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Forensic Medicine and Anatomy Research 2022年第1期10卷 13-26页

作者： Abdoulaye Kanté jean françois uhl Mariam Daou Babou Ba Tata Touré Ousmane Touré Yatera Demba Moumouna Koné Drissa Traoré ouhoum Ongoïba Abdel Karim Koumaré Anatomy Laboratory University of Paris 5 Paris France Anatomy Laboratory University of Sciences Techniques and Technologies of Bamako Bamako Mali URDIA Research Unit Paris Descartes University Paris France Department of Neurology Gabriel Touré University Hospital in Bamako Bamako Mali

Objective: To carry out a 3D vector reconstruction of the muscles of the ventral region of the neck from anatomical sections of the “Korean Visible Human” for educational purposes. Materials and Methods: The anatomical subject was a 33-year-old Korean man who died of leukemia. He was 164 cm tall and weighed 55 kgs. The anatomical sections were made in 2010 after an MRI and a CT scan. A special saw (cryomacrotome) made it possible to make cuts 0.2 mm thick on the frozen body, i.e. 5960 cuts. Sections numbered 1500 to 2000 (or 500 cuts covering the neck) were used for our study. A segmentation by manual contouring of each anatomical element of the anterior neck region was done using Winsurf version 3.5 software on a laptop PC running Windows 7 equipped with an 8 gigabyte RAM.

3D Vector Reconstruction of the Neck Skeleton from the Anatomical Sections of Korean Visible Human at the Anatomical Laboratory of Paris Descartes

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Forensic Medicine and Anatomy Research 2021年第4期9卷 41-53页

作者： Abdoulaye Kanté Mariam Daou jean françois uhl Vincent Delmas Babou Ba Tata Touré Ousmane Touré Moumouna Koné Demba Yatera Youssouf Sidibé Drissa Traoré Bréhima Coulibaly Nouhoum Ongoïba Anatomy Laboratory University of Paris 5 Paris France Anatomy Laboratory University of Sciences Techniques and Technologies of Bamako Bamako Mali Department of Neurology Gabriel Touré University Hospital in Bamako Bamako Mali Faculty of Medicine and Odontostomatology Bamako Mali

Aim: To perform a vector 3D reconstruction of the neck skeleton from the anatomical sections of the “Korean Visible Human” for educational purposes. Material and Methods: The anatomical subject was a 33-year-old Korean male who died of leukemia. It measured 164 cm and weighed 55 kgs. The anatomical cuts were made in 2010 after an MRI and a CT scan. A special saw (cryomacrotome) made it possible to make cuts on the frozen body of 0.2 mm thick or 5960 slices. Sections numbered 1500 to 2000 (500 neck sections) were used for this study. Manual contouring segmentation of each anatomical element of the anterior neck area was done using Winsurf software version 3.5 on a PC. Results: Our vector 3D neck model includes the following: cervical vertebrae, hyoid bone, sternum manubrium and clavicles. This vector model has been integrated into the virtual dissection table Diva3d, a new educational tool used by universities and medical schools to learn anatomy. This model was also put online on the Sketchfab website and printed in 3D using an ENDER 3 printer. Conclusion: This original work is a remarkable educational tool for the study of the skeleton of the neck and can also serve as a 3D atlas for simulation purposes for training therapeutic gestures.

关键词： Neck Skeleton Korean Visible Human 3D Vector Modeling Virtual Dissection Table Diva3d Teaching

Opinions of Students on the Contribution of the DIVA 3D Virtual Dissection Table to the Teaching of Anatomy at the Faculty of Medicine and Odontostomatology of Bamako

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Forensic Medicine and Anatomy Research 2024年第2期12卷 13-25页

作者： Abdoulaye Kanté Tata Touré Ousmane Toumany Chérif Haidara uhl jean françois Mariam Daou Mamadou A. Keita Bakary Keïta Bréhima Bengaly Drissa Traoré Adégné Togo Nouhoum Ongoïba Faculty of Medicine and Odontostomatology of Bamako Bamako Mali University of Paris Descartes Paris France Department of Neurology The Gabriel Tour&#233 University Hospital Bamako Mali Department of General Surgery The Kati Health Center Bamako Mali Anesthesia-Resuscitation Service Commune I Reference Health Center Bamako Bamako Mali Department of General Surgery The Gabriel Tour&#233 University Hospital Bamako Mali

Objective: Study the contribution of the DIVA 3D dissection table in the teaching of anatomy at the Faculty of Medicine and Odontology of Bamako. Material and Methods: This was a qualitative study carried out from November 1 to December 30, 2023 at the clinical and morphological anatomy laboratory of the Faculty of Medicine and Odontostomatology of Bamako. Included in this study were students who participated in practical and tutorial sessions. The variables studied during this study were: the previous performance of dissection on a cadaver by the students, the opinion of the students on dissection on a cadaver, the replacement of dissection on a cadaver by virtual dissection in the absence of a body, the level student satisfaction. Results: We surveyed 130 participants. The average age was 22 ± 0.2 years with extremes of 17 and 29 years. 95.3% of participants were students. According to 66.7% of participants, virtual dissection is a good palliative in the absence of a corpse. 95.3% of participants found using the virtual dissection table easy with an average of 7.88 ± 1.4. The overall assessment was well rated by 99.3% of participants. Conclusion: According to the results of this study, the virtual dissection table should be improved by integrating commented videos. The use of the DIVA 3D virtual dissection table during practical and tutorial sessions is well appreciated by the students. We believe that the teaching of anatomy using 3D digital technology should be included in the study programs of the Faculty of Medicine and Odontostomatology.

