检索结果-南通市图书馆

Food and Nutrition Sciences 2013年第6期4卷 626-631页

作者： Clément Saidou Robert Ndjouenkeu denis Roux jean Bosco Tchatchueng Alain Heyraud Nadia El Kissi Départment of Applied University of Ngaoundéré Ngaoundéré Camer- oon Départment of Food Sciences & Nutrition University of Ngaoundéré Ngaoundéré Cameroon Laboratory of Rheology University of Joseph Fourier Grenoble University Grenoble France Laboratory of Function and Structure of Polysaccharids Center of Vegetables Macromolecules Research Grenoble France Laboratory of Rheology University of Joseph Fourier Grenoble University Grenoble France

Triumfetta cordifolia and Bridelia thermifolia are two shrubs from tropical region of Africa. Their gums are traditionally extracted from fresh barks and used in traditional recipes (thickening and aromatization of sauces, improvement of the swelling of maize and bean cakes) and in the process of decantation of traditional beer. In order to valorize these barks in dried form, study of the effect of drying temperature on the rheological properties of their gums was carried out. In this respect, the fresh barks were dried at 40℃, 50℃, 60℃, 70℃ and 80℃ and the viscosity of their extracts was measured. The drying kinetic of the barks showed two falling rate periods represented by two drying constants?k1 and k2. The absolute viscosity of the extracts decreased beyond drying temperatures higher than 70℃ and 80℃respectively for T cordifolia and B. Thermifolia. The decreasing viscosity is attributed mainly to a reorganization of polysaccharide chains. The temperatures range lower than 70℃ could be retained to dry the barks and to extract gums without deteriorating their properties.

关键词： Barks Drying Constant Equilibrium Moisture Content Gums Viscosity

Interventional radiology therapies for liver cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatoma Research 2016年第1期2卷 1-9页

作者： Romaric Loffroy Louis Estivalet Sylvain Favelier Pierre Pottecher Pierre-Yves Genson jean-Pierre Cercueil denis Krause Department of Vascular Oncologic and Interventional RadiologyLe2i UMR CNRS 6306University of Dijon School of MedicineBocage Teaching Hospital21079 Dijon CedexFrance

Hepatocellular carcinoma(HCC)is the fifth most frequently found primary malignant tumor in the *** surgery and liver transplantation are considered optimal for the curative treatment of ***,only 15-20%of HCCs may be surgically *** of the surgically-non-eligible patients have to receive locoregional image-guided interventional treatments including intra-arterial and percutaneous ablative *** goal of this paper is to review these interventional oncology *** therapeutic approaches include chemical therapies(such as ethanol or acetic acid injection),and thermal therapies(such as radiofrequency ablation,laser-induced thermotherapy,microwave ablation,cryoablation,and high-intensity focused ultrasound ablation).Catheter-based therapies include embolotherapy/chemotherapy-based treatments(such as transcatheter arterial chemoembolization,bland embolization,transcatheter arterial chemoinfusion,and chemoembolization with drug-eluting beads),and radiotherapy-based treatments(such as radioembolization with yttrium-90 and injection of iodine-131-labeled lipiodol).As a result of the technical development of locoregional approaches for HCC during the recent decades,the range of combined interventional therapies has been continuously *** this article,an evidence-based approach will be used to review the current role of interventional radiology therapies in the management of unresectable HCC.

关键词： Hepatocellular carcinoma local ablative therapy radioembolization transarterial chemoembolization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

用于敞开式变电站的特高压开关设备

华东电力 2007年第C期35卷 104-113页

作者： Francois Biquez denis Chatrefou jean-Marie Delcoustal Ferruccio Dianin Christian Lindner Raoul Piccoli AREVA T&D France

作为1100kV的UHV（特高压）输电，面临技术——生态环境的巨大挑战。变电站的UHV开关装置模块，需要的是可靠、成本／效益比好、环境友好、可维护的方案。对于这些所需的参数以及技术规范的验证，采用AIS（空气隔离变电所）技术能完全... 详细信息

作为1100kV的UHV（特高压）输电，面临技术——生态环境的巨大挑战。变电站的UHV开关装置模块，需要的是可靠、成本／效益比好、环境友好、可维护的方案。对于这些所需的参数以及技术规范的验证，采用AIS（空气隔离变电所）技术能完全满足这些需要。介绍由瓷柱式断路器、隔离开关和NCIT（非传统互感器）所组成的UHV模块。这些装置是根据模块原理预先设计好的，其中的设备间的连接肯定允许快速安装。在变电站设备控制和检测方面，模块是预制标准化。加拿大和德国的试验站对断路器、隔离开关等独立的开关元件，在1100kV上做BIL、SIL和工频等绝缘试验，性能表现非常优越。因为对于特高压电压等级，IEC标准至今尚未规定，所以将根据外推法和现场数据作合理解释。瓷柱式断路器采用了最新复合绝缘体技术，在安全方面有所改进。AIS方案其他的关键技术，例如环境保护和成本，在可比的功能间，根据市场估计价值，与GIS解决方法作了比较。

关键词：特高压敞开式变电站开关设备

Transcatheter embolization as the new reference standard for endoscopically unmanageable upper gastrointestinal bleeding

