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Longitudinal Alterations of Local Spontaneous Brain Activity in Parkinson's Disease

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Neuroscience Bulletin 2017年第5期33卷 501-509页

作者： Qiaoling Zeng Xiaojun Guan jason c.F.Law Yan Lun Zhujing Shen Tao Guo Min Xuan Quanquan Gu Xiaojun Xu Min chen Minming Zhang Department of Radiology The Second Affiliated HospitalZhejiang University School of Medicine Department of Radiology Beijing Hospital

We used resting-state fMRI to evaluate longitu- dinal alterations in local spontaneous brain activity in Parkinson＇s disease （PD） over a 2-year period. Data were acquired from 23 PD patients at baseline and follow-up, and 27 age- and sex-matched normal controls. Regional homogeneity （ReHo） and voxel-based-morphometry （VBM） were used to identify differences in local sponta- neous brain activity and grey matter volume. With disease progression, we observed a progressive decrease in ReHo in the sensorimotor cortex, default-mode network, and left cerebellum, but increased ReHo in the supplementary motor area, bilateral temporal gyrus, and hippocampus. Moreover, there was a significant positive correlation between the rates of ReHo change in the left cerebellum and the rates of change in the Unified Parkinson＇s Disease Rating Scale-III scores. VBM revealed no significant differences in the grey matter volume among the three sets of acquisitions. We conclude that ReHo may be a suitable non-invasive marker of progression in PD.

关键词： Longitudinal Parkinson's disease Regionalhomogeneity ·Functional magnetic resonance imaging

DYNAMIcS OF PREcIPITATION AND TRANSFORMATION OF cARBIDES IN A Ni-BASE SUPERALLOY

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Acta Metallurgica Sinica(English Letters) 1989年第3期2卷 181-185页

作者： HUANG Qianyao SHI Yanyu central Iron and steel Research Institute,Ministry of Metallurgical Industry,Beijing,china Department No.5,central Iron and steel Research Institute,Ministry of Metallurgical Industry,Beijing,china

The quantitative analytical method combining the electrolytic extraction with X-ray diffraction analysis to determine the carbides and TcP in a Ni-base superalloy was *** variation of decomposition of Mc and precipitation of M_(23)c_6 and M_6c with hot exposure time at 850—1000℃ is shown to conform to hyperbolic *** elemental con- stitution of M_(23)c_6 changes continutously during the hot exposure *** the primary stage the constitution of the precipitates is(cr_(0.67)Mo_(0.13)Ni_(0.13)co_(0.07))_(23)c_*** with in- creasing cr and decreasing Mo,Ni and co it finally becomes(cr_(0.88)Mo_(0.07)Ni_(0.03)co_(0.02))_(23)c_6. The higher the hot exposure temperature,the faster the final constitution of M_(23)c_6 may be achieved.

关键词： Ni-base superalloy carbides hot exposure electrolytic extraction X-ray diffraction analysis

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低碳铝镇静钢酸溶铝控制

钢铁 1983年第6期18卷 25-30页

作者：李成栋鞍钢第三炼钢厂

低碳铝镇静钢要求钢中残留一定量的酸溶铝,以改善钢板的冲压性能、防止时效。我国规定这类钢酸溶铝含量的最佳值为0.02～0.07％。本文叙述在转炉吹炼技术操作实践中,将工厂低碳铝镇静钢的酸溶铝符合规定者达到95.8％,平均铝回收率为25... 详细信息

低碳铝镇静钢要求钢中残留一定量的酸溶铝,以改善钢板的冲压性能、防止时效。我国规定这类钢酸溶铝含量的最佳值为0.02～0.07％。本文叙述在转炉吹炼技术操作实践中,将工厂低碳铝镇静钢的酸溶铝符合规定者达到95.8％,平均铝回收率为25％的水平。对控制酸溶铝的有关因素作了技术分析。提出加铝量的计算式:AlT=Als+（0.0032/％[c]）×1.125+0.0006（T终-1600）+（0.08±0.01）。并提出了改进操作的意见。

关键词：酸溶铝回收率最佳值实收率低碳铝镇静钢终点温度高拉碳终点碳补吹钢液温度

Testing for selection on color and pattern in a mimetic radiation

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current Zoology 2012年第4期58卷 668-676页

作者： Justin YEAGER jason L. BROWN Victor MORALES Molly cUMMINGS Kyle SUMMERS Department of Biology East Carolina University Greenville NC 27858 Department of Ecology and Evolutionary Biology Tulane University New Orleans LA 70118 Department of Biology Duke University Durham NC 27708 Universidad de Ricardo Palma Lima Peru Department of Integrative Biology University of Texas Austin Texas 78712

In this paper, we analyze variation in spectral reflectance and color pattern among populations to demonstrate dra-matic divergence between four distinct morphs of the mimic poison frog Ranitomeya imitator. We also analyze genetic diver-gence in d-loop mtDNA sequences between populations. We then use coalescent-based simulations to demonstrate that the high levels of observed phenotypic divergence are not consistent with levels of genetic divergence expected under neutral drift among populations, implying an important role for selection in driving divergence between these populations .

