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The Tower of Nisida as centre of 17^(th)century fortified naples system

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Frontiers of Architectural Research 2023年第2期12卷 308-318页

作者： Ignacio-javier Gil-Crespo Concetta Cusano Claudia Cennamo Research Center“Jose´Joaquı´n de Mora”/Ca´rdenas Foundation MadridSpain Dipartimento di Architettura e Disegno Industriale Universita`degli Studi della Campania“Luigi Vanvitelli”Aversa(CE)Italy

The paper investigates the territorial layout of the fortified system of Naples that developed during the Spanish Vice Kingdom in the 16th-17th *** existing castles and towers,and constructions built for the purpose,were included in the *** Tower of Nisida is one of the existing ancient towers that became part of the impressive 17th century defense system of *** study focus is on the strategic importance acquired by Nisida and its Tower in those years,when it became a key location in the fortified system,both evidencing its cruciality through the study of the field of vision that widens from the location and dealing the issue with the point of view landscape and territorial defense,recalling the concept that the defense architecture is part of architectural heritage.

关键词： Fortification Architectural heritage Territory and landscape Artillery Military architecture

Improving rice photosynthesis and yield through trehalose 6-phosphate signaling

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Molecular Plant 2022年第4期15卷 586-588页

作者： Matthew J.Paul javier A.Miret Cara A.Griffiths Plant Science Rothamsted ResearchAL52JQ HarpendenHertfordshireUK

THE T6P-SnRK1 SIGNALING PATHWAY IN PLANTS,The biosynthetic route for the synthesis of trehalose in plants is through a low-flux pathway that leads to the accumulation of micromolar amounts of trehalose 6-phosphate(T6P)and trehalose when sucrose is available.T6P accumulates in proportion to sucrose(Lunn et al.,2006)as an indispensable regulator of carbohydrate utilization(Schluepmann et al.,2003).At least some of the indispensability of T6P and its profound and widespread effects on plant growth and development can be explained through T6P inhibition of the SNF1-related protein kinase SnRK1(Zhang et al.,2009),a central regulator of plant responses to carbon and energy status.

关键词： molar synthesis explained

Corrigendum to“Moult intensity constraints along the complete moult sequence of the House Sparrow(Passer domesticus)”[Avian Res.14(2023)100125]

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Avian Research 2023年第4期14卷 716-717页

作者： Santi Guallar javier Quesada Departament de Vertebrats Museu de Ciències Naturals de BarcelonaBarcelona08003CataloniaSpain

In the original version of this article,we published a figure showing a gap in the confidence intervals for body and tail due to data paucity for mid stages of moult ***,we amended this problem adding data from the 2023 moulting season,during which we obtained 139 moult records from 98 *** final sample size used for plotting these results are shown in the caption *** amendment corroborates the conclusion already stated:body moult does not seem to be under physiological constraints,although primary moult appears to be tightly controlled to reduce aerodynamic losses.

关键词： constraints stated conclusion

Fungal diversity and community composition responses to the reintroduction of fire in a non-managed Mediterranean shrubland ecosystem

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Forest Ecosystems 2023年第2期10卷 268-278页

作者： Juncal Espinosa Tatek Dejene Mercedes Guijarro Xim Cerdá javier Madrigal Pablo Martín-Pinto Centre for the Research and Technology of Agro-Environmental and Biological Sciences University of Trás-os-Montes e Alto DouroVila RealPortugal Sustainable Forest Management Research Institute University of ValladolidPalenciaSpain Ethiopian Forestry Development Addis AbabaEthiopia Instituto de Ciencias Forestales(ICIFOR-INIA) CSICMadridSpain Estaciógica de Doñana CSICSevillaSpain University Polytechnic of Madrid ETSI MontesForestal y Medio NaturalMadridSpain

Background:More than a decade of fire suppression has changed the structure of fire-adapted shrubland ecosystems in Spain’s National Parks,which are now at extreme risk of uncontrolled *** burning can mitigate the risk of wildfires by reducing the fuel load but prescribed burning may also alter the soil properties and reduce microbial and fungal activity,causing changes in the availability of nutrients deep in the soil *** fungal communities are a vital part of post-fire restoration,some fire effects remain *** examine the short-term effects of prescribed burning on soil fungal communities in Doñana Biological Reserve(SW Spain),we collected soil samples pre-burn and 1 day,6 and 12 months post-burn from burned plots to perform physicochemical and metabarcode DNA ***:Prescribed burning had no significant effect on the total fungal operational taxonomic unit richness and ***,changes in soil pH,nitrogen and potassium content post-burn affected fungal community *** non-significant changes in pH and phosphorous affected the composition of ectomycorrhizal ***:The ectomycorrhizal fungal community appears to be resilient to the effects of low-to moderate-intensity fires and saprotrophic taxa may benefit from this kind of *** finding revealed that prescribed burning is a potentially valuable management tool for reducing fire hazards in shrublands that has little effect on the total richness and abundance of fungal communities.

