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Risk Factors for Geo-Helminthiasis in Children Aged 6 - 36 Months in a Rural Health District in Cameroon

Open Journal of Pediatrics 2024年第2期14卷 391-400页

作者： Isabelle Mekone Nkwele Monono Naiza Gervais Talla Kamga Hugues Nana Djeunga jeannette epée Ngoue Patricia epée eboumbou Suzanne Ngo Um Sap evelyn Mah Mungeh Joseph Kamgno Department of Pediatrics Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Department of Internal Medicine and Paediatrics Faculty of Health Sciences University of Buea Buea Cameroon Centre de Recherche sur les Filarioses et autres Maladies Tropicales (CRFilMT) Yaoundé Cameroon Department of Clinical Sciences Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Public Health Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon

Introduction and Objectives: Soil-Transmitted-Helminthiasis (STH) is a public health problem in Cameroon. The control strategies currently in place, particularly chemoprevention, has shortcomings linked to the target population, which are school-age children. The objective was to determine the prevalence and the risk factors associated with geo-helminthiasis in children aged 0 to 3 years in a rural health district. Method: From December 2020 to May 2021, a descriptive and analytical cross-sectional study of 376 children between 6 and 36 months was carried out in the Akonolinga health district. This was a cluster sampling in 4 health areas. Stool samples were collected and analysed using the mini-FLOTAC method. The results expressed as the number of eggs per gram of stool. A questionnaire on socio-demographic and lifestyle data was administered to the parents. The Chi-squared test was used to measure the association between geo-helminth infection and the data collected. A multivariate analysis using logistic regression was performed (p 0.05). Results: The prevalence of STH was 19.4% (Ascaris lumbricoides: 16% and Trichuris trichiura: 8%). Risk factors were: consumption of contaminated water (AOR = 1.93 [1.03 - 3.6];p = 0.040), early contact of the child with the ground (before age of 4 months) (AOR = 4.9 [2.1 - 11.37];p .001), habit of walking barefoot (AOR = 2.91 [1.1 - 7.97];p = 0.038), and living in a habitat with unpaved ground (AOR = 7.4 [1.55 - 35.7];p = 0.012). Conclusion: The prevalence of STHs in infants was high. Preventive chemotherapy should be extended to this age-group, and other measures intensified.

关键词： Akonolinga Soil-Transmitted-Helminths Children Aged 0 - 3 Years Risk Factors

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Diagnosis of CAH in a Sub Saharan Country: Visible Part of Iceberg

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Open Journal of Pediatrics 2024年第2期14卷 227-233页

作者： Suzanne Sap Ritha Mbono Hélène Kamo Jocelyn Tony Charlotte eposse jeannette epée Isabelle Mekone Adele Bodieu Gaelle Ntsoli Paul Olivier Koki Mother and Child Center of the Chantal Biya Foundation University of Yaoundé I Yaoundé Cameroon Laquintinie Hospital University of Douala Douala Cameroon Genral Hospital of Garoua University of Garoua Garoua Cameroon Human Reproductive Center and Research on Fertility of Yaoundé University of Yaoundé I Yaoundé Cameroon Yaounde General Hospital University of Yaoundé I Yaoundé Cameroon Yaounde Central Hospital Yaoundé Cameroon Laquintiinie Hospital Douala Cameroon

Introduction :Congenital adrenal hyperplasia (CAH) is the most common cause of primary adrenal insufficiency. It is a rare monogenic recessive disorder. In African setting in absence of neonatal screening, the diagnosis is still late, based on a clinical approach. During this clinical enquiry, information from past history or pedigree of the patient is of a huge importance and may revealed surprises. Patients and Methods: In this observational study, we retrospectively included all patients with a diagnosis of CAH. The diagnosis of CAH was retained based on a high 17 hydroxyprogesterone level in addition to clinical and morphological findings. From patients’ files, we extracted data on family history of disease, pedigree, clinical findings and genetics when available of 39 patients from two endocrinopeadiatric centers. Results: In 13 (30%) families, we found 20 reported deaths of infant less than 12 months. In these 13 families, half of the patients followed had 21 hydroxylase deficiencies and had 11 hydroxylase deficiencies. Unsurprisingly, we suspected adrenal insufficiency in these patients at verbal autopsy even in families with a patient with 11 hydroxylase deficiency. Other non DSD malformations or genetic disorders with apparently no link with CAH were reported in 3 families. The father of a patient reported to have hypospadias. Conclusion: each diagnosis of CAH made in our context is visible part of an iceberg. Behind a diagnosis of CAH made in our setting, is a long course of care, a dramatic past history revealing access to appropriate care disparity. Neonatal screening should thus be considered as an emergency.

