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Results of the First 10 Cases of Coronary Bypass Surgery in Senegal

World Journal of Cardiovascular Surgery 2024年第4期14卷 45-60页

作者： Papa Amath Diagne jean claude Ndiogou Dione Papa Ousmane Ba Momar Sokhna Diop El Hadji Boubacar Ba Momar Dioum Marième Soda Mbaye Moussa Seck Diop Mory Camara Abdou Lahad Mbengue Abdou Aziz Thiaw Abdoul Khoudoss Diallo Moussa Mareme Samba Dialtabé Ibrahima Guéssé Ba Anta Mbaye Sall Papa Salmaneba Amadou Gabriel Ciss Department of Cardiovascular and Thoracic Surgery FANN National University Hospital Dakar Senegal

This is a review of the first 10 coronary artery bypass surgeries performed by the local team. The mean age was 62 years old [45 - 74]. The patients were predominantly male, with a M/F ratio of 4:1. Cardiovascular risk factors were mainly myocardial infarction (MI) (60%), hypertension (50%), obesity (40%) and diabetes (30%), with at least two risk factors per patient. Angina was the main symptom (80%). The average time from presentation to surgery was 8 months. The mean Euroscore 2 was 2.92 ± 1.65 [1.33 - 6.60]. Coronary angiography revealed an average of 2 lesions per patient, with 3-vessel involvement in 70% of cases: the Interventricular artery (IVA) (100%), the right coronary artery (90%) and the circumflex artery (70%). On echocardiography, the mean Left ventricular ejection fraction (LVEF) was 59% [33% - 76%]. All patients underwent median sternotomy with bypass grafting. The average duration of the cardiopulmonary bypass was 150 min [46 - 275 min];that of aortic clamping, 120 min [43 - 232 min]. The grafts used were internal thoracic artery (ITA) in 100% of cases (80% on the left and 20% on the right), and the great saphenous vein (GSV) in 60% of cases (50% on the left and 10 on the right). Double bypass was performed in 60% of cases, single bypass in 30% and triple bypass in 10%. The bypasses were performed on the IVA (100%), the middle lateral of the circumflex (30%) and the bisector (20%). The average time to extubation was 11 hours and the length of stay in the intensive care unit was 7 days [03 - 17 days]. One patient had a reoperation on Day 0 post-op. The average hospital stay was 13 days [06 - 27 days]. Complications occurred in nine of the patients (90%), with a predominance of infectious and neurological complications. Overall operative mortality was 3%, all in intensive care.

关键词： Coronary Bypass Surgery Coronary Lesions Cardiac Surgery Senegal

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Integrating Functional Status Information into Knowledge Graphs to Support Self-Health Management

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Data Intelligence 2023年第3期5卷 636-662页

作者： Mauro Dragoni Tania Bailoni Ivan Donadello jean-claude Martin Helena Lindgren Fondazione Bruno Kessler TrentoItaly Free University of Bolzano BolzanoItaly LISN-CNRS Universite Paris SaclayParisFrance Umea University UmeaSweden

Functional Status Information(FSI)describes physical and mental wellness at the whole-person *** includes information on activity performance,social role participation,and environmental and personal factors that affect the well-being and quality of *** and analyzing this information is critical to address the needs for caring for an aging global population,and to provide effective care for individuals with chronic conditions,multi-morbidity,and *** knowledge graphs(PKGs)represent a suitable way for meaning in a complete and structured way all information related to people's FSI and reasoning over them to build tailored coaching solutions supporting them in daily life for conducting a healthy *** this paper,we present the development process related to the creation of a PKG by starting from the HeLis ontology in order to enable the design of an Al-enabled system with the aim of increasing,within people,the self-awareness of their own functional *** particular,we focus on the three modules extending the HeLis ontology aiming to represent(i)enablers and(ii)barriers playing potential roles in improving(or deteriorating)own functional status and(iii)arguments driving the FSI collection ***,we show how these modules have been instantiated into real-world scenarios.

关键词： Knowledge Graph Personal Healthcare Functional Status Enablers Barriers Arguments

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Origami-Based Design for 4D Printing of 3D Support-Free Hollow Structures

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Engineering 2022年第5期8卷 70-82页

作者： Bingcong Jian Frederic Demoly Yicha Zhang H.Jerry Qi jean-claude Andre Samuel Gomes Laboratoire Interdisciplinaire Carnot de Bourgogne UMR 6303 Centre National de la Recherche Scientifique&Universitede Technologie de Belfort-MontbeliardUniversite Bourgogne Franche-ComteBelfort 90400France George W.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Laboratoire Reactions et Genie des Procedes UMR 7274 Centre National de la Recherche Scientifique-Universitede LorraineNancy 54001France

