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High-frequency enhanced ultrafast compressed active photography

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Opto-Electronic Advances 2025年第1期8卷 32-43页

作者： yizhao Meng Yu lu Pengfei Zhang yi Liu Fei yin lin Kai Qing Yang Feng chen State Key Laboratory for Manufacturing System Engineering and Shaanxi Key Laboratory of Photonics Technology for Information School of Electronic Science and EngineeringXi’an Jiaotong UniversityXi’an 710049China School of Mechanical Engineering Xi’an Jiaotong UniversityXi’an 710049China

Single-shot ultrafast compressed imaging(UCI)is an effective tool for studying ultrafast dynamics in physics,chemistry,or material science because of its excellent high frame rate and large frame ***,the random code(Rcode)used in traditional UCI will lead to low-frequency noise covering high-frequency information due to its uneven sampling interval,which is a great challenge in the fidelity of large-frame ***,a high-frequency enhanced compressed active photography(H-CAP)is *** uniformizing the sampling interval of R-code,H-CAP capture the ultrafast process with a random uniform sampling *** sampling mode makes the high-frequency sampling energy dominant,which greatly suppresses the low-frequency noise blurring caused by R-code and achieves high-frequency information of image *** superior dynamic performance and large-frame reconstruction ability of H-CAP are verified by imaging optical self-focusing effect and static object,*** applied H-CAP to the spatial-temporal characterization of double-pulse induced silicon surface ablation dynamics,which is performed within 220 frames in a single-shot of 300 ps.H-CAP provides a high-fidelity imaging method for observing ultrafast unrepeatable dynamic processes with large frames.

关键词： ultrafast compressed imaging high-frequency enhanced sampling spectral-temporal transform transient processes high-fidelity reconstruction

Is intraperitoneal isoperistaltic side-to-side anastomosis a safe surgical procedure in radical colon cancer surgery

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World Journal of Gastrointestinal Oncology 2025年第3期17卷 133-143页

作者： Bin Wu jing-Tao Zhu He-Xin lin Yu-Hua Dai Tian-Sheng lin An-Le Huang yi-Nan chen Yong-Wen Li Hai-Bin Wang yi-Fu chen Dong-Han chen Huang-Dao Yu Jun You Qing-Qi Hong Department of Gastrointestinal Oncology Surgery The First Affiliated Hospital of Xiamen UniversitySchool of MedicineXiamen UniversityXiamen 361003Fujian ProvinceChina

BACKGROUND Colorectal cancer,one of the most common malignancies,is primarily treated through *** the widespread use of laparoscopy,gastrointestinal reconstruction remains a key area of *** choice between intraperitoneal anastomosis(IA)and extraperitoneal anastomosis(EA)remains a subject of considerable *** study uses intraperitoneal isoperistaltic side-to-side anastomosis(IISSA)with hand-sewn closure of the common opening to evaluate its safety and short-term *** is hypothesized that this technique may offer better short-term outcomes than *** To investigate the safety and short-term outcomes of IISSA with hand-sewn closure of the common opening compared to *** Patients who underwent laparoscopic radical colon cancer surgery between January 2018 and June 2022 at the First Affiliated Hospital of Xiamen University were retrospectively ***,postoperative,and pathological features of the IA and EA groups were observed before and after propensity score *** with right-sided and left-sided colon cancer were separated,each further divided into IA and EA groups(R-IA vs R-EA for right-sided,L-IA vs L-EA for left-sided),for stratified analysis of the aforementioned *** After propensity score matching,63 pairs were matched in each *** surgical characteristics,the IA group exhibited less blood loss and shorter incisions than the EA *** postoperative recovery,the IA group showed earlier recovery of gastrointestinal ***,the IA group had greater lymph node *** to the R-EA group,the R-IA group experienced reduced blood loss,shorter assisted incisions,earlier recovery of gastrointestinal functions and greater lymph node *** compared to the L-EA group,the L-IA group demonstrated earlier postoperative anal exhaust and defecation,along with a reduced length of *** postoperative complications,no statistically signific

关键词： Colon cancer Laparoscopic surgery Intraperitoneal anastomosis Extraperitoneal anastomosis Isoperistaltic sideto-side anastomosis Hand-sewn

Cross-sectional study of the association between triglyceride glucose-body mass index and obstructive sleep apnea risk