关键词： Congenital Adrenal Hyperplasia

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Comparison of the Clinical Profile and Severity Factors of COVID-19 during the First 4 Waves in a Paediatric Population of Yaounde

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Open Journal of Pediatrics 2023年第1期13卷 125-137页

作者： Jocelyn Tony Nengom Suzanne Sap Ngo Um Louis Serge Tang Nlend Bonaventure Hollong jeannette epée Ngoué Paul Olivier Koki Ndombo Faculty of Medicine and Biomedical Sciences Department of Pediatrics University of Yaounde I Yaounde Cameroon Mother and Child Center of Chantal Biya’s Foundation Yaounde Cameroon Specialized Center for COVID-19 Patients Annex Number II of the Yaounde Central Hospital (ORCA) Yaounde Cameroon

Introduction: COVID-19 is an infectious disease that has been causing a global pandemic since 2019. Although clinical forms are generally less severe in children than in adults, children nevertheless present polymorphous clinical forms and severe cases that can lead to death. Objective: To describe the clinical presentations found in the different waves of COVID-19, and to highlight the different factors of severity. Materials and Methods: We conducted a cross-sectional study with retrospective and prospective data collection which lasted 7 months (from November 2021 to June 2022) and covered a study period from 6 March 2020 to 22 June 2022, i.e. 27 months. All patients aged 0 to 18 years, suspected of having COVID-19, confirmed by real-time RT-PCR or an antigenic Rapid Diagnostic Test or antibody were included. These patients were to be managed in the Mother and Child Centre of the Chantal Biya Foundation, as well as in the Specialised Centre for the Management of COVID patients, annex number II of the Yaoundé Central Hospital. The results were analysed using IBM SPSS.23 software. Results: We included 163 patients in our study. No paediatric patients were registered during the 3rd wave. The mean age of the patients in the study population was 13 ± 5 years with extremes from 15 days to 18 years. We had a female predominance with a sex ratio of 0.83. The most common comorbidity was asthma. The first wave presented mainly with respiratory symptoms such as dry cough and signs of respiratory distress. The second wave presented mainly with digestive symptoms such as diarrhoea, abdominal pain and vomiting. The fourth wave presented with eNT signs such as sore throat, and rhinorrhea. Factors associated with severity were mainly age less than five years (OR = 17.69), vomiting (OR = 6.50), presence of comorbidities (OR = 3.39), and alteration of vital parameters such as bradypnoea (OR = 19.68), bradycardia (OR = 6.34), tachycardia (OR = 3.73), oxygen saturation Co

关键词： COVID-19 Children Waves Clinical Profile Severity Cameroon

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Comparative Analysis of Community-Based Management of Anemia in Children before and during the COVID Pandemic

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Open Journal of Pediatrics 2022年第4期12卷 671-677页

作者： Kamo Sélangaï Doka Hélène Mekone Nkwele Isabelle jeannette epée Ngoué Tony Nengom Jocelyn Zenabou Tena Zomene Franc Ngo Um Sap Suzanne Faculty of Medicine and Biomedical Sciences University of Garoua Garoua Cameroon Pediatric Unit of the Regional Hospital of Ngaoundere Ngaoundere Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaounde Cameroon

