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Metabolic syndrome,levels of androgens,and changes of erectile dysfunction and quality of life impairment 1 year after radical prostatectomy

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Asian Journal of Andrology 2021年第4期23卷 370-375页

作者： Yann Neuzillet Mathieu Rouanne jean-françois dreyfus jean-Pierre Raynaud Marc Schneider Morgan Roupret Sarah drouin Marc Galiano Xavier Cathelinau Thierry Lebret Henry Botto department of Urology Hospital FochUVSQ-Paris-Saclay UniversitySuresnes 92150France department of Clinical Research and Innovation Hospital FochUVSQ-Paris-Saclay UniversitySuresnes 92150France Sorbonne University Paris 75013France department of Urology Hospital Louis PasteurColmar 68000France department of Urology Hôpital Pitié-SalpêtrièreAssistance Publique-Hôpitaux de ParisSorbonne UniversityParis 75013France department of Urology Montsouris InstituteParis-Descartes UniversityParis 75014France

Robust data evaluating the association of preoperative parameters of the patients with quality of life after radical prostatectomy are *** investigated whether clinical and biological preoperative characteristics of the patients were associated with impaired patient-reported quality of life(QoL)and sexual outcomes 1 year after radical *** evaluated patient-reported outcomes among the 1343 men participating in the AndroCan trial(NCT02235142).QoL and erectile dysfunction(Ed)were assessed before and 1 year after radical prostatectomy using validated self-assessment questionnaires(Aging Male's Symptoms[AMS]and the 5-item abridged version of the International Index of Erectile Function[IIEF5]).At baseline,1194 patients(88.9%)accepted to participate.A total of 750(55.8%)patients answered the 1-year postoperative *** of them,only 378(50.4%of responders)provided answers that could be used for *** year after prostatectomy,Ed had worsened by 8.0(95%confidence interval[CI]:7.3–8.7;Pd by 2.8(95%CI:1.7–3.8;Pd scores 1 year postsurgery were positively correlated with preoperative age and percentage of fat mass,and negatively correlated with total cholesterol,dehydroepiandrosterone(dHEA),and androstenediol(d5);AMS were poorly correlated with preoperative *** and sexual symptoms significantly worsened after radical *** bioavailable testosterone levels were significantly correlated with smaller changes on AMS somatic subscores *** findings may be used to inform patients with newly diagnosed prostate cancer.

关键词： metabolic syndrome quality of life radical prostatectomy sexual outcomes testosterone deficiency

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Honeydew volatile emission acts as a kairomonal message for the Asian lady beetle Harmonia axyridis （Coleoptera： Coccinellidae）

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Insect Science 2012年第4期19卷 498-506页

作者： Pascal d. Leroy Stephanie Heuskin Ahmed Sabri fran( ois J. Verheggen Julien Farmakidis Georges Lognay Philippe Thonart jean-Paul Wathelet Yves Brostaux Eric Haubruge departments of Functional and Evolutionary Entomology departments of Analytical Chemistry University of Liege Gembloux Agro-BioTech Walloon Center of Industrial Biology University of Liege B40 4000 Sart-Tilman departments of General and Organic Chemistry departments of Appfied Statistics Computer Science and Mathematics University of Liege Gembloux Agro-Bio Tech Gembloux Belgium

The Asian lady beetle Harmonia axyridis Pallas is considered as an invasive species in most territories where it has been introduced. Because aphid honeydew acts as an attraetant for many aphid predators and parasitoids, the objectives of this work were to collect and identify the volatile compounds released from the aphid excretory product to evaluate how these semiochemicals could affect the H. axyridis foraging behavior. Twelve volatile chemicals were identified from the Megoura viciae Buckton honeydew including four alcohols, three ketones, three aldehydes, a pyrazine and a monoterpene. The volatiles 3-methyl-l-butanol and 3-methyl-butanal were highlighted as the two most abundant semiochemicals released from the M. viciae honeydew. Vieia faba L. plants treated with crude honeydew attracted more than 80% of the tested individuals with 40% of attracted beetles located on the plant. Four volatile compounds （3-hydroxy-2-butanone, 3-methyl-butanal, 3-methyl-1-butanol and limonene） were also highlighted to attract more than 75% of the coccinellids toward the odor source and to locate about 35% of them on the plants. Limonene was the most efficient attractant since 89% of the H. axyridis responded to this odor. The use of the identified semiochemicals as well as the composition of an artificial honeydew could certainly be helpful to control the dispersal of the Asian lady beetle H. axyridis.