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World Journal of Diabetes 2025年第3期16卷 65-75页

作者： Li Gong Ming Su jing-Han Xu Zhen-Fei Peng lin Du Ze-Yao chen Yu-Zhou Liu lu-Cia Chan yin-luan Huang Yu-Tian chen Feng-yi Huang chun-Li Piao Department of Diabetes Shenzhen Bao'an Chinese Medicine Hospital Guangzhou University of Chinese MedicineShenzhen 518100Guangdong ProvinceChina Department of Pneumology Shenzhen Bao'an Chinese Medicine Hospital Guangzhou University of Chinese MedicineShenzhen 518100Guangdong ProvinceChina Department of Endocrinology Shenzhen Hospital(Futian)of Guangzhou University of Chinese MedicineShenzhen 518100Guangdong ProvinceChina

BACKGROUND The triglyceride glucose-body mass index(TyG-BMI)is a novel indicator of insulin resistance(IR).Obstructive sleep apnea(OSA)is a prevalent disorder characterized by recurrent complete or partial collapse of the pharyngeal airway during sleep;however,the relationship between these two conditions remains *** hypothesized that a higher TyG-BMI is associated with the occurrence of *** To assess the association between TyG-BMI and OSA in adults in the United *** A cross-sectional study was conducted utilizing data from the National Health and Nutrition Examination Surveys spanning from 2005-2008 to *** was calculated as Ln[triglyceride(mg/dL)×fasting blood glucose(mg/dL)/2]×*** cubic splines were used to analyze the risk of TyG-BMI and OSA *** identify potential nonlinear relationships,we combined Cox proportional hazard regression with smooth curve *** also conducted sensitivity and subgroup analyses to verify the robustness of our *** We included 16794 participants in the final *** regression analysis showed that participants with a higher TyG-BMI had a higher OSA *** adjusting for all covariates,TyG-BMI was positively correlated with the prevalence of OSA(odds ratio:1.28;95%confidence interval:1.17,1.40;Plinear relationship was *** analysis showed no strong correlation between TyG-BMI and OSA in patients with *** correlation between TyG-BMI and OSA was influenced by age,sex,smoking status,marital status,hypertensive stratification,and obesity;these subgroups played a moderating role between TyGBMI and *** after adjusting for all covariates,there was a positive association between TYG-BMI and OSA *** A higher TyG-BMI index is linked to higher chances of developing *** TyG-BMI is an indicator of IR,managing IR may help reduce the risk of OSA.

关键词： Obstructive sleep apnea Triglyceride glucose-body mass index Insulin resistance Cross-sectional National Health and Nutrition Examination Surveys

Activation of zona incerta gamma-aminobutyric acid-ergic neurons alleviates depression-like and anxiety-like behaviors induced by chronic restraint stress

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World Journal of Psychiatry 2025年第2期15卷 209-221页

作者： Si-Hai chen Bo Lan ying-ying Zhang Guo-Hui Li Yu-Long Qian Ming-Xing Hu yin-lin Tian Wei-Dong Zang jing Cao Guang-Hai Wang yi-Gang Wang Department of Psychiatry Xiaogan Rehabilitation HospitalXiaogan 432000Hubei ProvinceChina School of Basic Medical Sciences Zhengzhou UniversityZhengzhou 450000Henan ProvinceChina School of Nursing and Health Zhengzhou UniversityZhengzhou 450000Henan ProvinceChina

BACKGROUND Depression is a prevalent affective disorder,but its pathophysiology remains *** in the gamma-aminobutyric acid(GABA)-ergic system may contribute to its ***,antidepressants(e.g.,brexanolone,zuranolone)targeting the GABA-A receptor were *** zona incerta(ZI),an inhibitory subthalamic region mainly composed of GABAergic neurons,has been implicated in emotional *** brain stimulation of the ZI in humans affects anxiety and depression symptoms,while activation of ZI neurons in mice can either worsen or alleviate ***,there is no direct evidence linking GABAergic neurons in the ZI to depression-like behaviors in *** To explore the relationship between GABAergic neurons in the ZI and depression-like behaviors in *** A chronic restraint stress(CRS)model was utilized to induce depression in ***-cell patch-clamp recordings assessed the excitability changes of GABAergic neurons in the ***,chemogenetic techniques were employed to modulate ZI GABAergic *** performance of the mice in behavioral tests for depression and anxiety was *** The findings indicated that GABAergic neurons in the ZI were closely associated with depression-like behaviors in ***-eight days after the CRS model was established,depression-like and anxiety-like behaviors were observed in the *** excitability of GABAergic neurons in the ZI was *** activation of these neurons alleviated CRS-induced depression-like and anxiety-like ***,inhibition of GABAergic neurons in the ZI led to changes in emotion-related behavioral outcomes in *** Activity of GABAergic neurons in the ZI was closely associated with depression-like phenotypes in mice,suggesting that these neurons could be a potential therapeutic target for treating depression.

