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A Pilot Study about the First Cases of Coronary Angioplasty in Democratic Republic of Congo/Kinshasa: Patient Profile

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Case Reports in Clinical medicine 2023年第10期12卷 371-388页

作者： David Ipungu Gondele Eulethère Vita Kintoki Yves Lubenga Georges Ngoyi Trésor mvunzi Dominique mupepe Nathan Buila Zéphirin Kamuanga Fahd Qureshi Aliosha Nkodila jean Robert Rissasi makulo jean rené m’buyamba-kabangu Cardiology Unit University of Kinshasa Hospital Kinshasa The Democratic Republic of Congo Cardiology Unit Centre Hospitalier Victor Dupouy Argenteuil France Cardiology Unit H.J. Hospitals Kinshasa The Democratic Republic of Congo Public Health and Familly medecine Protestant University of Congo Kinshasa The Democratic Republic of Congo Nephrology Unit University of Kinshasa Hospital Kinshasa The Democratic Republic of Congo

Background: The objective of this pilot study was to describe clinical profile, electric, echocardiographic and angiographic caracteristics with procedural outcome of congolease patients undergoing coronarography in the first and only one cardiac catheterization center opened in Kinshasa. methods: An analytical cross-sectional study was carried out over a period from October 2019 (date of establishment of the first coronary angiography unit in DR Congo) to march 2021. We proceeded to a serial sampling of the consecutive cases of all the patients who have an angiographic exploration of coronary arteries. Clinical, ECG and cardiac ultrasound data were collected in all patients. The indications for the coronary angiography examination were set by differents cardiologists on the basis of repolarization troubles in the electrocardiogram, cinetic troubles in echocardiography, positive stress test and chest pain in patients with cardiovascular risq factors. Results: The serie (47 patients) was predominantly male with a sex ratio m/W of 2.6. The average age was 59.8 ± 10.5 years. Arterial hypertension (HBP) was the main risk factor (89.4%);followed by diabetes mellitus (14.9%). Chest pain was the main functional sign with an atypical character in 44.7%. The ECG showed ST segment depression (17%) and T wave inversion (17%), the anterior region being the most affected. Hypokinesia was the most common echocardiographic abnormality (34%), followed by akinesia (10.6%). The anteroseptal and apical territories were affected in 12.8%. Dilated myocardiopathy (DmC) was significantly predominant in the male sex (29.4% vs 7.7%;p = 0.011). With radial puncture as the main approach, coronary angiography was pathological in 44% revealing mono-truncal lesions. The left coronary network was the most affected: the middle inter ventricular artery (12.8%), the proximal interventricular artery (10.6%) and the proximal circonflex artery (10.6%). In multivariate logistic regression analysis, age

关键词： Heart Disease Coronary Angioplasty Patient Profile Pilot Study Democratic Republic of Congo

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Lifestyle Changes for Abdominal Obesity Prevention and Encouraging Fruit Consumption may Be Beneficial in Preventing Left Ventricular Hypertrophy in Sub-Saharan African and maghreb

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World Journal of Cardiovascular Diseases 2017年第2期7卷 46-56页

作者： Charifa Annis Bernard Kianu Phanzu Sidibe moussa mustapha El Hattaoui Benzaroual Dounia jean-rené m’buyamba kabangu Benjamin Longo-mbenza Cardiology Unit CHU Mohammed VI Marrakech Kingdom of Morocco Unit of Cardiology University Hospital of Kinshasa Kinshasa Democratic Republic of Congo Faculty of Health Sciences Walter Sisulu University Mthatha Republic of South Africa

There is a growing body of evidence showing a close correlation between left ventricular mass with cardiovascular morbidity and overall mortality. Therefore, identifying the determinants of left ventricular hypertrophy can be of great importance for cardiovascular prevention, for prognosis and therapeutic intervention. Objective: To assess the prevalence and identify the independent determinants of echocardiographic left ventricular hypertrophy in The mA-Ghreb and Sub-Saharan Africa Left-Ventricul ArGEometry Study (mAG-SALVAGES) participants. methods: The mAG-SALVAGES is a community based study in which 100 asymptomatic Black Sub-Saharan African (BSSA) and 189 white skin maghreb within the age of 18 to 55 years underwent a resting echocardiography. multivariate logistic regression analysis was utilized to identify the independent determinants of LVH left ventricular hypertrophy. Results: men represented the majority of the enrolled participants: 173 (59.9%). Echocardiographic left ventricular hypertrophy was seen in 10 (3.5%) participants. Age ≥40 years, female gender, overall obesity, abdominal obesity, hypertension status and less fruit consumption were significantly associated with echocardiography left ventricular hypertrophy. After adjusting for confounding factors, age ≥40 years, female gender, abdominal obesity and less fruit consumption were independently and significantly associated with echocardiographic left ventricular hypertrophy, as illustrated in the following equation: Y = 0.36 + 0.162 age >40 years + 2.69 female gender + 2.52 abdominal obesity + 1.31 less fruit consumption. Conclusion: Lifestyle changes for the prevention of abdominal obesity and encouraging fruit consumption may be beneficial in preventing left ventricular hypertrophy.

