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Sudden cardiac death in anabolic androgenic steroids abuse: case report and literature review

Forensic Sciences Research 2019年第3期4卷 267-273页

作者： Ana Isabel Hernández-Guerra javier tapia Luis Manuel Menéndez-Quintanal Joaquín S.Lucena Histopathology Service National Institute of Toxicology and Forensic Sciences(NITFS)Canary Islands DepartmentTenerifeSpain Forensic Pathology Service Institute of Legal Medicine and Forensic Sciences(ILMFS)Las Palmas de Gran CanariaSpain Chemistry Service NITFSCanary Islands DepartmentTenerifeSpain Forensic Pathology Service ILMFSSevilleSpain

Anabolic androgenic steroids (AAS) have several adverse effects on the cardiovascular system that may lead to a sudden cardiac death (SCD).We herein report a case involving a 24-year-old male,AAS abuser with intramuscular delivery in the 6 months before,who suffered a cardiorespiratory arrest at home's bathtub when returning from New Year's party.A forensic autopsy was performed according to the guidelines of the Association for European Cardiovascular Pathology (AECVP).The body showed hypertrophy of skeletal musculature,with low amount of subcutaneous fat and no signs of injury (body mass index,BMh 26.8 kg/m^(2)).On internal examination,there were multiorgan congestion,acute pulmonary edema,and cardiomegaly (420 g) with severe coronary atherosclerosis and superimposed acute occlusive thrombosis at the left main trunk and left anterior *** of scarring were located at the intersection between the posterior wall and the posterior third of the septum (postero-septal).At histology,acute myocardial infarction at the anterior third of the septum and the anterior wall,and subacute myocardial infarction at apical septum and apical posterior wall were *** findings were small intramyocardial vessel disease and myocytes *** analysis in blood showed ethanol ((0.90 ±0.05) g/L),stanazolol (11.31 μg/L),nandrolone (2.05μg/L) and testosterone (<1.00μg/L).When confronted with a sudden death in a young athlete we must pay attention to the physical phenotype that may suggest AAS abuse and perform a detailed examination of the *** analysis is a key to establish the relationship between SCD and AAS abuse.

关键词： Forensic sciences forensic pathology anabolic androgenic steroids(AAS) sudden cardiac death autopsy cardiac pathology toxicology

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Smoking is not associated with nonalcoholic fatty liver disease

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World Journal of Gastroenterology 2006年第32期12卷 5196-5200页

作者： Norberto C Chavez-tapia javier Lizardi-Cervera Oliver Perez-Bautista Martha H Ramos-Ostos Misael Uribe Departments of Gastroenterology and Internal Medicine. Medica Sur Clinic and Foundation Mexico City Mexico

AIM： To analyze the relationship between smoking and nonalcoholic fatty liver disease （NAFLD）. METHODS： This is a cross-sectional study of a healthy population, carried out in a check-up unit of a university hospital in Mexico City. We enrolled 933 subjects, 368 current smokers （cases） and 565 persons who had never smoked （controls）. Demographic, metabolic and biochemical variables were measured in the two groups. NAFLD was determined by ultrasound and metabolic syndrome according to ATPⅢ. RESULTS： A total of 548 men （205 cases and 343 controls） and 337 women （114 cases and 223 controls） were included in the analysis. Statistical differences between cases and controls were observed only in high blood pressure prevalence （6.6% vs 11.3%, P〈0.05; cases and controls respectively）, high-density lipoproteins （1.00±0.26 vs 1.06±0.28 mmol/L, P 〈 0.005）, triglycerides （2.18±1.49 vs 1.84±1.1 mmol/L, P〈0.001）, and erythrocyte sedimentation rate （11.3±9.3 vs 13.5±11.9 mm/h, P〈0.001）. No differences were observed in the prevalence of NAFLD （22.27% vs 29.68%, P = NS） and metabolic syndrome （41.69% vs 36.74%, P = NS）. Univariate analysis showed that smoking was not a risk factor for NAFLD （OR = 0.89, 95% CI 0.65-1.21）. CONCLUSION： No differences in NAFLD prevalence were observed between current smokers and nonsmokers, and furthermore, no differences were observed in heavy smokers （more than 20 packs/year）, indicating that there js no relationship between smoking and NAFLD.