关键词： aphid honeydew attractant Harmonia axyridis kairomone semiochemicals

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Global parasite and Rattus rodent invasions: The consequences for rodent-borne diseases

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Integrative Zoology 2015年第5期10卷 409-423页

作者： Serge MORANd Frédéric BORdES Hsuan-Wien CHEN Julien CLAUdE jean-françois COSSON Maxime GALAN GáborÁCZIRJÁK Alex d GREENWOOd Alice LATINNE Johan MICHAUX Alexis RIBAS Centre National de la Recherche Scientifique(CNRS)-Centre de coopération Internationale en Recherche Agronomique pour le développement(CIRAd)Animal et Gestion Intégrée des Risques Centre d’Infectiologie Christophe Mérieux du LaosVientianeLao PDR department of Helminthology Faculty of Tropical MedicineMahidol UniversityBangkokThailand Institut des Sciences de l’Evolution Centre National de la Recherche Scientifique(CNRS)-Universitéde Montpellier-Institut de Recherche pour le Développement(IRD)MontpellierFrance department of Biological Resources National Chiayi UniversityChiayi CityTaiwanChina Institut National de la Recherche Agronomique(INRA) Centre de Biologie et de Gestion des PopulationsBaillarguetFrance Institut National de la Recherche Agronomique(INRA) UMR Biologie et Immunologie Parasitaire Agence Nationale de SécuritéSanitaire de l’Alimentationde l’Environnement et du Travail sesMaisons-AlfortFrance Leibniz Institute for Zoo and Wildlife Research.department of Wildlife diseases 10315 BerlinGermany Conservation Genetics Unit.University of Liège 4000 Liège Belgium Biodiversity Research Group Faculty of ScienceUdon Thani Rajabhat UniversityUdon ThaniThailand

We summarize the current knowledge on parasitism-related invasion processes of the globally invasive Rattus lineages,originating from Asia,and how these invasions have impacted the local epidemiology of rodent-borne *** play an important role in the invasion processes and successes of their hosts through multiple biological mechanisms such as“parasite release,”“immunocompetence advantage,”“biotic resistance”and“novel weapon.”Parasites may also greatly increase the impact of invasions by spillover of parasites and other pathogens,introduced with invasive hosts,into new hosts,potentially leading to novel emerging *** potential impact is the ability of the invader to amplify local parasites by *** both cases,local fauna and humans may be exposed to new health risks,which may decrease biodiversity and potentially cause increases in human morbidity and *** we review the current knowledge on these processes and propose some research priorities.

关键词： biological invasion immunocompetence parasite release spillback spillover

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Educated consumers don't believe artificial meat is the solution to the problems with the meat industry

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Journal of Integrative Agriculture 2015年第2期14卷 273-284页

作者： Aurélie Hocquette Carla Lambert Clémentine Sinquin Laure Peterolff Zoé Wagner Sarah P F Bonny André Lebert jean-franois Hocquette france Business School (FBS) 4 Boulevard Trudaine Clermont-Ferrand Cedex 1 63037 France Clermont Université Polytech 24 avenue des Landais Aubière Cedex 61177 France School of Veterinary and Life Sciences Murdoch University Murdoch W.A. 6150 Australia INRA UMR1213 Recherches sur les Herbivores Saint-Genès Champanelle F-63122 France Clermont Université Vet Agro Sup UMR1213 Recherches sur les Herbivores Saint Genès Champanelle F-63122 France

