检索结果-南通市图书馆

微观造梦空间jean francois Rauzier超维摄影

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

摄影之友 2013年第9期 52-57页

作者： jean francois Rauzier(图/文) 曾南(整理) 不详

将徽观的世界逬行重新的拼贴,从而生成一个充满想象的超现实空间,这是摄影师让·弗朗索瓦·赫奇耶一直追求的,他每一张作品都拍摄了上干张局部特写照片,最终生成一个充满个人体会的梦境超维空间。

关键词：摄影师微观现实空间特写照片成一拍摄

Iron- and Ferritin-Dependent Reactive Oxygen Species Distribution： Impact on Arabidopsis Root System Architecture

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2015年第3期8卷 439-453页

作者： Guilhem Reyt Soukaina Boudouf Jossia Boucherez Frédéric Gaymard jean-francois Briat Biochimie et Physiologie Moléculaire des Plantes Centre National de la Recherche Scientifique Institut National de la Recherche Agronomique Université Montpellier 2 SupAgro. Bat 7 2 place Viala 34060 Montpellier Cedex 1 France present address: Institute of Biological and Environmental Sciences University of Aberdeen Cruickshank Building St Machar Drive Aberdeen Scotland AB243UU UK

Iron （Fe） homeostasis is integrated with the production of reactive oxygen species （ROS）, and distribution at the root tip participates in the control of root growth. Excess Fe increases ferritin abundance, enabling the storage of Fe, which contributes to protection of plants against Fe-induced oxidative stress. AtFerl and AtFer3 are the two ferritin genes expressed in the meristematic zone, pericycle and endodermis of theAra- bidopsis thaliana root, and it is in these regions that we observe Fe stained dots. This staining disappears in the triple ferl-3-4 ferritin mutant. Fe excess decreases primary root length in the same way in wild-type and in ferl-3-4 mutant. In contrast, the Fe-mediated decrease of lateral root （LR） length and density is enhanced in ferl-3-4 plants due to a defect in LR emergence. We observe that this interaction between excess Fe, ferritin, and root system architecture （RSA） is in part mediated by the H_2O_2/O2·^- balance between the root cell proliferation and differentiation zones regulated by the UPB1 transcription factor. Meristem size is also decreased in response to Fe excess in ferritin mutant plants, implicating cell cycle arrest mediated by the ROS-activated SMR5/SMR7 cyclin-dependent kinase inhibitors pathway in the interaction between Fe and RSA.

关键词： roots development oxidative stress reactive oxygen species balance iron ferritins

Glucose regulates LXRα subcellular localization and function in rat pancreatic β-cells

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cell Research 2006年第7期16卷 661-670页

作者： AudreyHelleboid-Chapman StéphaneHelleboidHeidelindeJakel CatherineTimmerman Christian Sergheraert francois Pattou JamilaFruchart-Najib jean-CharlesFruchart Atherosclerosis Department UR 545 INSERMthe Faculty of PharmacyLille 2 University1 rue du Professeur Calmette BP245Lille cedex 59019France Synthesis Structure and Biomolecule FunctionUMR 8525 CNRSPasteur Institute of LilleLille 2 UniversityLilleFrance Cell Therapy for Diabetes ERIT-M 0106Facultyof Medecine University of Lille 2/INSERMLille 59045France

Liver X receptors(LXRs)are members of the nuclear receptor superfamily,which have been implicated in lipid ho-meostasis and more recently in glucose ***,we show that glucose does not change LXRα protein level,but affects its localization in pancreatic β-***α is found in the nucleus at 8 mM glucose and in the cytoplasm at4.2 *** of glucose translocates LXRα from the cytoplasm into the ***,after the activation ofLXR by its synthetic non-steroidal agonist(T0901317),insulin secretion and glucose uptake are increased at 8 mM anddecreased at 4.2 mM glucose in a dose-dependent ***,at low glucose condition,okadaic acid reversedLXRα effect on insulin secretion,suggesting the involvement of glucose signaling through a phosphorylation-dependentmechanism.