关键词： Zona incerta Gamma-aminobutyric acid-ergic Depression Anxiety Animal behavior studies Whole-cell patchclamp

Predictive value of a constructed artificial neural network model for microvascular invasion in hepatocellular carcinoma:A retrospective study

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 88-100页

作者： Hai-Yang Nong Yong-yi Cen Shan-Jin lu Rui-Sui Huang Qiong chen Li-Feng Huang Jian-Ning Huang Xue Wei Man-Rong Liu lin Li Ke Ding Department of Radiology The Third Affiliated Hospital of Guangxi Medical UniversityNanning 530031Guangxi Zhuang Autonomous RegionChina Department of Radiology Affiliated Hospital of Youjiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Guangxi Clinical Medical Research Center for Hepatobiliary Diseases Affiliated Hospital of Youiiang Medical University for NationalitiesBaise 533000Guangxi Zhuang Autonomous RegionChina Department of Ultrasound The Third Affiliated Hospital of Guangxi Medical UniversityNanning 530031Guangxi Zhuang Autonomous RegionChina Department of Hepatobiliary Surgery The Third Affiliated Hospital of Guangxi Medical UniversityNanning 530031Guangxi Zhuang Autonomous RegionChina

BACKGROUND Microvascular invasion(MVI)is a significant risk factor for recurrence and metastasis following hepatocellular carcinoma(HCC)***,there is a paucity of preoperative evaluation approaches for *** To investigate the predictive value of texture features and radiological signs based on multiparametric magnetic resonance imaging in the non-invasive preoperative prediction of MVI in *** Clinical data from 97 HCC patients were retrospectively collected from January 2019 to July 2022 at our *** were classified into two groups:MVI-positive(n=57)and MVI-negative(n=40),based on postoperative pathological *** correlation between relevant radiological signs and MVI status was ***4.6 software and the mutual information method were employed to identify the top 10 dominant texture features,which were combined with radiological signs to construct artificial neural network(ANN)models for MVI *** predictive performance of the ANN models was evaluated using area under the curve,sensitivity,and *** models with relatively high predictive performance were screened using the DeLong test,and the regression model of multilayer feedforward ANN with backpropagation and error backpropagation learning method was used to evaluate the models’*** The absence of a pseudocapsule,an incomplete pseudocapsule,and the presence of tumor blood vessels were identified as independent predictors of HCC *** ANN model constructed using the dominant features of the combined group(pseudocapsule status+tumor blood vessels+arterial phase+venous phase)demonstrated the best predictive performance for MVI status and was found to be automated,highly operable,and very *** The ANN model constructed using the dominant features of the combined group can be recommended as a noninvasive method for preoperative prediction of HCC MVI status.

关键词： Hepatocellular carcinoma Texture analysis Magnetic resonance imaging Microvascular invasion Pseudocapsule Tumor blood vessels

Mitochondrial mt12361A>G increased risk of metabolic dysfunctionassociated steatotic liver disease among non-diabetes

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World Journal of Gastroenterology 2025年第10期31卷 38-50页

作者： Ming-ying lu Yu-Ju Wei Chih-Wen Wang Po-cheng Liang Ming-lun Yeh yi-Shan Tsai pei-Chien Tsai Yu-Min Ko ching-Chih lin Kuan-Yu chen yi-Hung lin Tyng-Yuan Jang Ming-Yen Hsieh Zu-Yau lin chung-Feng Huang Jee-Fu Huang Chia-Yen Dai Wan-Long Chuang Ming-lung Yu Hepatitis Center and Hepatobiliary Division Department of Internal MedicineKaohsiung Medical University HospitalKaohsiung 80708Taiwan School of Medicine and Doctoral Program of Clinical and Experimental Medicine College of Medicine and Center of Excellence for Metabolic Associated Fatty Liver DiseaseNational Sun Yat-sen UniversityKaohsiung 80708Taiwan

