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Surgical Management of Lumbar Spinal Canal Stenosis with Instrumentation at the Yaounde Central Hospital: Comparison of Unilateral versus Bilateral Pedicle Screw Fixation Combined with Transforaminal Lumbar Interbody Fusion

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Open Journal of Modern Neurosurgery 2024年第3期14卷 179-189页

作者： Orlane Toto Ndome Nassourou Oumarou Haman Dimitri Fogue jean bruno ndoumou Ronaldo Fonju Anu Indira Baboke Vincent De Paul Djientcheu Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Department of Neurosurgery Douala General Hospital Douala Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde Cameroon Department of Neurosurgery Yaounde General and Central Hospitals Yaounde Cameroon Cameroon Academy of Young Scientists Yaounde Cameroon

Introduction: The choice of adopting unilateral pedicle screw fixation or using bilateral pedicle screw fixation in lumbar spinal stenosis remains controversial. In our context, very few studies have been performed comparing the clinical effectiveness of unilateral versus bilateral fixation in the surgical management of lumbar spinal canal stenosis. Objective: Evaluate the impact on quality of life and clinical efficacy of unilateral spondylodesis compared to bilateral spondylodesis in the surgical management of lumbar spinal canal stenosis at the Yaounde Central Hospital. Methods: This was a retrospective descriptive cross-sectional study for a period of 4 years, from June 2015 to June 2019. It involved all patients operated for lumbar canal stenosis and who underwent spondylodesis or spinal fusion at the neurosurgery department of the Yaounde Central Hospital. Results: A total of 68 participants were recruited during our study period. 32 (47%) of the study population were in the 50 - 60 age group, with a mean age of 56.98 years ranging from 41 to 75 years. Females, housewives and farmers were the most affected. In our study, 72% of patients had unilateral spondylodesis and 28% had bilateral fusion. Preoperatively, 71% of patients had insurmountable pain, refractory to medical treatment. At 3 months postoperatively, 73.7% of patients with bilateral setup had moderate pain compared to 69% of those with unilateral setup. At 6 months postoperatively, 79% of patients with bilateral fusion had mild pain compared to 82% of patients with unilateral setup. At 1 year postoperatively, all patients had mild pain. Preoperatively, 66.2% of patients were unable to walk and 19.1% of patients were bedridden according to the Oswestry score. At 3 months postoperatively, 10.2% of patients with unilateral setup were unable to walk compared to 10.5% of patients with bilateral fixation, while 67.3% of patients with unilateral fixation had moderate disability compared to 52.6% of patient

关键词： Lumbar Spinal Canal Stenosis Instrumentation Surgery Quality of Life

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Monitoring and factors affecting levels of airborne and water bromoform in chlorinated seawater swimming pools

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Journal of Environmental Sciences 2017年第8期29卷 262-270页

作者： jean-Luc Boudenne Julien Parinet Carine Demelas Tarek Manasfi bruno Coulomb Aix Marseille Univ CNRS LCE13331 Marseille France Arises 94700 Maisons-Alfort France

Water and air quality of eight seawater swimming pools using chlorine disinfection was measured during four sampling campaigns, spread on one full-year, and in four thalassotherapy centers located in Southeast of France. Concentrations of trihalomethanes（THMs） in air and in water as well as concentrations of parameters, including nonpurgeable organic carbon（NPOC）, free residual chlorine（Cl_f）, pH, Kjeldhal Nitrogen（KN）, salinity,conductivity, bromide ions and, water and air temperature, were measured. Water and air samples were collected in triplicates morning — at the opening of the pools —, noon and night — at the closing of the pools —, in summer and winter. Data analysis was performed by Principal Component Analysis（PCA） and rotated component matrix, from both data quality and other parameters such as TOC, aromaticity（UV_（254））, pH, hygrometry, and free residual chlorine（Cl_f）. This statistical analysis demonstrates a high correlation between TOC, Cl_fand UV_（254） and THM levels found in air and water, particularly for the major ones（CHBr_3in water：300.0 μg/L mean, 1029.0 μg/L maximum; CHBr_3 in air： 266.1 μg/m^3 mean,1600.0 μg/m^3 maximum, and CHClBr_2 in water： 18.9 μg/L mean, 81.0 μg/L maximum;CHClBr_2 in air： 13.6 μg/m^3 mean, 150.0 μg/m^3maximum）. These high levels of bromoform（CHBr_3） are particularly worrisome in such health institutions, even these levels do not exceed the Permissible Exposure Limit（PEL） of 5 mg/m^3 as an 8 hour time-weighted average currently fixed by various administrations, such as Occupational Safety and Health Administration（OSHA）.

