitalSeongnam 13620South Korea Department of Pathology Seoul National University HospitalSeoul 03080South Korea

BACKGROUND Approximately 40%of colorectal cancer(CRC)cases are linked to Kirsten rat sarcoma viral oncogene homolog(KRAS)*** mutations are associated with poor CRC prognosis,especially KRAS codon 12 mutation,which is associated with metastasis and poorer ***,the clinicopathological characteristics and prognosis of KRAS codon 13 mutation in CRC remain *** To evaluate the clinicopathological characteristics and prognostic value of codonspecific KRAS mutations,especially in codon *** This retrospective,single-center,observational cohort study included patients who underwent surgery for stage I-III CRC between January 2009 and December *** with KRAS mutation status confirmed by molecular pathology reports were *** relationships between clinicopathological characteristics and individual codon-specific KRAS mutations were *** data were analyzed to identify codon-specific KRAS mutations as recurrence-related factors using the Cox proportional hazards regression *** Among the 2203 patients,the incidence of KRAS codons 12,13,and 61 mutations was 27.7%,9.1%,and 1.3%,*** KARS codons 12 and 13 mutations showed a tendency to be associated with clinical characteristics,but only codon 12 was associated with pathological features,such as stage of primary tumor(T stage),lymph node involvement(N stage),vascular invasion,perineural invasion,tumor size,and microsatellite *** codon 13 mutation showed no associations(77.2%vs 85.3%,P=0.159),whereas codon 12 was associated with a lower 5-year recurrence-free survival rate(78.9%vs 75.5%,P=0.025).In multivariable analysis,along with T and N stages and vascular and perineural invasion,only codon 12(hazard ratio:1.399;95%confidence interval:1.034-1.894;P=0.030)among KRAS mutations was an independent risk factor for *** This study provides evidence that KRAS codon 13 mutation is less likely to serve as a prognostic biom

关键词： Genes Ras Codon Colonic neoplasms Rectal neoplasms

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