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极地冰芯中的火山活动记录与全球气候环境变化研究

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极地冰芯中的火山活动记录与全球气候环境变化研究

Major Limb Amputation Secondary to Locally Advanced Cutaneous Squamous Cell Carcinoma in Tropical Environments: Determinants

中国地球物理学会第十八届年会

作者：刘雷保 jean robert Petit Martinede Angelis 康建成中国极地研究所 Laboratoire de Glaciologie et Geophysique de 1Environnement BP96F-38402CNRSFrance Laboratoire de Glaciologie et Geophysique de 1Environnement BP96F-38402CNRSFrance 中国极地研究所

＜正＞自从Hammer等人（1980）在格陵兰冰芯中,开创性地开展火山活动记录研究以来,许多学者相继在极地地区开展了该方面工作,以评价火山活动对全球气候环境及生态系统的影响,如Zielinski等对北极格陵兰GISP2冰芯、***等对南极冰盖220...

＜正＞自从Hammer等人（1980）在格陵兰冰芯中,开创性地开展火山活动记录研究以来,许多学者相继在极地地区开展了该方面工作,以评价火山活动对全球气候环境及生态系统的影响,如Zielinski等对北极格陵兰GISP2冰芯、***等对南极冰盖220年来火山源硫酸根记录研究,robert ***等对南极冰芯中1000年火山喷发记录、Jihong Cole—Dai等对东南极4100年来火山喷发记录研究等等,不一而足。本文主要报道对南极东方站Vostok冰芯中距今4724年的一次比较大的火山事件精细研究成果,以丰富该领域的研究内容。

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Open Journal of Orthopedics 2018年第4期8卷 139-147页

作者： Kouassi Kouamé jean Eric Yao Loukou Blaise Sery Bada Justin Leopold Niaoré M’bra Kouamé Innocent Krah Koffi Léopold Kouassi Aya Adelaide Nathacha Assere Yao Aboh Ganyn robert Arnaud Kodo Michel Trauma and Orthopedics Department Bouake Teaching Hospital Bouake Ivory Coast

Objective: To identify the determinants of secondary limb amputation in advanced squamous cell carcinoma. Material and Methods: This was a retrospective study carried out in the Orthopedic Traumatology Department of the Bouaké University Hospital in Côte d’Ivoire from January 2013 to December 2016. It involved ten patients with locally advanced skin squamous cell carcinoma, confirmed by histology and having amputated limbs. The parameters studied were: demographic data (gender, age), socio-economic conditions (occupation, place of residence), the risk factors involved, the use of topical self-medication and the use of traditional medicine, antecedents and comorbidities factors, lifestyle, clinical aspects (seat, size), extension assessment (X-ray), anatomo-pathological examination data, duration of evolution of squamous cell carcinoma, the function of the affected limb, the treatment performed, the evolutionary modalities and the equipment. Results: Between 2013 and 2016, ten patients underwent either upper or lower limb amputations following locally advanced squamous cell carcinoma. The average age was 34.1 years (19 - 64 years). There were 7 men (70%) and 3 women (30%) and all our patients were black (sub-Saharan Africa). The majority of our patients were farmers (70%). The risk factors for squamous cell carcinoma were neglected chronic wounds. All our patients recognized during the interrogation a large use of the topicals of traditional medicine for the treatment of the initial cutaneous lesions. In terms of lifestyle, five (50%) were smokers and alcoholics. The mean time to progression of squamous cell carcinoma was 5.9 years. Lesions were localized preferentially to the pelvic limbs six (60%) cases and four (40%) to the limbs chest. The lesion was diagnosed late in all our patients. The size of the tumor in all our patients was greater than 5 cm and had a deep invasion (nerves, vessels and bone). The proximal ipsilateral ganglionic invasion was constant.