关键词： Trihalomethanes Bromoform Air Seawater Swimming pool Brominated compounds

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A SEM-based method to determine the mineralogical composition and the particle size distribution of suspended sediment

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International Journal of Sediment Research 2019年第2期34卷 85-94页

作者： Sylvain Pinet bruno Lartiges jean-Michel Martinez Sylvain Ouillonc University of Toulouse (Paul Sabatier) Geosciences Environment ToulouseCNRS(Centre National de la Recherche Scientifique)IRD(Institut de Recherche pour le Développement) Instituto de Geosciencias Universidade de BrasiliaCampus Universitario Darcy RibeiroICC Centro University of Toulouse LEGOS(Laboratoire d'Etudes en Géophysique et Océanographie Spatiales)

A robust method for characterizing the mineralogy of suspended sediment in continental rivers is *** encompasses 3 steps:the filtration of a few milliliters of water,measurements of X-ray energy dispersive spectra using Scanning Electron Microscopy(SEM),and robust machine learning tools of *** method is applied to suspended particles collected from various Amazonian rivers.A total of more than 204,000 particles were analyzed by SEM-EDXS(Energy Dispersive X-ray Spectroscopy),*** 15,700 particles per sampling station,which lead to the identification of 15 distinct groups of mineralogical *** size distribution of particles collected on the filters was derived from the SEM micrographs taken in the backscattered electron imaging mode and analyzed with ImageJ *** determination of the main mineralogical groups composing the bulk sediment associated with physical parameters such as particle size distribution or aspect ratio allows a precise characterization of the load of the terrigenous particles in rivers or *** the case of the Amazonian rivers investigated,the results show that the identified mineralogies are consistent with previous studies as well as between the different samples *** method enabled the evolution of grain size distribution from fine to coarse material to be described in the water *** about hydrodynamic sorting of mineral particles in the water column are also briefly *** proposed method appears well suited for intensive routine monitoring of suspended sediment in river systems.

关键词： Mineralogy Scanning Electron Microscopy Suspended sediment Machine learning Particle size distribution

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Impact of homogeneous pathologic response to preoperative chemotherapy in patients with multiple colorectal liver metastases

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World Journal of Gastroenterology 2017年第45期23卷 8027-8034页

作者： Charles Sabbagh Denis Chatelain Christophe Attencourt jean-Paul Joly bruno Chauffert Cyril Cosse jean-Marc Regimbeau Depart-ment of Digestive and Oncologic Surgery Amiens University Medical Center INSERM U1088 Jules Verne University of Picardie University of Picardie Department of Anatomic Pathology Amiens University Medical Center Department of Hepatogastroenterology Amiens University Medical Center Department of Medical Oncology Amiens University Medical Center EA4294 Jules Verne University of Picardie

AIM To analyze the homogeneity of pathologic response to preoperative chemotherapy(PRPC) after chemotherapy in patients with multiple liver metastases(LM).METHODS From September 2011 to August 2014,patients with at least two LM undergoing preoperative chemotherapy prior to resection were included in this retrospective,single-center study. The endpoints were PRPC homogeneity(according to both the Rubbia-Brandt and MD Anderson classifications),the impact of PRPC on the MDT decision,factors associated with homogeneous PRPC and overall survival of patients with vs. without homogeneous *** seventy-three patients with a total of 88 liver resections(including 15 two-stage procedures) were included in the study. The homogeneous PRPC rate was 55% according to the Rubbia-Brandt classification and 53% according to the MD Anderson classification. The MDT decision was modified by the PRPC in only 2.7% of patients(n = 2). CONCLUSION The PRPC was homogeneous in only one half of patients and had very little influence on the MDT decision.

