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Environmental geochemistry studies and health risk assessment to identify priority areas for remediation of polluted soils in the Santa Maria de la Paz (S.L.P., Mexico) mining district

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Chinese Journal Of Geochemistry 2006年第B8期25卷 61-61页

作者： Israel Razo Fernando Diaz-Barriga javier castro Marcos Monroy Universidad Autonoma de San Luis Potosi/Instituto de Metalurgia/San Luis Potosi S.L.P. (Mexico)

全有机多功能组成物用于冷却塔含高浓度总硬储水的水处理

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水处理信息报导 2008年第5期 37-37页

作者： Ruvira, Sergio javier castro

本发明提供了一种全有机水溶性组成物，其能够提高具有高含量总硬的冷却塔水化学处理的功效，该总硬度主要由钙组成，特别用于石化行业的冷却塔水处理，并且在高浓缩倍数下运行，能够充分控制热交换设备中腐蚀、结垢和分散问题，避免工... 详细信息

本发明提供了一种全有机水溶性组成物，其能够提高具有高含量总硬的冷却塔水化学处理的功效，该总硬度主要由钙组成，特别用于石化行业的冷却塔水处理，并且在高浓缩倍数下运行，能够充分控制热交换设备中腐蚀、结垢和分散问题，避免工艺设备污染趋势，以及控制细菌繁殖。当在具有重金属的冷却系统中使用该配方，该组成物还可以去除重金属，如锌，通过使用本发明，可以避免排出污染物，原因是该组成物是一种多功能产品，其化学组成是全有机且能够被生物降解。

关键词：多功能产品组成物冷却塔水处理储水浓度水化学处理高浓缩倍数

半有机多功能组成物用于冷却塔中含有低浓度钙和高温稳定性的水的处理

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水处理信息报导 2008年第5期 36-36页

作者： Ruvira, Sergio javier castro

本发明提供了一种水溶性组成物，名叫IMP-TE-511，其能够提高高浓缩倍数下的石化设备储水中含有低浓度钙和高度稳定的冷却水化学处理的功效，为工艺设备提供充分的腐蚀、结垢和分散控制，特别是在乙烯、聚丙烯、乙醛、氧、丙烯腈设备和... 详细信息

本发明提供了一种水溶性组成物，名叫IMP-TE-511，其能够提高高浓缩倍数下的石化设备储水中含有低浓度钙和高度稳定的冷却水化学处理的功效，为工艺设备提供充分的腐蚀、结垢和分散控制，特别是在乙烯、聚丙烯、乙醛、氧、丙烯腈设备和辅助设备中。

关键词：高温稳定性低浓度组成物水溶性冷却塔多功能冷却水化学处理钙

Hepatobiliary manifestations in inflammatory bowel disease: The gut,the drugs and the liver

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World Journal of Gastroenterology 2013年第42期19卷 7327-7340页

作者： María Rojas-Feria Manuel castro Emilio Suárez javier Ampuero Manuel Romero-Gómez Unit for Medical and Surgical Management of Digestive Diseases and CIBERehd Valme University HospitalUniversity of SevilleE-41014 SevillaSpain

Abnormal liver biochemical tests are present in up to30%of patients with inflammatory bowel disease(IBD),and therefore become a diagnostic *** and biliary tract diseases are common extraintestinal manifestations for both Crohn’s disease and ulcerative colitis(UC),and typically do not correlate with intestinal *** sclerosing cholangitis(PSC)is the most common hepatobiliary manifestation of IBD,and is more prevalent in *** 5%of patients with UC develop PSC,with the prevalence reaching up to 90%.Cholangiocarcinoma and colon cancer risks are increased in these *** common disorders include autoimmune hepatitis/PSC overlap syndrome,IgG4-associated cholangiopathy,primary biliary cirrhosis,hepatic amyloidosis,granulomatous hepatitis,cholelithiasis,portal vein thrombosis,liver abscess,and non-alcoholic fatty liver *** B reactivation during immunosuppressive therapy is a major concern,with screening and vaccination being recommended in serologically negative cases for patients with *** prophylaxis with entecavir or tenofovir for 6to 12 mo after the end of immunosuppressive therapy is mandatory in patients showing as hepatitis B surface antigen(HBsAg)positive,independently from viral *** negative and anti-HBc positive patients,with or without anti-HBs,should be closely monitored,measuring alanine aminotransferase and hepatitis B virus DNA within 12 mo after the end of therapy,and should be treated if the viral load *** the other hand,immunosuppressive therapy does not seem to promote reactivation of hepatitis C,and hepatitis C antiviral treatment does not influence IBD natural history *** of the drugs used for IBD treatment may induce hepatotoxicity,although the incidence of serious adverse events is *** in liver biochemical tests associated with aminosalicylates are uncommon and are usually not clinically *** hepatotoxicity has been describ

