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Extraction and clipping repair of a chicken bone penetrating the gastric wall

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World Journal of Gastroenterology 2008年第12期14卷 1955-1957页

作者： Jin-Soo Kim Hyung-Keun Kim Young-Seok Cho Hiun-suk Chae chang-Whan Kim Byung-Wook Kim Sok-Won Han Kyu-Yong Choi Department of Internal Medicine College of Medicine The Catholic University of Korea Uijeongbu St. Mary's Hospital Gyeonggi-do 480-717 Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Holy Family Hospital Gyeonggi-do 420-717 Korea Department of Internal Medicine College of Medicine The Catholic University of Korea Our lady of Mercy Hospital Gyeonggi-do 420-717 Korea

We report a case of gastric penetration caused by accidental ingestion of a chicken bone in a 42-year old woman with a partially wearing denture. Three days ago, she accidentally swallowed several lumps of poorly-chewed chicken. Physical examination disclosed mild tenderness in the periumbilical area. Abdominal Computed tomography (CT) showed a suspicious penetration or perforation of the stomach wall measuring about 3 cm, by a linear radiopaque material at the lesser curvature of the antrum. The end of a chicken bone was very close to but did not penetrate the liver. Endoscopic examination revealed a chicken bone that penetrated into the prepyloric antrum. The penetrating chicken bone was removed with grasping forceps. Five endoscopic clips were applied immediately at the removal site and the periumbilical pain resolved promptly. After removal of the chicken bone, the patient was treated with conservative care for three days, after which she was completely asymptomatic and discharged without complication. To treat gastric penetration by a foreign body, endoclipping can be a useful method in patients with no signs or symptoms of peritoneal irritation.

关键词：胃穿孔鸡骨头异物治疗方法

Overexpression of S100A4 is closely associated with progression of colorectal cancer

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World Journal of Gastroenterology 2005年第31期11卷 4852-4856页

作者： Yong-Gu Cho chang-Jae Kim suk-Woo Nam Shin-Hee Yoon Sug-Hyung Lee Nam-Jin Yoo Jung-Young Lee Won-Sang Park Department of Pathology Department of Physiology

AIM: To investigate whether S100A4 played an important role in the development or progression of colorectal ***: A total of 124 colorectal adenocarcinoma tissue specimens were analyzed by immunohistochemistry for the expression of S100A4 protein and subsequently investigated for the gene mutations in the coding region of S100A4 gene. The specimens were collected over a 3-year period in the laboratories at our large teaching hospital in Seoul, Republic of ***: Normal colonic epithelium either failed to express or showed focal weak expression of S100A4. Moderate to strong cytoplasmic expression of S100A4 was seen in 69(55.6%) of the 124 colorectal carcinoma tissue specimens.S100A4 expression was detected in 43 (69.4%) of 62specimens with lymph node metastasis. Statistically,overexpression of S100A4 was significantly associated with Dukes' stage and lymph node metastasis. Nuclear staining was also observed in 24 (19.4%) of 124 samples and closely associated with Dukes' stage. However, there was no significant correlation between overexpression of S100A4and other investigated clinico-pathologic parameters,including tumor localization, tumor size, and survival *** mutational analysis, no gene mutation was found in the analyzed genomic area of colorectal ***: Overexpression of 5100A4 may be closely related with the aggressiveness of colorectal carcinoma.

关键词： S100A4 基因表达结直肠癌病理机制

Xanthoma disseminatum with intracranial involvement

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Xanthoma disseminatum with intracranial involvement

The Second Eastern Asia Dermatology Congress(EADC2012)

作者： Tai Kyung Noh Hye Rim Moon Chong Hyun Won Sung Eun chang Mi Woo Lee jee Ho Choi Kee Chan Moon Department of Dermatology Asan Medical CenterUniversity of Ulsan College of MedicineSeoulKorea

＜正＞Xanthoma disseminatum（XD） is a rare normolipidemic mucocutaneous xanthomatosis classified as a benign non-Langerhans cell *** is characterized by mucocutaneous xanthomas symmetrically distributed,typically inv...

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Comparison of double pants with single pants on satisfaction with colonoscopy

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World Journal of Gastroenterology 2013年第26期19卷 4177-4184页

作者： Sook Hee Chung Soo Jung Park Jong suk Hong jee Young Hwang Sin Ae Lee Kyung Ran Kim Hye Sun Lee Sung Pil Hong Jae Hee Cheon Tae Il Kim Won Ho Kim Department of Internal Medicine and Institute of Gastroenterology Yonsei University College of Medicine Department of Psychiatry Yonsei University College of Medicine Department of Biostatistics Yonsei University College of Medicine