关键词： Liver metastases Pathological response Homogeneity Preoperative chemotherapy Colorectal cancer

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Relative importance of long-term changes in climate and land-use on the phenology and abundance of legume crop specialist and generalist aphids

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Insect Science 2019年第5期26卷 881-896页

作者： Martin Luquet Maurice Hulle jean-Christophe Simon Nicolas Parisey Christelle Buchard2 bruno Jaloux Agrocampus Ouest Centre of AngersInstitute of GeneticsEnvironment and Plant Protection (IGEPP-Joint Research Unit 1349) AngersFrance INRA Institute of GeneticsEnvironment and Plant Protection (IGEPP-Joint Research Unit 1349)Le Rheu France

Abstract Insect populations are prone to respond to global changes through shifts in phenology, distribution and abundance. However, global changes cover several factors such as climate and land-use, the relative importance of these being largely unknown. Here, we aim at disentangling the effects of climate, land-use, and geographical drivers on aphid abundance and phenology in France, at a regional scale and over the last 40 years. We used aerial data obtained from suction traps between 1978 and 2015 on five aphid species varying in their degree of specialization to legumes, along with climate, legume crop area and geographical data. Effects of environmental and geographical variables on aphid annual abundance and spring migration dates were analyzed using generalized linear mixed models. We found that within the last four decades, aphids have advanced their spring migration by a month, mostly due to the increase in temperature early in the year, and their abundance decreased by half on average, presumably in response to a combination of factors. The influence of legume crop area decreased with the degree of specialization of the aphid species to such crops. The effect of geographical variation was high even when controlling for environmental variables, suggesting that many other spatially structured processes act on aphid population characteristics. Multifactorial analyses helped to partition the effects of different global change drivers. Climate and land-use changes have strong effects on aphid populations, with important implications for future agriculture. Additionally, trait-based response variation could have major consequences at the community scale.

关键词： abundance climate warming degree of specialization land-use change legume aphids phenology

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The contribution of microorganisms and metazoans to mineral nutrition in bromeliads

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Journal of Plant Ecology 2016年第3期9卷 241-255页

作者： Céline Leroy jean-François Carrias Régis Céréghino bruno Corbara IRD UMR AMAP(botAnique et Modélisation de l’Architecture des Plantes et des végétations)Boulevard de la LirondeTA A‐51/PS2F‐34398 Montpellier Cedex 5France UMR Ecologie des Forêts de Guyane(AgroParisTech CIRADCNRSINRAUniversitéde GuyaneUniversitédes Antilles)Campus AgronomiqueBP 316F-97379 Kourou cedexFrance UniversitéClermont Auvergne UniversitéBlaise PascalBP 10448F-63000 Clermont-FerrandFrance CNRS UMR 6023Laboratoire Microorganismes:Génome et EnvironnementCampus Universitaire des Cézeaux1 impasse Amélie MuratTSA 60026 CS *** Aubière cedexFrance Universitéde Toulouse INPUPS EcoLab(Laboratoire Ecologie Fonctionnelle et Environnement)F-31062 ToulouseFrance CNRS EcoLab118 Route de NarbonneF-31062 ToulouseFrance

