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Differentiation of hMSC in Micromass Culture

生物医学工程学杂志 2005年第S1期22卷 153-154页

作者： Jing-WEI YANG Natalia De ISIA Céline HUSELSTEIN Luc MARCHAL Marie-Nathalie SARDA-KOLOPP Jing-Ping OUYANG jean-fran·ois stol tz Assia ELJAAFARI Research Group of Cell and Tissue Engineering LEMTA-CNRS UMR 7563Facultéde Médecine de NancyUHP and CHU NancyFrance Department of Pathophysiology Medical College of Wuhan UniversityWuhan 430071China Immunology Laboratory Faculty of MedicineUHP Nancy 1Vandoeuvre-lès-NancyFrance

1 Introduction Mesenchymal stem cells(MSCs)are multipotential stem cells which can be expanded in culture while still maintaining their undifferentiated *** have the potential to differentiate into distinct mesenchymal tissue cells,including ***,they are an attrac2 tive cell source for cartilage ti ssue *** vitro high density micromass culture has been widely used for chondrogenesis *** objective of our study was to analyze viability and differentiation of hMSC in micro2 mass cultures.

关键词： stem cells tissue engineering high density

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High-throughput multiplexed fluorescence-activated droplet sorting

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Microsystems & Nanoengineering 2018年第1期4卷 95-104页

作者： Ouriel Caen Simon Schütz M.S.Suryateja Jammalamadaka Jérémy Vrignon Philippe Nizard Tobias M.Schneider jean-Christophe Baret Valérie Taly INSERM UMR-S1147 CNRS SNC5014Paris Descartes UniversityEquipe labellisée Ligue Nationale contre le cancerParisFrance Emergent Complexity in Physical Systems Laboratory(ECPS) Ecole Polytechnique Fédérale de Lausanne1015 LausanneSwitzerland CNRS University BordeauxCRPPUMR 5031115 Avenue Schweitzer33600 PessacFrance

Fluorescence-activated droplet sorting(FADS)is one of the most important features provided by droplet-based ***,to date,it does not allow to compete with the high-throughput multiplexed sorting capabilities offered by flow ***,we demonstrate the use of a dielectrophoretic-based FADS,allowing to sort up to five different droplet populations *** system provides means to select droplets of different phenotypes in a single experimental run to separate initially heterogeneous *** experimental results are rationalized with the help of a numerical model of the actuation of droplets in electric fields providing guidelines for the prediction of sorting designs for upscaled or downscaled microsystems.

关键词： rational initially sorting

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Construction of an Unusual Two-Dimensional Layered Structure for Fused-Ring Energetic Materials with High Energy and Good Stability

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Engineering 2020年第9期6卷 1136-1143页

作者： Yongan Feng Mucong Deng Siwei Song Sitong Chen Qinghua Zhang jean’ne M.Shreeve Department of Chemistry University of IdahoMoscowID 83844-2343USA Institute of Chemical Materials China Academy of Engineering PhysicsMianyang 621900China

制造具有良好机械感度的高性能含能材料在过去几十年里一直是一项重大挑战,因为这类蕴含巨大能量的材料存在内在的不稳定性。本文研究了一种极具潜力的稠环含能材料:4-硝基-7-叠氮基-吡唑-[3,4-d]-1,2,3-三嗪-2-氧(NAPTO)。这种物质具... 详细信息

制造具有良好机械感度的高性能含能材料在过去几十年里一直是一项重大挑战,因为这类蕴含巨大能量的材料存在内在的不稳定性。本文研究了一种极具潜力的稠环含能材料:4-硝基-7-叠氮基-吡唑-[3,4-d]-1,2,3-三嗪-2-氧(NAPTO)。这种物质具有不同寻常的二维(2D)层状结构,其绝对结构已经单晶X射线衍射证实。研究显示,这一结构新颖的含能物质具有惊人的能量[如爆速(D)高达9.12 km·s^-1,爆压(P)为35.1 GPa]、优异的机械感度[撞击感度(IS)为18 J、摩擦感度(FS)为325 N、静电感度(EDS)为0.32 J]和良好的热分解温度(203.2℃),展示出高能量与低感度的双重优势。据我们所知,NAPTO是首个具有二维层状结构的稠环含能材料。与此同时,运用分子模拟分析了其在外界机械刺激下的稳定机制,结果表明,该含能材料超平的二维层状结构比其他结构更能有效地缓冲外界机械刺激,从而将作用在材料上的机械能转化为晶体的层间滑动与压缩。本研究从实验和理论两个方面揭示了稠环二维层状结构在制造先进含能材料方面的巨大潜力。

关键词：含能材料稠环杂环化合物二维层状结构高能量稳定性感度

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Observatory science with eXTP

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Science China(Physics,Mechanics & Astronomy) 2019年第2期62卷 97-138页

作者： jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig SRON Netherlands Institute for Space Research Department of Astronomy University of Geneva Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of Sciences School of Astronomy and Space Science Nanjing University INAF-IASF Bologna ASI Via del Politecnico snc INAF-Istituto di Astrofisica e Planetologie Spaziali Institut für Astronomie und Astrophysik Tübingen Universit?t Tübingen NASA Goddard Space Flight Center ICREA&Institute of Space Sciences(IEEC-CSIC) Campus UABCarrer de Can Magrans CSPAR SPA University of Alabama in Huntsville Department of Physics Texas Tech University INAF Osservatorio Astronomico di Capodimonte Leiden Observatory Leiden University Anton Pannekoek Institute University of Amsterdam ASTRON Netherlands Institute for Radio Astronomy Universitat Politecnica de Catalunya(UPC-IEEC) Universitádegli Studi di Urbino‘Carlo Bo’ Max-Planck-Institut für Radioastronomie Dr.Karl-Remeis-Sternwarte and Erlangen Centre for Astroparticle Physics(ECAP) Friedrich Alexander Universit?t Erlangen-Nurnberg Purple Mountain Observatory Chinese Academy of Sciences Instituto de Astrofysíca de Andalucia-CSIC Department of Physics and Astronomy University of Southampton IRAP Universitéde ToulouseCNRSUPSCNES Mathematical Sciences and STAG Research Centre University of Southampton New York University Abu Dhabi Center for Relativistic Astrophysics School of PhysicsGeorgia Institute of Technology Physics Department Middle East Technical University Department of Physics Technion-Israel Institute of Technology INAF Osservatorio Astronomico di Brera Tata Institute of Fundamental Research Dipartimento di Matematica e Fisica Universitàdegli Studi Roma Tre Instituto de Astrofísica de Canarias Instituto Nacional de Pesquisas Espaciais-INPE National Space Institute Technical University of Denmark(DTU Space) Department of Physics and Astronomy Michigan State University INAF Osservatorio Astrofisico di Arcetri Dipartimento di Fisica Universitádegli Studi di Cagliari Department of Physics and A

In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s.

关键词： space research in struments nuclear astrophysics flare stars accretion and accretion disks mass loss and stellar winds cataclysmic binaries X-ray binaries supernova remnants active galactic nuclei X-ray bursts gamma-ray bursts gravitational waves

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