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DeepSun:machine-learning-as-a-service for solar flare prediction

Research in Astronomy and Astrophysics 2021年第7期21卷 51-61页

作者： Yasser Abduallah jason T.L.Wang Yang Nie Chang Liu Haimin Wang Institute for Space Weather Sciences New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA Department of Computer Science New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA Big Bear Solar Observatory New Jersey Institute of Technology40386 North Shore LaneBig Bear CityCA 92314-9672USA Center for Solar-Terrestrial Research New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA

Solar flare prediction plays an important role in understanding and forecasting space *** main goal of the Helioseismic and magnetic Imager(HmI), one of the instruments on NASA's Solar Dynamics Observatory, is to study the origin of solar variability and characterize the Sun's magnetic *** provides continuous full-disk observations of the solar vector magnetic field with high cadence data that lead to reliable predictive capability;yet, solar flare prediction effort utilizing these data is still limited. In this paper, we present a machine-learning-as-a-service(mLaa S) framework, called Deep Sun,for predicting solar flares on the web based on HmI's data products. Specifically, we construct training data by utilizing the physical parameters provided by the Space-weather HmI Active Region Patch(SHARP)and categorize solar flares into four classes, namely B, C, m and X, according to the X-ray flare catalogs available at the National Centers for Environmental Information(NCEI). Thus, the solar flare prediction problem at hand is essentially a multi-class(i.e., four-class) classification problem. The Deep Sun system employs several machine learning algorithms to tackle this multi-class prediction problem and provides an application programming interface(API) for remote programming users. To our knowledge, Deep Sun is the first mLaa S tool capable of predicting solar flares through the internet.

关键词： Sun:flares Sun:activity methods:data analysis

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NetPrune:A sparklines visualization for network pruning

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Visual Informatics 2023年第2期7卷 85-99页

作者： Luc-Etienne Pommé Romain Bourqui Romain Giot jason Vallet David Auber Univ.Bordeaux CNRSBordeaux INPINRIALaBRIUMR 5800F-33400 TalenceFrance

Current deep learning approaches are cutting-edge methods for solving classification *** transfer learning techniques allows applying large generic model to simple tasks whereas simpler models could be *** models raise the major problem of their memory consumption and processor usage and lead to a prohibitive ecological *** that paper,we present a novel visual analytics approach to interactively prune those networks and thus limit that *** technique leverages a novel sparkline matrix visualization technique as well as a novel local metric which evaluates the discriminatory power of a filter to guide the pruning process and make it *** assess the well-founded of our approach through two realistic case studies and a user *** both of them,the interactive refinement of the model led to a significantly smaller model having similar prediction accuracy than the original one.

关键词： Explainable pruning Guided Fine-tuning Visualization Deep learning

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Nuclear physics program at mAX-lab

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Chinese Physics C 2009年第12期33卷 1159-1166页

作者： W.J. Briscoe jason Brudvik K.G. Fissum K. Hansen L. Isaksson m. Lundin B. Nilsson B. Schroder Center for Nuclear Studies The George Washington University Washington DC 20052 USA Department of Physics Lund University Lund SE-221 00 Sweden mAX-lab Lund SE-221 00 Sweden

The upgrade of the mAX-lab injector and the construction of mAX Ⅲ, provided the opportunity for upgrading the tagged-photon facility and thus lead to the possibility of more extensive program in nuclear physics research. This upgrade increased the injected electron energy to an eventual maximum of 250 meV and allows for the extraction of electrons from the mAX Ⅰ ring operated in the stretcher mode. The first stretched beam was delivered in September 2005. The tagged-photon facility was commissioned in parallel with the commissioning of new experimental equipment. The PAC approved experimental program is current in progress, including measurements of pion photoproduction below the △（1232）. The efforts at the tagged photon-facility are pursued within an international collaboration with around fifty members.

关键词： photonuclear reactions pion production compton scattering

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Adjuvant chemotherapy for intrahepatic cholangiocarcinoma: approaching clinical practice consensus?