BACKGROUND Insulin resistance,lipotoxicity,and mitochondrial dysfunction contribute to the pathogenesis of metabolic dysfunction-associated steatotic liver disease(MASLD).Mitochondrial dysfunction impairs oxidative phosphorylation and increases reactive oxygen species production,leading to steatohepatitis and hepatic *** intelligence(AI)is a potent tool for disease diagnosis and risk *** To investigate mitochondrial DNA polymorphisms in susceptibility to MASLD and establish an AI model for MASLD *** Multiplex polymerase chain reaction was performed to comprehensively genotype 82 mitochondrial DNA variants in the screening dataset(n=264).The significant mitochondrial single nucleotide polymorphism was validated in an independent cohort(n=1046)using the Taqman®allelic discrimination *** forest,eXtreme gradient boosting,Naive Bayes,and logistic regression algorithms were employed to construct an AI model for *** In the screening dataset,only mt12361A>G was significantly associated with ***12361A>G showed borderline significance in MASLD patients with 2-3 cardiometabolic traits compared with controls in the validation dataset(P=0.055).Multivariate regression analysis confirmed that mt12361A>G was an independent risk factor of MASLD[odds ratio(OR)=2.54,95%confidence interval(CI):1.19-5.43,P=0.016].The genetic effect of mt12361A>G was significant in the non-diabetic group but not in the diabetic ***12361G carriers had a 2.8-fold higher risk than A carriers in the non-diabetic group(OR=2.80,95%CI:1.22-6.41,P=0.015).By integrating clinical features and mt12361A>G,random forest outperformed other algorithms in detecting MASLD[training area under the receiver operating characteristic curve(AUROC)=1.000,validation AUROC=0.876].CONCluSION The mt12361A>G variant increased the severity of MASLD in non-diabetic *** supports the screening and management of MASLD in primary care settings.

关键词： Metabolic dysfunction-associated steatotic liver disease Mitochondrial DNA Artificial intelligence Machine learning Algorithm

Shortening the recipient warm ischemia time could be a strategy for expanding the liver donor pool

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World Journal of Gastroenterology 2025年第9期31卷 135-145页

作者： Jia-Wei Yu lin-Biao Xiang Xiao-Juan Dong chen-Xi Yang Lei Wang Xiao-Yu Liu yi-Hong Song Xian-Jie Bai jing-Wen Xiao lu Ren Qin-Hong Xu Gang-Hua Yang yi Lv Qiang lu National Local Joint Engineering Research Center for Precision Surgery and Regenerative Medicine The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of International Medical Center The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina Department of Geriatric Surgery The First Affiliated Hospital of Xi'an Jiaotong UniversityXi’an 710061Shaanxi ProvinceChina

BACKGROUND Shortening the recipient warm ischemia time(rWIT)has been proven to be effective for improving the short-and long-term outcomes after liver transplantation(LT)and offsets the negative impact of an extended cold ischemia ***,few studies have been conducted to explore the prognostic effects of shortening the rWIT in transplantations using a liver graft from an extendedcriteria donor(ECD).AIM To investigate whether shortening the rWIT could improve the outcomes of ECD *** Rat ECD autologous orthotopic LT were performed with variable rWITs(0,10,20,and 30 minutes).Near-infrared fluorescence imaging(FI)was used for the real-time assessment of liver graft ischemia-reperfusion injury after the anhepatic *** was assessed,and liver function and histological analyses were performed on the third day after *** The FI curve growth rate and postoperative three-day survival rate significantly increased,and the liver function and Suzuki score of the liver grafts significantly improved when the rWIT was≤10 minutes(PluSION The post-transplant outcomes were significantly better with a shorter rWIT(10 minutes or less)than with a longer rWIT,which could be a strategy for expanding the liver donor pool.