关键词： Left Ventricular Hypertrophy Abdominal Obesity Diet Sub-Saharan African maghreb

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mitochondrial recruitment in myelin:an anchor for myelin dynamics and plasticity?

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Neural Regeneration Research 2024年第7期19卷 1401-1402页

作者： jean-David m.Gothié Timothy E.Kennedy Department of Neurology and Neurosurgery Montreal Neurological InstituteMcGill UniversityMontrealQCCanada

Optimal propagation of neuronal electrical impulses depends on the insulation of axons by myelin,produced in the central nervous system by *** is an extension of the oligodendrocyte plasma membrane,which wraps around an axon to form a compact multi-layered *** is composed of a substantially higher proportion of lipids compared to other biological membranes and enriched in a small number of specialized proteins.

关键词： plasticity insulation dynamics

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Bound and Resonating multiquark Configurations

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Chinese Physics Letters 2024年第8期41卷 8-12页

作者： jean-marc Richard Institut de Physique des 2 Infinis de Lyon Universit′e Claude Bernard(Lyon 1) CNRS-IN2P34 rue Enrico Fermi69622 VilleurbanneFrance

We review the predictions of quark models for multiquark configurations that are bound or resonant states,and compare different methods for estimating the properties of resonances.

关键词： quark Configuration resonant

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microplastics and microbiota:Unraveling the hidden environmental challenge

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World Journal of Gastroenterology 2024年第16期30卷 2191-2194页

作者： jean Demarquoy Universitéde Bourgogne Institut Agro-DijonDijon 21000France

This editorial explores the intricate relationship between microplastics(mPs)and gut microbiota,emphasizing the complexity and environmental health *** gut microbiota,a crucial component of gastrointestinal health,is examined in the context of potential microbial degradation of ***,dysbiosis induced by mPs emerges as a consensus,disrupting the balance of gut microbiota and decreasing *** mechanisms triggering dysbiosis,including physical interactions and chemical composition,are under *** research addresses the consequences of mPs on immune function,nutrient metabolism,and overall host *** bidirectional relationship between mPs and gut microbiota has significant implications for environmental and human *** uncertainties,mPs negatively impact gut microbiota and *** research is essential to unravel the complex interactions and assess the long-term consequences of mPs on both environmental and human well-being.

关键词： microplastics microbiota Gut Dysbiosis

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multi-source information fusion:Progress and future

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Chinese Journal of Aeronautics 2024年第7期37卷 24-58页

作者： Xinde LI Fir DUNKIN jean DEZERT School of Automation Southeast UniversityNanjing 210008China Nanjing Center for Applied mathematics Nanjing 211135China Key Laboratory of measurement and Control of CSE Ministry of EducationNanjing 210096China dSoutheast University Shenzhen Research Institute Shenzhen 518063China Information modeling and Processing Department ONERAPalaiseau 92320France

multi-Source Information Fusion(mSIF),as a comprehensive interdisciplinary field based on modern information technology,has gained significant research value and extensive application prospects in various domains,attracting high attention and interest from scholars,engineering experts,and practitioners *** achieving fruitful results in both theoretical and applied aspects over the past five decades,there remains a lack of comprehensive and systematic review articles that provide an overview of recent development in *** light of this,this paper aims to assist researchers and individuals interested in gaining a quick understanding of the relevant theoretical techniques and development trends in mSIF,which conducts a statistical analysis of academic reports and related application achievements in the field of mSIF over the past two decades,and provides a brief overview of the relevant theories,methodologies,and application domains,as well as key issues and challenges currently ***,an analysis and outlook on the future development directions of mSIF are presented.

关键词： multi-sensor system Information fusion Artificial intelligence Pattern recognition Human-machine integration

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Design and Experimental Testing of a moving Coil Actuator with Compensation Coil

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CSEE Journal of Power and Energy Systems 2024年第2期10卷 707-716页

作者： Boyuan Yin Xianwu Zeng John Frederick Eastham Emelie Nilsson jean-francois Rouquette jean Rivenc Ludovic Ybanez Xiaoze Pei Department of Electronics&Electrical Engineering University of BathBathBA27AYUnited Kingdom Airbus UpNext BlangnacFrance Airbus CRT BlangnacFrance Department of mechanical Engineering University of BathBathBA27AYUnited Kingdom

Hydrogen-powered electric aircraft have attracted significant interests aiming to achieve decarbonization *** DC electric networks are facing great challenges in DC fault protection *** interrupters are widely used in low voltage and medium voltage power systems due to being environmentally friendly with low *** this paper a moving coil actuator with compensation coils for a vacuum interrupter,as part of a hybrid direct current circuit breaker,is designed and experimentally *** coils are used to improve operating speed compared with original moving coil *** between four possible connections of compensation coils and original moving coil actuator are carried *** results show comparisons between different connections of actuator coils in terms of opening time and coil current with a range of pre-charged capacitor *** performance of each actuator connection is also *** actuator with compensation coils is shown to have a higher current rising rate and achieve faster opening speed,which is a critical requirement for electric aircraft network *** parallel connection actuator achieves the highest opening speed within 3.5 ms with capacitor voltage of 50 V.