关键词： Inflammatory bowel disease Hepatobiliary disorders Extraintestinal manifestations Primary sclerosing cholangitis Drug-induced liver injury Hepatotoxicity Hepatitis B Hepatitis C

From conventional two-stage hepatectomy to ALPPS:Fifteen years of experience in a hepatobiliary surgery unit

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Hepatobiliary & Pancreatic Diseases International 2021年第6期20卷 542-550页

作者： javier Maupoey Ibáñez Eva María MontalváOrón Andrea BoscàRobledo Alonso Camacho Ramírez Ana Hernando Sanz Pablo Granero castro Alberto Alegre Delgado Rafael López-Andújar Hepatobiliary Surgery and Transplant Unit La Fe University and Polytechnic HospitalValenciaSpain Department of Radiology La Fe University and Polytechnic HospitalValenciaSpain

Background:Hepatectomy in patients with large tumor load may result in postoperative liver failure and associated complications due to excessive liver parenchyma *** two-stage hepatectomy(TSH)and associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)technique are possible solutions to this *** liver metastases(CRLM)is the most frequent indication,and there is a need to assess outcomes for both techniques to improve surgical and long-term oncological outcomes in these ***:A single-center retrospective study was designed to compare TSH with ALPPS in patients with initially unresectable bilateral liver tumors between January 2005 and January *** was performed from January 2012 onwards as the technique of ***-term overall survival(OS)and disease-free survival(DFS)were evaluated as primary outcome in CRLM *** morbidity,mortality and liver growth in all patients were also ***:A total of 38 staged hepatectomies were performed:17 TSH and 21 *** resection rate was 76.5%(n=13)in the TSH group and 85.7%(n=18)in the ALPPS group(P=0.426).Overall major morbidity(Clavien-Dindo≥3 a)(stage 1+stage 2)was 41.2%(n=7)in TSH and 33.3%(n=7)in ALPPS patients(P=0.389),and perioperative 90-day mortalities were 11.8%(n=2)vs.19.0%(n=4)in each group,respectively(P=0.654).Intention-to-treat OS rates at 1 and 5 years in CRLM patients for TSH(n=15)were 80%and 33%,and for ALPPS(n=17)76%and 35%,*** rates at 1 and 5 years were 36%and 27%in the TSH group vs.33%and 27%in the ALPPS group,***:ALPPS is an effective alternative to TSH in bilateral affecting liver tumors,allowing higher resection rate,but patients must be carefully *** CRLM patients similar long-term OS and DFS can be achieved with both techniques.

关键词： ALPPS Two-stage hepatectomy Colorectal liver metastases Posthepatectomy liver failure

Paracentral acute middle maculopathy after diagnostic cerebral angiography in a patient with a contralateral carotid-cavernous fistula

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International Journal of Ophthalmology(English edition) 2022年第11期15卷 1888-1890页

作者： Lidia Remoli Sargues javier Montero Hernández Clara Monferrer Adsuara Nuria Gonzalez Giron Alicia Gracia Garcia Veronica castro Navarro Enrique Cervera Taulet Department of Ophthalmology Consorcio Hospital General Universitario of ValenciaAv.Tres Cruces 2Valencia 46014Spain

Dear Editor, I am Dr. Lidia Remolí Sargues from Consorcio Hospital General Universitario of Valencia. We write to present a case of paracentral acute middle maculopathy(PAMM) in a patient with a contralateral carotid... 详细信息

关键词： cerebral fistula acute

Mediation role of cardiorespiratory fitness on the association between fatness and cardiometabolic risk in European adolescents: The HELENA study

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Journal of Sport and Health Science 2021年第3期10卷 360-367页

作者： Carlos Cristi-Montero javier Courel-Ibanez Francisco B.Ortega Jose castro-Pinero Alba Santaliestra-Pasias Angela Polito Jeremy Vanhelst Ascension Marcos Luis M.Moreno Jonatan R.Ruiz IRyS Group Physical Education SchoolPontificia Universidad Catolicade ValparaisoValparaisso 2530388Chile Department of Physical Activity and Sport Faculty of Sport SciencesUniversity of MurciaMurcia 30071Spain PROmoting FITness and Health through Physical Activity Research Group(PROFITH) Department of Physical Education and SportsFaculty of Sport SciencesUniversity of GranadaGranada 18001Spain Department of Physical Education Faculty of Education SciencesUniversity of CadizPuerto Real 11003Spain Department of Health and Human Performance School of Health SciencesUniversity of ZaragozaZaragoza 50001Spain Growth ExerciseNutrition and Development(GENUD)Research GroupZaragoza 50001Spain National Institute for Food and Nutrition Research Rome 80070Italy Lille Inflammation Research International Center University of LilleLille 59000France Immunonutrition Research Group Department Metabolism and NutritionInstitute of Food Science and Technology and Nutrition(ICTAN)Spanish National Research Council(CSIC)Madrid E-28040 Spain

