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Ultra-thin Bloch-surface-wave-based reflector at telecommunication wavelength

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Photonics Research 2017年第5期5卷 494-499页

作者： R. dubey B. VOSOUGHI LAHIJANI M. HAYRINEN M. ROUSSEY M. KUITTINEN H. P. HERZIG Optics & Photonics Technology Laboratory (OPT) ecole Polytechnique Federale de Lausanne (EPFL) rue de la Maladiere 71b Institute of Photonics University of Eastern Finland

We experimentally demonstrate the optical properties of gratings engraved in a single-mode waveguide fabricated on top of a dielectric multilayer platform. The structure can be approached as a reflector for Bloch-surface-wavebased two-dimensional optical systems. The gratings have been fabricated on a thin(～λ∕25) titanium dioxide layer with a thickness of a few tens of nanometers deposited on the top of a multilayer platform. The optical properties of the gratings have been characterized in the near field with the aid of multi-heterodyne scanning nearfield optical microscopy. We investigate the surface wave's interference pattern, produced by incident and reflected light in front of the gratings. The presented gratings behave as an efficient Bloch-surface–wave-basedreflector at telecommunication wavelength.

关键词： reflector Bloch waveguide multilayer behave grating Bragg dielectric titanium fabrication

Effect of Base Width and Stiffness of the Structure on Period of Vibration of RC Framed Buildings in Seismic Analysis

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Open Journal of Earthquake Research 2015年第2期4卷 65-73页

作者： Prakash Sangamnerkar Sheo Kumar dubey Department of Civil Engineering Maulana Azad National Institute of Technology Bhopal India

Fundamental natural period of vibration T of the building is an important parameter for evaluation of seismic base shear. Empirical equations given in the Indian seismic code for the calculation of the fundamental period of a framed structure, primarily as a function of height, do not consider the effect of stiffness of the structure, base dimensions of the structure, number of panels in both the directions, amount of infill and properties of the infill. The fundamental period can be evaluated using simplified expressions found in codes, which are based on earthquake recordings in existing buildings, laboratory tests, numerical or analytical computations. These technical codes provide expressions which depend on basic parameters such as building height or number of stories. Building periods predicted by these expressions are widely used in practice although it has been observed that there is scope for further improvement in these equations since the height alone is inadequate to explain period variability. It is also known that the period of a RC frame structure differs depending on whether the longitudinal or transverse direction of the structure is considered. The aim of this study is to find the effects of building base width in both the directions, stiffness of the structure etc. and to predict the fundamental period of vibration of reinforced concrete buildings with moment resisting frames (MRF). A few examples of dynamic analysis are presented in this study to show the effect of base dimensions and stiffness of the structure in calculating the time period of the structure. And it is recommended to be incorporated in the formula for evaluating the natural period of vibration of structures.

关键词： Base Dimensions Dynamic Analysis Natural Period of Vibration Stiffness

Probiotic Screening of Lactobacilli Isolates from Uttapam Batter Fermented Supplementing with <i>Piper betle</i>L. Leaves

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Advances in Microbiology 2015年第13期5卷 858-870页

作者： Ashwini Kumar dubey Kadirvelu Jeevaratnam Department of Biochemistry and Molecular Biology Pondicherry University Puducherry India

The in vitro screening of lactobacilli isolates from uttapam batter, fermented supplementing with Piper betle L. leaves, was performed in order to select potent isolates for probiotic use. Their resistance to simulated gastric and intestinal juices as well as their adhesion to epithelial intestinal HCT-15 and vaginal HeLa cell lines were assessed and also evaluated for their immunomodulatory ability in ex vivo condition. Isolates were able to adhere as well as reduce pathogen adhesion to monolayer cell lines’ surfaces and reduced production of pro-inflammatory cytokine TNF-α in LPS treated PBMCs, while enhanced that of anti-inflammatory cytokine IL-10. The isolates exhibited properties of auto-aggregation, co-aggregation, hydrophobicity, bile salt hydrolase activity and strong antimicrobial activity against pathogenic bacteria. Thus, the different lactobacilli isolates displayed potent probiotic and immunomodulatory properties among which AJ7 and AJ82 had a great potential and may have applications in fermented foods as immunomodulatory probiotic additives.

