检索结果-南通市图书馆

Origin and diversification of maize: Two teosintes but different contributions

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Molecular Plant 2024年第2期17卷 233-235页

作者： Jonathan Acosta-Bayona Gloria Leon-Martinez jean-philippe Vielle-Calzada Grupo de Desarrollo Reproductivo y Apomixis UGA Laboratorio Nacional de Genomica para la BiodiversidadCinvestav IrapuatoIrapuato Gto CP36825Mexico

The unique topographic,climatic,and latitudinal heterogeneity of Mesoamerica is crucial to understanding the evolutionary emergence of one of the richest cultural and biological regions in the planet and its impact on food *** divided between two regions of large biodiversity-lowland tropical or coastal zones and temperate or subtropical highlands sculpted by parallel sierras and their central plateau-the Mexican territory harbors more than 2000 endemic monocotyledonous species,including several hundred grasses(Poaceae),particularly those belonging to the genus Zea,composed of maize(Zea mays ***)and its wild relatives,collectively referred as teosintes.

关键词： collective planet harbor

Stable femtosecond X-rays with tunable polarization from a laser-driven accelerator

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2017年第1期6卷 410-416页

作者： Andreas Döpp Benoit Mahieu Agustin Lifschitz Cedric Thaury Antoine Doche Emilien Guillaume Gabriele Grittani Olle Lundh Martin Hansson Julien Gautier Michaela Kozlova jean philippe goddet Pascal Rousseau Amar Tafzi Victor Malka Antoine Rousse Sebastien Corde Kim Ta Phuoc Laboratoire d’Optique Appliquée ENSTACNRS UMR7639Ecole PolytechniqueChemin de la Hunière91761 PalaiseauFrance Present address:Ludwig-Maximilians-Universität München Fakultät für PhysikAm Coulombwall 1Garching 85748Germany ELI Beamlines Project Institute of Physics of the ASCRNa Slovance 218221 Prague 8Czech Republic Department of Physics Lund UniversityPO Box 11822100 LundSweden Department of Physics and Complex Systems Weizmann Institute of Science76100 RehovotIsrael

Technology based on high-peak-power lasers has the potential to provide compact and intense radiation sources for a wide range of innovative *** particular,electrons that are accelerated in the wakefield of an intense laser pulse oscillate around the propagation axis and emit *** betatron source,which essentially reproduces the principle of a synchrotron at the millimeter scale,provides bright radiation with femtosecond duration and high spatial ***,despite its unique features,the usability of the betatron source has been constrained by its poor control and *** this article,we demonstrate the reliable production of X-ray beams with tunable *** ionization-induced injection in a gas mixture,the orbits of the relativistic electrons emitting the radiation are reproducible and *** observe that both the signal and beam profile fluctuations are significantly reduced and that the beam pointing varies by less than a tenth of the beam *** polarization ratio reaches 80%,and the polarization axis can easily be *** anticipate a broad impact of the source,as its unprecedented performance opens the way for new applications.

关键词： laser-plasma interaction laser-wakefield acceleration synchrotron light sources

Characteristics of patients with Wilson disease in the United States: An insurance claims database study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第5期16卷 791-799页

作者： Thomas Daniel-Robin Pradeep Kumar Bernard Benichou jean-philippe Combal Vivet Therapeutics Paris 75008France Clarivate Noida 201301Uttar PradeshIndia

BACKGROUND Wilson disease(WD)is a progressive,potentially fatal degenerative disease affecting the liver and central nervous *** its low prevalence,collecting data on large cohorts of patients with WD is *** insur-ance claims databases provide powerful tools to collect retrospective data on large numbers of patients with rare *** To describe patients with WD in the United States,their treatment and clinical outcome,using a large insurance claims *** This retrospective,longitudinal study was performed in the Clarivate Real-World Data Product *** patients with≥2 claims associated with an Interna-tional Classification of Diseases 10(ICD-10)diagnostic code for WD(E83.01)between 2016 and 2021 were included and followed until death or study *** were divided into two groups by whether or not they were documented to have received a specific treatment for *** manifestations,hospital-isations,liver transplantation and death were *** Overall,5376 patients with an ICD-10 diagnostic code for WD were *** mean age at inclusion was 41.2 years and 52.0%were men.A specific WD treatment was documented for 885 patients(15.1%),although the number of patients taking zinc salts may be underestimated due to over the counter *** inclusion,the mean age of patients with a documented treatment was 36.6±17.8 years vs 42.2±19.6 years in those without a documented *** follow-up,273 patients(5.1%)*** with the American general population,the standardised mortality ratio was *** proportion of patients with a documented WD-specific treatment who died during follow-up was 4.0%and the mean age at death 52.7 *** Patients treated for WD in the United States had an excess early mortality compared with the American *** findings indicate that there is a significant unmet need for effective treatment for WD in the United States.