关键词： Smoking Nonalcoholic fatty liver disease Metabolic syndrome

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Prevalence of meeting 24-Hour Movement Guidelines from pre-school to adolescence: A systematic review and meta-analysis including 387,437 participants and 23 countries

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Journal of Sport and Health Science 2022年第4期11卷 427-437页

作者： Miguel Angel tapia-Serrano javier Sevil-Serrano Pedro Antonio Sanchez-Miguel Jose Francisco Lopez-Gil Mark STremblay Antonio Garcıa-Hermoso Department of Didactics of Musical Plastic and Body ExpressionFaculty of Teaching TrainingUniversity of ExtremaduraAvenida de la UniversidadS/NCaceres 10071Spain Department of Physical Activity and Sport Faculty of Sport ScienceUniversity of Murcia(UM)San Javier 30720Spain Healthy Active Living and Obesity Research Group Children’s Hospital of Eastern Ontario(CHEO)Research InstituteOttawaON K1H 8L1Canada Navarrabiomed Public University of Navarra(UPNA)Health Research Institute of Navarra(IdiSNA)Navarra Hospital Complex(CHN)Pamplona 310008Spaia

Background:Meeting the 24-Hour Movement Guidelines(physical activity,screen time,and sleep duration) has been associated with positive health ***,there are no previous meta-analyses that have examined the overall adherence to the 24-Hour Movement Guidelines from pre-school to adolescence across the ***,the main purpose of this systematic review and meta-analysis was to examine the overall(non)adherence to the 24-Hour Movement Guidelines among preschoolers,children,and adolescents ***:Four electronic databases(MEDLINE,Scopus,Web of Science,and Cochrane Database of Systematic Reviews) were searched for quantitative studies published in Spanish and English between January 2016 and May *** that were conducted with apparently healthy participants and reported the overall(non)adherence to the 24-Hour Movement Guidelines in preschoolers and/or children and/or adolescents were ***:Sixty-three studies comprising 387,437 individuals(51% girls) aged 3-18 years from 23 countries were ***,7.12%(95%confidence interval(95%CI):6.45%-7.78%) of youth met all three 24-Hour Movement Guidelines,and 19.21%(95%CI:16.73%-21.69%)met none of the 3 *** sex,adherence to all recommendations was significantly lower in girls(3.75%,95%CI:3.23%-4.27%) than in boys(6.89%,95%CI:5.89%-7.89%)(p <0.001).However,there were no sex differences regarding adherence to any of the 3 individual recommendations(girls,15.66%,95%CI:8.40%-22.92%;boys,12.95%,95%CI:6.57%-19.33%).In terms of age group,adherence to the 3 recommendations was 11.26%(95%CI:8.68%-13.84%),10.31%(95%CI:7.49%-13.12%),and 2.68%(95%CI:1.78%-3.58%) in preschoolers,children,and adolescents,***,8.81%(95%CI:5.97%-11.64%) of preschoolers,15.57%(95%CI:11.60%-19.54%) of children,and 28.59%(95%CI:22.42%-34.75%) of adolescents did not meet any of the *** America was the region with the lowest adherence(all:2.93%;none:3

关键词： Exercise Lifestyle Movement behaviors Sedentary behaviors Youth

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World Journal of Gastroenterology 2013年第30期19卷 4877-4886页

作者： María Gómez-García Maria José Cabello-tapia Antonio Damián Sánchez-Capilla javier De Teresa-Galván Eduardo Redondo-Cerezo Inflammatory Bowel Disease Unit Department of GastroenterologyUniversity Hospital Virgen de Las Nieves18014 GranadaSpain Department of Gastroenterology University Hospital Virgen de Las Nieves18014 GranadaSpain Endoscopy Unit Department of GastroenterologyUniversity Hospital Virgen de Las Nieves18014 GranadaSpain