The integration of additive manufacturing(AM)in design and engineering has prompted a wide spectrum of research efforts,involving topologically optimized solid/lattice structures,multimaterial structures,bioinspired organic structures,and multiscale structures,to name a ***,except for obvious cases,very little attention has been given to the design and printing of more complex three-dimensional(3D)hollow structures or folded/creased *** of the main reasons is that such complex open or closed 3D cavities and regular/freeform folds generally lead to printing difficulties from support-structure-related *** address this barrier,this paper aims to investigate four-dimensional(4D)printing as well as origami-based design as an original research direction to design and build 3D support-free hollow *** work consists of describing the rough 3D hollow structures in terms of two-dimensional(2D)printed origami precursor layouts without any support *** origami-based definitions are then embodied with folding functions that can be actuated and fulfilled by 3D printed smart *** desired 3D shape is then built once an external stimulus is applied to the active materials,therefore ensuring the transformation of the 2D origami layout to 3D *** demonstrate the relevance of the proposal,some illustrative cases are introduced.

关键词： Origami-based design 4D printing Smart material Hollow 3D structures Additive manufacturing

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Urbanization reduces resource use efficiency of phytoplankton community by altering the environment and decreasing biodiversity

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Journal of Environmental Sciences 2022年第2期34卷 140-151页

作者： Yigang Yang Huihuang Chen Mamun Abdullah Al jean claude Ndayishimiye Jun R Yang Alain Isabwe Anqi Luo Jun Yang Aquatic EcoHealth Group Fujian Key Laboratory of Watershed EcologyKey Laboratory of Urban Environment and HealthInstitute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China University of Chinese Academy of Sciences Beijing 100049China Engineering Research Center of Ecology and Agricultural Use of Wetland(Ministry of Education) College of AgricultureYangtze UniversityJingzhou 434025China

Urbanization often exerts multiple effects on aquatic and terrestrial organisms,including changes in biodiversity,species composition and ecosystem ***,the impacts of urbanization on river phytoplankton in subtropical urbanizing watersheds remain largely ***,we explored the effects of urbanization on phytoplankton community structure(i.e.,biomass,community composition and diversity)and function(i.e.,resource use efficiency)in a subtropical river at watershed scale in southeast China over 6 years.A total of 318 phytoplankton species belonging into 120 genera and 7 phyla were identified from 108 *** biomass showed an increasing trend with increasing urbanization *** phytoplankton community shifted from Chlorophyta dominance in rural upstream waters to Bacillariophyta dominance in urbanized downstream ***,phytoplankton diversity and resource use efficiency(RUE=phytoplankton biomass/total phosphorus)were significantly decreased with increasing urbanization level from upstream to *** RUE exhibited a significant positive correlation with species richness,but a negative correlation with phytoplankton *** variation in environmental factors(turbidity,total nitrogen,NH_(4)^(+)-N,total phosphorus,PO_(4)^(3-)-P and percentage urbanized area)was significantly correlated with phytoplankton diversity and ***,our results revealed the influence of urbanization on phytoplankton community structure and ecosystem function was due to its altering the environmental ***,human-driven urbanization may play crucial roles in shaping the structure and function of phytoplankton communities in subtropical rivers,and the mechanism of this process can provide important information for freshwater sustainable uses,watershed management and conservation.

关键词： Plankton Community functioning Subtropical river Urbanization gradient Land use Watershed ecology

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Lanthanide-doped nanoscintillators

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Light(Science & Applications) 2022年第10期11卷 2264-2266页

作者： jean-claude Georges Bünzli institute of Chemical Sciences and Engineering Swiss Federal Institute of TechnologyLausanne(EPFL)LausanneSwitzerland Department of Biomedical Engineering Southern University of Science and Technology(SUSTech)ShenzhenChina

Lanthanide-doped nanoscintillators are taking the lead in several important fields including radiation detection,biomedicine,both at the level of diagnosis and therapy,and information encoding.

关键词： diagnosis Lanthanide ill

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Computational design for 4D printing of topology optimized multi-material active composites

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npj Computational Materials 2023年第1期9卷 2342-2350页

作者： Darshan Athinarayanarao Romaric Prod’hon Dominique Chamoret H.Jerry Qi Mahdi Bodaghi jean-claude André Frédéric Demoly ICB UMR 6303 CNRS Univ.Bourgogne Franche-ComtéUTBM90010 BelfortFrance The George W.Woodruff School of Mechanical Engineering Georgia Institute of TechnologyAtlantaGA 30332USA Department of Engineering School of Science and TechnologyNottingham Trent UniversityNottingham NG118NSUK LRGP UMR 7274 CNRS University of LorraineNancyFrance

Recent efforts on design for four-dimensional(4D)printing have considered the spatial arrangement of smart materials and energy *** development of multifunctional structures and their desired mechanical/actuation performances require tackling 4D printing from a multi-material design *** the materials distributions there is an opportunity to increase the spectrum of design concepts with computational *** main goal being to achieve the“best”distribution of material properties in a voxelized structure,a computational framework that consists of a finite element analysis-based evolutionary algorithm is *** fuses the advantages of optimizing both the materials distribution and material layout within a design space via topology optimization to solve the inverse design problem of finding an optimal design to achieve a target shape change by integrating void *** results demonstrate the efficacy of the proposed method in providing a highly capable tool for the design of 4D-printed active composites.