关键词： Wilson disease Mortality Treatment Copper chelators Zinc acetate United States

Rational and Continuous Measurement of Emotional-Fingerprint, Emotional-Quotient and Categorical vs Proportional Recognition of Facial Emotions with M.A.R.I.E., Second Half

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Psychiatry 2024年第4期14卷 400-450页

作者： philippe Granato Shreekumar Vinekar jean-Pierre Van Gansberghe Raymond Bruyer Unit de Rhabilitation Psycho-Sociale Service de Psychiatrie Centre Hospitalier de Denain Denain France Department of Psychiatry and Behavioral Sciences College of Medicine University of Oklahoma Oklahoma City USA Mathematics Consultant Brussels Belgium Institute of Psychological Sciences Center of Neuroscience Cognition and Systems University of Louvain Louvain-la-Neuve Belgium

Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the interfaces of verbal and emotional communications. The progress of AI is significant on the verbal level but modest in terms of the recognition of facial emotions even if this functionality is one of the oldest in humans and is omnipresent in our daily lives. Dysfunction in the ability for facial emotional expressions is present in many brain pathologies encountered by psychiatrists, neurologists, psychotherapists, mental health professionals including social workers. It cannot be objectively verified and measured due to a lack of reliable tools that are valid and consistently sensitive. Indeed, the articles in the scientific literature dealing with Visual-Facial-Emotions-Recognition (ViFaEmRe), suffer from the absence of 1) consensual and rational tools for continuous quantified measurement, 2) operational concepts. We have invented a software that can use computer-morphing attempting to respond to these two obstacles. It is identified as the Method of Analysis and Research of the Integration of Emotions (M.A.R.I.E.). Our primary goal is to use M.A.R.I.E. to understand the physiology of ViFaEmRe in normal healthy subjects by standardizing the measurements. Then, it will allow us to focus on subjects manifesting abnormalities in this ability. Our second goal is to make our contribution to the progress of AI hoping to add the dimension of recognition of facial emotional expressions. Objective: To study: 1) categorical vs dimensional aspects of recognition of ViFaEmRe, 2) universality vs idiosyncrasy, 3) immediate vs ambivalent Emotional-Decision-Making, 4) the Emotional-Fingerprint of a face and 5) creation of population references data. Methods: M.A.R.I.E. enables the rational, quantified measurement of Emotional Visual Acuity (EVA) in an individual obse

关键词： M.A.R.I.E. Universality Idiosyncrasy Measurement of Emotional Quotient Emotional Fingerprint Emotional Decision-Making Limbic Lobe

Rational and Continuous Measurement of the Emotional Decision Making in Visual Recognition of Facial Emotional Expressions with M.A.R.I.E.: First Half

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Psychiatry 2024年第3期14卷 223-264页

作者： philippe Granato Shreekumar Vinekar jean-Pierre Van Gansberghe Raymond Bruyer Unité de R&#233habilitation Psycho-sociale Service de Psychiatrie Centre Hospitalier de Denain Denain France Department of Psychiatry and Behavioral Sciences College of Medicine University of Oklahoma Oklahoma City USA Brussels Belgium Institute of Psychological Sciences Center of Neuroscience Cognition and Systems University of Louvain Louvain la Neuve Belgium

Context: The advent of Artificial Intelligence (AI) requires modeling prior to its implementation in algorithms for most human skills. This observation requires us to have a detailed and precise understanding of the interfaces of verbal and emotional communications. The progress of AI is significant on the verbal level but modest in terms of the recognition of facial emotions even if this functionality is one of the oldest in humans and is omnipresent in our daily lives. Dysfunction in the ability for facial emotional expressions is present in many brain pathologies encountered by psychiatrists, neurologists, psychotherapists, mental health professionals including social workers. It cannot be objectively verified and measured due to a lack of reliable tools that are valid and consistently sensitive. Indeed, the articles in the scientific literature dealing with Visual-Facial-Emotions-Recognition (ViFaEmRe), suffer from the absence of 1) consensual and rational tools for continuous quantified measurement, 2) operational concepts. We have invented a software that can use computer-morphing attempting to respond to these two obstacles. It is identified as the Method of Analysis and Research of the Integration of Emotions (M.A.R.I.E.). Our primary goal is to use M.A.R.I.E. to understand the physiology of ViFaEmRe in normal healthy subjects by standardizing the measurements. Then, it will allow us to focus on subjects manifesting abnormalities in this ability. Our second goal is to make our contribution to the progress of AI hoping to add the dimension of recognition of facial emotional expressions. Objective: To study: 1) categorical vs dimensional aspects of recognition of ViFaEmRe, 2) universality vs idiosyncrasy, 3) immediate vs ambivalent Emotional-Decision-Making, 4) the Emotional-Fingerprint of a face and 5) creation of population references data. Methods: With M.A.R.I.E. enable a rational quantified measurement of Emotional-Visual-Acuity (EVA) of 1) a) an individu

