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Soft tissue swelling incidence using demineralized bone matrix in the outpatient setting

世界骨科杂志：英文版 2017年第10期8卷 770-776页

作者： Kingsley R Chin Fabio JR Pencle jason A Seale Juan M Valdivia Charles e. Schmidt College of Medicine at Florida Atlantic University Less ex-posure Surgery Specialists Institute Herbert Wertheim College of Medicine at Florida International University Less exposure Surgery Society

AIM To assess use of demineralized bone matrix(DBM) use in anterior cervical discectomy and fusion(ACDF) in outpatient *** One hundred and forty-five patients with prospectively collected data undergoing single and two level ACDF with DBM packed within and anterior to polyetheretherketone(PeeK) cages. Two groups created, Group 1(75) outpatients and control Group 2(70) hospital patients. Prevertebral soft tissue swelling(PVSTS) was measured anterior to C2 and C6 on plain lateral cervical radiographs preoperatively and one week postoperatively and fusion assessed at two years. ReSULTS There was no intergroup significance between preoperative and postoperative visual analogue scales(VAS)and neck disability index(NDI) scores between Group 1 and 2. Mean preoperative PVSTS in Group 1 was 4.7 ± 0.2 mm at C2 level and 11.1 ± 0.5 at C6 level compared to Group 2 mean PVSTS of 4.5 ± 0.5 mm and 12.8 ± 0.5, P = 0.172 and 0.127 respectively. There was no radiographic or clinical evidence of adverse reaction noted. In Group 1 mean postoperative PVSTS was 5.5 ± 0.4 mm at C2 and 14.9 ± 0.6 mm at C6 compared Group 2 mean PVSTS was 4.9 ± 0.3 mm at C2 and 14.8 ± 0.5 mm at C6, P = 0.212 and 0.946 respectively. No significant increase in prevertebral soft tissue space at C2 and C6 level *** ACDF with adjunct DBM packed PeeK cages showed a statistical significant intragroup improvement in VAS neck pain scores and NDI scores(P = 0.001). There were no reported serious patient complications; post-operative radiographs demonstrated no significant difference in prevertebral space. We conclude that ACDF with DBMpacked PeeK cages can be safely done in an ASC with satisfactory outcomes.

关键词： Ambulatory surgery center Anterior cervical discectomy and fusion Demineralized bone matrix Less exposure Surgery Packed polyetheretherketone cages

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estimate of the energy value of soybean meal relative to corn based on growth performance of nursery pigs

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Journal of Animal Science and Biotechnology 2020年第3期11卷 912-919页

作者： Henrique S.Cemin Hayden e.Williams Mike D.Tokach Steve S.Dritz jason C.Woodworth Joel M.DeRouchey Robert D.Goodband Kyle F.Coble Brittany A.Carrender Mandy J.Gerhart Department of Animal Sciences and Industry College of AgricultureKansas State UniversityManhattanKS 66506USA Department of Diagnostic Medicine/Pathobiology College of Veterinary MedicineKansas State UniversityManhattanKS 66506USA JBS USA GreeleyCO 80634USA

Background:Two experiments were conducted to determine the effects of increasing amounts of soybean meal(SBM)in swine diets and estimate the energy value of ***:A total of 2233 pigs(PIC 337×1050,Hendersonville,TN)and 3796 pigs(PIC 359×C40),initially 11.0 kg and 17.6 kg body weight(BW),were used in exp.1 and 2,*** exp.1,pigs were placed in 92 pens each containing 20 to 27 *** exp.2,pigs were placed in 84 pens each containing 37 to 43 *** were assigned in a randomized complete block design with BW as the blocking *** treatments consisted of 21%,27%,33%,or 39%SBM in exp.1 and 17.5%,22%,26.5%,31%,35.5%,or 40%SBM in exp.2,obtained by changing the inclusion rate of feed-grade amino acids and corn *** exp.1,representative samples of corn grain,SBM,and distillers dried grains with solubles were analyzed for total AA content prior to diet *** exp.2,diets were formulated using NRC(2012)nutrient *** diets were fed for 21 and 22 d(exp.1 and 2)and there were 23 replicates in exp.1 and 14 replicates in *** were weighed and feed disappearance measured weekly to calculate average daily gain(ADG),average daily feed intake(ADFI),gain-to-feed ratio(G:F),and caloric efficiency(Ce).Data were analyzed with block as a random effect and treatment as a fixed effect,and contrasts were constructed to test the linear and quadratic effects of increasing ***:In exp.1,there was a tendency(linear,P=0.092)for a decrease in ADFI as SBM *** was a tendency(P=0.090)for a quadratic response for ADG,with a decrease in ADG observed with 39%SBM *** fed diets with increasing SBM had a tendency(quadratic,P=0.069)for an increase in G:F up to 33%SBM and an improvement(linear,P=0.001;quadratic,P=0.063)in Ce with increasing *** Ce to estimate the energy of SBM relative to corn,a value of 105.4%of corn energy or 2816 kcal/kg Ne was determined using all data *** removing the Ce value