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Hepatobiliary Surgery and Nutrition 2020年第5期9卷 577-586,I0001页

作者： Ariella m.Altman Scott Kizy Schelomo marmor Jane Y.C.Hui Todd m.Tuttle Eric H.Jensen jason W.Denbo Department of Surgery University of MinnesotaMinneapolisMNUSA Department of Gastrointestinal Oncology H.Lee Moffitt Cancer CenterTampaFLUSA

Background:Intrahepatic cholangiocarcinoma(ICC)is rare with limited evidence-based *** retrospective study evaluates the use of chemotherapy in patients with resected ***:The Surveillance Epidemiology and End Results(SEER)program database was used to identify patients with resected *** were stratified by date of diagnosis(2000-2004,2005-2009,2010-2014),T,and N *** logistic regression models identified predictors of chemotherapy ***-meier and Cox proportional hazard models were used to identify survival ***:One thousand and two hundred twenty-three patients met inclusion *** utilization increased over time(33%to 41%,P≤0.05).Chemotherapy use increased in lymph node(LN)positive patients[32%to 60%in 2010-2014;(P≤0.05)and T3/T4 disease(40%to 60%in 2010-2014;P≤0.01)],but not in patients with LN negative or T1/T2 *** positivity was associated with utilization of chemotherapy in 2005-2009 and *** survival increased from 32 to 41 months(P≤0.05).In LN positive patients,chemotherapy was associated with a decreased hazard ratio of death(P≤0.05)and T3/T4 disease was associated with an increased hazard ratio of death(P≤0.05).Conclusions:Adjuvant chemotherapy use in ICC has *** LN positive or patients with T3/T4 tumors are receiving chemotherapy,which may explain the improvement in overall survival.

关键词： Cholangiocarcinoma adjuvant chemotherapy survival lymph node(LN) surgical procedures

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Epistaxis in end stage liver disease masquerading as severe upper gastrointestinal hemorrhage

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World Journal of Gastroenterology 2014年第38期20卷 13993-13998页

作者： marine Camus Dennis m Jensen jason D matthews Gordon V Ohning Thomas O Kovacs Rome Jutabha Kevin A Ghassemi Gustavo A machicado Gareth S Dulai CURE Hemostasis Research Group CURE Digestive Diseases Research CenterDavid Geffen School of Medicine at University of California Division of Digestive Diseases at University of California Los AngelesRonald Reagan Medical Center Department of Gastroenterology Lariboisiere Hospital CURE Hemostasis Research Group CURE Digestive Diseases Research CenterDavid Geffen School of Medicine at University of CaliforniaLos AngelesLos AngelesCA 90095United States Gastroenterology Division at VA Greater Los Angeles Healthcare System Hunterdon Gastrointestinal Associates

AIm: To describe the prevalence, diagnosis, treatment, and outcomes of end stage liver disease (ESLD) patients with severe epistaxis thought to be severe upper gastrointestinal hemorrhage (UGIH).

关键词： Epistaxis Upper gastrointestinal bleeding End stage liver disease Cirrhosis Nasogastric tube Liver transplantation Digestive bleeding Nasal packing Coagulopathy

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A dual-gelling poly(N-isopropylacrylamide)-based ink and thermoreversible poloxamer support bath for high-resolution bioprinting

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Bioactive materials 2022年第8期7卷 302-312页

作者： Adam m.Navara Yu Seon Kim Yilan Xu Christopher L.Crafton mani Diba jason L.Guo Antonios G.mikos Department of Bioengineering Rice University6500 Main StreetHoustonTX77030USA

Extrusion bioprinting is a popular method for fabricating tissue engineering scaffolds because of its potential to rapidly produce complex,bioactive or cell-laden ***,due to the relatively high viscosity required to maintain shape fidelity during printing,many extrusion-based inks lack the ability to achieve precise structures at scales lower than hundreds of *** this work,we present a novel poly(N-isopropylacrylamide)(PNIPAAm)-based ink and poloxamer support bath system that produces precise,multi-layered structures on the tens of micrometers *** support bath maintains the structure of the ink in a hydrated,heated environment ideal for cell culture,while the ink undergoes rapid thermogelation followed by a spontaneous covalent crosslinking *** the combination of the PNIPAAm-based ink and poloxamer bath,this system was able to produce hydrogel scaffolds with uniform fibers possessing diameters tunable from 80 to 200μm.A framework of relationships between several important printing factors involved in maintaining support and thermogelation was also *** a whole,this work demonstrates the ability to produce precise,acellular and cell-laden PNIPAAm-based scaffolds at high-resolution and contributes to the growing body of research surrounding the printability of extrusion-based bioinks with support baths.