关键词： Amputation Squamous Cell Carcinoma Cutaneous Histology

Madelung’s Deformity: Reverse Wedge Osteotomy of the Distal Radius Associate Ulnar Wedge Osteotomy: A Case Report

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Open Journal of Orthopedics 2018年第2期8卷 33-38页

作者： Kouassi Kouamé jean Eric Sery Bada Justin Leopoeld Niaoré Yao Loukou Blaise M’bra Kouame Innocent Krah Koffi Léopold Kouassi Aya Adelaide Nathacha Assere Yao Aboh Ganyn robert Arnaud Kodo Michel Traumatology and Orthopedics Surgery of the University Hospital of Bouake Bouake Cote d’Ivoire

Madelung deformity is rare, accounting for 1.7% of congenital anomalies. The treatment is essentially surgical and several techniques have been described. We report the result of a case treated in an adult patient by ... 详细信息

关键词： Madelung Deformity Cuneiform Osteotomy Radius Ulna

Gastroschisis Associated with Cleft Lip and Palate: Report of Three Cases

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Open Journal of Pediatrics 2019年第1期9卷 1-6页

作者： Kouamé Soroboua Agbara Martial Olivier Moulot Adjoba Manuela Ehua jean Marie Konan Ibrahim Traoré Franck Grah Anon Ghislain Anon Josaphat Konvolbo robert Boulleys Idalia Ajoumissi Alphamoyé Haidara Paule-Christine Ekobo Sanni Roumanatou Bankolé Félix Houpouet Boigny University Cocody/Abidjan Ivory Coast

Gastroschisis is a malformation of the abdominal wall like omphalocele. In most cases, gastroschisis is isolated. But in some cases, we find malformations, essentially minor and concern gastrointestinal or genitourinary systems. Association with craniofacial congenital midline defects is uncommon. We report 3 cases of association between gastroschisis and cleft lip and palate for the benefit of the scientific community. Two 0-day-old and a 1-day newborns were admitted in our institution for malformation of face and abdominal wall. The physical examination confirmed the association of gastroschisis and cleft lip and palate. The patients underwent primary closure. Other malformations could not be sought until all patients died.

关键词： Gastroschisis Cleft Lip and Palate Primary Closure

Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses:A multicenter study

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World Journal of Gastroenterology 2009年第13期15卷 1587-1593页

作者： Marc Giovannini Botelberge Thomas Bories Erwan Pesenti Christian Caillol Fabrice Esterni Benjamin Monges Geneviève Arcidiacono Paolo Deprez Pierre Yeung robert Schimdt Walter Schrader Hanz Szymanski Carl Dietrich Christoph Eisendrath Pierre Van Laethem jean-Luc Devière Jacques Vilmann Peter Saftoiu Andrian Endoscopy Unit Paoli-Calmettes Institute Department of Pathology Paoli-Calmettes Institute Endosonography Unit Gastroenterology and Gastrointestinal Endoscopy UnitSan Raffaele Hospital Division of Gastroenterology University Hospital Saint-Luc Department of MedicineⅠ University Hospital Department of Internal Medicine 2 Caritas-KrankenhausBad Mergentheim Division of Gastroenterology Erasme Hospital Department of Surgical Gastroenterology Gentofte University Hospital

AIM:To evaluate the ability of endoscopic ultrasound(EUS) elastography to distinguish benign from malignant pancreatic masses and lymph ***:A multicenter study was conducted and included 222 patients who underwent EUS examination with assessment of a pancreatic mass(n=121) or lymph node(n=101).The classification as benign or malignant,based on the real time elastography pattern,was compared with the classif ication based on the B-mode EUS images and with the fi nal diagnosis obtained by EUS-guided fi ne needle aspiration(EUS-FNA) and/or by surgical *** interobserver study was ***:The sensitivity and specificity of EUS elastography to differentiate benign from malignant pancreatic lesions are 92.3% and 80.0%,respectively,compared to 92.3% and 68.9%,respectively,for the conventional B-mode *** sensitivity and specificity of EUS elastography to differentiate benign from malignant lymph nodes was 91.8% and 82.5%,respectively,compared to 78.6% and 50.0%,respectively,for the B-mode *** kappa coefficient was 0.785 for the pancreatic masses and 0.657 for the lymph ***:EUS elastography is superior compared to conventional B-mode imaging and appears to be able to distinguish benign from malignant pancreatic masses and lymph nodes with a high sensitivity,specificity and *** might be reserved as a second line examination to help characterise pancreatic masses after negative EUS-FNA and might increase the yield of EUS-FNA for lymph nodes.