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Surgery 2012年第10期4卷 223-227页

作者： Romaric Loffroy Louis Estivalet Violaine Cherblanc Damien Sottier Boris Guiu jean-Pierre Cercueil denis Krausé Department of Vascular and Interventional Radiology University of Dijon School of MedicineBocage Teaching Hospital21079 Dijon CedexFrance

Acute nonvariceal upper gastrointestinal bleeding(UGIB) is a major medical emergency problem associated with significant morbidity and *** is considered the first method of choice to detect and treat *** therapy usually achieves primary hemostasis,but 10%-30% of these patients have repeat *** patients in whom hemostasis is not achieved with endoscopic techniques,treatment with transcatheter angiographic embolization(TAE) or surgery is *** intervention is usually an expeditious and gratifying endeavor,but it can be associated with high operative mortality rates.A large number of studies support the use of TAE as salvage therapy as an alternative to ***,few studies have compared the results of TAE with that of emergency surgery in terms of efficiency,the frequency of repeat bleeding,and ***,Ang et al retrospectively compared the outcome of TAE and surgery as salvage therapy of UGIB after failed endoscopic *** were no significant differences in 30 d mortality,complication rates and length of stay although higher rebleeding rates were observed after TAE compared with *** this commentary,we discuss the advantages and drawbacks of these two therapeutic strategies for *** also attempt to define the exact role of TAE for acute nonvariceal UGIB.

关键词： Upper gastrointestinal bleeding Endoscopic hemostasis Transcatheter embolization Surgery

Endovascular Repair of an Infected Broken Pseudoaneurysm of the Extracranial Internal Carotid Artery

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Radiology 2012年第4期2卷 113-116页

作者： Claude Michel Alain Parot Patrick Jue denis Pierre-Yves Laffy jean-Yves Riou Gilbert Leblanc Cardio-Vascular Radiology Department Marie Lannelongue Hospital Le Plessis Robinson France Vascular Radiology Department Europe Medico-Surgical Center Le Port Marly France Vascular Surgery Department Europe Medico-Surgical Center Le Port Marly France

The formation of pseudoaneurysms after carotid endarterectomy is extremely rare. Treating those pseudoaneuryms is necessary because of the risks for continued expansion, rupture and distal embolism. Traditional surgical repair of carotid artery pseudoaneurysms is associated with a high morbidity and mortality. An endovascular approach to these infected pseudoaneurysms limits the risk for operative damage to surrounding structures and potential blood loss.

关键词： Carotid Artery Pseudoaneurysm Covered Self Expandable Stent

SesIndexCreatoR:An R Package for Socioeconomic Indices Computation and Visualization

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Statistics 2015年第4期5卷 291-302页

作者： Benoit Lalloue Severine Deguen jean-Marie Monnez Cindy Padilla Wahida Kihal denis Zmirou-Navier Nolwenn Le Meur Institut Gustave Roussy ParisFrance EHESP Rennes Sorbonne Paris CiteRennesFrance Inserm UMR IRSETInstitut de recherche sur la sante l’environnement et le travail-1085RennesFrance Lorraine University CNRSINRIA UMR 7502Institut Elie CartanLorraineFrance Lorraine University Medical SchoolLorraineFrance

In order to study social inequalities, indices can be used to summarize the multiple dimensions of the socioeconomic status. As a part of the Equit’Area Project, a public health program focused on social and environmental health inequalities;a statistical procedure to create (neighborhood) socioeconomic indices was developed. This procedure uses successive principal components analyses to select variables and create the index. In order to simplify the application of the procedure for non-specialists, the R package SesIndexCreatoR was created. It allows the creation of the index with all the possible options of the procedure, the classification of the resulting index in categories using several classical methods, the visualization of the results, and the generation of automatic reports.

关键词： Socioeconomic Status Multidimensional Index Principal Component Analysis Hierarchical Classification R

Endovascular management of visceral artery aneurysms: When to watch, when to intervene?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Radiology 2015年第7期7卷 143-148页

作者： Romaric Loffroy Sylvain Favelier Pierre Pottecher Pierre-Yves Genson Louis Estivalet Sophie Gehin jean-Pierre Cercueil denis Krausé Department of Vascular Oncologic and Interventional Radiology University of Dijon School of Medicine Bocage Teaching Hospital

Visceral artery aneurysms(VAA) include splanchnic and renal artery aneurysms. They represent a rare clinical entity, although their detection is rising due to an increased use of cross-sectional imaging. Rupture is the most devastating complication, and is associated with a high morbidity and mortality. In addition, increased percutaneous endovascular interventions have raised the incidence of iatrogenic visceral artery pseudoaneurysms(VAPAs). For this reason, elective repair is preferable in the appropriately chosen patient. Controversy still exists regarding their treatment. Over the past decade, there has been steady increase in the utilization of minimally invasive, non-operative interventions, for vascular aneurysmal disease. All VAAs and VAPAs can technically be fixed by endovascular techniques but that does not mean they should. These catheter-based techniques constitute an excellent approach in the elective setting. However, in the emergent setting it may carry a higher morbidity and mortality. The decision for intervention has to take into account the size and the natural history of the lesion, the risk of rupture, which is high during pregnancy, and the relative risk of surgical or radiological intervention. For splanchnic artery aneurysms, we should recognize that we are not, in reality, well informed about their natural history. For most asymptomatic aneurysms, expectant treatment is acceptable. For large, symptomatic or aneurysms with a high risk of rupture, endovascular treatment has become the firstline therapy. Treatment of VAPAs is always mandatory because of the high risk of rupture. We present our point of view on interventional radiology in the splanchnic arteries, focusing on what has been achieved and the remaining challenges.