关键词： composites printing topology

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Gn filling orbicular N-sided holes using periodic B-spline surfaces

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Science China(Information Sciences) 2011年第7期54卷 1383-1394页

作者： PAUL jean-claude Tsinghua National Laboratory for Information Science and Technology Institute National de Recherche en Informatique et en Automatique School of Software Tsinghua University Key Laboratory for Information System Security Ministry of Education of China

The orbicular N -sided hole filling problem is usually introduced by filleting an end-point of a part with large *** existing methods based on quadrilateral partition or constrained-optimization can rarely generate high-order continuous blending surfaces under these *** paper first reparameterizes the boundary of the specified orbicular N -sided hole to ensure the compatibility of neighboring cross-boundary derivatives on the connecting points,preserving their G n *** we compute the control points of the periodic B-spline surface using the sufficient G n continuity condition on the pole and the algorithm of extending parametric *** method generates single blending surface,which can be converted into standard Bspline surface by adding knots without introducing *** only elevates the degree of the boundary by *** construction method is simple and efficient,without iteration nor large-scale matrix *** achieves G n continuity under compatible *** blending examples underline its feasibility and practicability.

关键词： CAD periodic B-spline surface polar coordinates N -sided hole filling G n continuity

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Regulation of Sulfate Uptake and Assimilation——the Same or Not the Same？

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Molecular Plant 2010年第2期3卷 314-325页

作者： jean-claude Davidian Stanislav Kopriva Unite mixte de recherche Biochimie et Physiologie Molculaire des Plantes Montpellier SupAgro/CNRS/INRA/UM2 2 place Pierre Viala 34060 MontpellierCedex 2 France Department of Metabolic Biology John Innes Centre Norwich NR4 7UH UK

Plant take up the essential nutrient sulfur as sulfate from the soil, reduce it, and assimilate into bioorganic compounds, with cysteine being the first product. Both sulfate uptake and assimilation are highly regulated by the demand for the reduced sulfur, by availability of nutrients, and by environmental conditions. In the last decade, great prog- ress has been achieved in dissecting the regulation of sulfur metabolism. Sulfate uptake and reduction of activated sulfate, adenosine 5＇-phosphosulfate （APS）, to sulfite by APS reductase appear to be the key regulatory steps. Here, we review the current knowledge on regulation of these processes, with special attention given to similarities and differences.

关键词： Metabolic regulation nutrient and metal transport nutrition primary metabolism sulfate uptake sulfur metabolism.

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The contribution of solid-state chemistry in the determination of multicomponent phase diagrams

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Rare Metals 2006年第5期25卷 576-581页

作者： jean claude Tedenac Franck Gascoin Didier Ravot Université Montpellier 2 LPMC-UMR-CNRS-5617 MontpellierFrance

For a long period of time, the determination of phase diagrams was only supported by experiments related to thermal effects or thermodynamic measurements： thermal analysis, calorimetric measurements, vapor pressures, and EMF measurements. As a matter of fact, solid-solid transformations were not so accurately determined and could not be taken into account in the system＇s analysis. First, X-ray diffraction methods were used as a support for the thermal analysis. Second, the implementation of novel tools in structural analysis （for example, the Rietveld method） has permitted to increase the knowledge of phase stability. Finally, modeling the phases using a Calphad method needed increasingly more structural results to determine and better understand the phase diagrams. On the other hand, the Calphad method has been widely developed for metallic systems, for oxide systems, and in the past 10 years, for some semi-conductor systems, for example, gallium arsenide, cadmium telluride, and lead telluride systems. In such applications, it is very important to bring point defects in the modeling of the phases to map the defects as a function of the chemical composition. Owing to its complexity, this characteristic, the knowledge of which is crucial for the understanding and the control of potential physical applications, was ignored in the previous assessment of semi-conductor systems.

关键词： thermodynamic modeling solid-state chemistry phase diagram

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ON MAXWELL EQUATIONS WITH THE TRANSPARENT BOUNDARY CONDITION

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Journal of Computational Mathematics 2008年第3期26卷 284-296页

作者： Zhiming Chen jean-claude Nédélec LSEC ICMSEC Academy of Mathematics and Systems Science Chinese Academy of Sciences Beijing 100080 China Centre de Mathématiques Appliquées Ecole Polytechnique 91228 Palaiseau Cedex France

In this paper we show the well-posedness and stability of the Maxwell scattering problem with the transparent boundary condition. The proof depends on the well-posedness of the time-harmonic Maxwell scattering problem... 详细信息

关键词： Electromagnetic scattering Well-posedness Stability

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