关键词： LXR β-cells insulin secretion glucose uptake subcellular localization

Rapid increase in numbers and change of land-use in two expanding Columbidae species(Columba palumbus and Streptopelia decaocto)in Algeria

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Chinese Birds 2015年第4期6卷 246-254页

作者： Djamel Bendjoudi jean-francois Voisin Salaheddine Doumandji Amel Merabet Nassima Benyounes Haroun Chenchouni Department of Biology of Populations and Organisms Faculty of Natural and Life SciencesUniversity of Blida Muséum National d’Histoire Naturelle Department of Agricultural and Forestry Zoology National Superior School of Agronomy(ENSA)-El Harrach Department of Biology Faculty of SciencesUniversity of M’Hamed Bougara Department of Natural and Life Sciences Faculty of Exact Sciences and Natural and Life SciencesUniversity of Tebessa Department of Natural and Life Sciences Faculty of SciencesUniversity of El Hadj Lakhdar

Background: Investigating population ecology of urban bird species,particularly the invasive and expending spe?cies,is the key for the success of urban management and planning ***: Populations of two Columbidae species,the Woodpigeon(Columba palumbus) and the Eurasian Collared Dove(Streptopelia decaocto),were monitored from 1992 to 2010 in the Algiers Sahel,the Mitidja Plain and surround?ing areas(Northern Algeria).Monitoring of species densities was performed by the mapping?plot *** foraging flight routes of Woodpigeon and the distribution of Eurasian Collared Dove were assessed by systematic ***: The number of counted birds was statistically constant at first years of the survey,and then increased sig?nificantly,beginning from low numbers,their densities accelerated sharply between 2001 and 2006,then reached to an equilibrium *** significant increase in Woodpigeon's population could be explained by the reduced hunt?ing pressure and by species adaptation to new food resources provided by nearby ***,monitoring of flight directions of the species revealed the use of agricultural landscapes and habitats,which is a good indicator explaining adaptation and trophic niche of the *** occurrence of the Eurasian Collared Dove in Algiers began in *** density experienced a rapid increase with similar trend pattern as that of *** distributional range is confined mainly in suburban environments of the Mitidja ***: The modifications of habitats,urbanization increase and the lessening of hunting in the Mitidja Plain facilitated the rapid expansion of the Eurasian Collared Dove and Woodpigeon as well contributed to the increase in their numbers over time.

关键词： Columba palumbus Flight routes Mitidja plain Population dynamics Streptopelia decaocto

Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Molecular Cell Biology 2011年第5期3卷 301-308页

作者： Mohamed Abu-Farha Sylvain Lanouette Fred Elisma Veronique Tremblay Jeffery Butson Daniel Figeys jean-francois Couture Ottawa Institute of Systems Biology Department of BiochemistryMicrobiology and ImmunologyUniversity of Ottawa451 Smyth RoadRoger-Guindon HallOttawaONK1H8M5Canada Biochemistry and Molecular Biology Unit Dasman Diabetes InstituteDasman 15462Kuwait

The SMYD(SET and MYND domain)family of lysine methyltransferases(KMTs)plays pivotal roles in various cellular processes,including gene expression regulation and DNA damage *** identified as genuine histone methyltransferases,specific members of this family have recently been shown to methylate non-histone proteins such as p53,VEGFR,and the retinoblastoma tumor suppressor(pRb).To gain further functional insights into this family of KMTs,we generated the protein interaction network for three different human SMYD proteins(SMYD2,SMYD3,and SMYD5).Characterization of each SMYD protein network revealed that they associate with both shared and unique sets of *** those,we found that HSP90 and several of its co-chaperones interact specifically with the tetratrico peptide repeat(TPR)-containing SMYD2 and ***,using proteomic and biochemical techniques,we provide evidence that SMYD2 methylates K209 and K615 on HSP90 nucleotide-binding and dimerization domains,*** addition,we found that each methylation site displays unique reactivity in regard to the presence of HSP90 co-chaperones,pH,and demethylation by the lysine amine oxidase LSD1,suggesting that alternative mechanisms control HSP90 methylation by ***,this study highlights the ability of SMYD proteins to form unique protein complexes that may underlie their various biological functions and the SMYD2-mediated methylation of the key molecular chaperone HSP90.