Aims One critical challenge for plants is to maintain an adequate nutrient supply under fluctuating environmental *** is particularly true for epiphytic species that have limited or no access to the pedosphere and often live in harsh *** have evolved key innovations such as epiphytism,water-absorbing leaf trichomes,tank habit and Crassulacean acid metabolism(CAM)photosynthesis that enable them to survive under various environmental *** encompass diverse ecological types that live on different substrates(they can be terrestrial,epilithic or epiphytic)and vary in their ability to retain water(they can be tank-forming or tankless)and photosynthetic pathway(i.e.C3 or CAM).In this review,we outline the nutritional modes and specializations that enable bromeliads to thrive in a wide range of nutrient-poor(mostly nitrogen-depleted)*** FindingsBromeliads have evolved a great diversity of morphologies and functional adaptations leading to the existence of numerous nutritional *** on species that have absorptive foliar trichomes,we review evidence that bromeliads have evolved multi-faceted nutritional strategies to respond to fluctuations in the supply of natural nitrogen(N).These plants have developed mutualistic associations with many different and functionally diverse terrestrial and aquatic microorganisms and metazoans that contribute substantially to their mineral nutrition and,thus,their fitness and *** and fungal microbiota-assisted N provisioning,protocarnivory,digestive mutualisms and myrmecotrophic pathways are the main strategies used by bromeliads to acquire *** combination of different nutritional pathways in bromeliads represents an important adaptation enabling them to exploit nutrient-poor ***,as has been shown for several other vascular plants,multiple partners are involved in nutrient acquisition indicating that there have been convergent adap

关键词： digestive mutualism insect-assisted nutrients leafδ15N multiple N sources myrmecotrophy

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Foundations and implications of Human Aging Omics:A framework for identifying cumulative health risks from embryo to senescence

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Science Bulletin 2024年第20期69卷 3184-3187页

作者： Xiaoying Zheng Binbin Su Yihao Zhao Chen Chen bruno Vellas jean-Pierre Michel Ruitai Shao School of Population Medicine and Public Health Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China APEC Health Science Academy(HeSAY) Peking UniversityBeijing 100871China Department of Geriatric Health Sciences School of Population Medicine and Public HealthChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China Gérontopôle&Department of Geriatric Internal Medicine Toulouse University HospitalToulouse 31000France Geneva University Medical School Geneva 1205Switzerland

We are witnessing a global demographic shift towards an aging society,driven by significant improvements in life *** the past two decades,the average life expectancy has increased by more than 6 years from 66.8 years ... 详细信息

关键词： life aging identifying

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An update to monocanalicular stent surgery

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International Journal of Ophthalmology(English edition) 2016年第5期9卷 797-798页

作者： bruno Eric Fayet William R Katowitz Emmanuel Racy jean-Marc Ruban James A Katowitz Hotel de Ophthalmology Place Du Parvis Natre DameParis 75004France Department of Ophthalmology 34th and Civic Center Boulevard the Children's Hospital of PhiladelphiaPennsylvania 19104USA Clinique Saint-jean-de-Dieu-ENT 19 Rue OudinotParis 75007France Edouard Herriot Hospital Place D'arsonval Lyon 69003France

Dear Sir,I n their article, ＂A comparison between monocanalicular and pushed monocanalicular silicone intubation in the treatment of congenital nasolacrimal duct obstruction＂, Andalib et al present the results of a prospective study on congenital nasolacrimal duct obstruction treated either with a Monoka stent （using a Crawford hook for nasal retrieval） or a Masterka pushed technique for insertion of the Masterka stent. The success rates were respectively 90% and 50%.

关键词： An update to monocanalicular stent surgery

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Movement behaviors and their association with depressive symptoms in Brazilian adolescents:A cross-sectional study

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Journal of Sport and Health Science 2022年第2期11卷 252-259页

作者： bruno Goncalves Galdino da Costa jean-Philippe Chaput Marcus Vinicius Veber Lopes Luis Eduardo Argenta Malheiros Kelly Samara Silva Research Centre in Physical Activity and Health Federal University of Santa CatarinaFlorianopolis88040-900Brazil Healthy Active Living and Obesity Research Group Children’s Hospital of Eastern Ontario Research InstituteOttawaON K1H 8L1Canada