AIM: To increase satisfaction and diminish anxiety and shame during colonoscopy, we developed novel double pants (NDP) which consist of doubled fabrics with an inner hole. The aim of study was to compare satisfaction, anxiety and shame between NDP and conventional single pants (CSP). METHODS: Total 160 consecutive examinees were randomly divided into NDP and CSP group. Before colonoscopy, questionnaires identifying state and trait anxiety were completed. After colonoscopy, questionnaires for overall satisfaction (Group Health Association of America 9) and pants-specific satisfaction (5-20), state anxiety (20-80), and shame (6-24) were interviewed. RESULTS: Pants-specific satisfaction scores regarding willingness to repeat colonoscopy using same pants (3.3 ± 0.8 vs 2.1 ± 0.9, P < 0.001) and recommendation of same pants to other people (3.3 ± 0.7 vs 2.0 ± 1.0, P < 0.001) were significantly higher in NDP than CSP groups. State anxiety (33.0 ± 7.0 vs 35.4 ± 6.9, P = 0.028) and shame (6.6 ± 1.5 vs 8.1 ± 3.2, P = 0.001) after colonoscopy was lower in NDP group compared with CSP group. CONCLUSION: The NDP contribute to increase satisfaction and decrease anxiety and shame after colonoscopy.

关键词： Pants Colonoscopy Satisfaction Shame Anxiety

Determination of Rutin Using Lucigenin as Chemiluminogenic Reagent

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Determination of Rutin Using Lucigenin as Chemiluminogenic R...

The 3rd Asian and Oceanian Conference on Photobiology

作者： Seung Oh Jin Kyoung Hye Choi Yeoun suk Suh Sang Hak Lee Jong Ha Choi chang Jin Kim Department of Chemistry Kyungpook National UniversityTaegu702-701Korea Department of Chemistry Kyungpook National UniversityTaegu702-701Korea Department of Chemistry Kyungpook National UniversityTaegu702-701Korea Department of Chemistry Kyungpook National UniversityTaegu702-701Korea Department of Chemistry Andong National UniversityAndong760-749Korea Department of Chemistry Daegu University Taegu 705-033 Korea

＜正＞Rutin, a flavanoid glucoside known as vitamin P, is an oral capillary preservatory drug, usually used for the therapy of chronic venous insufficiency. An inhibitory effect of rutin on the chemiluminescence （CL） reaction between lucigenin and hydrogen peroxide was reported, and this effect was used for the determination of rutin in medicine. The CL signal produced by the reaction between lucigenin and H2O2, was decreased in the presence of rutin. Rutin was sensed by measuring the decrement of CL intensity, and which was observed to be linear over 1×10-6M - 1×10-4M rutin concentration range, and the limit of detection was 2.5×10-7M. The concentrations of lucigenin, H2O2, NaOH and flow rate of the manifold were all optimized. The method proposed was applied successfully in the determination of rutin in pharmaceutical preparations .

关键词： Rutin Lucigenin Chemiluminescence

Neuroprotective effects of Lycium barbarum polysaccharides on acute ischemic stroke injury

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Neuroprotective effects of Lycium barbarum polysaccharides o...

中国神经科学学会第四次会员代表大会暨第八届全国学术会议

作者： Amy Cheuk-Yin LO Chung-Man YEUNG suk-Yee LI Raymond Chuen-Chung chang Kwok-Fai SO David WONG Eye Institute Li Ka Shing Faculty of MedicineThe University of Hong Kong Research Center of Heart BrainHormone and Healthy AgingLi Ka Shing Faculty of MedicineThe University of Hong Kong Department of Anatomy Li Ka Shing Faculty of MedicineThe University of Hong Kong St Paul’s Eye Unit University of LiverpoolUK

＜正＞Objective The polysaccharides in Lycium barbarum,a well known traditional Chinese medicine,have been demonstrated to display multiple biological effects such as anti-aging,anti-tumor and *** the present study,we aimed to evaluate the effects of Lycium barbarum polysaccharides（LBP） on murine brain injury after induction of acute ischemic stroke by middle cerebral artery occlusion（MCAO）.Methods Mice were orally treated with either vehicle（PBS） or LBP（1 mg/kg or 10 mg/kg） for 1 week before induction of cerebral ischemia by *** 2 h of ischemia followed by 22 h of reperfusion,animals were evaluated for neurological *** after scoring of the neurological deficits,brains were isolated,cut into 6 coronal slices of 2 mm thickness and stained with 2%2,3,5-triphenyltetrazolium chloride（TTC） to detect lesion *** posterior surface of each brain slice was subsequently photographed and analyzed using a digital image analysis *** area,volume,and hemispheric brain swelling were calculated using an indirect method in which the effects of edema and brain swelling have been ***（1） Mice treated with either 1 mg/kg LBP or 10 mg/kg LBP（n=7 for each group） had less neurological deficits than the vehicle-treated mice（n=8）（vehicle=2.0+/-0.3,1 mg/kg LBP=1.4+/-0.2,10 mg/kg LBP=1.1+/-0.1）.（2） TTC staining revealed a significantly smaller infarct area in brain slice number 4 in the LBP-treated mice when compared with the vehicle-treated mice（vehicle=35.4+/- 4.2%,1 mg/kg LBP=17.5+/-5.8%,10 mg/kg LBP=17.6+/-4.9%）.（3） Consistent with the infarct area data,the overall infarct volumes were decreased in the LBP-treated groups（vehicle=25.8+/-3.1%,1 mg/kg LBP=215+/-2.5%,10mg/kg LBP=16.6+/-2.7%）. （4） Mice treated with LBP displayed less hemispheric brain swelling（vehicle=11.1+/-0.9%,1 mg/kg LBP=9.7+/-1.1%,10mg/kg LBP=7.9+/-0.6%）.Conclusions Taken together,these data indicate that treatment with LBP for 1 week could protect the mouse

关键词： neuroprotection animal model oxidative stress

Neuronal damage and blood-retinal barrier disruption in retinal ischemia/reperfusion injury:protective effects of Lycium barbarum polysaccharides

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Neuronal damage and blood-retinal barrier disruption in reti...

