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Storylines of family medicine Ⅵ:ways of being—in the office with patients

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Family medicine and Community Health 2024年第S3期12卷 52-60页

作者： William B Ventres Leslie A Stone Lisa A LaVallee David Loxterkamp Jonisha R Brown Dael m Waxman Peter S Dorward jeanne Cawse-Lucas Larry B mauksch Autumn m Kieber-Emmons Benjamin F Crabtree William L miller Veronica m Brohm Timothy P Daaleman Kelly Bossenbroek Fedoriw Family and Preventive medicine University of Arkansas for Medical Sciences College of MedicineLittle RockArkansasUSA mAHEC Family medicine Residency Mountain Area Health Education CenterAshevilleNorth CarolinaUSA Bucksport Regional Health Center BucksportMaineUSA Family medicine Atrium HealthCharlotteNorth CarolinaUSA Southfield medical Practice EdinburghUK Family medicine University of Washington School of MedicineSeattleWashingtonUSA Family medicine Lehigh Valley Health NetworkAllentownPennsylvaniaUSA morsani College of medicine University of South FloridaTampaFloridaUSA Family medicine and Community Health Rutgers Robert Wood Johnson Medical SchoolPiscatawayNew JerseyUSA Cancer Institute of New Jersey New BrunswickNew JerseyUSA Family medicine UNC School of MedicineChapel HillNorth CarolinaUSA

Storylines of Family medicine is a 12-part series of thematically linked mini-essays with accompanying illustrations that explore the many dimensions of family medicine,as interpreted by individual family physicians and medical educators in the USA and elsewhere around the ***‘Ⅵ:ways of being—in the office with patients’,authors address the following themes:‘Patient-centred care—cultivating deep listening skills’,‘Doctor as witness’,‘Words matter’,‘Understanding others—metaphor and its use in medicine’,‘Communicating with patients—making good use of time’,‘The patient-centred medical home—aspirations for the future’,‘Routine,ceremony or drama?’and‘The life course’.may readers better appreciate the nuances of patient care through these essays.

关键词： centre illustration dimensions

Detailing Losses in the m/m/1/1 Transient Loss System

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Acta mathematicae Applicatae Sinica 2018年第2期34卷 373-385页

作者： Pierpaolo ferrante National Workers Compensation Authority (INAIL) Department of Occupational and Environmental Medicine Epidemiology and Hygiene (DiMEILA)

This paper is aimed at investigating the transient losses in the m/m/1/1 Erlang loss system. We evaluate the explicit form of the probability distribution of the number of losses in the time interval [0, t） and provide two alternative representations： one based on the iterated derivatives of hyperbolic sinus and cosine and the other on the spherical modified Bessel function of the second kind. The mathematical structures of the transient loss rate and of the transient probability of losing all customers are described and several analytical properties are derived.

关键词： transient losses transient loss rate Erlang bessel functions

Disinfection byproduct regulatory compliance surrogates and bromide-associated risk

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Journal of Environmental Sciences 2017年第8期29卷 191-207页

作者： Chelsea Kolb Royce A.Francis jeanne m.VanBriesen Department of Ciuil and Environmental Engineering Carnegie Mellon Uniuersity Pittsburgh PA 15213 USA Department of Engineering management and Systems Engineering The George Washington University Washington DC 20052 USA Department of Engineering and Public Policy Carnegie Mellon University Pittsburgh PA 15213 USA

Natural and anthropogenic factors can alter bromide concentrations in drinking water sources. Increasing source water bromide concentrations increases the formation and alters the speciation of disinfection byproducts（DBPs） formed during drinking water *** DBPs are more toxic than their chlorinated analogs, and thus have a greater impact on human health. However, DBPs are regulated based on the mass sum of DBPs within a given class（e.g., trihalomethanes and haloacetic acids）, not based on species-specific risk or extent of bromine incorporation. The regulated surrogate measures are intended to protect against not only the species they directly represent, but also against unregulated DBPs that are not routinely measured. Surrogates that do not incorporate effects of increasing bromide may not adequately capture human health risk associated with drinking water when source water bromide is elevated. The present study analyzes trihalomethanes（THms）, measured as TTHm,with varying source water bromide concentrations, and assesses its correlation with brominated THm, TTHm risk and species-specific THm concentrations and associated *** potential surrogates are evaluated to assess their ability to capture THm risk under different source water bromide concentration conditions. The results of the present study indicate that TTHm does not adequately capture risk of the regulated species when source water bromide concentrations are elevated, and thus would also likely be an inadequate surrogate for many unregulated brominated species. Alternative surrogate measures,including THm3 and the bromodichloromethane concentration, are more robust surrogates for species-specific THm risk at varying source water bromide concentrations.