关键词： Caloric efficiency energy Soybean meal Swine

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Call for Papers See Special Issueon"Hybrid-augmented Intelligence in Power Systems Operation and Control"

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CSee Journal of Power and energy Systems 2022年第6期8卷 I0001-I0001,F0003页

作者： Guo jianbo Hamed Mohsenian-Rad Jun jason Zhang State Grid Corporation of China China Universityof California at Riverside USA Wuhan University China

Power systems operation and control is concerned essentially with the cognition,management,and control(CMC)process for complex power systems.A power system with high a penetration rate of renewable energies,i.e.,the"Next-Generation Power Systems",has featured characteristics of open operational environments,complex system components,diverse operational modes,tightly coupled component behaviours,stringent demand on real-time response performance,high criticality.

关键词： Hybrid Power system

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Microparticles with tunable,cell-like properties for quantitative acoustic mechanophenotyping

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Microsystems & Nanoengineering 2023年第4期9卷 129-141页

作者： Ryan Dubay eric MDarling jason Fiering Center for Biomedical engineering Brown UniversityProvidenceRI 02912USA Biological Microsystems DraperCambridgeMA 02139USA Department of Pathology and Laboratory Medicine Brown UniversityProvidenceRI 02912USA School of engineering Brown UniversityProvidenceRI 02912USA Department of Orthopaedics Brown UniversityProvidenceRI 02912USA

Mechanical properties of biological cells have been shown to correlate with their biomolecular state and function,and therefore methods to measure these properties at scale are of *** microfluidic technologies can measure the mechanical properties of cells at rates over 20,000 cells/s,which is more than four orders of magnitude faster than conventional ***,precise and repeatable means to calibrate and test these new tools remain lacking,since cells themselves are by nature ***,microfluidic tools use rigid polymer microspheres for calibration because they are widely available in cell-similar sizes,but conventional microspheres do not fully capture the physiological range of other mechanical properties that are equally important to device function(e.g.,elastic modulus and density).Here,we present for the first time development of monodisperse polyacrylamide microparticles with both tunable elasticity and tunable *** these size,elasticity,and density tunable particles,we characterized a custom acoustic microfluidic device that makes single-cell measurements of mechanical *** then applied the approach to measure the distribution of the acoustic properties within samples of human leukocytes and showed that the system successfully discriminates lymphocytes from other *** initial demonstration shows how the tunable microparticles with properties within the physiologically relevant range can be used in conjunction with microfluidic devices for efficient high-throughput measurements of mechanical properties at single-cell resolution.

关键词： tunable elasticity function

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Multilayer Neural Network Based Speech emotion Recognition for Smart Assistance

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Computers, Materials & Continua 2023年第1期74卷 1523-1540页

作者： Sandeep Kumar MohdAnul Haq Arpit Jain C.Andy jason Nageswara Rao Moparthi Nitin Mittal Zamil S.Alzamil Department of Computer Science and engineering Koneru Lakshmaiah Education FoundationVaddeswaramAP522502India Department of Computer Science College of Computer and Information SciencesMajmaah University11952Al-MajmaahSaudi Arabia Department of Computer Science and engineering Teerthanker Mahaveer UniversityMoradabadUttar Pradesh244001India Department of electronics and Communication engineering Sreyas Institute of Engineering and TechnologyHyderabad500068India University Centre for Research and Development Chandigarh UniversityMohali140413PunjabIndia