关键词： Bioprinting Thermogelling macromer Tissue engineering Printability

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A flexible and scalable scheme for mixing computed formation energies from different levels of theory

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npj Computational materials 2022年第1期8卷 1857-1867页

作者： Ryan S.Kingsbury Andrew S.Rosen Ayush S.Gupta jason m.munro Shyue Ping Ong Anubhav Jain Shyam Dwaraknath matthew K.Horton Kristin A.Persson Department of materials Science and Engineering University of California BerkeleyBerkeleyCA94720USA Energy Technologies Area Lawrence Berkeley National LaboratoryBerkeleyCA94720USA materials Science Division Lawrence Berkeley National LaboratoryBerkeleyCA94720USA miller Institute for Basic Research in Science University of CaliforniaBerkeleyCA94720USA University of California San Diego La JollaCA92093USA molecular Foundry Lawrence Berkeley National LaboratoryBerkeleyCA94720USA

Computational materials discovery efforts are enabled by large databases of properties derived from high-throughput density functional theory(DFT),which now contain millions of calculations at the generalized gradient approximation(GGA)level of *** is now feasible to carry out high-throughput calculations using more accurate methods,such as meta-GGA DFT;however recomputing an entire database with a higher-fidelity method would not effectively leverage the enormous investment of computational resources embodied in existing(GGA)***,we propose here a general procedure by which higher-fidelity,low-coverage calculations(e.g.,meta-GGA calculations for selected chemical systems)can be combined with lower-fidelity,high-coverage calculations(e.g.,an existing database of GGA calculations)in a robust and scalable *** then use legacy PBE(+U)GGA calculations and new r2SCAN meta-GGA calculations from the materials Project database to demonstrate that our scheme improves solid and aqueous phase stability predictions,and discuss practical considerations for its implementation.

关键词： theory scheme theory

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Exercise Catheterization for Hemodynamic Evaluation of Adults with Coarctation of the Aorta

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Congenital Heart Disease 2022年第6期17卷 605-615页

作者： Irene martin de miguel C.Charles Jain Alexander C.Egbe jason H.Anderson Heidi m.Connolly William R.miranda Department of Cardiovascular medicine Mayo ClinicRochesterMinnesotaUSA Department of Pediatric and Adolescent medicine Division of Pediatric CardiologyMayo ClinicRochesterMinnesotaUSA

Background: Coarctation of the aorta (CoA) is associated with a generalized arteriopathy and long-term complicationsdespite repair. Data on invasive exercise hemodynamics in this population are lacking. Accordingly, wereviewed adults with CoA undergoing exercise catheterization to assess 1. hemodynamic profile;2. feasibilityfor assessment of CoA severity. methods: Twenty patients undergoing exercise cardiac catheterization (12 armadduction and 8 supine cycle ergometry) at a quaternary care center between 2004 and 2021 were identified. Restingand exercise hemodynamic data were abstracted from the procedure logs. Results: mean age was 43.6 ±12.0 years. Eleven patients (55%) had resting pulmonary arterial wedge pressure (PAWP) >15 mmHg;amongthose undergoing arterial catheterization, left ventricular end-diastolic pressure was >15 mmHg in 63%. Elevenpatients (55%) had pulmonary hypertension: 7 (35%) combined and 4 (20%) isolated post-capillary. At peak exercise,ΔPAWP/Δcardiac output (CO) ≥2 and Δmean pulmonary artery pressure/ΔCO ≥3 mmHg/l/min were foundin 7 (78%) and 6 (67%) patients, respectively;the composite of exercise PAWP ≥25 mmHg or ΔPAWP/ΔCO>2 was seen in 12 (86%). CoA peak-to-peak gradients at baseline (n = 14) and during exercise (n = 9) were 12(3–16) and 16 mmHg (9–28), respectively. Only 2 patients had an increase in CoA gradient to >20 mmHg withexercise. Conclusions: Diastolic dysfunction and pulmonary hypertension were highly prevalent, with exerciseunmasking abnormal diastolic and pulmonary vascular reserve in some individuals. most patients failed to showsignificant increases in CoA peak-to-peak gradients with exercise. Further studies are warranted to establish thebest diagnostic method for CoA severity assessment.