关键词： Disinfection byproducts Bromide Disinfection byproduct regulation Trihalomethanes Disinfection byproduct risk

Asymmetrical mate preference in recently adapted White Sands and black lava populations of Sceloporus undulatus

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Current Zoology 2013年第1期59卷 20-30页

作者： Kayla m. HARDWICK jeanne m. ROBERTSON Erica Bree ROSENBLUm Department of Biological Sciences University of Idaho Moscow ID 83844 USA Department of Biology California State University Northridge CA 91330 USA Department of Environmental Science Policy and Management University of California Berkeley CA 94720 USA

Speciation can proceed rapidly when natural and sexual selection act in concert. For example speciation can be ac- celerated when traits that confer a selective advantage in a particular habitat also influence mate preference. Studying parallel but evolutionarily independent instances of ecological divergence can illuminate the interaction between natural and sexual selection during speciation. Locally adapted populations of the eastern fence lizard Sceloporus undulatus have recently evolved in three different habitats in the Chihuahuan desert： blanched color morphs occur on the gypsum dunes of White Sands, melanic color morphs occur on the Carrizozo lava flow, and brown color morphs occur in the surrounding desert scrubland. In addition to dif- ferences in cryptic dorsal coloration, populations also differ in the size and color of ventral patches used for social signaling. This system therefore provides an opportunity to investigate the interplay of natural and sexual selection during rapid ecological speci- ation. We used mate preference experiments to determine whether locally adapted populations may exhibit the early stages of be- havioral reproductive isolation. We observed an asymmetrical mate preference in this system; White Sands males preferentially courted local females, while males from dark soils and black lava populations did not exhibit a preference for local mates. We also found that female behavior and ventral patch phenotype were associated with male courtship. Our results suggest that the observed preference for local mates evolved at White Sands, and we discuss the possible link between local adaptation and traits involved in mate preference in this system [Current Zoology 59 （1）： 20-30, 2013].

关键词： Eastem fence lizard magic trait Ecological speciation Sexual signaling Courtship mate preference asymmetry

Nonalcoholic fatty liver disease and type 2 diabetes: a burgeoning problem with unclear solutions

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Hepatobiliary Surgery and Nutrition 2020年第4期9卷 514-517页

作者： mariana Lazo jeanne m.Clark Division of General Internal medicine School of MedicineJohns Hopkins UniversityBaltimoreMDUSA Division of Gastroenterology&Hepatology Johns Hopkins University School of MedicineBaltimoreMDUSA

The association between chronic liver disease and diabetes has been known for long time,with reports in the literature as early as in 1952(1).Currently,a bidirectional association between type 2 diabetes and nonalcoholic fatty liver disease(NAFLD)has become more widely accepted,probably as a result of the common risk factors(e.g.,obesity)and pathophysiology(e.g.,insulin resistance)(2).

关键词： diabetes liver NAFLD

The Essential Oil of Ocimum americanum from Senegal and Gambia as a Source of methyleugenol for the Control of Bactrocera dorsalis, Fruit Fly

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Journal of Agricultural Chemistry and Environment 2024年第1期13卷 133-141页

作者： Yoro Tine Antonio Alain Coffi Sinzogan Ousmane Ndiaye Cebastiana Sambou Alioune Diallo Ismaila mbenga Kemo Badji El Hadji Omar Dieng Assa Balayara jeanne Diatta Cheikhouna Gaye Julien Paolini Jean Costa Alassane Wele Saliou Ngom Laboratoire de Chimie Organique et Thérapeutique Faculté de Médecine Pharmacie et Odontologie Université Cheikh Anta Diop Dakar Sénégal Faculte des Sciences Agronomiques Universite d’Abomey Calavi Cotonou Benin Ecole Nationale Supérieure d’Agriculture (ENSA) Université Iba Der Thiam de Thiès Thiès Sénégal Direction de la Protection des Végétaux Rufisque Sénégal Laboratoire de Chimie des Produits Naturels Université de Corse Corte France National Agricultural Research Institute (NARI) Sere Kunda Gambia Institut Sénégalais de Recherches Agricoles (ISRA) Dakar Sénégal

The fruit fly, Bactrocera dorsalis (Diptera: Tephritidae) is one of the most important pests in all mango-producing areas, particularly in West Africa. In Senegal, O. americanum leaves have been used for several years to control this fly. However, to our knowledge, no chemical studies have been carried out. Thus, the aim of this study is to determine the chemical composition of the essential oil of O. americanum leaves collected in Senegal and Gambia. The essential oil obtained by hydrodistillation of these leaves is analyzed by GC/FID and GC/mS. Yields of essential oils from O. americanum leaves are 3.84% and 2.13%, respectively. Analysis of these essential oils by GC/FID and GC/mS allowed the identification of 23 compounds representing almost 100% of the total compositions. These essential oils are mainly dominated by methyleugenol (72.0% and 75.8%, respectively). Other components in significant percent are trans-β-caryophyllene (13.9% and 13.0%, respectively), germacrene D (4.1% and 3.7%, respectively), β-elemene (3.3% and 0.9%, respectively). Due to the high methyleugenol content, this study explains the attractive potential of O. americanum towards B. dorsalis. In perspective, we plan to evaluate the attractive effect of the essential oil and leaf powder of O. americanum against B. dorsalis, a real pest of mango orchards in Senegal.