Day by day,biometric-based systems play a vital role in our daily *** paper proposed an intelligent assistant intended to identify emotions via voice message.A biometric system has been developed to detect human emotions based on voice recognition and control a few electronic peripherals for alert *** proposed smart assistant aims to provide a support to the people through buzzer and light emitting diodes(LeD)alert signals and it also keep track of the places like households,hospitals and remote areas,*** proposed approach is able to detect seven emotions:worry,surprise,neutral,sadness,happiness,hate and *** key elements for the implementation of speech emotion recognition are voice processing,and once the emotion is recognized,the machine interface automatically detects the actions by buzzer and *** proposed system is trained and tested on various benchmark datasets,i.e.,Ryerson Audio-Visual Database of emotional Speech and Song(RAVDeSS)database,Acoustic-Phonetic Continuous Speech Corpus(TIMIT)database,emotional Speech database(emo-DB)database and evaluated based on various parameters,i.e.,accuracy,error rate,and *** comparing with existing technologies,the proposed algorithm gave a better error rate and less *** rate and time is decreased by 19.79%,5.13 *** the RAVDeeS dataset,15.77%,0.01 s for the emo-DB dataset and 14.88%,3.62 for the TIMIT *** proposed model shows better accuracy of 81.02%for the RAVDeeS dataset,84.23%for the TIMIT dataset and 85.12%for the emo-DB dataset compared to Gaussian Mixture Modeling(GMM)and Support Vector Machine(SVM)Model.

关键词： Speech emotion recognition classifier implementation feature extraction and selection smart assistance

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Taking care of volunteers in a stroke trial: a new assisted-management strategy

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Stroke & Vascular Neurology 2016年第3期1卷 108-114页

作者： Amber C Stuart jason J Sico Catherine M Viscoli Ashis H Tayal Silvio e Inzucchi Gary A Ford Karen L Furie Robert Cote J David Spence David Tanne Walter N Kernan on behalf of the IRIS Trial Investigators Department of Internal Medicine Yale University School of MedicineNew HavenConnecticutUSA Department of Neurology Yale University School of MedicineNew HavenConnecticutUSA Department of Neurology Service Veterans Affairs Connecticut Healthcare SystemWest HavenConnecticutUSA Neuroscience Institute Allegheny Health NetworkPittsburghPennsylvaniaUSA Lewis Katz School of Medicine at Temple University PhiladelphiaPennsylvaniaUSA Division of Medical Sciences Oxford UniversityOxfordUK The Warren Alpert Medical School of Brown University ProvidenceRhode IslandUSA Department of Neurology Neurosurgery and MedicineMcGill UniversityMontrealQuebecCanada University of Western Ontario LondonOntarioCanada 10Sheba Medical CenterTel Aviv UniversityTel AvivIsrael 不详

Background and purpose:Providing participants with evidence-based care for secondary prevention is an ethical and scientific priority for trials in stroke *** optimal strategy,however,is *** report the performance of a new approach for delivering preventive care to trial ***:Participants were enrolled in the Insulin Resistance Intervention after Stroke trial,which examined the insulin sensitiser,pioglitazone versus placebo for prevention of stroke and myocardial infarction after ischaemic stroke or transient ischaemic *** care was the responsibility of the participants’personal healthcare providers,but investigators monitored care and provided feedback *** studied achievement of 8 prevention goals at baseline and 3 annual visits,with a focus on 3 priority goals:blood pressureensity lipoprotein(LDL)cholesterole proportion of participants achieving the priority goals was highest for antithrombotic use(96–99%in each year)and similar for blood pressure(66–72%in each year)and LDL(68–70%in each year).All 3 priority goals were achieved by 47–52%of participants in any given ***,only 22%of participants achieved all 3 goals in each ***:A strategy of monitoring care and providing feedback was associated with high average yearly achievement of 3 priority secondary prevention goals,but the majority of trial participants did not persist in being at goal over *** registration number:NCT00091949.