关键词： Circuit breaker compensation coil moving coil actuator vacuum interrupter

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Tanaka Formula and Local Time for a Class of Interacting Branching measure-valued Diffusions

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Acta mathematica Sinica,English Series 2024年第4期40卷 1059-1098页

作者： Donald A.DAWSON jean VAILLANCOURT Hao WANG School of mathematics and Statistics Carleton UniversityOttawaCanada Department of Decision Sciences HECMontrealCanada Department of mathematics University of OregonEugeneUSA

We construct superprocesses with dependent spatial motion(SDSms)in Euclidean spaces R^(d)with d≥1 and show that,even when they start at some unbounded initial positive Radon measure such as Lebesgue measure on R^(d),... 详细信息

关键词： measure-valued diffusions stochastic partial differential equations superprocesses branching processes local time Tanaka formula

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A convolutional neural network to detect possible hidden data in spatial domain images

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Cybersecurity 2024年第1期7卷 37-52页

作者： jean De La Croix Ntivuguruzwa Tohari Ahmad Department of Informatics Institut Teknologi Sepuluh Nopember(ITS)Kampus ITS Keputih SukoliloSurabaya60111Indonesia African Center of Excellence in the Internet of Things College of Science and TechnologyUniversity of Rwanda3900KigaliRwanda

Hiding secret data in digital multimedia has been essential to protect the ***,attackers with a steganalysis technique may break *** steganalysis methods have good results with conventional machine Learning(mL)techniques;however,the introduction of Convolutional Neural Network(CNN),a deep learning paradigm,achieved better performance over the previously proposed mL-based *** the existing CNN-based approaches yield good results,they present performance issues in classification accuracy and stability in the network training *** research proposes a new method with a CNN architecture to improve the hidden data detection accuracy and the training phase stability in spatial domain *** proposed method comprises three phases:pre-processing,feature extraction,and ***,in the pre-processing phase,we use spatial rich model filters to enhance the noise within images altered by data hiding;secondly,in the feature extraction phase,we use two-dimensional depthwise separable convolutions to improve the signal-to-noise and regular convolutions to model local features;and finally,in the classification,we use multi-scale average pooling for local features aggregation and representability enhancement regardless of the input size variation,followed by three fully connected layers to form the final feature maps that we transform into class probabilities using the softmax *** results identify an improvement in the accuracy of the considered recent scheme ranging between 4.6 and 10.2%with reduced training time up to 30.81%.

关键词： Information security Spatial domain steganalysis Deep learning Convolutional neural network Infrastructure

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NRF2 signaling cascade in amyotrophic lateral sclerosis:bridging the gap between promise and reality

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Neural Regeneration Research 2024年第5期19卷 1006-1012页

作者： Pauline Tarot Christelle Lasbleiz jean-Charles Liévens mmDN Univ MontpellierEPHEINSERMMontpellierFrance CNRS ParisFranceEPHEINSERMMontpellierFrance

Amyotrophic lateral sclerosis is a very disabling disease due to the degeneration of motor *** include muscle weakness and atrophy,spasticity,and progressive ***,there is no treatment to reverse damage to motor neurons and cure amyotrophic lateral *** only two treatments actually approved,riluzole and edaravone,have shown mitigated beneficial *** difficulty to find a cure lies in the complexity and multifaceted pattern of amyotrophic lateral sclerosis *** mechanisms,abnormal RNA metabolism,nucleocytoplasmic transport defects,accumulation of unfolded protein,and mitochondrial dysfunction would in fine induce oxidative damage and vice versa.A potent therapeutic strategy will be to find molecules that break this vicious *** the nuclear factor erythroid-2 related factor 2 signaling may fulfill this objective since nuclear factor erythroid-2 related factor 2 has a multitarget profile controlling antioxidant defense,mitochondrial functioning,and *** here discuss the interest of developing nuclear factor erythroid-2 related factor 2-based therapy in regard to the pathophysiological mechanisms and we provide a general overview of the attempted clinical assays in amyotrophic lateral sclerosis.

关键词： amyotrophic lateral sclerosis C9orf72 NRF2 oxidative defense oxidative stress sulforaphane superoxide dismutase 1 TDP43

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