中国神经科学学会第九届全国学术会议暨第五次会员代表大会

作者： Amy Cheuk Yin Lo suk-Yee Li Chung-Man Yeung Raymond Chuen-Chung chang Kwok-Fai So David Wong Eye Institute Li Ka Shing Faculty of MedicineThe University of Hong Kong Research Center of Heart BrainHormone and Healthy AgingLi Ka Shing Faculty of MedicineThe University of Hong Kong Department of Anatomy Li Ka Shing Faculty of MedicineThe University of Hong Kong

＜正＞Objective Neuronal cell death,glial cell activation,retinal swelling and oxidative injury are complications in retinal ischemia/reperfusion（I/R） *** barbarum polysaccharides（LBP）,extracts from the wolfberries, are good for "eye health" in Chinese *** aim of our present study is to explore the use of LBP in retinal I/R *** Retinal I/R injury was induced by surgical occlusion of the internal carotid *** to induction of ischemia,mice were fed orally with either vehicle（PBS） or LBP（1 mg/kg） once a day for 1 week. Ischemia was maintained for 2 hours and reperfusion was then allowed for 22 ***-embedded retinal sections were *** cells were counted while apoptosis was assessed using TUNEL *** levels of glial fibrillary acidic protein（GFAP）,aquaporin-4（AQP4）,poly（ADP-ribose）（PAR） and nitrotyrosine （NT） were investigated by *** integrity of blood-retinal barrier（BRB） was examined by IgG extravasation *** Decreased viable cell count and apoptosis were found in the ganglion cell layer （GCL） and the inner nuclear layer（INL） of the vehicle-treated I/R ***,increased retinal thickness, GFAP activation,AQP4 up-regulation,IgG extravasation and PAR expression level were observed in the vehicletreated I/R *** importantly,many of these changes were diminished or abolished in the LBP-treated I/R *** Pre-treatment with LBP for 1 week effectively protected the retina from neuronal death,apoptosis, glial cell activation,aquaporin water channel up-regulation,disruption of BRB and oxidative *** present study suggests that LBP may have a neuroprotective role in ocular diseases in which I/R is a feature.

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A case of ascending colon variceal bleeding treated with venous coil embolization

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World Journal of Gastroenterology 2013年第2期19卷 311-315页

作者： Bong suk Ko Woo Tae Kim Su Sun chang Eun Hye Kim Seung Woo Lee Won Seok Park Yeon Soo Kim Soon Woo Nam Dong Soo Lee Ji chang Kim Sang Bum Kang Department of Internal Medicine College of MedicineThe Catholic University of KoreaDaejeon St.Mary's HospitalDaejeon 301-723South Korea Department of Radiology College of MedicineThe Catholic University of KoreaDaejeon St.Mary's HospitalDaejeon 301-723South Korea

A 38-year-old female with a history of alcoholic liver cirrhosis visited our hospital with a massive *** esophagogastroduodenoscopy did not demonstrate any bleeding source,and a colonoscopy showed a massive hemorrhage in the ascending colon but without an obvious *** source of the bleeding could not be found with a mesenteric artery *** performed an enhanced abdominal computed tomography,which revealed a distal ascending colonic varix,and assumed that the varix was the source of the *** performed a venous coil embolization and histoacryl injection to obliterate the colon *** intervention appeared to be successful because the vital signs and hemoglobin laboratory data remained stable and because the hematochezia was no longer *** report here on a rare case of colonic variceal bleeding that was treated with venous coil embolization.

关键词： Colon ascending Varicose veins Liver cirrhosis Therapeutic embolization

Cerebral and pulmonary embolisms after transcatheter arterial chemoembolization for hepatocellular carcinoma

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World Journal of Gastroenterology 2008年第30期14卷 4834-4837页

作者： chang Soo Choi Ki Hoon Kim Geom Seog Seo Eun Young Cho Hyo Jeong Oh Suck Chei Choi Tae Hyeon Kim Haak Cheoul Kim Byung suk Roh Department of Internal Medicine and Digestive Disease Research Institute Wonkwang University School of Medicine Department of Radiology Wonkwang University School of Medicine

A cerebral lipiodol embolism is an extremely rare complication of transcatheter arterial chemoem bolization for hepatocellular carcinoma. We present a case of cerebral lipiodol embolism that occurred afte the third ar... 详细信息

关键词：肝细胞癌脑栓塞转导管动脉化学栓塞并发症