关键词： prevention annually goals

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evaluation of TB elimination strategies in Canadian Inuit populations:Nunavut as a case study

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Infectious Disease Modelling 2022年第4期7卷 698-708页

作者： elaheh Abdollahi Yoav Keynan Patrick Foucault jason Brophy Holden Sheffield Seyed MMoghadas Agent-Based Modelling Laboratory York UniversityM3J 1P3TorontoOntarioCanada Department of Medical Microbiology Max Rady College of MedicineUniversity of ManitobaWinnipegR3E 0T5ManitobaCanada National Collaborating Centre for Infectious Diseases University of ManitobaWinnipegR3E 0T5ManitobaCanada Department of Family Medicine Qikiqtani General HospitalIqaluitX0A 0H0NunavutCanada Department of Pediatrics University of OttawaOttawaK1N 6N5OntarioCanada Department of Paediatrics Qikiqtani General HospitalIqaluitX0A 0H0NunavutCanada

Tuberculosis(TB)continues to disproportionately affect Inuit populations in Canada with some communities having over 300 times higher rate of active TB than Canadian-born,non-Indigenous *** Tuberculosis elimination Framework has set the goal of reducing active TB incidence by at least 50%by 2025,aiming to eliminate it by *** these goals are achievable with available resources and treatment regimens currently in practice has not been *** developed an agent-based model of TB transmission to evaluate timelines and milestones attainable in Nunavut,Canada by including case findings,contact-tracing and testing,treatment of latent TB infection(LTBI),and the government investment on housing infrastructure to reduce the average house-hold *** model was calibrated to ten years of TB incidence data,and simulated for 20 years to project program *** found that,under a range of plausible scenarios with tracing and testing of 25%e100%of frequent contacts of detected active cases,the goal of 50%reduction in annual incidence by 2025 is not *** active TB cases are identified rapidly within one week of becoming symptomatic,then the annual incidence would reduce below 100 per 100,000 population,with 50%reduction being met between 2025 and *** TB from Inuit populations would require high rates of contacttracing and would extend beyond *** findings indicate that time-to-identification of active TB is a critical factor determining program effectiveness,suggesting that investment in resources for rapid case detection is fundamental to controlling TB.

关键词： Tuberculosis Inuit populations Treatment Agent-based simulation 2000 MSC 92B05

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Analysis of the record-breaking August 2021 rainfall over the Greenland Ice Sheet

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Advances in Polar Science 2023年第3期34卷 165-176页

作者： DOU Tingfeng XIe Zuowei jason e.BOX YANG Qing YANG Yifan TeNG Shiwen XU Gaojie LIU Chao LI Xichen Derek HOUTZ GONG Xun DU Zhiheng DING Minghu YU Yongqiang XIAO Cunde College of Resources and environment University of Chinese Academy of SciencesBeijing 100049China Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029China Geological Survey of Denmark and Greenland(GeUS) Copenhagen 1350Denmark Key Laboratory for Aerosol-Cloud-Precipitation of China Meteorological Administration School of Atmospheric PhysicsNanjing University of Information Science&TechnologyNanjing 210044China Swiss Federal Institute for Forest Snow and Landscape Research(WSL)Birmensdorf CH-8903Switzerland Hubei Key Laboratory of Marine Geological Resources China University of GeosciencesWuhan 430074China State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China Institute of Global Change and Polar Meteorology Chinese Academy of Meteorological SciencesBeijing 100081China State Key Laboratory of earth Surface Processes and Resource ecology Beijing Normal UniversityBeijing 100875China

Rainfall was witnessed for the first time at the highest area of the Greenland Ice Sheet on 14 August,*** thermodynamic mechanisms supporting the rainfall are revealed by eRA5 reanalysis,in-situ and satellite *** find that a strong southward intrusion of the polar vortex favored the maintenance of a deep cyclone over Baffin Island and an amplification of anticyclonic circulation over the southeastern ice sheet,which pumped warm and moist air toward Greenland from anomalously warm waters south of *** a wide swath of the ice sheet,atmospheric uplift maintained above-melting and rainfall conditions via condensation and enhanced downward infrared *** the low-level liquid clouds,the spatial extent and duration of the rainfall would have been *** the ice sheet topographic summit,the air temperature from the ground to 250 hPa level was~2℃higher than the previous record set on 12 July,*** events may occur more frequently with the decreased temperature contrast between the Arctic and the mid-latitude regions that drives highly amplified jet ***,this extreme event serves as a harbinger of a more likely wet surface condition across all elevations of the ice sheet.