关键词： Acid Tolerance Adhesion Immune Modulation Lactobacilli Probiotic

成虫体型大小驱动六斑月瓢虫性间相互选择(英文)

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昆虫学报 2016年第2期59卷 209-218页

作者： Ankita dubey OMKAR Geetanjali MISHRA Department of Zoology University of Lucknow

【目的】配偶选择是性选择的中心过程,当繁殖成本发生波动和配偶质量存在差异时,传统的性别作用也随之不同。为了验证在某些条件下雄性也可以像雌性一样进行选择,我们研究了雄性和雌性六斑月瓢虫Menochilus sexmaculatus(Fabricius)的... 详细信息

【目的】配偶选择是性选择的中心过程,当繁殖成本发生波动和配偶质量存在差异时,传统的性别作用也随之不同。为了验证在某些条件下雄性也可以像雌性一样进行选择,我们研究了雄性和雌性六斑月瓢虫Menochilus sexmaculatus(Fabricius)的交配成功率与作为适合度指标的成虫体型大小之间的关系。【方法】从初始种群中随机选择体型小和体型大的两性成虫,进行雄性和雌性配偶选择试验。并对成功交配的各个配对组的后代也进行配偶选择试验,测试其交配成功率。【结果】配偶选择试验结果表明,在雄性和雌性交配试验中交配的成功取决于体型大小。雄性根据其品质即体型大小这一繁殖力指标对雌性进行区分。同样,在雌性交配试验中体型大的雄虫比体型小的雄虫交配成功率高。无论亲本体型如何,体型大的雌虫都比体型小的雌虫产卵量高;不过,体型大小不影响卵的存活力。体型大的亲本的后代比体型小的亲本的后代发育更快,寿命更长,但是将其与来自初始种群的后代进行配偶选择时,它们在性合意(sexual desirability)或竞争力方面没有表现任何优势。【结论】六斑月瓢虫中存在以体型大小为目的性状的相互配偶选择。

关键词：六斑月瓢虫适合度配偶选择交配成功繁殖产量性竞争

Multidimensional QSAR Modeling of Amprenavir Derivatives as HIV-Protease Inhibitors

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Open Journal of Medicinal Chemistry 2011年第1期1卷 1-15页

作者： Sonal dubey G. Gowtham KLE University"s College of Pharmacy

A computational study has been performed on a series of 55 compounds having (S)-N-(3-(N-(cyclopean- tylmethyl)substituted-phenylsulfonamido)-2-hydroxypropyl)acetamide backbone as HIV-1 protease inhibitors. Various combinations of these specific inhibitors fragments were formed by breaking them at central alicyclic single bonds, while retaining the core. Standard Topomer 3D models were automatically constructed for each fragment, and a set of steric and electrostatic fields was generated for each set of topomers. The models generated showed r2 of 0.811 and crossvalidated r2 (q2) of 0.608. The other method used were Quasar and Raptor based on receptor-modelling concept (6D-QSAR) and this explicitly allows for the simulation of the induced fit, that yielded r2 of 0.574, cross-validated r2 (q2) of 0.504 and predictive r2 (q2) of 0.895 averaged over 200 models. This study has suggested the various type of substituent that can be attached to the core. The information obtained from these 3-D contour maps can be used for the design of amprenavir analogs possessing better protease inhibitory activity.

关键词： 3D-QSAR 5D-QSAR 6D-QSAR Topmer CoMFA Quasar Raptor

近20年印度北阿坎德邦奈尼塔尔地区农业面积变化

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Journal of Resources and Ecology 2023年第5期14卷 983-990页

作者： Saurabh PARGAIEN Rishi PRAKASH Ved Prakash dubey 格拉菲克时代电子与通信工程系德拉敦248002印度格拉菲克时代山地大学计算机科学与工程系德拉敦248002印度

本研究对印度北阿坎德邦奈尼塔尔地区的农业用地进行了时间序列分析。该研究基于Landsat5,Landsat7and Landsat8卫星图像数据,使用随机森林分类器对该区域近21年(2000–2021年)的农业和非农业土地进行分类。陆地卫星图像使用谷歌地球引... 详细信息

本研究对印度北阿坎德邦奈尼塔尔地区的农业用地进行了时间序列分析。该研究基于Landsat5,Landsat7and Landsat8卫星图像数据,使用随机森林分类器对该区域近21年(2000–2021年)的农业和非农业土地进行分类。陆地卫星图像使用谷歌地球引擎(GEE)平台进行处理,随机森林分类器的选择则是基于随机森林(RF)、支持向量机(SVM)和分类与回归树(CART)之间的比较分析。对总体准确度、用户准确度、生产者准确度和Kappa系数进行了评估,以确定研究区域的最佳分类器。结果表明,2021年RF、SVM和CART的总体准确率分别为96.38%、94.44%和91.94%;类似地,RF、SVM和CART的Kappa系数分别为0.96、0.89和0.81。陆地卫星在农业和非农业地区的分类图像显示,该区域在21年间(2000–2021年)农业用地减少了4.71%。该研究还表明,过去4年(即2018–2021年)该区域农业面积下降幅度最大。本研究对于发展中国家了解农用地变化并采取适当措施以保护该地区的动植物非常重要。