关键词： Mullerian Mimicry Natural Selection Population Divergence coalescent

Adaptive green traffic signal controlling using vehicular communication

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Frontiers of Information Technology & Electronic Engineering 2017年第3期18卷 373-393页

作者： Erfan SHAGHAGHI Mohammad Reza JABBARPOUR Rafidah MD NOOR Hwasoo YEO jason J.JUNG Department of computer Systems and Technology University of Malaya Department of computer Engineering Islamic Azad UniversityNorth Tehran Branch Department of civil and Environmental Engineering Korea Advanced Institute of Science and Technology Department of computer Engineering Chung-Ang University

The importance of using adaptive traffic signal control for figuring out the unpredictable traffic congestion in today's metropolitan life cannot be overemphasized. The vehicular ad hoc network(VANET), as an integral component of intelligent transportation systems(ITSs), is a new potent technology that has recently gained the attention of academics to replace traditional instruments for providing information for adaptive traffic signal controlling systems(TScSs). Meanwhile, the suggestions of VANET-based TScS approaches have some weaknesses:(1) imperfect compatibility of signal timing algorithms with the obtained VANET-based data types, and(2) inefficient process of gathering and transmitting vehicle density information from the perspective of network quality of service(Qo S). This paper proposes an approach that reduces the aforementioned problems and improves the performance of TScS by decreasing the vehicle waiting time, and subsequently their pollutant emissions at intersections. To achieve these goals, a combination of vehicle-to-vehicle(V2V) and vehicle-to-infrastructure(V2I) communications is used. The V2 V communication scheme incorporates the procedure of density calculation of vehicles in clusters, and V2 I communication is employed to transfer the computed density information and prioritized movements information to the road side traffic controller. The main traffic input for applying traffic assessment in this approach is the queue length of vehicle clusters at the intersections. The proposed approach is compared with one of the popular VANET-based related approaches called Mc-DRIVE in addition to the traditional simple adaptive TScS that uses the Webster method. The evaluation results show the superiority of the proposed approach based on both traffic and network Qo S criteria.

关键词： Vehicular ad hoc network(VANET) Intelligent transportation systems(ITSs) clustering Adaptive traffic signal control Traffic controller Fuel consumption

THERMODYNAMIcS OF Fe-Nb-ce LIQUID SOLUTIONS cONTAINING TRAcE O,S AND c

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Acta Metallurgica Sinica(English Letters) 1989年第10期2卷 235-239页

作者： ZHOU Qianli DU Ting central Iron and steel Research Institute,Ministry of Metallurgical Industry,Beijing,china Senior engineer,central Iron and steel Research Institute,Ministry of Metallurgical Industry,Beijing,china

The solid oxide electrolyte galvanic cell represented by Mo/cr,cr_2O_3//ZrO_2(MgO)//[O], ce_2O_2S/Mo+ZrO_2 ceramic-metal,Mo have been used to study the thermodynamic proper- ties of Fe-Nb-ce solution containing trace carbon at 1600℃.The equilibrium constant for the reaction ce_2O_2S=2[ce]+2[O]+[S] and the standard free energy of formation of ce_2O_2S have been determined in liquid iron at 1600℃ as K=4.395×10^(-15).ΔG_(ce_2)O_2S=-514.786 kJ·mol^(-1).The interaction coefficients between cerium and niobium are found to he e_(Nd)^(ce)=-2.306,e_(Nd)^(ce)=-3.481. The equilibrium products began to contain the compound Nbc with the increase of Nh concentration in the condition of trace *** formation of Nbc is discussed in this *** standard free energy of formation of Nbc in liquid iron at 1600℃ have been de- termined as ΔG_(Nbc)=-87.111 kJ·mol^(-1).