关键词： Extended criteria donor Recipient warm ischemia time Autologous orthotopic liver transplantation Near-infrared fluorescence imaging Outcome

The GECAM ground search system for gamma-ray transients

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Science China(Physics,Mechanics & Astronomy) 2025年第3期68卷 161-174页

作者： Ce Cai Yan-Qiu Zhang Shao-lin Xiong Ping Wang Jian-Hui Li Xiao-Bo Li cheng-Kui Li Yue Huang Shi-Jie Zheng Li-Ming Song Shuo Xiao Qi-Bin yi yi Zhao Sheng-lun Xie Rui Qiao Yan-Qi Du Zhi-Wei Guo Wang-chen Xue Chao Zheng Jia-Cong Liu chen-Wei Wang Wen-Jun Tan Yue Wang Jin-Peng Zhang Chao-Yang Li Guo-ying Zhao Xiao-Yun Zhao Xiao-lu Zhang Zhen Zhang Wen-Xi Peng Xiang Ma jing-Yan Shi Dong-Ya Guo Jin Wang Xin-Qiao Li Xiang-Yang Wen Zheng-Hua An Fan Zhang College of Physics and Hebei Key Laboratory of Photophysics Research and Application Hebei Normal UniversityShijiazhuang050024China Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing100049China University of Chinese Academy of Sciences Beijing100049China School of Physics and Electronic Science Guizhou Normal UniversityGuiyang550001China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guizhou Normal UniversityGuiyang550001China School of Physics and Optoelectronics Xiangtan UniversityXiangtan411105China School of Computer and Information Dezhou UniversityDezhou253023China Institute of Astrophysics Central China Normal UniversityWuhan430079China

In the era of time-domain,multi-messenger astronomy,the detection of transient events on the high-energy electromagnetic sky has become more important than *** gravitational wave high-energy electromagnetic counterpart all-sky monitor(GECAM)is a dedicated mission to monitor gamma-ray transients,launched in December,2020.A real-time on-board trigger and location software,using the traditional signal-to-noise ratio(SNR)method for blind search,is constrained to relatively bright signals due to the limitations in on-board computing resources and the need for real-time *** this work,we developed a ground-based pipeline for GECAM to search for various transients,especially for weak bursts missed by on-board *** pipeline includes both automatic and manual mode,offering options for blind search and targeted *** targeted search is specifically designed to search for interesting weak bursts,such as gravitational wave-associated gamma-ray bursts(GRBs).From the ground search of the data in the first year,GECAM has been triggered by 54 GRBs and other transients,including soft gamma-ray repeaters,X-ray binaries,solar flares,terrestrial gamma-ray *** report the properties of each type of triggers,such as trigger time and light *** this search pipeline and assuming a soft Band spectrum,the GRB detection sensitivity of GECAM is increased to about 1.1×10^(-8)erg cm^(-2)s^(-1)(10-1000 ke V,burst duration of 20 s).These results demonstrate that the GECAM ground search system(both blind search and targeted search)is a versatile pipeline to recover true astrophysical signals which were too weak to be found in the on-board search.

关键词： gamma-ray sources gravitational waves data analysis gamma-ray telescopes

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基于增材制造的交叉簧片柔性铰链设计与分析

上海航天(中英文) 2025年第1期42卷 126-133页

作者：陈霖陆秋阳赵凯岳义上海工程技术大学机械与汽车工程学院上海201620 上海航天设备制造总厂有限公司上海200245 上海复杂金属构件增材制造工程技术研究中心上海200245

柔性铰链作为柔性机构的关键部件,得到了国内外研究者的广泛关注,为探究增材制造技术应用在柔性铰链设计领域中的可行性,本文面向增材制造工艺设计了一种交叉簧片柔性铰链。首先,建立了交叉簧片柔性铰链的等效转动刚度模型。其次,选取... 详细信息

柔性铰链作为柔性机构的关键部件,得到了国内外研究者的广泛关注,为探究增材制造技术应用在柔性铰链设计领域中的可行性,本文面向增材制造工艺设计了一种交叉簧片柔性铰链。首先,建立了交叉簧片柔性铰链的等效转动刚度模型。其次,选取了簧片厚度t、孔洞尺寸a、b以及交叉角度α,3个关键设计参数设计并采用激光选区熔化(SLM)技术制作了一组铰链实例,对其进行了理论分析,采用有限元仿真,搭建了视觉测试平台对铰链实例进行测试。结果表明:铰链刚度的理论值、仿真值和实验值具有较好的一致性,验证了模型的有效性。最后,采用在簧片与基体接触处设置圆角,以及非等厚度簧片的设计对柔性铰链结构进行了优化,提升了柔性铰链结构制造稳定性,并优化了铰链的传动性能。

关键词：柔性铰链交叉簧片增材制造等效刚度弯扭耦合