关键词：机器学习土地分类谷歌地球引擎

Broadcasting with Controlled Redundancy and Improved Localization in Wireless Sensor Networks

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Journal of Electronic Science and Technology 2013年第4期11卷 404-407页

作者： Tarun dubey Om Prakash Sahu the Department of Electronics and Communication Engineering National Institute of Technology

Wireless sensor networks （WSNs） consist of sensor nodes that broadcast a message within a network. Efficient broadcasting is a key requirement in sensor networks and has been a focal point of research over the last few years. There are many challenging tasks in the network, including redundancy control and sensor node localization that mainly depend on broadcasting. In this paper, we propose a broadcasting algorithm to control redundancy and improve localization （BACRIL） in WSNs. The proposed algorithm incorporates the benefits of the gossip protocol for optimizing message broadcasting within the network. Simulation results show a controlled level of redundancy, which is up to 57.6% if the number of sensor nodes deployed in a 500 m×500 m area are increased from 50 to 500.

关键词： Broadcast gossip localization nodedensity redundancy wireless sensor networks.

肝细胞癌MRI影像学特征、炎性指标、KI67、CD34与微血管侵犯的相关性研究

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肝细胞癌MRI影像学特征、炎性指标、KI67、CD34与微血管侵犯的相...

作者： Hitashi dubey 昆明医科大学

学位级别：硕士

[背景]尽管目前有研究表明微血管浸润（microvascular invasion,MVI）阳性与KI67、CD34和影像学特征之间存在相关性,但研究结果并不完全一致,且与MVI不同分级之间是否相关,目前尚无研究。此外,我们前期研究显示血清炎性指标与Edmondson... 详细信息

[背景]尽管目前有研究表明微血管浸润（microvascular invasion,MVI）阳性与KI67、CD34和影像学特征之间存在相关性,但研究结果并不完全一致,且与MVI不同分级之间是否相关,目前尚无研究。此外,我们前期研究显示血清炎性指标与Edmondson病理分级存在相关性,是否与MVI分级相关尚不清楚.[目的]因此本研究探讨肝细胞癌中MRI影像学特征、血清炎症指标、KI67、CD34和病理组织学分级与MVI分级的相关性。[方法]收集2017年1月到2022年1月术后病理证实为肝细胞肝癌,且具有病理分级和MVI分级的患者血清炎症标志物（ALR、NLR、APRI）、免疫组化指标（CD34、KI67）、术前MRI影像特征。研究对象分为MVI 0级、1级以及2级三组。采用Wilcoxon秩和检验及卡方检验比较三组患者的组间差异,再进一步行Spearman秩相关分析。[结果]最终纳入173名患者,MVI0级（71例）、MVI1级（57例）和MVI2级（45例）。结果显示CD34（P=0.030）和组织学分级（P=0.002）在不同MVI分级间存在统计学差异,而三组患者的性别、KI67以及肝叶受累程度、瘤内出血、瘤内坏死、肿瘤生长模式、肿瘤数量、炎性指标等指标无统计学差异（P＞0.05）。进一步Spearman秩相关分析显示组织学分级与MVI分级之间存在低度相关（r=0.266,P＜0.001）。[结论]尽管KI67与肿瘤增殖相关,但与MVI不同分级间未见相关性;CD34蛋白是一种高度糖基化修饰的跨膜糖蛋白,和肿瘤的血管生成、毛细血管密度密切相关,不同MVI分级间CD34存在差异。Edmondson病理分级与MVI分级存在低度正相关,组织学分级越高,MVI的分级也越高。

关键词：肝细胞癌 MVI KI67 CD34 影像学特征

A Practical Solution for Location Estimation in Manually Deployed Wireless Sensor Networks

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Wireless Sensor Network 2011年第4期3卷 117-120页

作者： Om Prakash Sahu Tarun dubey Department of Electronics and Communication Engineering National Institute of Technology Department of Electronics and Communication Engineering Invertis University

This paper addresses the existing research and adds another aspect of functionality by incorporating pertinent sensor nodes to provide a dynamic location discovery and estimation. The software used provides an easy graphical user interface to visualize a particular location in accordance with geographical latitude and longitude. A simple real time location estimation technique is worked out for wireless sensor networks based on manual deployment of sensors. The proposed scheme finds more efficient solutions with less quantity of sensors as compared to existing deployment schemes. The set up is evaluated exclusively in real environments using IRIS sensor nodes supported by a global positioning system module to provide visualization of an outdoor location. The results are offered by Google Earth application.

关键词： Wireless Sensor Network (WSN) Global Positioning System (GPS) Localization Sensor Node IRIS Sensor