关键词： Ocimum americanum Essential Oils methyleugenol Bactrocera dorsalis GC/mS

Long-term changes in biological soil crust cover and composition

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Ecological Processes 2013年第1期2卷 54-63页

作者： Eva Dettweiler-Robinson jeanne m Ponzetti Jonathan D Bakker Department of Biology University of New MexicoMSC0320201 University of New MexicoAlbuquerqueNM 98131U.S.A. 2914 Central St.SE OlympiaWA 98501U.S.A. School of Environmental and Forest Sciences University of WashingtonBox 354115SeattleWA98195-4115U.S.A.

Introduction:Communities change over time due to disturbances,variations in climate,and species *** soil crust communities are important because they contribute to erosion control and nutrient *** types may respond differently to changes in environmental conditions:single-celled organisms and bryophytes quickly recover after a disturbance,while lichens are slow growing and dominate favorable *** change in crusts has seldom been assessed using repeated *** this study,we hypothesized that changes in crust composition were related to disturbance,topographic position,and invasive ***:We monitored permanent plots in the Columbia Basin in 1999 and 2010 and compared changes in crust composition,cover,richness,and turnover with predictor variables of herbivore exclosure,elevation,heat load index,time since fire,presence of an invasive grass,and change in cover of the invasive ***:Bryophytes were cosmopolitan with high *** lichens did not change *** taxa differed by monitoring *** and total crust cover declined,and there was lower turnover outside of herbivore *** cover did not change *** that burned recently had high *** in taxon richness was correlated with presence of an invasive grass in *** in cover of the invasive grass was positively related to proportional loss and negatively related to ***:Composition and turnover metrics differed significantly over 11 years,though cover was more stable between *** study can be a baseline for assessing change in crust composition due to anthropogenic influences.

关键词： Biological soil crust Columbia basin Composition change Taxa turnover rate Fire Bromus tectorum Livestock exclosure

Characterization of IL-12 Receptor β1 Chain (IL-12Rβ1)-Deficient miceIL-12Rβ1 Is an Essential Component of the Functional mouse IL-12 Receptor

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Characterization of IL-12 Receptor β1 Chain (IL-12Rβ1)-Def...

Prognosis Factors of Urinary Quality of Life in Parkinson Disease

作者： Jessica ferrante maurice K．Gately jeanne magram Department of Inflammation/Autoimmune Diseases Hoffmann-La Roche Inc.NutleyNJ 07110USA

Two chains of the IL-12R,IL-12Rβ1 and IL-12Rβ2,have recently been *** determine the role of IL-12Rβ1 in mediating the biologic functions of IL-12 in mice,we have generated IL-12Rβ1-deficient (IL-12Rβ1-/-) mice by targeted mutation in ES *** A-activated splenocytes from IL-12Rβ1 + / + mice displayed both high and low affinity IL-12-binding sites, whereas Can A-activated splenocytes from IL-12Rβ1-/- mice expressed only low affinity IL-12-binding sites. Consistent with the expression of low affinity IL-12-binding sites on IL-12Rβ1-/- lymphoblasts, these cells expressed nor-

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Open Journal of Therapy and Rehabilitation 2024年第1期12卷 10-17页

作者： Ngor Side Diagne Sakhi Othman Ababacar mamadou Gueye marie jeanne Sakho Fatou Dialo mboup Amélie Ndeye makarame Sy Papa Ndiouga Lo Ba Seydina Ousmane Anna modji Basse maouly Fall Adjaratou Dieynaba Sow moustapha Ndiaye Amadou Gallo Diop Physical médicine and Rehabilitation Department Fann Teaching Hospital Dakar Senegal Neurology Department Pikine Hospital Dakar Senegal Physical médicine and Rehabilitation Department Ibn Rochd Teaching Hospital Casablanca Morocco Physical médicine and Rehabilitation Department Military Hospital Dakar Senegal Neurology Department Fann Teaching Hospital Dakar Senegal

Introduction: Quality of life in Parkinson disease is not necessary linked to motor symptoms. It’s correlated of overactive bladders and prostatic symptoms. Prognosis factors of urinary quality of life are unknown. Objectives: Our study aims to find prognosis factors of quality of life associated specifically of urinary disorders in PD. Patients and methods: We conducted a transversal, analytic and descriptive study in Physical medicine, and Neurology departments, Fann Teaching Hospital, Dakar and included patients followed for treatment of PD. Urinary disorders, quality of life and functional autonomy were assessed respectively by Urinary Symptoms Profile (USP), Qualiven Short Form, Schwab and England Scale. Results: 38 patients presented PD, with a mean age of 60.89 ± 13.6 years and sex-ratio of 2.45. mean duration of PD was 3.1 ± 2.9 years. Urinary disorders were found in 47.36% and dominated by incontinence (88.88%) and overactive bladders (88.88%) which were minor in more than 55%. Quality of life was impaired in 88.88% of cases. minor forms (43.75%) were predominant and constraint dimension (50%) was the most severely altered. Prognosis factors for quality of life of urinary disorders were PD stages (0.046) and functional autonomy (0.042). Discussion and conclusion: Urinary disorders in PD are common, impaired quality of life, especially the constraint dimension, depends on stage of evolution of PD and functional autonomy of patients.

关键词： Urinary Quality of Life Parkinson Disease Dakar