The production of in vitro meat by cell culture has been suggested by some scientists as one solution to address the major challenges facing our society. Firstly, consumers would like the meat industry to reduce potential discomfort of animals on modern farms, or even to avoid killing animals to eat them. Secondly, citizens would like meat producers to reduce potential environmental deterioration by livestock and finally, there is a need to reduce world hunger by increasing protein resources while the global population is predicted to grow rapidly. According to its promoters, artificial meat has a potential to make eating animals unnecessary, to reduce carbon footprint of meat production and to satisfy all the nutritional needs and desires of consumers and citizens. To check these assumptions, a total of 817 educated people（mainly scientists and students） were interviewed worldwide by internet in addition to 865 French educated people. We also interviewed 208 persons（mainly scientists） after an oral presentation regarding artificial meat. Results of the three surveys were similar, but differed between males and females. More than half of the respondents believed that ＂artificial meat＂ was feasible and realistic. However, there was no majority to think that artificial meat will be healthy and tasty, except respondents who were in favour of artificial meat. A large majority of the respondents believed that the meat industry is facing important problems related to the protection of the environment, animal welfare or inefficient meat production to feed humanity. However, respondents did not believe that artificial meat will be the solution to solve the mentioned problems with the meat industry, especially respondents who were against artificial meat. The vast majority of consumers wished to continue to eat meat even they would accept to consume less meat in a context of increasing food needs. Only a minority of respondents（from 5 to 11%） would recommend or accept to eat

关键词： meat production artificial meat consumers' responses

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World Journal of Hepatology 2011年第6期3卷 170-174页

作者： Nourr-Eddine Farouj jean-franois d Cadranel Ali Mofredj Vincent Jouannaud Maria Lahmiri Pierre LeLann Alain Cazier Intensive Care department Centre Hospitalier Laёnnec BP 72 60100 CreilFrance Liver Gastroenteroly and Nutrition DepartmentCentre Hospitalier Laёnnec BP 72 60100 CreilFrance Chest and Lung department Centre Hospitalier Laёnnec BP 72 60100 CreilFrance Pathological Centre Hospitalier Laёnnec BP 72 60100 CreilFrance

Sarcoidosis is a systemic granulomatous disease which may involve many *** approximately 95% of patients there is liver involvement,with noncaseating hepatic granulomas occurring in 21 to 99% of patients with *** involvement is usually asymptomatic and limited to mild to moderate abnormalities in liver *** occurrence of jaundice in sarcoidosis is rare;extensive imaging procedures and the examination of liver biopsies permit a precise *** associated with sarcoidosis has been reported in less than 20 cases and can lead to biliary cirrhosis and liver-related *** report here on a case of ductopenia-related sarcoidosis in which primary biliary cirrhosis and extrahepatic cholestasis have been carefully *** patient follow up was 8 *** ursodesoxycholic acid appears to improve liver biochemistry it does not preclude the rapid occurrence of extensive fibrosis.A review of the literature of reported cases of ductopenia related to sarcoidosis is provided.

关键词： Sarcoidosis Cholestasis ductopenia Ursodeoxycholic acid

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Precise assembly and joining of silver nanowires in three dimensions for highly conductive composite structures

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International Journal of Extreme Manufacturing 2019年第2期1卷 88-102页

作者： Ying Liu Wei Xiong da Wei Li Yao Lu Xi Huang Huan Liu Li Sha Fan Lan Jiang jean-françois Silvain Yong Feng Lu department of Electrical and Computer Engineering University of Nebraska-LincolnLincolnNE 68588-0511United States of America Wuhan National Laboratory for Optoelectronics Huazhong University of Science and Technology1037 Luoyu RoadWuhan 430074People’s Republic of China School of Mechanical Engineering Beijing Institute of TechnologyBeijing100081People’s Republic of China Institut de Chimie de la Matière Condensée de Bordeaux Avenue du Docteur Albert SchweitzerF-33608 Pessac CedexFrance

Three-dimensional(3d)electrically conductive micro/nanostructures are now a key component in a broad range of research and industry *** this work,a novel method is developed to realize metallic 3d micro/nanostructures with silver-thiol-acrylate composites via two-photon polymerization followed by femtosecond laser *** 3d micro/nanoscale conductive structures have been successfully fabricated with∼200 nm *** loading of silver nanowires(AgNWs)and joining of junctions successfully enhance the electrical conductivity of the composites from insulating to 92.9 Sm^−1 at room ***,for the first time,a reversible switching to a higher conductivity is observed,up to∼10^5Sm^−1 at 523 *** temperature-dependent conductivity of the composite is analyzed following the variable range hopping and thermal activation *** nanomaterial assembly and joining method demonstrated in this study pave a way towards a wide range of device applications,including 3d electronics,sensors,memristors,micro/nanoelectromechanical systems,and biomedical devices,etc.