关键词： Fe-Nb-ce liquid solution thermodynamic properties oxygen sulphur carbon

characterization and genetic manipulation of primed stem cells into a functional na?ve state with ESRRB

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World Journal of Stem cells 2016年第10期8卷 355-366页

作者： Ricardo Antonio Rossello Andreas Pfenning jason T Howard Ute Hochgeschwender Department of Science and Technology Sistema Universitario Ana G. Méndez Metropolitan University San Juan 00928 Puerto Rico Department of Biochemistry University of Puerto Rico - Medical Sciences Campus San Juan 00921 Puerto Rico Massachusetts Institute of Technology Cambridge MA 02139 United States Howard Hughes Medical Institute Chevy Chase MD 20815-6789 United States Duke Neurotransgenic Laboratory Duke University Medical Center Durham NC 27710 United States

AIM To identify differences between primed mouse embryonic stem cells(EScs) and fully functional naive EScs; to manipulate primed cells into a naive state. METHODS We have cultured 3 lines of cells from different mouse strains that have been shown to be naive or primed as determined by generating germline-transmitting *** were put through a battery of tests to measure the different features. RNA from cells was analyzed using microarrays, to determine a priority list of the differentially expressed genes. These were later validated by quantificational real-time polymerase chain reaction. Viral cassettes were created to induce expression of differentially expressed genes in the primed cells through lentiviral transduction. Primed reprogrammed cells were subjected to in-vivo incorporation *** Most results show that both primed and naive cells have similar features(morphology, proliferation rates, stem cell genes expressed). However, there were some genes that were differentially expressed in the na?ve cells relative to the primed cells. Key upregulated genes in na?ve cells include ESRRB, ERAS, ATRX, RNF17, KLF-5, and MYc. After over-expressing some of these genes the primed cells were able to incorporate into embryos in-vivo, re-acquiring a feature previously absent in these cells. cONcLUSION Although there are no notable phenotypic differences, there are key differences in gene expression between these na?ve and primed stem cells. These differences can be overcome through overexpression.

关键词： ESRRB ERAS Induced stem cells Overexpression c-myc

Magnetocrystalline Anisotropies of RFe_(10)V_2 (R=Y, Tb, Dy, Ho, and Er) and Their Hydrides

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Journal of Materials Science & Technology 1998年第5期14卷 447-450页

作者： Weiren ZHAO Jueyun PING and Ruzhang MA (Material Physics Dept., University of Science and Technology Beijing, Beijing 100083, china)(Present address: central Iron & steel Research Institute,Beijing 100081, china) Material Physics Dept. University of Science and Technology Beijing Beijing 100083 China central Iron and steel Research Institute Beijing 100081 China

The magnetocrystalline anisotropies of RFe10V2 (R=Y, Tb, Dy, Ho and Er) and their hydrides were studied by X-ray diffraction, magnetization and a.c. susceptibility measurements. The uniaxial anisotropy of Fe-sublattice and R-sublattice with positive second order Stevens αJ in RFe10V2 compounds is weakened by hydrogenation, while that of R-sublattice with negative αJ (Er) enhanced. Such a change of anisotropy causes planar-easy magnetic structures in RFe10V2 (R=Tb and Dy) at room temperature and induces spin reorientation in HoFe10V2 after hydrogenation. The change of anisotropy of R-sublattice after hydrogenation may be owed to a decrease of the second order crystalline coefficient.

关键词： Ho and Er and Their Hydrides V2 R=Y Dy Magnetocrystalline Anisotropies of RFe

DeepSun:machine-learning-as-a-service for solar flare prediction

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Research in Astronomy and Astrophysics 2021年第7期21卷 51-61页

作者： Yasser Abduallah jason T.L.Wang Yang Nie chang Liu Haimin Wang Institute for Space Weather Sciences New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA Department of computer Science New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA Big Bear Solar Observatory New Jersey Institute of Technology40386 North Shore LaneBig Bear CityCA 92314-9672USA center for Solar-Terrestrial Research New Jersey Institute of TechnologyUniversity HeightsNewarkNJ 07102-1982USA

Solar flare prediction plays an important role in understanding and forecasting space *** main goal of the Helioseismic and Magnetic Imager(HMI), one of the instruments on NASA's Solar Dynamics Observatory, is to study the origin of solar variability and characterize the Sun's magnetic *** provides continuous full-disk observations of the solar vector magnetic field with high cadence data that lead to reliable predictive capability;yet, solar flare prediction effort utilizing these data is still limited. In this paper, we present a machine-learning-as-a-service(MLaa S) framework, called Deep Sun,for predicting solar flares on the web based on HMI's data products. Specifically, we construct training data by utilizing the physical parameters provided by the Space-weather HMI Active Region Patch(SHARP)and categorize solar flares into four classes, namely B, c, M and X, according to the X-ray flare catalogs available at the National centers for Environmental Information(NcEI). Thus, the solar flare prediction problem at hand is essentially a multi-class(i.e., four-class) classification problem. The Deep Sun system employs several machine learning algorithms to tackle this multi-class prediction problem and provides an application programming interface(API) for remote programming users. To our knowledge, Deep Sun is the first MLaa S tool capable of predicting solar flares through the internet.

关键词： Sun:flares Sun:activity methods:data analysis