关键词： SMYD proteins HSP90 lysine methylation SET domain histone methylation

Low-k integration: Gas screening for cryogenic etching and plasma damage mitigation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2019年第3期13卷 511-516页

作者： Romain Chanson Remi Dussart Thomas Tillocher P. Lefaucheux Christian Dussarrat jean francois de M arneffe IMEC v.z.w. 3001 LeuvenBelgium GREMI/University of Orleans OrleansFrance Air Liquide Laboratories TsukubaJapan

The integration of porous organo-silicate low-k materials has met a lot of technical *** of the main issues is plasma-induced damage,occurring for all plasma steps involved during interconnects *** the present paper,we focus on porous SiOCH low-k damage mitigation using cryogenic temperature so as to enable micro-capillary *** aim is to protect the porous low-k from plasma-induced damage and keep the k-value of the material unchanged,in order to limit the RC delay of interconnexion levels while shrinking the microchip *** cryogenic temperature is used to condense a gas inside the porous low-k ***,the etching process is performed at the temperature of condensation in order to keep the condensate trapped inside the material during the *** the first part of this work,the condensation properties of several gases are screened,leading to a down selection of five ***,their stability into the porous structure is evaluated at different *** of them are used for plasma damage mitigation *** mitigation is effective and shows negligible damage for one of the gases at-50℃.

关键词： low-A nanotechnology micro-electronics cryo-etching plasma processing

FOLFIRI plus bevacizumab as a second-line therapy for metastatic intrahepatic cholangiocarcinoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2015年第7期21卷 2096-2101页

作者： jean-Florian Guion-Dusserre Veronique Lorgis Julie Vincent Leila Bengrine francois Ghiringhelli Department of Medical Oncology Centre Georges-Fran?ois Leclerc Institut National de la Santé et de la Recherche Médicale University of Burgundy

AIM:To evaluate the efficacy and tolerance of FOLFIRI plus bevacizumab treatment outcome as second-line treatment for metastatic intrahepatic ***:Thirteen consecutive patients with metastatic intrahepatic cholangiocarcinoma who were refractory tofirst-line therapy consisting of gemcitabine plus oxaliplatinbased first-line chemotherapy given intravenously via intra-arterial infusion were treated with FOLFIRI[irinotecan(180 mg/m2 *** 90 min)concurrently with folinic acid(400 mg/m2 *** 120 min)followed by fluorouracil(400 mg/m2 ***)then fluorouracil 2400 mg/m2 intravenous infusion over 46 h]and bevacizumab(5mg/kg)every 2 *** response was evaluated by computed tomography scan every 4 ***:The best tumor responses using response evaluation criteria in solid tumor criteria were:complete response for 1 patient,partial response for 4 patients,and stable disease for 6 patients after 6 mo of *** response rate was 38.4%(95%CI:12.5-89)and the disease control rate was 84.5%(95%CI:42-100).Seven deaths occurred at the time of analysis,progression free survival was 8 mo(95%CI:7-16),and median overall survival was 20 mo(95%CI:8-48).No grade 4toxic events were *** grade 3 hematological toxicities and one grade 3 digestive toxicity *** adaptive reduction in chemotherapy dosage was required in 2 patients due to hematological toxicity,and a delay in chemotherapy cycles was required for 3 ***:FOLFIRI plus bevacizumab combination treatment showed promising efficacy and safety as second-line treatment for metastatic intrahepatic cholangiocarcinoma after failure of the first-line treatment of gemcitabine plus oxaliplatin chemotherapy.