AIM:To investigate the incidence of neoplasms in inflammatory bowel disease(IBD)patients and the potential causative role of ***:We performed an observational descriptive study comparing the incidence of malignancies in IBD patients treated with thiopurines and patients not treated with these *** included 812 patients which were divided in two groups depending on whether they have received thiopurines or *** have studied basal characteristics of both groups(age when the disease was diagnosed,sex,type of IBD,etc.)and treatments received(Azathioprine,mercaptopurine,infliximab,adalimumab or other immunomodulators),as well as neoplasms *** analysis was performed with the student t test,χ 2 test or Wilcoxon exact test as appropriate.A logistic regression analysis was performed as multivariate *** significance was establish at P values of less than 0.05,and 95%CI were used for the odds ***:Among 812 patients included,429(52.83%)have received thiopurines:79.5% azathioprine,14% mercaptopurine and 6.5% both drugs.44.76% of patients treated with thiopurines and 46,48% of patients who did not receive this treatment were women(P > 0.05).The proportion of ulcerative colitis patients treated with thiopurines was 30.3% compare to 66.67% of patients not treated(P < 0.001).Mean azathioprine dose was 123.79 ± 36.5 mg/d(range:50-250 mg/d),mean usage time was 72.16 ± 55.7 mo(range:1-300 mo)and the accumulated dose along this time was 274.32 ± 233.5 g(1.5-1350 g).With respect to mercaptopurine,mean dose was 74.7 ± 23.9 mg/d(range:25-150 mg/d),mean usage time of 23.37 ± 27.6 mo(range:1-118 mo),and the accumulated dose along this time was 52.2 ± 63.5 g(range:1.5-243 g).Thiopurine S-methyltransferase activity was tested in 66% of patients treated with thiopurines,among which 98.2% had an intermediate or high *** the patients treated with thiopurines,27.27%(112 patients)and 11.66%(50 patients)received treatment

关键词： Malignancy Neoplasm Inflammatory bowel disease Crohn’s disease Ulcerative colitis Thiopurines Azathioprine Mercaptopurine

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Microbiological Identification of Atmospheric Particles in Hermosillo, Sonora, México

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Journal of Environmental Protection 2014年第5期5卷 376-386页

作者： Santos-Romo Alvaro Sau-Acosta Nancy Janeth Certucha-Barragán María Teresa Almendáriz-tapia Francisco javier Monge-Amaya Onofre Hernández-López Jorge Zepeda-Ibarra Joel Department of Chemical Engineering & Metallurgy within the Engineering Division of the University of Sonora Hermosillo Mexico Nortwest BiologicalInvestigation Centre Hermosillo Mexico Urban Development and Ecology General Coordination of Infrastructure Municipal Institute of Ecology Hermosillo Mexico

The air quality in many cities has been deteriorating and affecting population’s health. Airborne particles can block the defense mechanisms of respiratory system and may lead biological elements such as pollen, bacteria, fungi and viruses into the lungs. This paper presents the study of biologically contaminated air in the city of Hermosillo, analyzing filters containing particulate matter with a diameter equal or less than 10 micrometers (PM10) and Total Suspended Particles (TSP). Three sampling periods were analyzed during 2011. Samples taken from the filters were placed in tubes containing nutritive broth BHI (Brain Heart Infusion) and incubated at 37 °C for 24 hours. The identification of the isolated microorganisms was done by a biochemical test recommended in Bergey’s Manual. Results showed a high bacteria concentration in the presence of microorganisms such as Klebsiella pneumoniae sub pneumoniae, Citrobacter, Enterococcus faecalis, Proteus penneri, Butiauxellaagrestis, Salmonella paratyphi A and Enterobacter sacazakii. When bacterial concentration was analyzed separately, the lowest number of bacteria was observed during February for the south location and in August for the north location. The highest degree of bacterial air pollution was found in the central area of the city.