关键词： precise assembly joining silver nanowires nanofabrication three dimensional

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Non-glide effects and dislocation core fields in BCC metals

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npj Computational Materials 2019年第1期5卷 178-185页

作者： Antoine Kraych Emmanuel Clouet Lucile dezerald Lisa Ventelon françois Willaime david Rodney Institut Lumière Matière UniversitéLyon 1-CNRSVilleurbanne F-69622France dEN-Service de Recherches de Métallurgie Physique CEAUniversitéParis-SaclayGif-sur-Yvette F-91191France Institut jean Lamour CNRS UMR 7198Universitéde LorraineF-54000 NancyFrance dEN-département des Matériaux pour le Nucléaire CEAUniversitéParis-SaclayGif-sur-Yvette F-91191France

A hallmark of low-temperature plasticity in body-centered cubic(BCC)metals is its departure from Schmid’s *** aspect is that non-glide stresses,which do not produce any driving force on the dislocations,may affect the yield *** show here that this effect is due to a variation of the relaxation volume of the 1/2screw dislocations during *** predict quantitatively nonglide effects by modeling the dislocation core as an Eshelby inclusion,which couples elastically to the applied *** model explains the physical origin of the generalized yield criterion classically used to include non-Schmid effects in constitutive models of BCC *** use first-principles calculations to properly account for dislocation cores and use tungsten as a reference BCC ***,the methodology developed here applies to other BCC metals,other energy models and other solids showing nonglide effects.

关键词： dislocation metals plasticity

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Population isolation shapes plant genetics, phenotype and germination in naturally patchy ecosystems

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Journal of Plant Ecology 2017年第4期10卷 649-659页

作者： Laurent de Vriendt Marc-AndréLemay Martine jean Sébastien Renaut Stéphanie Pellerin Simon Joly françois Belzile Monique Poulin département de Phytologie Facultédes Sciences de l’Agriculture et de l’AlimentationUniversitéLaval2425 rue de l’agriculture QuébecQuébec G1V 0A6Canada Québec Center for Biodiversity Science Department of BiologyMcGill UniversityStewart Biology Building1205 Dr.Penfield AvenueMontréal H3A 1B1Canada Institut de Biologie Intégrative et des Systèmes(IBIS) UniversitéLaval1030 avenue de la MédecineQuébec G1V 0A6Canada Institut de recherche en biologie végétale Département des Sciences biologiquesUniversitéde Montréal4101 Sherbrooke EstMontréal H1X 2B2Canada Jardin botanique de Montréal 4101 Sherbrooke EstMontréal H1X 2B2Canada

Aims Habitat connectivity is important in conservation since isolation can diminish the potential of a population for adaptation and increase its risk of ***,conservation of naturally patchy ecosystems such as peatlands has mainly focused on preserving specific sites with exceptional characteristics,neglecting the poten-tial interconnectivity between *** order to better under-stand plant dynamics within a peatland network,we assessed the effect of population isolation on genetic distinctiveness,phenotypic variations and germination rates using the peatland-obligate white-fringed orchid(Platanthera blephariglottis).Methods Fifteen phenotypic traits were measured for 24 individuals per pop-ulation(20 distinct populations,Quebec,Canada)and germination rates of nearly 20000 seeds were *** distinctiveness was quantified for 26 populations using single nucleotide polymor-phism markers obtained via a pooled genotyping-by-sequencing *** isolation was measured as the distance to the nearest population and as the number of populations occurring in concentric buffer zones(within a radius of 2,5 and 10 km)around the studied *** Findings All phenotypic traits showed significant differences among *** results also indicated a pattern of isolation-by-distance,which suggests that seed and/or pollen exchange is restricted ***,all phenotypic traits,as well as a reduced germination rate,were correlated with either geographic isolation or genetic *** conclude that geographic iso-lation likely restricts gene flow,which in turn may affect ***,it is imperative that conservation programs take into account the patchy nature of such ecosystems,rather than targeting a few specific sites with exceptional character for preservation.