Introduction: In low-income countries, severe anemia represents a significant risk of mortality. It is generally the consequence of a lack of correct community-based management of mild and moderate anemia and its etiologies. Our study aimed to evaluate the community practice in confronting anemia by mothers of children aged 0 - 5 years old before and during the COVID-19 period. Methods: We conducted a descriptive cross-sectional study in two phases at the pediatric ward of the regional hospital of Ngaoundere in Cameroon;before the period of the COVID-19 pandemic from December 2018 to May 2019 and during the pandemic period from December 2020 to May 2021. It was a volunteer sample. Were included in this study all mothers of children aged 0 - 5 years present in the pediatric ward at the time of the survey who agreed to freely answer our questionnaire. Results: Of the 152 mothers surveyed in the “Before COVID-19” group, 69% went to a health facility when they suspected their children were anemic, 20% gave grenadine juice (Red colored soda), 7% went to marabous, 2% bought street medicines and 2% used other home-made potions. Of the 92 mothers included in the “During COVID-19” group, the majority did not go to a health facility: 36% gave grenadine juice and other potions, 26% went to marabouts, 23% bought medicines from the street and only 13% went to a health facility;2% did nothing. The average Group rank is not statistically significantly different between the before and during the COVID-19 periods (p = 0.89). Conclusion: Community behavior and practice in confronting anemia deteriorated during the COVID-19 pandemic, with the majority of mothers resorting to non-effective out-of-hospital solutions. The consequence can be an increase in infant mortality. While waiting for the end of the pandemic, it is judicious and urgent to review the whole health system in Africa and especially in countries with limited resources. We propose developing multiple advanced strategies t

关键词： Anemia COVID-19 Community Management

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Associated Factors to Immunization Timeliness and Completion in Preterm and Low Birth Weight Infants at essos Hospital Center Yaounde

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Open Journal of Pediatrics 2021年第1期11卷 9-18页

作者： Marie Kouya Annie Carole Nga Motaze jeannette epée Ngoue Arsène Brunelle Sandie Paul Olivier Koki Ndombo Anne esther Njom Nlend Higher Institute of Medical Technology Nkolondom University of Douala Douala Cameroon essos Hospital Centre Unit of Neonatology Yaoundé Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaoundé Cameroon Pan African University of Nairobi Nairobi Kenya

Introduction: Vaccination is very often delayed in premature and low birth weight infants. However, timely vaccination is even more important in this population because of their increased susceptibility to infection. Objective: To assess immunization practice and factors associated with vaccine promptness and completeness in former preterm and low-birth-weight infants. Methods: We conducted a retrospective analytical cross-sectional study (January 2017 to February 2019). Main Measurement: Promptness and completeness at each contact, Statistical analysis was performed using R software version 3.6.2, logistic regression was used to estimate the Odds Ratio (OR) and their 95% Confidence Interval (CI). Results: We recruited 310 children aged 12 to 36 months born before 37 weeks with low birth weight, 163 (52.6%) of whom were female. Two hundred and fifty-three had received the vaccines at the indicated age, with promptness rate of 81.6%, and 97.7% had completed routine immunization at 9 months. The mean age at vaccination initiation was 6 days ±e="font-family:;" "="

关键词： Prematurity Low Birth Weight Immunization Timeliness Completion

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Acceptance and experience of HIV-Infected Adolescents in Two Hospitals in Yaoundé

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Open Journal of Pediatrics 2024年第2期14卷 435-443页

作者： Isabelle Mekone Nkwele Nelly Kamgaing Pierrette Amanda emah Manga jeannette Épée Ngoué Hélène Kamo Sélangai Claude Audrey Meguieze Nsoh Ndeh-Fofang Serge Tchoukoua Jean-Baptiste Fotso Djemo Paul Koki Ndombo Department of Pediatrics Faculty of Medicine and Biomedical Sciences University of Yaoundé I Yaoundé Cameroon Institut Supérieur des Sciences de la Santé de Bangangté Université des Montagnes Bangangté Cameroon Faculty of Medicine and Biomedical Sciences University of Garoua Garoua Cameroon