关键词： Doñana National Park Ectomycorrhizal fungi Fire ecology Forest management Global change Prescribed burning Wildfire Saprotrophic fungi

Nature and evolution of the lower crust under central Spain:Inferences from granulite xenoliths(Calatrava Volcanic Field-Spanish central system)

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Geoscience Frontiers 2023年第3期14卷 10-32页

作者： David Orejana Carlos Villaseca Marlina A.Elburg Enrique Merino-Martínez javier García Serrano Departamento de Mineralogía y Petrología Universidad Complutense de MadridSpain Departamento de Dinámica Terrestre y Observación de la Tierra Instituto de Geociencias IGEO(UCMCSIC)MadridSpain Department of Geology University of JohannesburgSouth Africa Instituto Geológico y Minero de España–Consejo Superior de Investigaciones Científicas CN IGME–CSIC

So far,the nature and evolution of the lower crust under central Spain have been constrained mainly on the basis of a heterogeneous suite of granulite xenoliths from the Spanish Central System(SCS).In recent years,ultramafic volcanics from the Calatrava Volcanic Field(CVF)have also provided deep-seated crustal xenoliths which have not been studied in *** data,combining mineral,whole-rock and isotopic geochemistry with U–Pb–Hf isotope ratios in zircons from the CVF and SCS xenoliths,highlight the felsic composition of the lower crust under central Iberia.A number of the Calatrava xenoliths represents Variscan igneous protoliths,which are a minor population in the SCS,and were likely formed by crystallisation of intermediate and felsic melts in the lower crust during the Variscan orogeny(leucodiorite protolith age of 314±3 Ma and leucogranite protolith age of 308±2.5 Ma).U–Pb data of metamorphic zircons show that granulite-facies metamorphism mainly occurred from 299 to 285 Ma in both *** ages are slightly younger than those of granitic intrusions that could be genetically related to the granulitic residue,which points to a main role of U–Pb isotope resetting in lower crustal zircons during HT or UHT *** zircon U–Pb–Hf isotopic ratios support the idea that the lower crust in central Iberia consists mainly of Ordovician–Neoproterozoic metaigneous and metasedimentary rocks associated with the Cadomian continental arc of northern *** rocks provide evidence of mixing between juvenile magmas and an enriched crustal component,ultimately extracted from an Eburnean *** more evolved components present in detrital zircons are likely related to recycling of Archean crust derived from North Africa cratonic terranes.

关键词： Granulite xenoliths U-Pb geochronology Lu-Hf isotopes Calatrava Volcanic Field Spanish central system

Infrared phononic nanoantennas:Localized surface phonon polaritons in SiC disks

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Chinese Science Bulletin 2010年第24期55卷 2625-2628页

作者： AMEEN Mohamed garcia-ETXARRI Aitzol SCHNELL Martin HILLENBRAND Rainer AIZPURUA javier Department of Materials Physics University of the Basque Country UPV/EHU Centro Mixto de Física de Materiales CSIC-UPV/EHU and Donostia International Physics Centre Nanooptics Group CIC Nanogune Consolider Ikerbasque

The electromagnetic interaction of light with polar materials shows a sharp and well defined electromagnetic response in the infrared(IR)region that consists mainly of excitation of optical *** to surface plasmons in the visible region,surface phonons can couple efficiently to infrared light in micron-sized antennas made of polar *** applied the boundary element method to calculating the infrared electromagnetic response of single SiC disks acting as effective infrared antennas as a function of different parameters such as disk size and *** also analyzed the effect of locating a probing metallic tip near the SiC disk to scatter light in the proximity of the SiC disk,thereby obtaining new spectral peaks connected with localized modes between the tip and the SiC *** then further investigated their application in IR scanning probe microscopy.A near-field map of the phononic resonances enhances the understanding of the nature of the IR extinction peaks.