关键词： Greenland Ice Sheet rainfall polar vortex liquid cloud

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evidence of bisphosphonate-conjugated sitafloxacin eradication of established methicillin-resistant *** infection with osseointegration in murine models of implant-associated osteomyelitis

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Bone Research 2023年第4期11卷 751-763页

作者： Youliang Ren jason Weeks Thomas Xue Joshua Rainbolt Karen L.de Mesy Bentley Ye Shu Yuting Liu elysia Masters Philip Cherian Charles e.McKenna Jeffrey Neighbors Frank H.ebetino edward M.Schwarz Shuting Sun Chao Xie Center for Musculoskeletal Research University of Rochester Medical CenterRochesterNY 14642USA Department of Orthopaedics University of Rochester Medical CenterRochesterNY 14642USA Department of Pathology and Center for Advanced Research Technologies University of Rochester Medical CenterRochesterNY 14642USA BioVinc LLCPasadenaCA 91107USA Department of Chemistry University of Southern CaliforniaLos AngelesCA 90089USA Department of Pharmacology Pennsylvania State UniversityHersheyPA 17033USA Department of Chemistry University of RochesterRoche

eradication of MRSA osteomyelitis requires elimination of distinct *** overcome this,we developed bisphosphonateconjugated sitafloxacin(BCS,BV600072)and hydroxybisphosphonate-conjugate sitafloxacin(HBCS,BV63072),which achieve“target-and-release”drug delivery proximal to the bone infection and have prophylactic efficacy against MRSA static biofilm in vitro and in *** we evaluated their therapeutic efficacy in a murine 1-stage exchange femoral plate model with bioluminescent MRSA(USA300LAC::lux).Osteomyelitis was confirmed by CFU on the explants and longitudinal bioluminescent imaging(BLI)after debridement and implant exchange surgery on day 7,and mice were randomized into seven groups:1)Baseline(harvested at day7,no treatment);2)HPBP(bisphosphonate control for BCS)+vancomycin;3)HPHBP(hydroxybisphosphonate control for HBCS)+vancomycin;4)vancomycin;5)sitafloxacin;6)BCS+vancomycin;and 7)HBCS+*** confirmed infection persisted in all groups except for mice treated with BCS or HBCS+*** revealed catastrophic femur fractures in all groups except mice treated with BCS or HBCS+vancomycin,which also displayed decreases in peri-implant bone loss,osteoclast numbers,and *** confirm this,we assessed the efficacy of vancomycin,sitafloxacin,and HBCS monotherapy in a transtibial implant *** results showed complete lack of vancomycin efficacy while all mice treated with HBCS had evidence of infection control,and some had evidence of osseous integrated septic implants,suggestive of biofilm *** together these studies demonstrate that HBCS adjuvant with standard of care debridement and vancomycin therapy has the potential to eradicate MRSA osteomyelitis.

关键词： implant infection overcome

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Allograft loss from acute Page kidney secondary to trauma after kidney transplantation

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World Journal of Transplantation 2017年第1期7卷 88-93页

作者： Kazuhiro Takahashi Rohini Prashar Krishna G Putchakayala William J Kane jason e Denny Dean Y Kim Lauren e Malinzak Transplant and Hepatobiliary Surgery Henry Ford Hospital Nephrology and Internal Medicine Henry Ford Hospital

We report a rare case of allograft loss from acute Page kidney secondary to trauma that occurred 12 years after kidney transplantation. A 67-year-old Caucasian male with a past surgical history of kidney transplant presented to the emergency department at a local hospital with left lower abdominal tenderness. He recalled that his cat, which weighs 15 lbs, jumped on his abdomen 7 d prior. On physical examination, a small tender mass was noticed at the incisional site of the kidney transplant. He was producing a normal amount of urine without hematuria. His serum creatinine level was slightly elevated from his baseline. Computer tomography revealed a large subscapular hematoma around the transplant kidney. The patient was observed to have renal trauma grade Ⅱ at the hospital over a period of three days, and he was finally transferred to a transplant center after his urine output significantly decreased. Doppler ultrasound demonstrated an extensive peri-allograft hypoechoic area and abnormal waveforms with absent arterial diastolic flow and a patent renal vein. Despite surgical decompression, the allograft failed to respond appropriately due to the delay in surgical intervention. This is the third reported case of allograft loss from acute Page kidney following kidney transplantation. This case reinforces that kidney care differs if the kidney is solitary or a transplant. early recognition and aggressive treatments are mandatory, especially in a case with Doppler signs that are suggestive of compression.

关键词： Page kidney Kidney transplantation Trauma Subcapsular hematoma Doppler ultrasound

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