Introduction: Access to antiretroviral drugs has improved the survival of children infected with the Human Immunodeficiency Virus (HIV). As they reach adolescence, they are confronted with various constraints related to the infection and its treatment, in addition to those of the growth period they are going through. The main aim of the study was to assess the acceptance and describe the experience of HIV infection by infected adolescents but also to investigate the factors associated with good acceptance and a positive experience. Methodology: The cross-sectional analytic study concerned HIV-infected adolescents aged 15 to 19 followed up at the Chantal Biya Foundation-Mother and Child Centre (CMe-FCB) and the Yaoundé University Hospital Centre (CHUY) between February 2020 and June 2020. The study saw participants complete a questionnaire containing socio-demographic data and assessing acceptance and experience with the infection. Data analysis was accomplished using epi info software version 7.***.2.6. Results: One hundred and thirteen HIV-infected adolescents were included in the study. The sex ratio was 0.68 and the mean age was 17 years. More than half of the adolescents had a good acceptance and positive experience with the infection. Related factors were the adolescent’s perception of good health and participation in an association with other infected adolescents. Conclusion: emphasizing the psychological and educational follow-up of infected adolescents and encouraging their participation in associations for adolescents living with HIV could reduce the consequences of poor acceptance and ensure a better transition to adulthood. .

关键词： HIV Adolescent Acceptance experience

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科学化引领护肤新趋势

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商业周刊（中文版） 2024年第2期 72-73页

作者： jeannette Neumann Lennard Kok(绘图) 王非(译) 不详

希瑟·罗格斯(HeatherRogers)13岁的女儿最近说,她想要的圣诞礼物是含有透明质酸的护肤品。罗格斯说她真是受够了。“我说,‘不,你需要的只有防晒霜,其他不用说了,’”罗格斯说。她是西雅图一位通过资72格认证的皮肤科医生。她说,女儿... 详细信息

希瑟·罗格斯(HeatherRogers)13岁的女儿最近说,她想要的圣诞礼物是含有透明质酸的护肤品。罗格斯说她真是受够了。“我说,‘不,你需要的只有防晒霜,其他不用说了,’”罗格斯说。她是西雅图一位通过资72格认证的皮肤科医生。她说,女儿的要求反映了美国人当中的一种趋势,他们愈发沉迷于购买那些主要成分听上去像是直接来自实验室的产品。要是这些产品还承诺具有保湿功能,可以增强“皮肤屏障”,总之就是能够延缓皮肤老化,那就更好不过了。

关键词：皮肤科医生圣诞礼物皮肤老化防晒霜皮肤屏障透明质酸护肤品西雅图

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evaluation of Mandibular Deprogramming Using TeNS (Transcutaneous electrical Nerve Stimulation) in Patients at the Specialty Clinic of the Juarez Autonomous University of Tabasco from 2022 to 2024

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Journal of Biosciences and Medicines 2024年第7期12卷 245-251页

作者： Christian C. Aguilar-Caamal Landy V. Limonchi-Palacio Crystell G. Guzmán-Priego jeannette Ramírez-Mendoza José M. Lehmann-Mendoza Miguel A. López-Alvarado Xavier e. Moreno-enriquez Jorda A. Albarrán-Melzer Academic Division of Health Sciences Juarez Autonomous University of Tabasco Villahermosa Tabasco Mxico Cardiometabolism Laboratory Academic Division of Health Sciences Juarez Autonomous University of Tabasco Villahermosa Tabasco Mxico

Temporomandibular disorders (TMD) negatively affect quality of life, causing pain and restricted jaw movements. This study evaluates the effectiveness of Transcutaneous electrical Nerve Stimulation (TeNS) on TMD patients before orthodontic treatment at the Juarez Autonomous University of Tabasco. A quantitative, quasi-experimental study was conducted with 30 patients who met the inclusion criteria: aged 18 to 65 years, with TMJ pain symptoms, diagnosed with temporomandibular disorders using the Helkimo index, and who had provided informed consent for the study. The range of mandibular movement and the Visual Analog Scale (VAS) were measured to record values before therapy. The electrodes of the TeNS therapy were positioned on both sides of the jaw in the preauricular area and the masseter muscle, the therapy was administered for 40 minutes, utilizing a frequency of 2 - 4 Hz and a pulse duration of 300 microseconds. Following this, the range of mandibular movement and the VAS were reassessed to evaluate the outcomes., significantly improved maximum mouth opening (37.7 ± 6.4 mm to 44.6 ± 5.88 mm), right laterality (3.86 ± 1.57 mm to 5.43 ± 1.21 mm), left laterality (3.13 ± 1.63 mm to 4.53 ± 1.61 mm), protrusion (4.01 ± 1.7 mm to 5.36 ± 1.32 mm), and pain perception (4.56 ± 2.045 to 2.03 ± 1.5) (P eNS therapy enhances mandibular movement and reduces pain, making it a well-tolerated, non-invasive complementary treatment for TMD.