关键词： Endoscopic ultrasound Elasticity coefficient Elastography Pancreatic mass Lymph node

Towards Mutuality in the Canada-China Relationship:The Experience of the Department of Surgery at Laval University since the 1980s

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Frontiers of Education in China 2015年第3期10卷 384-400页

作者： robert GUIDOIN WANG Lu Yvan DOUVILLE Department of Surgery Faculty of MedicineLaval UniversityQuebec CityQuebec G1V 0A6Canada Key Laboratory of Textile Science and Technology of Ministry of Education College of TextilesDonghua UniversityShanghai 200051China

The Department of Surgery at Laval University has been a key player in the development of Canada-China cooperation since the *** projects initiated and developed by jean Couture and Guojin Liu to address cancer issues,and specifically breast cancer,were heralded as outstanding *** the meantime,the Department of Surgery at Laval University trained numerous Chinese scholars,students,and post-doctoral fellows who became leaders in their fields of expertise.A few of these scholars and students settled in Canada,but the vast majority returned *** 2007,a highly specialized research program related to surgical implants with the College of Textiles at Donghua University has been opening new avenues in medical textiles to develop expertise through student training,to launch bridges between textile engineers and clinicians,and to provide the industry with a unique *** final goal is to improve the accessibility and affordability of health care delivery in both Canada and *** is now a key player in related research and no longer requires foreign *** it can easily find multiple partners,Canada must be alert to building on its legacy and maintaining its privileged *** is now a place for Canadian champions.

关键词： Canada-China cooperation mutuality Changchun Laval University Donghua University

Interdialytic 24-Hours Ambulatory Blood Pressure versus Dialysis Unit Blood Pressure for the Diagnosis of Electrocardiographic-Left Ventricular Hypertrophy in Chronic Hemodialysis Black Patients

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World Journal of Cardiovascular Diseases 2019年第11期9卷 846-856页

作者： Cédric Kabemba Ilunga Francois Bompeka Beka Lepira jean robert Rissassi Makulo Yves Lubenga Trésor Mvunzi Noel Utshudi Aliocha Nkodila Vieux Momeme Mokoli Ernest Kiswaya Sumaili Nazaire Mangani Nseka Eleuthère Vita Kintoki Division of Nephrology Department of Internal MedicineUniversity of Kinshasa HospitalKinshasathe Democratic Republic of the Congo Division of Cardiology Department of Internal MedicineUniversity of Kinshasa HospitalKinshasathe Democratic Republic of the Congo Centre medical cite des Aveugles KinshasaCongo

Background and Aim: In hemodialysis patients, 24-hours interdialytic ABPM better detects TOD than dialysis unit blood pressure. Therefore, the present study was aimed to assess the diagnostic performance of 24-hours ABPM vs. dialysis unit BPs for the diagnosis of ECG-LVH in steady state chronic hemodialysis black patients. Methods: From March 31 to September 30, 2018, interdialytic ABPM was performed after a mid-week hemodialysis session for 24 hours using a Spacelab 90207 ABPM monitor in the non-access arm in 45 stable chronic hemodialysis black patients (age ≥ 20 years, hemodialysis for at least 3 months and informed consent) attending 3 hemodialysis centers in Kinshasa. Ambulatory BP was recorded every 20 minutes during the day (6 AM to 10 PM) and every 30 minutes during the night (10 PM to 6 AM). ECG-LVH was defined using Cornell product criteria. ROC curve method was used to assess the performance of dialysis unit BPs vs. interdialytic 24-hours ABPM in diagnosing ECG-LVH. P 0.05 defined the level of statistical significance. Results: Whatever the method of BP measurement, all the SBP values were related to ECG-LVH with similar AUC and overlapping 95% CI;however, they were not significantly different from each other. 24-hours interdialytic ambulatory SBP (AUC 0.748;95% CI 0.58 - 0.94) had the highest area under the curve. Conclusion: The present study showed that although all the two BP measurement methods equally detected ECG-LVH, 24-hours ABPM tended to have the highest diagnostic performance.