关键词： trait variation population genetics peatland orchid Platanthera blepharigottis genotyping by sequencing GBS

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Selection of rhizobial strains differing in their nodulation kinetics under low temperature in four temperate legume species

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Grassland Research 2023年第3期2卷 197-211页

作者： Emmanuelle d'Amours Annick Bertrand jean Cloutier françois-Philippe Chalifour Annie Claessens Solen Rocher Marie Bipfubusa Chantal Giroux Chantal J.Beauchamp Agriculture and Agri-Food Canada Quebec Research and Development CentreQuebec CityQuebecCanada département de phytologie Facultédes Sciences de l'Agriculture et de l'AlimentationUniversitéLavalQuébec CityQuebecCanada Centre de recherche sur les grains(CÉROM) Saint-Mathieu-de-BeloeilQuebecCanada

Background:Winter climate change including frequent freeze-thaw episodes and shallow snow cover will have major impacts on the spring regrowth of perennial ***-bloating perennial forage legume species including sainfoin,birdsfoot trefoil,red clover,and alsike clover have been bred for their adaptation to harsh winter *** parallel,the selection of cold-tolerant rhizobial strains could allow earlier symbiotic nitrogen(N)fixation to hasten spring regrowth of ***:To identify strains forming nodules rapidly and showing high N-fixing potential,60 rhizobial strains in association with four temperate legume species were evaluated over 11 weeks under spring soil temperatures for kinetics of nodule formation,nitrogenase activity,and host ***:Strains differed in their capacity to form efficient nodules on legume hosts over *** showing higher nitrogenase activity were arctic strain N10 with sainfoin and strain L2 with birdsfoot *** clovers,nitrogenase activity was similar for control and inoculated plants,likely due to formation of effective nodules in controls by endophyte rhizobia present in ***:Selection based on nodulation kinetics at low temperature,nitrogenase activity,and yield was effective to identify performant rhizobial strains for legume *** use of cold-tolerant strains could help mitigate winter climatic changes.

关键词： cold-tolerant rhizobia Lotus corniculatus low temperature Onobrychis viciifolia rhizobium symbiosis Trifolium hybridum Trifolium pratense

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Oxidative dehydrogenation of propane under steady-state and transient regimes over alumina-supported catalysts prepared from mixed V_2W_4O_(19)^(4-) hexametalate precursors

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Journal of Natural Gas Chemistry 2010年第2期19卷 123-133页

作者： Sébastien Paul Elise Berrier Marcia Cristina Kaezer frana jean-Guillaume Eon Univ Lille Nord de france F-59000 LilleFrance ECLille UCCSF-59650 Villeneuve d'AscqFrance CNRS UMR 8181F-59650 Villeneuve d'AscqFrance USTL UCCSF-59650 Villeneuve d'AscqFrance Instituto de Quimíca Universidade Federal do Rio de Janeiro-Cidade UniversitáriaIlha do Fundo21945-970 Rio de JaneiroBrazil

An integrated approach combining the development of an innovative catalyst and the research of a set of adequate operating conditions for the propane oxidative dehydrogenation （OdH） is *** experimental set-up,specially designed for steady-state and transient studies is *** preparation method,the characterization and the performances in steady-state and transient regimes of catalysts based on V2W4O194-Lindqvist isopolyanion used as a precursor and supported on alumina are *** influence of the preparation method of the catalyst and the role of water in the feed gas are more particularly discussed.

关键词： propane oxidative dehydrogenation (OdH) transient regime pulsed reactor Lindqvist isopolyanion in-situ Raman

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