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Detection of internal crack growth in polyethylene pipe using guided wave ultrasonic testing

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 319-329页

作者： jay Kumar Shah Hao Wang Said El-Hawwat Centre of Advanced Infrastructure and Transportation RutgersThe State University of New JerseyNJ 08854USA Department of Civil and Environmental Engineering RutgersThe State University of New JerseyNJ 08854USA

Despite the success of guided wave ultrasonic inspection for internal defect detection in steel pipes,its application on polyethylene(PE)pipe remains relatively *** growth of internal cracks in PE pipe severely affects its pressure-holding capacity,hence the early detection of internal cracks is crucial for effective pipeline maintenance *** study extends the scope of guided wave-based ultrasonic testing to detect the growth of internal cracks in a natural gas distribution PE *** experiments and a finite element model were planned to study the wave-crack interaction at different stages of axially oriented internal crack growth with a piezoceramic transducer-based setup arranged in a pitch-catch *** dispersion analysis supplemented with preliminary experiments was performed to isolate the optimal inspection frequency,leading to the selection of the T(0,1)mode at 50-kHz for the investigation.A transmission index based on the energy of the T(0,1)mode was developed to trace the extent of simulated crack *** findings revealed an inverse linear correlation between the transmission index and the crack depth for crack growth beyond 20%crack depth.

关键词： polyethylene pipes internal cracks guided wave ultrasonic testing torsional modes finite element modeling

Carbene chemistry for unnatural biosynthesis

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Science China(Life Sciences) 2024年第1期67卷 204-207页

作者： Jing Huang jay D.Keasling Department of Chemical and Biomolecular Engineering University of CaliforniaBerkeley 94720USA Joint BioEnergy Institute Lawrence Berkeley National LaboratoryEmeryville 94608USA Biological Systems and Engineering Division Lawrence Berkeley National LaboratoryBerkeley 94720USA Novo Nordisk Foundation Center for Biosustainability Technical University of DenmarkKongens Lyngby 2800Denmark Department of Bioengineering University of CaliforniaBerkeley 94720USA Synthetic Biochemistry Center Institute for Synthetic BiologyShenzhen Institutes for Advanced TechnologiesShenzhen 518055China

Previously,chemists working in synthesis were jealous of biologists since the enzymes found in nature usually exhibited great catalytic properties(e.g.,high catalytic efficiency,excellent selectivity such as substrate selectivity,regioselectivity and stereoselectivity).However,biological systems lack many counterparts of reactions widely used in chemical synthesis.

关键词： synthesis selectivity catalytic

Clinical studies in COVID-related olfactory disorders:Review of an institutional experience

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第2期10卷 129-136页

作者： Theresa Tharakan Dorina Kallogjeri jay F.Piccirillo Department of Otolaryngology-Head and Neck Surgery Clinical Outcomes Research OfficeSchool of MedicineWashington University in St LouisSt LouisMissouriUSA

Objective:To share a single institutional experience with clinical research on COVID-related olfactory dysfunction(OD).Data Source/Method:Narrative review of published original data and ongoing clinical trials on COVID-related OD at Washington University from 2020 to ***:There were three new diagnostic-/patient-reported outcome measures developed and *** report five clinical trials of interventions for COVID-related olfactory disorders:combined Visual-Olfactory Training(VOLT)with patient-preferred scents versus standard olfactory training(VOLT trial),oral gabapentin versus placebo(Gabapentin for the Relief of Acquired Chemosensory Experience trial),nasal theophylline irrigations versus placebo(Smell Changes and Efficacy of Nasal Theophylline trial),stellate ganglion block(single-arm),and mindfulness-based stress reduction(MBSR)versus lifestyle intervention(MBSR trial).Conclusions:Initial intervention trials for COVID-related OD have shown potential for improving subjective and objective olfactory ***,there remains no gold standard treatment that definitively outperforms placebo in controlled ***,continued investigation of novel therapeutic strategies for COVID-related OD is necessary to maximize olfactory outcomes for affected patients.

关键词： chemosensory disorders COVID olfactory dysfunction

Microglial dysfunction and genetic risk for neurodegenerative disease

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Neural Regeneration Research 2025年第5期20卷 1401-1402页

作者： Debra S.MacDonald jay Penney Department of Biomedical Sciences AVCUniversity of Prince Edward IslandCharlottetownPECanada

Neurodegenerative disorders such as Alzheimer's and Parkinson's diseases a re increasing in prevalence as world populations *** tremendous progress has been made,our understanding of the mechanisms that underlie the development of these diseases remains far from com *** troubling,despite the growing emotional and financial toll being to ken by neurodegenerative disorders,existing treatment options are limited almost exclusively to those that help manage symptoms but that lack the ability to alter the progression of the disease(Liu et al.,2022).