关键词： M.A.R.I.E. Universality Idiosyncrasy Measurement of Emotional Quotient Emotional Fingerprint Emotional Decision-Making Limbic Lobe

An ethically guided preclinical device for phenotyping H_(2)production in laboratory rodents

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Animal Models and Experimental Medicine 2024年第4期7卷 553-561页

作者： Victor Pascal-Moussellard Emilie Boucher Stéphane Tanguy philippe Cinquin Pierre-Alain Barraud ChloéDavin Cordélia Salomez-Ihl Dalil Hannani François Boucher jean-Pierre Alcaraz University Grenoble Alpes CNRSUMR 5525VetAgro SupGrenoble INPTIMCGrenobleFrance

Background:Dihydrogen(H_(2))is produced endogenously by the intestinal microbiota through the fermentation of diet *** the past few years,numer-ous studies have demonstrated the significant therapeutic potential of H_(2)in various pathophysiological contexts,making the characterization of its production in labora-tory species of major preclinical ***:This study proposes an innovative solution to accurately monitor H_(2)pro-duction in free-moving rodents while respecting animal welfare *** devel-oped device consisted of a wire rodent cage placed inside an airtight chamber in which the air quality was maintained,and the H_(2)concentration was continuously *** the airtightness and efficiency of the systems used to control and maintain air quality in the chamber were checked,tests were carried out on rats and mice with different metabolic phenotypes,over 12 min to 1-h experiments and repeatedly.H_(2)production rates(HPR)were obtained using an easy calculation algorithm based on a first-order moving ***:HPR in hyperphagic Zucker rats was found to be twice as high as in control Wistar rats,respectively,2.64 and 1.27 nmol.s^(−1)per *** addition,the ingestion of inulin,a dietary fiber,stimulated H_(2)production in *** were 0.46 nmol.s^(−1)for animals under control diet and 1.99 nmol.s^(−1)for animals under inulin ***:The proposed device coupled with our algorithm enables fine analysis of the metabolic phenotype of laboratory rats or mice with regard to their endogenous H_(2)production.

关键词： hydrogen therapy laboratory rodents microbiota molecular hydrogen noninvasive monitoring device

Vitamin D, Parathyroid Hormone, Insulin Sensitivity and Islet β-Cell Secretory Function in Diabetic Patients from South Kivu in the Democratic Republic of Congo: Cross-Sectional Study

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Diabetes Mellitus 2024年第2期14卷 81-94页

作者： Dieudonne Masemo Bihehe Ahadi Birindwa Bwihangane jean-Paulin Mukonkole Mbo Michel Hermans philippe Bianga Katchunga Faculté de Médecine H&#244pital Général de Référence de Panzi Université Evangélique en Afrique Bukavu DR Congo Département de Biologie Faculté des Sciences Université Officielle de Bukavu Bukavu DR Congo Département de Médecine Interne Université de Kisangani Kisangani DR Congo Service d’endocrinologie et de Diabétologie Cliniques Universitaires Saint-Luc Université Catholique de Louvain Bruxelles Belgique Département de Médecine Interne Cliniques Universitaires de Bukavu Université Officielle de Bukavu Bukavu DR Congo

Background: The role of vitamin D and parathyroid hormone in the metabolic profile of type 2 diabetes mellitus in sub-Saharan Africa has not been adequately assessed. The aim of this study was to determine the prevalence of low vitamin D level and secondary hyperparathyroidism and their association with insulin sensitivity and β-cell secretory function among Congolese type 2 diabetics. Methodology: Fasting glycaemia, fasting insulin, 25OH D3 and human parathyroid hormone (hPTH) were measured in one hundred and eighty-four type 2 diabetic patients followed as outpatients in South Kivu. Levels of 25OH D3 65 pg/ml defined low vitamin D and elevated parathyroid hormone levels, respectively. The HOMA model was used to measure insulin sensitivity and β-cell secretory function. Results: Medians (IQR) were 25.3 (20.4 - 32.4) ng/ml for 25OH D3 and 53.7 (38.4 - 115.7) pg/ml for hPTH. 58.7% of diabetics had insulin resistance, 126 (68.5%) had low vitamin D and 80 (43.5%) had hyperparathyroidism. In multivariate analysis, hPTH (partial r = −0.28;p = 0.0002) and 25OH D3 (partial r = 0.16;p = 0.03) showed an independent association with insulin sensitivity after adjustment for body mass index and waist circumference. Finally, hPTH (partial r = 0.27;p = 0.0002) was the sole determinant of β-cell secretory function. Conclusions: This study confirms the high prevalence of low vitamin D level and secondary hyperparathyroidism and their association with insulin resistance and impaired islet β-cell secretory function among Congolese with type 2 diabetes mellitus. Vitamin D and calcium supplementation should be envisaged for cases of deficiency in this region.