关键词： Visceral artery Aneurysm False aneurysm Angiography Embolization Stent-graft

Molecular mechanisms of liver carcinogenesis related to metabolic syndrome

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatoma Research 2022年第1期8卷 22-34页

作者： Claudia Campani jean-Charles Nault Team of Functional Genomics of Solid Tumors Centre de Recherche des CordeliersSorbonne UniversitéInsermUniversitéde ParisParis F-75006France Equipe labellisée Ligue Nationale Contre le Cancer Labex OncoImmunologyParis F-75006France Department of Experimental and Clinical Medicine University of FlorenceFlorence 50139Italy Service d’hépatologie Hôpital AvicenneHôpitaux Universitaires Paris-Seine-Saint-DenisAssistance-Publique Hôpitaux de ParisBobigny 93000France Unitéde Formation et de Recherche SantéMédecine et Biologie Humaine UniversitéParis 13Communautéd’Universités et Etablissements Sorbonne Paris CitéBobigny 93000France

Global prevalence of non-alcoholic fatty liver disease(NAFLD)and of NAFLD-hepatocellular carcinoma(HCC)is estimated to grow in the next *** burden of NAFLD and the evidence that NAFLD-HCC arises also in noncirrhotic patients,explain the urgent need of a better characterization of the molecular mechanisms involved in NAFLD *** and diabetes cause a chronic inflammatory state which favors changes in serum cytokines and adipokines,an increase in oxidative stress,DNA damage,and the activation of multiple signaling pathways involved in cell ***,a role in promoting NAFLD-HCC has been highlighted in the innate and adaptive immune system,dysbiosis,and alterations in bile acids *** dietary,genetic,or combined mouse models have been used to study nonalcoholic steatohepatitis(NASH)development and its progression to HCC,but models that fully recapitulate the biological and prognostic features of human NASH are still *** humans,four single nucleotide polymorphisms(PNPLA3,TM6SF2,GCKR,and MBOAT7)have been linked to the development of both NASH and HCC in cirrhotic and non-cirrhotic patients,whereas HSD17B13 polymorphism has a protective *** addition,higher rates of somatic ACVR2A mutations and a novel mutational signature have been recently discovered in NASH-HCC *** knowledge of the molecular pathogenesis of NAFLD-HCC will be helpful to personalized screening programs and allow for primary and secondary chemopreventive treatments for NAFLD patients who are more likely to progress to HCC.

关键词： Hepatocellular carcinoma mouse model genetic predisposition cirrhosis non-alcoholic fatty liver disease immune system

Systemic treatment of hepatocellular carcinoma:the times they are a-changin’

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hepatobiliary Surgery and Nutrition 2021年第6期10卷 893-895页

作者： Claudia Campani jean-Charles Nault Centre de Recherche des Cordeliers Sorbonne UniversitéInsermUniversitéde ParisTeam“Functional Genomics of Solid Tumors”ParisFrance Equipe labellisée Ligue Nationale Contre le Cancer Labex OncoImmunologyParisFrance Department of Experimental and Clinical Medicine University of FlorenceFlorenceItaly Service d’Hépatologie Hôpital AvicenneHôpitaux Universitaires Paris-Seine-Saint-DenisAssistance-Publique Hôpitaux de ParisBobignyFrance Unitéde Formation et de Recherche SantéMédecine et Biologie Humaine UniversitéParis 13Communautéd’Universités et Etablissements Sorbonne Paris CitéParisFrance

For a decade,sorafenib remained the only drug approved for the treatment of advanced hepatocellular carcinoma(HCC)due to the failure of several phase III trials in which alternative angiogenesis inhibitors were tested(1).In recent years,the field of systemic treatments of HCC has evolved quickly and a recent position paper of the European Association for the Study of the Liver has well described the current advances in the systemic treatment of advanced HCC as well as the unmet needs in the field(1).First,lenvatinib was approved as an alternative to sorafenib in the first-line setting,and,thus,regorafenib,cabozantinib and ramucirumab as second-line treatments for patients who progressed on sorafenib(1).

关键词： hepatocellular treatment Liver

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

一顿法餐的秘密

世界 2008年第9期 147-153页

作者：东田 denis Rouvre jean Francois Pieg

法国美食教皇Bocuse曾说“食欲和性欲一样”。其实，我倒是觉得法国人对美食的热情和执著远远胜过于他们对待情人：法国人可以为了在心仪的餐厅里占据一张桌子，提前半年来预订，经过半年的耐心等待，在某个晚上，盛装赴约。

关键词：秘密法国人美食教皇执著