关键词： 24-Hours ABPM Dialysis Unit BPs ECG-LVH Diagnostic Performance Chronic Hemodialysis Black Africans

法国地球透镜计划(GEOSCOPE):过去30年的进展与挑战

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国际地震动态 2010年第12期31卷 6-37页

作者： Geneviève Roult jean-Paul Montagner Barbara Romanowicz Michel Cara Daniel Rouland robert Pillet jean-Franois Karczewski Luis Rivera Eléonore Stutzmann Alessia Maggi 左玉玲 Institut de Physique du Globe Paris Berkeley Seismological Laboratory BerkeleyCalifornia Ecole et Observatoire des Sciences de la Terre StrasbourgFrance Géosciences Azur Université de Nice-Sophia AntipolisNiceFrance 中国地震局地球物理研究所

1长周期地震学的早期概况巴黎地球物理学院(Institut de Phy-sique du Globe in Paris,简称IPGP)在长周期地震学和观测设施方面有着雄厚的基础。该学院的地震实验室于1952—1982年设计了人工操作的地震仪,主要用于对固体潮倾斜的研究。... 详细信息

1长周期地震学的早期概况巴黎地球物理学院(Institut de Phy-sique du Globe in Paris,简称IPGP)在长周期地震学和观测设施方面有着雄厚的基础。该学院的地震实验室于1952—1982年设计了人工操作的地震仪,主要用于对固体潮倾斜的研究。经过多次尝试,Blum等[1-2]在1957年终于研制出了第一台原型倾斜仪。这一传感器是一台传统的措尔纳(Z llner)悬挂式[3]水平向机械地震仪,由熔融石英制成,在真空环境下工作(图1a)。它采用的是光放大和摄影记录技术,速度为1cm/h。当时,在记录线变粗时就认为出现了地震。然而,1960年5月22日智利大地震的记录中

关键词：地球透镜计划法国物理学院地震学观测设施人工操作长周期地震仪

Adult human liver slice cultures:Modelling of liver fibrosis and evaluation of new anti-fibrotic drugs

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World Journal of Hepatology 2021年第2期13卷 187-217页

作者： Daria Kartasheva-Ebertz Jesintha Gaston Loriane Lair-Mehiri Pierre-Philippe Massault Olivier Scatton jean-Christophe Vaillant Vladimir Alexei Morozov Stanislas Pol Sylvie Lagaye Institut Pasteur Immunobiologie des Cellules DendritiquesINSERM U1223Paris 75015France BioSPC Universitéde ParisParis 75005France Service de Chirurgie digestive Hépato-biliaire et EndocrinienneAPHPGroupe Hospitalier CochinParis 75014France Service de Chirurgie digestive et Hépato bilio pancréatique AP-HPGroupe Hospitalier La Pitié-SalpétrièreMedecine Sorbonne UniversitéParis 75013France Center for HIV and Retrovirology Department of Infectious DiseasesRobert Koch InstituteBerlin 13353Germany Département d'Hépatologie AP-HPGroupe Hospitalier CochinUniversitéde ParisParis 75014France

BACKGROUND Liver fibrosis can result in end-stage liver failure and *** To examine human liver fibrogenesis and anti-fibrotic therapies,we evaluated the three dimensional ex vivo liver slice(LS)*** Fibrotic liver samples(F0 to F4 fibrosis stage according to the METAVIR score)were collected from patients after liver *** liver slices(HLS)were cultivated for up to 21 *** C virus(HCV)infection,alcohol(ethanol stimulation)and steatosis(palmitate stimulation)were examined in fibrotic(F2 to F4)liver slices infected(or not)with HCV.F0-F1 HLS were used as *** day 0,either ursodeoxycholic acid(choleretic and hepatoprotective properties)and/or α-tocopherol(antioxidant properties)were added to standard of care on HLS and fibrotic liver slices,infected(or not)with *** of the biomarkers of fibrosis and the triglyceride production were checked by quantitative reverse transcription polymerase chain reaction and/or enzymelinked immunosorbent *** The cultures were viable in vitro for 21 days allowing to study fibrosis inducers and to estimate the effect of anti-fibrotic *** of the biomarkers of fibrosis and the progression to steatosis(estimated by triglycerides production)was increased with the addition of HCV and/or ethanol or *** day 15 of the follow-up studies,a significant decrease of both transforming growth factorβ-1 and Procol1A1 expression and triglycerides production was observed when a combined anti-fibrotic treatment was applied on HCV infected F2-F4 LS *** These results show that the human three dimensional ex vivo model effectively reflects the in vivo processes in damaged human liver(viral,alcoholic,nonalcoholic steatohepatitis liver diseases)and provides the proof of concept that the LS examined model permits a rapid evaluation of new anti-fibrotic therapies when used alone or in combination.

关键词： Human liver fibrosis Hepatitis C virus Alcoholic liver disease Nonalcoholic steatohepatitis Ex vivo model Drugs