关键词：表面声子碳化硅光磁盘红外线极化激元扫描探针显微技术电磁相互作用电磁响应

The short form of the SUR1 and its functional implications in the damaged brain

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Neural Regeneration Research 2022年第3期17卷 488-496页

作者： Iván Alquisiras-Burgos javier Franco-Pérez Moisés Rubio-Osornio Penélope Aguilera Laboratorio de Patología Vascular Cerebral Instituto Nacional de Neurología y Neurocirugía“Manuel Velasco Suárez”CDMXMexico Laboratorio de Formación Reticular Instituto Nacional de Neurología y Neurocirugía“Manuel Velasco Suárez”CDMXMexico Laboratorio Experimental de Enfermedades Neurodegenerativas Instituto Nacional de Neurología y Neurocirugía“Manuel Velasco Suárez”CDMXMexico.

Sulfonylurea receptor(SUR) belongs to the adenosine 5′-triphosphate(ATP)-binding cassette(ABC) transporter family;however,SUR is associated with ion channels and acts as a regulatory subunit determining the opening or closing of the ***8 and Abcc9 genes code for the proteins SUR1 and SUR2,*** SUR1 transcript encodes a protein of 1582 amino acids with a mass around 140–177 k Da expressed in the pancreas,brain,heart,and other *** is well known that SUR1 assembles with Kir6.2 and TRPM4 to establish K_(ATP) channels and non-selective cation channels,***8 and 9 are alternatively spliced,and the resulting transcripts encode different isoforms of SUR1 and SUR2,which have been detected by different experimental ***,the use of binding assays to sulfonylureas and Western blotting has allowed the detection of shorter forms of SUR(-65 k Da).Identity of the SUR1 variants has not been clarified,and some authors have suggested that the shorter forms are ***,immunoprecipitation assays have shown that SUR2 short forms are part of a functional channel even coexisting with the typical forms of the receptor in the *** evidence confirms that the structure of the short forms of the SURs is fully functional and does not lose the ability to interact with the *** structural changes in short forms of SUR modify its affinity to ATP,regulation of its expression might represent an advantage in pathologies where ATP concentrations decrease and a therapeutic target to induce ***,the expression of SUR1 variants might be induced by conditions associated to the decrease of energetic substrates in the brain(*** stroke and epilepsy).In this review,we want to contribute to the knowledge of SUR1 complexity by analyzing evidence that shows the existence of short SUR1 variants and its possible implications in brain function.

关键词： brain edema epilepsy Parkinson's disease stroke sulfonylurea receptor 1 SUR1 traumatic brain injury TRPM4

1D alignment of proteins and other nanoparticles by using reversible covalent bonds on cyclic peptide nanotubes

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Organic Chemistry Frontiers 2022年第5期9卷 1226-1233页

作者： Juan M.Priegue Iria Louzao Ivan Gallego javier Montenegro Juan R.Granja Singular Research Centre in Chemical Biology and Molecular Materials (CIQUS)Organic Chemistry DepartmentUniversity of Santiago de Compostela(USC)15782 Santiago de CompostelaSpain

Self-assembling cyclic peptide nanotubes are supramolecular structures whose diameter and external surface properties are precisely *** this communication we describe a general strategy to align different molecules on... 详细信息

关键词： nanoparticles alignment surface

Protein-protein interface analysis of the non-ribosomal peptide synthetase peptidyl carrier protein and enzymatic domains

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Synthetic and Systems Biotechnology 2022年第2期7卷 671-682页

作者： Joshua C.Corpuz javier O.Sanlley Michael D.Burkart Department of Chemistry and Biochemistry University of California-San Diego9500 Gilman DriveLa JollaCA92093-0358USA

Non-ribosomal peptide synthetases(NRPSs)are attractive targets for biosynthetic pathway engineering due to their modular architecture and the therapeutic relevance of their *** catalysis mediated by specific protein-protein interactions formed between the peptidyl carrier protein(PCP)and its partner enzymes,NRPS enzymology and control remains fertile ground for *** review focuses on the recent efforts within structural biology by compiling high-resolution structural data that shed light into the various protein-protein interfaces formed between the PCP and its partner enzymes,including the phosphopantetheinyl transferase(PPTase),adenylation(A)domain,condensation(C)domain,thioesterase(TE)domain and other tailoring enzymes within the *** our understanding of how the PCP recognizes partner proteins with the potential to use directed evolution and combinatorial biosynthetic methods will enhance future efforts in discovery and production of new bioactive compounds.

关键词： Natural products Protein-protein interactions Non-ribosomal peptide synthetase Peptidyl carrier protein Combinatorial biosynthesis Synthetic biology