关键词： Vitamin D Parathyroid Hormone Diabetes Mellitus Insulin Resistance South Kivu

Dynamics in the Prevalence of Insulin Resistance between 2005 and 2023 in Type 2 Diabetics in South Kivu in the East of the Democratic Republic of Congo: Cross-Sectional Studies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Diabetes Mellitus 2024年第1期14卷 28-40页

作者： Dieudonné Masemo Bihehe Ahadi Birindwa Bwihangane jean-Paulin Mukonkole Mbo Christian Tshongo Muhindo Michel Hermans philippe Bianga Katchunga Hô pital général de référence de Panzi Faculté de Médecine Université Evangélique en Afrique Bukavu DR Congo Département de Médecine interne Université de Kisangani Provine de la Tshopo DR Congo Département de Médecine interne Université Catholique de Bukavu Bukavu DR Congo Service d’endocrinologie et de diabétologie Cliniques universitaires Saint-Luc Université Catholique de Louvain Bruxelles Belgique Département de Médecine interne Cliniques Universitaires de Bukavu Université Officielle de Bukavu Bukavu DR Congo

Aim: Sub-Saharan Africa is undergoing an epidemiological transition responsible for a change in the metabolic profile in favour of insulin resistance. The aim of this study was to assess the dynamics of the prevalence of insulin resistance and associated risk factors in diabetic patients in the Democratic Republic of Congo between 2005 and 2023. Method: We measured fasting blood glucose and insulin levels and looked for metabolic syndrome parameters (2009 criteria) in type 2 diabetes patients in 2005-2008 (n = 176) and in 2018-2023 (n = 303). The HOMA model was used to measure insulin sensitivity and islet β-cell secretory function. Results: Between 2005 and 2013, the trend was towards an increase in the prevalence of insulin resistance (from 13.1% to 50.8%;p Conclusion: This present study shows an increase in insulin resistance in Congolese urban areas and a persistence of atypical diabetes mellitus in Congolese rural areas, confirming the particularity of the pathophysiology of the disease in African areas currently influenced by the epidemiological transition. Further studies using an appropriate methodology are required.

关键词： Prevalence Diabetes Mellitus Insulin Resistance Metabolic Syndrome South Kivu

Geospatial Analysis of Urban Heat Island Effects and Tree Equity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Forestry 2024年第1期14卷 1-18页

作者： Jillian Gorrell Sharon R. jean-philippe Paul D. Ries Jennifer K. Richards Neelam C. Poudyal Rochelle Butler School of Natural Resources University of Tennessee 203 Third Creek Building Knoxville Tennessee USA

In recent decades, Urban Heat Island Effects have become more pronounced and more widely examined. Despite great technological advances, our current societies still experience great spatial disparity in urban forest access. Urban Heat Island Effects are measurable phenomenon that are being experienced by the world’s most urbanized areas, including increased summer high temperatures and lower evapotranspiration from having impervious surfaces instead of vegetation and trees. Tree canopy cover is our natural mitigation tool that absorbs sunlight for photosynthesis, protects humans from incoming radiation, and releases cooling moisture into the air. Unfortunately, urban areas typically have low levels of vegetation. Vulnerable urban communities are lower-income areas of inner cities with less access to heat protection like air conditioners. This study uses mean evapotranspiration levels to assess the variability of urban heat island effects across the state of Tennessee. Results show that increased developed land surface cover in Tennessee creates measurable changes in atmospheric evapotranspiration. As a result, the mean evapotranspiration levels in areas with less tree vegetation are significantly lower than the surrounding forested areas. Central areas of urban cities in Tennessee had lower mean evapotranspiration recordings than surrounding areas with less development. This work demonstrates the need for increased tree canopy coverage.

关键词： Spatial Analysis Land Cover Urban Heat Island Effect (UHIE) Evapotranspiration Tree Canopy Impervious Surface GIS Prediction Model GIS Machine Learning