关键词： Air Pollution Airborne Particles Bacteria

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Improving Compost Process Efficiency by Leachates Inoculation and Shredding of the Organic Fraction of Municipal Solid Waste at Bordo Poniente Composting Plant,Mexico City

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Journal of Environmental Science and Engineering(A) 2021年第5期10卷 177-183页

作者： Francisco javier Barrón-Santos Ma.Eugenia Gutiérrez-Castillo Luis Raúl Tovar-Gálvez Ma.Teresa Núñez-Cardona Ricardo Estrada-Núñez Claudia Rodríguez tapia Alfonso Espitia-Cabrera Departamento de Posgrado Salud OcupacionalSeguridad e HigieneEscuela Nacional de Medicina y HomeopatíaInstituto Politécnico NacionalCiudad de México 07320México Departamento de Biociencias e Ingeniería Centro Interdisciplinario de Investigaciones y Estudios sobre Medio Ambiente y DesarrolloInstituto Politécnico NacionalCiudad de México 07340México Departamento El Hombre y su Ambiente Universidad Autónoma Metropolitana XochimilcoCiudad de México 04960México Secretaría de Obras y Servicios Gobierno de la Ciudad de MéxicoCiudad de México 06000México Unidad Profesional Interdisciplinaria de Biotecnología Instituto Politécnico NacionalCiudad de México 07340México Departamento de Energía Universidad Autónoma Metropolitana AzcapotzalcoCiudad de México 02200México

Management of MSW(Municipal Solid Waste)is a major downside in most of the biggest *** composting of the organic fraction of MSW is one of the oldest and simplest ways of organic waste *** is a self-heating biological conversion that generates appropriate finished merchandise such as soil conditioner or *** City generates about 12,500 ton/day of MSW,44%of it is food scraps and yard trimmings which are the OFMSW(Organic Fraction of Municipal Solid Waste),2,500 ton/day of it is composted at the BPCP(Bordo Poniente Composting Plant)yielding 500 ton/day of *** purpose of this study was to evaluate three treatments to accelerate the composting process,so eventually the city could increase the amount of the OFMSW at *** compared three different treatments;one of them showed a significant reduction in time of the composting process(p≤0.05)i.e.,it took less time to reach the thermophilic stage,maturity and stabilization *** was achieved at 35 days and 60 days to *** conclude that shredding the feedstock plus leachate inoculum addition at the beginning of the process,reduces the composting time in about 61%with respect to the time it takes at the BPCP,where lasted 90 days.

关键词： Composting organic fraction municipal solid waste inoculum leachates size particle

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Turbo-taxonomy to assemble a megadiverse lichen genus:seventy new species of Cora(Basidiomycota:Agaricales:Hygrophoraceae),honouring David Leslie Hawksworth’s seventieth birthday

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Fungal Diversity 2017年第3期84卷 139-207页

