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Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells

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Bone Research 2014年第3期2卷 139-151页

作者： Ping Wang Liang Zhao jason liu Michael D Weir Xuedong Zhou Hockin H K Xu Biomaterials & Tissue Engineering Division Department of Endodontics Prosthodontics and Operative Dentistry University of Maryland Dental School Baltimore MD 21201 USA State Key Laboratory of Oral Diseases West China Hospital of Stomatology Sichuan University Department of Orthopaedic Surgery Nanfang Hospital Southern Medical University Mechanical Engineering Department University of Maryland Baltimore County Baltimore MD 21250 USA Center for Stem Cell Biology and Regenerative Medicine University of Maryland School of Medicine Baltimore MD 21201 USA

Tissue engineering is promising to meet the increasing need for bone regeneration. Nanostructured calcium phosphate （CAP） biomaterials/scaffolds are of special interest as they share chemical/crystallographic similarities to inorganic components of bone. Three applications of nano-CaP are discussed in this review： nanostructured calcium phosphate cement （CPC）; nano-CaP composites; and nano-CaP coatings. The interactions between stem cells and nano-CaP are highlighted, including cell attachment, orientation/ morphology, differentiation and in vivo bone regeneration. Several trends can be seen：（i） nano-CaP biomaterials support stem cell attachment/proliferation and induce osteogenic differentiation, in some cases even without osteogenic supplements; （ii） the influence of nano-CaP surface patterns on cell alignment is not prominent due to non-uniform distribution of nano-crystals; （iii） nano-CaP can achieve better bone regeneration than conventional CaP biomaterials; （iv） combining stem cells with nano-CaP accelerates bone regeneration, the effect of which can be further enhanced by growth factors; and （v） cell microencapsulation in nano-CaP scaffolds is promising for bone tissue engineering. These understandings would help researchers to further uncover the underlying mechanisms and interactions in nano-CaP stem cell constructs in vitro and in vivo, tailor nano-CaP composite construct design and stem cell type selection to enhance cell function and bone regeneration, and translate laboratory findings to clinical treatments.

关键词： CPC Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells stem

I Came,I Learned, I’m Working An Ambassador Graduated from a Chinese University

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中国周刊 2003年第3期 14-15页

作者： jason liu

I never imagined the Ambassador of Romania to China, Mr. Isticioaia-Budura, would be so skilled in speaking both Chinese and English. He came in exactly at the time we appointed with a hospitable smile, making me feel... 详细信息

关键词： very I Came,I Learned m Working An Ambassador Graduated from a Chinese University of In time in that

Pakistan-beyond your expectation

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中国周刊 2004年第1期 4-7页

作者： jason liu

Few Westerners know much about Pakistan beyond media reports of Islamic fundamentalism, communal violence and martial law, but it contains some of Asia’s most mind-blowing landscapes, extraordinary trekking opportunities, a multitude of cultures and a long tradition of *** China’s neighbouring country is the site of some of the earliest human settlements, home to an ancient civilisation rivalling those of Egypt and Mesopotamia, and the crucible of two of the world’s major religions, Hinduism and Buddhism. You’ll surely get more than what you expected there. .

关键词： very

Scientific research requires patience——An interview with Charles Hard Townes,Nobel laureate

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中国周刊 2004年第1期 8-9页

作者： jason liu

Charles Hard Townes was born in Greenville, South Carolina, on July 28, 1915. the son of Henry Keith Townes, an attorney, and Ellen (Hard) Townes. He attended the Greenville public schools and then Furman University in Greenville, where he completed the requirements for the Bachelor of Science degree in physics and the Bachelor of Arts degree in Modern Languages, graduating summa cum laude in 1935, at the age of 19. Physics had fascinated him since his first course in the

关键词： An interview with Charles Hard Townes,Nobel laureate Scientific research requires patience very

Three extreme explorations

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中国周刊 2003年第12期 18-19页

作者： jason liu

The North PoleThe sun is always overhead from Spring to Autumn regardless of the hour of day or night, for the sun only rises once each year and sets once a year here at the PoleAll lines of longitude meet at this point. You can walk around the world in only a few stepsRevisit yesterday as you pass through all the time zones of the worldEvery direction you face is South and

关键词： of with as In over into Three extreme explorations from for that been

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HDR摄像机为“图像”日趋敏感的世界而活

世界电子元器件 2017年第10期 12-12页

作者： jason liu 安森美半导体

在社交媒体圈子里,流传着这个随性的说法:'无图无真相'。虽然这并不是什么严肃的情况,但它暗示了在现代化的数字互联世界里,视觉捕捉和证据变得比只是几年前更重要。随身带相机、行车记录仪、以及在工业和私人住宅中更广泛使用的安保监... 详细信息