Purpose:This study was aimed to analyze the mediation role of cardiorespiratory fitness(CRF)on the association between fatness and cardiometabolic risk scores(CMRs)in European ***:A cross-sectional study was conducted in adolescents(n=525;46%boys;14.1±1.1 years old,mean ±SD)from 10 European cities involved in the Healthy Lifestyle in Europe by Nutrition in Adolescence *** was measured by means of the shuttle run test,while fatness measures included body mass index(BMI),waist to height ratio,and fat mass index estimated from skinfold thicknesses.A clustered CMRs was computed by summing the standardized values of homeostasis model assessment,systolic blood pressure,triglycerides,total cholesterol/highdensity lipoprotein cholesterol ratio,and ***:Linear regression models indicated that CRF acted as an important and partial mediator in the association between fatness and CMRs in 1217-year-old adolescents(for BMI:coefficients of the indirect role b=0.058(95%confidence interval(95%CI):0.023-0.101),Sobel test z=3.11(10.0%mediation);for waist to height ratio:b=4.279(95%CI:2.242-7.059),z=3.86(11.5%mediation);and for fat mass index:b=0.060(95%CI:0.020-0.106),z=2.85(9.4%mediation);all p<0.01).Conclusion:In adolescents,the association between fatness and CMRs could be partially decreased with improvements to fitness levels;therefore,CRF contribution both in the clinical field and public health could be important to consider and promote in adolescents independently of their fatness levels.

关键词： Cardiovascular disease Children Fat mass Fitness Health Physical activity

Ubiquitous Computing and Its Applications in the Disease Management in a Ubiquitous City

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Journal of Computer and Communications 2018年第3期6卷 19-42页

作者： javier Cabo Salvador Jose Miguel Ramirez Uceda Veronica Cabo Muinos javier Ramos Lopez Carlos de castro Cátedra de Telemedicina Universidad Internacional de AndalucíaSevilleSpain CITEC Centro de Investigaciones Tecnológicas Universidad de CórdobaCórdobaSpain Cátedra de Gestión Sanitaria y Ciencias de la Salud UDIMAMadridSpain IHM-Medical Technology MadridSpain Fundación de Ingeniería Biomédica MadridSpain Escuela Técnica Superior de Ingenieros de Telecomunicación Universidad Rey Juan CarlosMadridSpain Departamento Cardiovascular Hospital Vithas NISA Pardo de Aravaca MadridSpain

The actual challenge in health is to manage patients with chronic diseases from a holistic approach where technology around the patient and at the city enhances their wellness. This paper deepens in the relations between health, devices, and models of technological cities and how these can be modeled to provide a more cost efficient solution while less invasive and more natural to the end users. In light of this, usable and accessible software and a wide range of devices, ranging from PC, smartphone, tablet and SmartTV have been tested. This manuscript will give good comprehension on how technology and disease management care models interact with the patient.

关键词： U-Health Ubiquitous Computing Internet of Things Spimes

Promising diagnostic biomarkers of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: From clinical proteomics to microbiome

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World Journal of Hepatology 2021年第11期13卷 1494-1511页

作者： Carolina Castillo-castro Alexandro JoséMartagón-Rosado Rocio Ortiz-Lopez Luis Felipe Garrido-Treviño Melissa Villegas-Albo Francisco javier Bosques-Padilla Tecnológico de Monterrey Escuela de Medicina y Ciencias de la SaludMonterrey 64710Mexico Unidad de Investigación de Enfermedades Metabólicas Instituto Nacional de Ciencias Médicas y NutriciónCiudad de México 14080Mexico Centro Regional para el Estudio de las Enfermedades Digestivas Servicio de GastroenterologíaFacultad de Medicina y Hospital Universitario Dr.JoséEleuterio GonzálezUniversidad Autónoma de Nuevo LeónMonterrey 64460Mexico

Fatty liver has been present in the lives of patients and physicians for almost two *** knowledge has been generated regarding its etiology and consequences,although a long path seeking novel and innovative diagnostic biomarkers for nonalcoholic fatty liver disease(NAFLD)and nonalcoholic steatohepatitis(NASH)is still *** the one hand,proteomics and lipidomics have emerged as potential noninvasive resources for NAFLD *** contrast,metabolomics has been able to distinguish between NAFLD and NASH,even detecting degrees of *** the other hand,genetic and epigenetic markers have been useful in monitoring disease progression,eventually functioning as target *** markers involved in immune dysregulation,oxidative stress,and inflammation are involved in the instauration and evolution of the ***,the fascinating gut microbiome is significantly involved in NAFLD and *** review presents state-of-the-art biomarkers related to NAFLD and NASH and new promises that could eventually be positioned as diagnostic resources for this *** is evident,despite great advances in studying these biomarkers,there is still a long path before they translate into clinical benefits.

关键词： Fatty liver Biomarkers Nonalcoholic fatty liver disease Nonalcoholic steatohepatitis