作者： Robert Lücking Manuela Dal Forno Bibiana Moncada Luis Fernando Coca Leidy Yasmín Vargas-Mendoza André Aptroot Laura Juliana Arias Betty Besal Frank Bungartz Diego Mauricio Cabrera-Amaya Marcela E.S.Cáceres José Luis Chaves Sionara Eliasaro Martha Cecilia Gutiérrez Jesús E.Hernández Marin María de los Ángeles Herrera-Campos María E.Holgado-Rojas Harald Jonitz Martin Kukwa Fabiane Lucheta Santiago Madriñán Marcelo Pinto Marcelli Suzana Maria de Azevedo Martins Joel A.Mercado-Díaz Jorge Alberto Molina Eduardo A.Morales Peter R.Nelson Freddy Nugra Francisco Ortega Telma Paredes Ayda Lucía Patiño Rouchi Nadine Peláez-Pulido Rosa Emilia Pérez Pérez Gary B.Perlmutter Eimy Rivas-Plata javier Robayo Camilo Rodríguez Diego Fernando Simijaca Edier Soto-Medina Adriano Afonso Spielmann Alejandra Suárez-Corredor Jean-Marc Torres Carlos Alberto Vargas Alba Yánez-Ayabaca Gothamie Weerakoon Karina Wilk Marcela Celis Pacheco Mauricio Diazgranados Grischa Brokamp Thomas Borsch Patrick M.Gillevet Masoumeh Sikaroodi James D.Lawrey Botanical Garden and Botanical Museum Berlin KöniginLuise-Straße 6-814195 BerlinGermany Science Education The Field Museum1400 South Lake ShoreChicagoIL 60605USA Department of Botany Smithsonian InstitutionNational Museum of Natural History10th St Constitution Ave NWWashingtonDC 20560USA Department of Environmental Science and Policy George Mason UniversityFairfaxVA 22030-4444USA Licenciatura en Biologı´a Universidad Distrital Francisco Jose´de CaldasCra.4 No.26D-54Torre de LaboratoriosHerbarioBogota´D.C.Colombia Herbario Universidad de Caldas(FAUC) Edificio BicentenarioCalle 65No.26-10ManizalesA.A.275CaldasColombia ABL Herbarium G.v.d.Veenstraat 1073762 XK SoestThe Netherlands Biologı´a Universidad del Quindı´oCarrera 15 Calle 12 NorteArmeniaQuindı´oColombia 120 Chavis Avenue LexingtonVA 24450USA Charles Darwin Foundation Puerto AyoraSanta Cruz IslandGala´pagosEcuador Schedestraße 8 53113 BonnGermany Jardı´n Bota´nico de Bogota´Jose´Celestino Mutis Avenida Calle 63 No.68-95Bogota´D.C.Colombia Departamento de Biocieˆncias Universidade Federal de SergipeAvenida Vereador Olı´mpio Grandes/n.ItabaianaCEP:49.500-000 SergipeBrazil Laboratorio de Hongos Instituto Nacional de Biodiversidad(INBio)Apdo.22-3100Santo Domingo de HerediaCosta Rica Departamento de Botaˆnica Universidade Federal do Parana´Campus Polite´cnicoSetor de Cieˆncias Biolo´gicasAv.Cel.Francisco H.dos Santoss/nJardim das Ame´ricas81531-980 CuritibaPRBrazil Ingenierı´a Ambiental Universidad Distrital Francisco Jose´de CaldasCarrera 5 Este No.15-82Av.CircumvalarBogota´D.C.Colombia Instituto Experimental Jardı´n Bota´nico Dr.Tobı´as Lasser Centro de Investigacio´n y DesarrolloUniversidad Central de VenezuelaAve.Salvador AllendeJardı´n Bota´nico de CaracasApartado#2156Caracas 1010-AVenezuela Departamento de Bota´nica Instituto de Biologı´aUniversidad Nacional Auto´noma de Me´xicoApartado Postal 70-36704510 Ciudad De Me´xicoMexico Facultad de Ciencias Escuela Profesional de Biologı´aUniv

Following a large-scale phylogenetic study of the lichenized genus Cora(Basidiomycota:Agaricales:Hygrophoraceae),we formally describe 70 new species,honouring the seventieth birthday of David Leslie Hawksworth,one of the preeminent figures in mycology and lichenology in the past 50 *** on an updated phylogeny using the ITS fungal barcoding locus,we now recognize 189 taxa in a genus that until recently was considered to represent a single species;including this contribution,92 of these are formally recognized,including five taxa based on historical names or collections that have not been *** of Cora can be recognized by a combination of morphological(size,colour,lobe configuration,surface hairs,hymenophore size and shape),anatomical(thallus thickness,cortex structure,photobiont type,hyphal papillae),and ecogeographical features(substrate,habitat,distribution),and a keytable allowing the identification of all accepted taxa is *** new species are:Cora accipiter Moncada,Madrin˜a´n&Lücking ***.,*** Moncada,Soto-Medina&Lücking ***.,*** Moncada,Dal Forno&Lücking ***.,*** Dal Forno,Chaves&Lücking ***.,*** Moncada,***ı´guez&Lücking ***.,*** Lücking,Moncada&*** ***.,*** Moncada,Ya´nez-Ayabaca&Lücking ***.,*** Moncada,Patin˜o&Lücking ***.,*** Lücking,***&Dal Forno ***.,*** Holgado,Rivas Plata&Perlmutter ***.,*** Dal Forno,Eliasaro&Spielmann ***.,*** Nugra,Dal Forno&Lücking ***.,*** Lücking,Martins&Lucheta ***.,*** Moncada,R.-***´rez&Lücking ***.,*** Moncada,***.&Lücking ***.,*** Moncada,CabreraAmaya&Lücking ***.,*** Moncada,R.-***´rez&***.,*** Lücking,***&Dal Forno ***.,*** Moncada,***´rez-Corredor&Lücking ***.,*** Moncada,***&Lücking ***.,***

关键词： Bolivia Citizen science Chile Mexico Puerto Rico Sri Lanka

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