关键词： degenerative diseases

Chordoma in Nasopharynx in a 70-Year-Old Female: A Rare Occurence

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International Journal of Otolaryngology and Head & Neck Surgery 2014年第6期3卷 342-346页

作者： Bhaskar Mitra Subhalakshmi Sengupta Anshita Rai jay mehta Aruna Rai Quader Subhendu Roy Anita Borges Drs. Tribedi & Roy Diagnostic Laboratory Kolkata India

The nasopharynx is an unusual site for extraosseous chordoma. The characteristic histology and immunohistochemistry confirmed the diagnosis. The behaviour of this tumour is locally aggressive. We report a case of naso... 详细信息

关键词： Chordoma Nasopharyngeal Tumours Notochord

《第28届急性疾病质量倡议工作组共识报告:脓毒症相关急性肾损伤》解读

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中华肾脏病杂志 2024年第3期40卷 237-244页

作者：刘彩虹 jay Koyner 赵宇亮付平四川大学华西医院肾脏内科、四川大学华西医院肾脏病研究所成都610041 芝加哥大学内科学系芝加哥60607

脓毒症相关急性肾损伤(sepsis associated acute kidney injury,SA-AKI)被定义为脓毒症背景下急性肾损伤(acute kidney injury,AKI)的存在。在遗传易感性的背景下,脓毒症可通过多种机制导致SA-AKI的发生,基于病理生理机制的差异,SA-AKI... 详细信息

脓毒症相关急性肾损伤(sepsis associated acute kidney injury,SA-AKI)被定义为脓毒症背景下急性肾损伤(acute kidney injury,AKI)的存在。在遗传易感性的背景下,脓毒症可通过多种机制导致SA-AKI的发生,基于病理生理机制的差异,SA-AKI归属于不同的“内型”,且表现为不同的“亚表型”。生物标志物和预测模型的结合具备早期识别AKI高风险患者和明确SA-AKI“内型”的潜力。容量复苏及血液净化是SA-AKI治疗的优化策略。此外,基于儿童的SA-AKI临床研究值得期待。

关键词：脓毒症急性肾损伤诊断急性疾病质量倡议专家共识

Uncovering the dominant contribution of intermediate volatility compounds in secondary organic aerosol formation from biomass-burning emissions

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National Science Review 2024年第3期11卷 150-158页

作者： Kun Li Jun Zhang David M.Bell Tiantian Wang Houssni Lamkaddam Tianqu Cui Lu Qi Mihnea Surdu Dongyu Wang Lin Du Imad El Haddad jay G.Slowik Andre S.H.Prevot Environment Research Institute Shandong University Laboratory of Atmospheric Chemistry Paul Scherrer Institute

Organic vapors from biomass burning are a major source of secondary organic aerosols(SOAs). Previous smog chamber studies found that the SOA contributors in biomass-burning emissions are mainly volatile organic compounds(VOCs). While intermediate volatility organic compounds(IVOCs) are efficient SOA precursors and contribute a considerable fraction of biomass-burning emissions, their contribution to SOA formation has not been directly observed. Here, by deploying a newly-developed oxidation flow reactor to study SOA formation from wood burning, we find that IVOCs can contribute ～70% of the formed SOA, i.e.>2 times more than VOCs. This previously missing SOA fraction is interpreted to be due to the high wall losses of semi-volatile oxidation products of IVOCs in smog chambers. The finding in this study reveals that SOA production from biomass burning is much higher than previously thought, and highlights the urgent need for more research on the IVOCs from biomass burning and potentially other emission sources.

关键词： atmospheric chemistry biomass burning secondary organic aerosol intermediate volatility organic compounds

Epidemiologic investigation of pediatric distal humerus fractures: An American insurance claims database study

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World Journal of Orthopedics 2024年第1期15卷 52-60页

作者： Kyle jay Klahs Jake E Dertinger Grant T Mello Kevin Thapa Alexis B Sandler E'Stephan J Jesus Garcia Nata Parnes Department of Orthopaedic Surgery Texas Tech University Health Sciences-El PasoEl PasoTX 79905United States Medical School California Health Sciences University College of Osteopathic MedicineClovisCA 93611United States Undergraduate School Binghampton UniversityVestalNY 13902United States Department of Orthopaedic Surgery William Beaumont Army Medical CenterFort BlissTX 79918United States Department of Orthopaedic Surgery Carthage Area HospitalCarthageNY 13619United States

BACKGROUND Distal humerus elbow fractures are one of the most common traumatic fractures seen in pediatric patients and present as three main types:Supracondylar(SC),lateral condyle(LC),and medial epicondyle(ME)*** To evaluate the epidemiology of pediatric distal humerus fractures(SC,LC,and ME)from an American insurance claims *** A retrospective review was performed on patients 17 years and younger with the ICD 9 and 10 codes for SC,LC and ME fractures based on the IBM Truven MarketScan®Commercial and IBM Truven MarketScan Medicare Supplemental *** from 2015 to 2020 were queried for treatments,patient age,sex,length of hospitalization,and *** A total of 1133 SC,154 LC,and 124 ME fractures were *** fractures had the highest percentage of operation at 83%,followed by LC(78%)and ME fractures(41%).Male patients were,on average,older than female patients for both SC and ME *** In the insurance claims databases used,SC fractures were the most reported,followed by LC fractures,and finally ME *** was identified to be a factor for how a pediatric distal humerus fractures,with patients with SC and LC fractures being younger than those with ME *** peak age per injury per sex was similar to reported historic central tendencies,despite reported trends for younger physiologic development.

关键词： Supracondylar humerus fracture Lateral condyle fracture Medial epicondyle fracture Pediatric elbow Truven Epidemiology

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创造吧,我们的星球

疯狂英语（新悦读） 2024年第3期 41-41,75页

作者： jay Sivanesan Paranam 不详

让我们居住的星球变得更好,你我都可贡献一分力量!Max Han is helping to bring about environmental changes through YUFE(Youths United for Earth). When he was 19, Han co-founded the grassroots organization with his friend, ... 详细信息

关键词： planet roots helping