关键词： Student Opinion Contribution DIVA 3D Virtual Dissection Table Anatomy Teaching FMOS

3D Vector Reconstruction of the Typical Cervical Vertebra from Anatomical Sections of Korean Visible Human at the Laboratory of Clinical and Digital Anatomy of Paris Descartes University

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Forensic Medicine and Anatomy Research 2020年第3期8卷 55-63页

作者： Abdoulaye Kanté jean franç ois uhl Mariam Daou Vincent Delmas J. S. Park B. S. Chung Babou Ba Nouhoum Ongoï ba Anatomy Laboratory University of Paris 5 Paris France Anatomy Laboratory University of Sciences Techniques and Technologies of Bamako Bamako Mali Department of Neurology Gabriel Touré University Hospital in Bamako Bamako Mali Department of Anatomy Dongguk University School of Medicine Dongguk Republic of Korea

Aim: To carry out a 3D vector reconstruction of the typical cervical vertebra from anatomical sections of the “Korean Visible Human” for educational purposes. Material and Methods: The anatomical subject was a 33-year-old Korean man who died of leukemia. He was 164 cm tall and weighed 55 kg. This man donated his body to science. Her body was frozen and cut into several anatomical sections after an MRI and CT scan. These anatomical sections were made using a special saw called a 0.2 mm thick cryomacrotome. Thus 8100 cuts were obtained. Only the sections numbered 940 to 1200 were used for our study. A segmentation by manual contouring of the different parts of the typical cervical vertebra was made using the software Winsurf version 3.5 on a laptop PC running Windows 7 equipped with a Ram of 8 gigas. Results: Our 3D vector model of the typical cervical vertebra is easily manipulated using the Acrobat 3DPDF interface. Each part of the vertebra accessible in a menu can be displayed, hidden or made transparent, and 3D labels are available as well as educational menus for learning anatomy. Conclusion: This original work constitutes a remarkable educational tool for the anatomical study of the typical cervical vertebra and can also be used as a 3D atlas for simulation purposes for training in therapeutic gestures.

关键词： Three-Dimensional Anatomy Korean Human Visible Modeling of the Typical Cervical Vertebra Virtual Reality 3D Reconstruction Virtual Dissection Surgical Simulation Surgical Training

Analysis of single nucleotide polymorphisms in the region of CLDN2-MORC4 in relation to inflammatory bowel disease

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World Journal of Gastroenterology 2013年第30期19卷 4935-4943页

作者： Jan Sderman Elisabeth Norén Malin Christiansson Hanna Bragde Raphaele Thiébaut jean-Pierre Hugot Curt Tysk Colm A O'Morain Miquel Gassull Yigael Finkel jean-Frédéric Colombel Marc Lémann Sven Almer Division of Medical Diagnostics Ryhov County Hospital55185 JnkpingSweden Department of Clinical and Experimental Medicine Linkping University58183 LinkpingSweden INSERM U843Université Paris DiderotHpital Robert Debré75019 ParisFrance Université ParisDiderot Sorbonne Paris-Cité UMR84375018 ParisFrance Assistance Publique-Hopitaux de Paris Hopital Robert Debré75019 ParisFrance Division of Gastroenterology Department of MedicineUniversity HospitalSchool of Health and Medical Sciencesrebro University70185 rebroSweden School of Health and Medical Sciences rebro University70185 rebroSweden Department of Gastroenterology Adelaide and Meath HospitalTallaghtDublin 24Ireland Trinity College Dublin College GreenDublin 2Ireland Health Sciences Research Institute Germans Trias i Pujol08916 BadalonaSpain Department of Gastroenterology Sachs' Children's HospitalSdersjukhuset11861 StockholmSweden EPIMAD group Registre EPIMADService d'Epidémiologie et de Santé PubliqueHpital CalmetteCentre Hospitalier Universitaire de Lille59037 LilleFrance Icahn School of Medicine at Mount Sinai New YorkNY 10029United States GETAID group Groupe d'Etude Thérapeutiques des Affections Inflammatoires DigestivesService de gastroentérologieHpital Saint Louis75010 ParisFrance Department of Gastroenterology uhl County Council of stergtland58185 Link pingSweden Division of Gastroenterology Karolinska InstitutetDepartment of Gastroenterology and HepatologyKarolinska university hospital14186 StockholmSweden

AIM:To investigate a possible genetic influence of claudin(CLDN)1,CLDN2 and CLDN4 in the etiology of inflammatory bowel ***:Allelic association between genetic regions of CLDN1,CLDN2 or CLDN4 and patients with inflammatory bowel disease,Crohn's disease(CD)or ulcerative colitis were investigated using both a casecontrol study approach(one case randomly selected from each of 191 Swedish inflammatory bowel disease families and 333 controls)and a family-based study(463 non-Swedish European inflammatory bowel disease-families).A nonsynonymous coding single nucleotide polymorphism in MORC4,located on the same linkage block as CLDN2,was investigated for association,as were two novel CLDN2 single nucleotide polymorphism markers,identified by ***:A single nucleotide polymorphism marker(rs12014762)located in the genetic region of CLDN2 was significantly associated to CD(case-control allelic OR = 1.98,95%CI:1.17-3.35,P = 0.007).MORC4 was present on the same linkage block as this CD *** the case-control approach,a significant association(case control allelic OR = 1.61,95%CI:1.08-2.41,P = 0.018)was found between CD and a nonsynonymous coding single nucleotide polymorphism(rs6622126)in *** association between the CLDN2 marker and CD was not replicated in the familybased *** colitis was not associated to any of the single nucleotide polymorphism ***:These findings suggest that a variant of the CLDN2-MORC4 region predisposes to CD in a Swedish population.

关键词： Crohn’s disease Genetic predisposition Inflammatory bowel disease Single nucleotide polymorphism Tight junctions