关键词： TeNS Opening Deprogramming electrostimulation TMJ (Temporomandibular Joint)

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epidemiological, Clinical Aspects and Outcome of Measles in a Low-Income Country in 2023

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Open Journal of Pediatrics 2024年第1期14卷 139-148页

作者： Sime Tchouamo Arielle Annick enyama Dominique Noukeu Diomède Atyam ekotto Marie Christine Abouame Palma Haoua epee Ngoue jeannette Kago Tague Daniel Armand Touka eric Brice Tasse Simo Nathalie Ines Nguéfack Félicité Faculty of Medicine and Pharmaceutical Sciences of University of Dschang Dschang Cameroon Gynaeco-Obstetric and Pediatric Hospital of Yaounde Yaounde Cameroon Gynaeco-Obstetric and Pediatric Hospital of Douala Douala Cameroon Regional Annex Hospital of Dschang Dschang Cameroon Faculty of Medicine and Biomedical Sciences of University of Garoua Garoua Cameroon Faculty of Medicine and Biomedical Sciences of University of Yaounde 1 Yaounde Cameroon West Regional Delegation of Public Health Bafoussam Cameroon

Introduction: Measles remains a worrying health problem in sub-Saharan African countries. There have been measles outbreaks in Cameroon with the most recent occurring between October 2022 and September 2023. The Centre region of Cameroon was the most affected in the country and being at the frontline of the fight against this illness, we conducted this study in order to determine the epidemiological and clinical characteristics as well as the outcome of children who contracted the measles and were hospitalized at the Yaoundé Gynaeco-Obstetric and Pediatric Hospital. Methodology: We conducted a cross-sectional descriptive and prospective study for one year from October 2022 to November 2023 corresponding to the duration of the outbreak. We included all children admitted in the pediatric unit for measles and its complications during this period. Results: In total, 60 children were enrolled. Their caregivers were mostly their mothers who had a mean age of 34.71 ± 9.55 years living in significant precarious conditions for the majority. The median age of children was 16 months (09 - 30 months). Twenty six percent of children (16) were less than 9 months. Girls were predominant (55%). Most children were not up to date with their routine epI vaccination (80%) and most did not receive the measles and Rubella vaccine (76.67%). Clinical manifestations, included fever, conjunctivitis, and cough. Skin rash and catarrh (98.33% and 86.67% respectively) are the case definition signs of measles. The outcome was unfavorable for 4 children. One had a neurological disorder: coma and three presented with pneumonia and severe respiratory distress (6.67%). Conclusion: Measles is still being a reality and claiming lives in our context, emphasis should be made on immunization coverage and if possible, advocacies should be formulated to decrease the age of measles vaccine administration.

关键词： Measles Complications Low-Income Countries

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LVMH路威酪轩集团董事会主席兼CeO 伯纳德·阿尔诺:我们的每项计划都着眼于未来

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商业周刊（中文版） 2024年第12期 42-49页

作者： BRAD STONe ANGeLINA RASCOUeT RUVeN AFANADOR(摄影) jeannette Neumann Natalie Wong Daniela Wei Shirley Zhao 杨飞(译) 不详

LVMH路威酪轩集团已将全球众多奢侈品牌收入囊中,如今又成为2024年巴黎奥运会的最大赞助商。阿尔诺认为,该集团作为法国文化旗手,有责任让奥运会取得成功每周六早上,伯纳德·阿尔诺(BernardArnault)都会在副手、保镖和子女轮流担当的随... 详细信息

LVMH路威酪轩集团已将全球众多奢侈品牌收入囊中,如今又成为2024年巴黎奥运会的最大赞助商。阿尔诺认为,该集团作为法国文化旗手,有责任让奥运会取得成功每周六早上,伯纳德·阿尔诺(BernardArnault)都会在副手、保镖和子女轮流担当的随从陪同下,花几个小时的时间巡查他供奉着手袋、时装、珠宝和昂贵手表的时尚神殿。

关键词：集团董事会奢侈品牌阿尔诺奥运会伯纳德 CeO 赞助商

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