关键词： Biliary tract cancer Intrahepatic cholangiocarcino

Facilitated Fe Nutrition by Phenolic Compounds Excreted by the Arabidopsis ABCG37/PDR9 Transporter Requires the IRT1/FRO2 High-Affinity Root Fe^2＋ Transport System

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2016年第3期9卷 485-488页

作者： Pierre Fourcroy Nicolas Tissot Frederic Gaymard jean-francois Briat Christian Dubos Biochimie et Physiologie Moldculaire des Plantes Centre National de la Recherche Scientifique Institut National de la Recherche Agronomique Universite Montpellier SupAgro Bat 7 2 place Viala 34060 Montpellier Cedex 1 France

Iron （Fe） is an essential metal nutrient for plant productivity and plant product quality （Briat et al., 2015）. Fe exists under two forms, ferrous （Fe^2＋） or ferric （Fe^3＋）, and is very reactive with oxygen, explaining why Fe plant nutrition is dependent upon both Fe chelation and Fe reduction. Fe availability in the soil is pH dependent, this metal being particularly insoluble in its ferric form in calcareous soils, representing one-third of the world＇s cultivated soils. Consequently, plants grown on these soils, in particular non-graminaceous plants, often suffer from Fe deficiency, which alters their growth.

关键词： explaining dependent calcareous

Impact of photocatalytic remediation of pollutants on urban air quality

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2016年第5期10卷 37-47页

作者： Christian GEORGE Anne BEELDENS Fotios BARMPAS jean-francois DOUSSIN Giuseppe MANGANELLI Hartmut HERRMANN Jorg KLEFFMANN Abdelwahid MELLOUKI Universite Lyon 1 CNRS UMR 5256 IRCELYON Institut de recherches sur la catalyse et l'environnement de Lyon Villeurbanne F-69626 France Belgian Road Research Centre (BRRC) Woluwedal 42-1200 Brussels Belgium Laboratory of Heat Transfer and Environmental Engineering (LHTEE) Aristotle University of Thessaloniki Box 483 GR 54124 Thessaloniki Greece LISA UMR CNRS 7583 Universite Paris Est Creteil et Universite Paris Diderot Institut Pierre Simon Laplace Crrteil 94010 France 5 CTG Italcementi Group Via Stezzano 87 24126 Bergamo Italy CTG Italcementi Group Via Stezzano 87 24126 Bergamo Italy Physikalische und Theoretische Chemie / School of Mathematics and Natural Sciences Bergische Universitat Wuppertal (BUW) 42119 Wuppertal Germany Leibniz-Institut fur Troposphairenforschunge.V. (TROPOS) Atmospheric Chemistry Department 04318 Leipzig Germany Institut de Combustion Aerothermique Reactivite et Environnement (ICARE) CNRS (UPR 3021)/OSUC IC Avenue de la Recherche Scientifique Orleans 457071 France

In the recent years, photocatalytic self-cleaning and ＂depolluting＂ materials have been suggested as a remediation technology mainly for NOx and aromatic VOCs in urban areas. A number of products incorporating the aforementioned technology have been made commercially available with the aim to improve urban air quality. These commercial products are based on the photocatalytic properties of a thin layer of TiO2 at the surface of the material （such as glass, pavement, etc.） or embedded in paints or concrete. The use of TiO2 photocatalysts as an emerging air pollution control technology has been reported in many locations worldwide. However, up to now, the effectiveness measured in situ and theexpected positive impact on air quality of this relatively new technology has only been demonstrated in a limited manner. Assessing and demonstrating the effectiveness of these depolluting techniques in real scale applications aims to create a real added value, in terms of policy making （i.e., implementing air quality strategies） and economics （by providing a demonstration of the actual performance of a new technique）.

关键词： Photocatalysis Air pollution Depollution efficiency NOx VOC Air quality abatement and management