Background:Physical activity,sleep,and sedentary behaviors compose 24-h movement behaviors and have been independently associated with depressive ***,it is not clear whether it is the movement behavior itself or other contextual factors that are related to depressive *** objective of the present study was to examine the associations between self-reported and accelerometer-measured movement behaviors and depressive symptoms in ***:Cross-sectional data from 610 adolescents(14-18 years old)were *** answered questions from the Center for Epidemiological Studies Depression scale and reported time spent watching videos,playing videogames,using social media,time spent in various physical activities,and daytime ***-worn accelerometers were used to measure sleep duration,sleep efficiency,sedentary time,and physical ***-effects logistic regressions were ***:Almost half of the adolescents(48%)were classified as being at high risk for depression(score≥20).No significant associations were found between depressive symptoms and accelerometer-measured movement behaviors,self-reported non-sport physical activity,watching videos,and playing ***,higher levels of self-reported total physical activity(odd ratio(OR)=0.92,95%confidence interval(95%CI):0.86-0.98)and volume of sports(OR=0.88,95%CI:0.79-0.97),in minutes,were associated with a lower risk of depression,while using social media for either 2.0-3.9 h/day(OR=1.77,95%CI:1.58-2.70)or>3.9 h/day(OR=1.67,95%CI:1.10-2.54),as well as higher levels of daytime sleepiness(OR=1.17,95%CI:1.12-1.22),were associated with a higher risk of ***:What adolescents do when they are active or sedentary may be more important than the time spent in the movement behaviors because it relates to depressive *** daytime sleepiness,promoting sports,and limiting social media use may benefit adolescents.

关键词： Accelerometry Depression Physical activity Sedentary behavior Sleep

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Cross-sectional associations between cortical thiclmess and physical activity in older adults with spontaneous memory complaints:The MAPT Study

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Journal of Sport and Health Science 2023年第3期12卷 324-332页

作者： Jérémy Raffin Yves Rolland Clara Fischer jean-Francois Mangin Audrey Gabelle bruno Vellas Philipe de Souto Barreto the MAPT/DSA Group Gérontopôle de Toulouse Institut du VieillissementCentre Hospitalo-Universitaire de ToulouseToulouse 31000France UniversitéPaul-Sabatier/Institut National de la Santéet de la Recherche Médicale UnitéMixte de Recherche 1027 Facultéde médecineUniversity of Toulouse ⅢToulouse 31000France Centre pour l'Acquisition et le Traitement des Images Multicenter Neuroimaging Platform NeurospinUniversitéParis-SaclayGif sur Yvette 91191France Memory Resources and Research Center Montpellier University HospitalMontpellier 34295France Institut National de la Santéet de la Recherche Médicale Unité1061 i-site Montpellier Universitéd'Excellence University of MontpellierMontpellier 34090France 不详

Background:Age-related changes in brain structure may constitute the starting point for cerebral function *** activity(PA)demonstrated favorable associations with total brain volume,but its relationship with cortical thickness(CT)remains *** investigated the cross-sectional associations between PA level and CT in community-dwelling people aged 70 years and ***:A total of 403 older adults aged 74.8±4.0 years(mean±SD)who underwent a baseline magnetic resonance imaging examination and who had data on PA and confounders were *** was assessed with a *** were categorized according to PA *** linear regressions were used to compare the brain CT(mm)of the inactive group(no PA at all)with 6 active groups(growing PA levels)in 34 regions of ***:Compared with inactive persons,people who achieved PA at a level of 1500-1999 metabolic equivalent task-min/week(i.e.,about6-7 h of brisk walking for exercise) and those who achieved it at 2000-2999 metabolic equivalent task-min/week(i.e.,8-11 h of brisk walking for exercise)had higher CT in the fusiform gyrus and the temporal ***,dose-response associations between PA and CT were found in the fusiform gyrus(B=0.011,SE=0.004,adj.p=0.035),the temporal pole(B=0.026,SE=0.009,adj.p=0.048),and the caudal middle frontal gyrus,the entorhinal,medial orbitofrontal,lateral occipital,and insular ***:This study demonstrates a positive association between PA level and CT in temporal areas such as the fusiform gyrus,a brain region often associated to Alzheimer’s disease in people aged 70 years and *** investigations focusing on PA type may help to fulfil remaining knowledge gaps in this field.

关键词： Alzheimer's disease Brain aging Cortical thickness Physical activity

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