关键词： Coarctation of the aorta exercise heart catheterization diastolic dysfunction hypertension

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基于TROPOmI NO_(2)、CO及HCHO重构数据的近地面O_(3)浓度估算研究

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遥感学报 2024年第9期28卷 2348-2361页

作者：陈小娟秦凯 Cohen jason 何秦中国矿业大学环境与测绘学院徐州221116

以TROPOmI大气成分产品为代表的卫星遥感数据在近地面臭氧(O_(3))浓度估算中表现出很好的潜力。由于云及反演算法局限性等原因,TROPOmI的大气成分产品存在一定的数据缺失,使得基于此的近地面O_(3)浓度估算数据覆盖度较低。为此,本文采... 详细信息

以TROPOmI大气成分产品为代表的卫星遥感数据在近地面臭氧(O_(3))浓度估算中表现出很好的潜力。由于云及反演算法局限性等原因,TROPOmI的大气成分产品存在一定的数据缺失,使得基于此的近地面O_(3)浓度估算数据覆盖度较低。为此,本文采用经验正交函数分解插值法(DINEOF)对TROPOmI NO_(2)、CO、HCHO原始数据产品进行缺失像元重构,并基于重构数据产品采用极限梯度提升算法(XGBoost)估算了中国大陆地区2019年—2021年高覆盖度的日最大8 h平均O_(3)浓度(mDA8 O_(3))。对比研究了DINEOF方法对TROPOmI NO_(2)、CO、HCHO原始数据产品的缺失像元进行重构后再建模估算O_(3)的方法(方案1),使用TROPOmI NO_(2)、CO、HCHO原始数据产品并对其缺失像元赋空值并输入其他特征变量来建模估算O_(3)的方法(方案2),有TROPOmI NO_(2)、CO、HCHO原始数据产品的建模结果和无TROPOmI NO_(2)、CO、HCHO原始数据产品,只有其他特征变量的建模结果相结合的方法(方案3),均可提升O_(3)模型估算结果的覆盖度。实验表明:方案1的结果最好,其十折交叉验证R^(2)=0.86,RmSE=15.86μg/m^(3),模型精度和方案2基本一致且高于方案3,在重构区域的模型精度最高(训练集R^(2)=0.82,RmSE=15.57μg/m^(3)),且当重构区域出现O_(3)重污染时(浓度大于160μg/m^(3)),能明显改善模型高值低估现象,结果的空间分布更合理。方案1估算的2019年—2021年近地面mDA8 O_(3)的平均覆盖度从33.6%提升到97.2%,使用TROPOmI NO_(2)、CO、HCHO重构数据产品建模估算O_(3)可提升模型性能和模型结果的覆盖度。

关键词：遥感近地面O_(3) TROPOmI DINEOF XGBoost 数据重构

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Systemic therapy without radiation may be appropriate as neoadjuvant therapy for localized pancreas cancer

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Hepatobiliary Surgery and Nutrition 2020年第3期9卷 296-303页

作者： Scott Kizy Ariella m.Altman Keith m.Wirth Schelomo marmor Jane Y.C.Hui Todd m.Tuttle Emil Lou Khalid Amin jason W.Denbo Eric H.Jensen Division of Surgical Oncology Department of SurgeryUniversity of MinnesotaMinneapolisMNUSA Division of Hematology and Oncology Department of Internal MedicineUniversity of MinnesotaMinneapolisMNUSA Department of Laboratory medicine and Pathology University of MinnesotaMinneapolisMNUSA

Background:The utility of neoadjuvant treatment for resectable pancreas cancer is yet to be determined,but has commonly included *** evaluated outcomes in patients with radiographically resectable pancreatic adenocarcinoma treated with neoadjuvant chemotherapy without ***:A retrospective review of patients in our institutional pancreatic cancer registry was performed,which identified 36 patients who received neoadjuvant chemotherapy alone for resectable pancreatic adenocarcinoma between 2012 and ***:median age at diagnosis was 66.3 *** regimens included gemcitabine(n=17),gemcitabine/nab-paclitaxel(n=8),or 5-FU/leucovorin/irinotecan/oxaliplatin(FOLFIRINOX)(n=11).Surgical resection was performed in 69%of patients(n=25),with an R0 resection rate of 92%(n=23 patients).During chemotherapy,distant disease became apparent in 19%of patients(n=7),while no patients had evidence of local *** rates were similar between chemotherapy regimens(single agent=59%,multiple agent=79%).median overall survival for all patients who received neoadjuvant chemotherapy was 30.3 and 34.4 months for those who underwent surgical *** was no difference in median survival for patients treated with gemcitabine(31.3 months)or multi-agent chemotherapy(29.7 months).Conclusions:A short course of neoadjuvant chemotherapy without chemoradiation may improve patient selection prior to surgical resection for pancreas ***,local disease progression did not limit surgical resection in this small series.

关键词： Pancreatic adenocarcinoma chemotherapy survival neoadjuvant chemotherapy resection

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