在社交媒体圈子里,流传着这个随性的说法:'无图无真相'。虽然这并不是什么严肃的情况,但它暗示了在现代化的数字互联世界里,视觉捕捉和证据变得比只是几年前更重要。随身带相机、行车记录仪、以及在工业和私人住宅中更广泛使用的安保监控摄像机等应用是主要驱动力。事实上,我们在生活中的许多方面都可看到动态影像/视频录像的身影。虽然行车记录仪还没有成为车辆的标配,但为了确保能够确凿地证明自己没有犯错而避免不受保险保护,驾驶员普遍都会选择在后期加装行车记录仪。

关键词：摄像机 HDR 数字图像传感器视频质量

Meter-scale variation within a single transect demands attention to taxon accumulation curves in riverine microbiome studies

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Frontiers of Environmental Science & Engineering 2022年第5期16卷 115-125页

作者： Bingdi liu Lin Zhang jason H.Knouft Fangqiong Ling Department of Energy Environmental and Chemical EngineeringWashington University in St.LouisSt.LouisMO 63130USA Department of Biology Saint Louis UniversitySt.LouisMO 63103USA National Great Rivers Research and Education Center East AltonMO 62035USA Department of Computer Science and Engineering Washington University in St.LouisSt.LouisMO 63130USA Division of Biological and Biomedical Sciences Washington University in St.LouisSt.LouisMO 63110USA Division of Computational and Data Science Washington University in St.LouisSt.LouisMO 63130USA

Microbial communities inhabiting river ecosystems play crucial roles in global biogeochemical cycling and pollution *** variations in local microbial assemblages are important for detailed understanding of community assembly and developing robust biodiversity sampling ***,we intensely analyzed twenty water samples collected from a one-meter spaced transect from the near-shore to the near-center in the Meramec River in eastern Missouri,USA and examined the microbial community composition with 16S rRNA gene amplicon *** microbiomes across the transect exhibited extremely high similarity,with Pearson’s correlation coefficients above 0.9 for all pairwise community composition ***,despite the high similarity,PERMANOVA revealed significant spatial differences between near-shore and nearcenter communities(p=0.001).Sloan’s neutral model simulations revealed that within-transect community composition variation was largely explained by demographic stochasticity(R^(2)=0.89).Despite being primarily explained by neutral processes,LefSe analyses also revealed taxa from ten families of which relative abundances differed directionally from the bank to the river center,indicating an additional role of environmental ***,the local variations within a river transect can have profound impacts on the documentation of alpha ***-accumulation curves indicated that even twenty samples did not fully saturate the sampling effort at the genus level,yet four,six and seven samples were able to capture 80%of the phylum-level,family-level,and genus-level diversity,*** study for the first time reveals hyperlocal variations in riverine microbiomes and their assembly mechanisms,demanding attention to more robust sampling strategies for documenting microbial diversity in riverine systems.

关键词： Microbiome Freshwater Taxon accumulation curve Community assembly

Economical Optimization of Grid Power Factor Using Predictive Data

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IEEE/CAA Journal of Automatica Sinica 2019年第1期6卷 258-267页

作者： Chaojiong Huang jason Gu Haiying liu Yuansheng Lu Jun Luo IEEE the School of Electrical Engineering and Automation Shanghai University the Department of Electrical and Computer Engineering Dalhousie University

We present an electrical grid optimization method for economical benefit. After simplifying an IEEE feeder diagram, we build a compact smart grid system including a photovoltaic-inverter system, a shunt capacitor, an on-load tapchanger(OLTC) and transmission lines. The system power factor(PF) regulation and reactive power dispatching are indispensable to improve power quality. Our control method uses predictive weather and load data to decide engaging or tripping the shunt capacitor, or reactive power injection by the photovoltaic-inverter system, ultimately to keep the system PF in a good range. From the perspective of economics, the economical model is considered as a decision maker in our predictive data control ***-only control strategy is a common photovoltaic(PV)regulation method, which is treated as a baseline case. Simulations with GridLAB-D on profiled loads and residential loads have been carried out. The comparison results with baseline control strategy and our predictive data control method show the appreciable economical benefit of our method.

关键词： Grid optimization GridLAB-D inverter power factor predictive data control shunt capacitor

Transcranial photobiomodulation with near-infrared light:a promising therapeutic modality for Alzheimer's disease

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Neural Regeneration Research 2023年第9期18卷 1944-1945页

作者： Hanli liu Damir Nizamutdinov jason H.Huang Bioengineering Department the University of Texas at ArlingtonArlingtonTXUSA Neurosurgery Neuroscience InstituteBaylor Scott and White HealthTempleTXUSA Neurosurgery College of MedicineTexas A&M UniversityTempleTXUSA

Transcranial photobiomodulation(tPBM) is a noninvasive neuromodulation technique that delivers near-infrared(NIR) light with low irradiance(i.e.,power density in mW/cm2) in the wavelength range of 800-1070 *** recently published books or collected literature(Hamblin,2019;GonzalezLima,2021) and papers(Nizamutdinov et al. 2022)offer comprehensive reviews of the mechanism of action and potential clinical translations of tPBM for the treatment of a variety of diseases,including neurodegenerative diseases(Alzheimer’s disease(AD),and Parkinson’s disease),traumatic brain injury.

关键词： Alzheimer diseases