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deep learning acceleration of multiscale superresolution localization photoacoustic imaging

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Light(Science & Applications) 2022年第6期11卷 1166-1177页

作者： Jongbeom Kim Gyuwon Kim Lei Li Pengfei Zhang Jin Young Kim Yeonggeun Kim Hyung ham Kkim Lihong V.Wang Seungchul Lee Chulhong Kim departments of Electrical Engineering Mechanical EngineeringConvergence IT Engineeringand Interdisciplinary Bioscience and BioengineeringGraduate School of Artificial IntelligenceMedical Device Innovation CenterPohang University of Science and Technology(POSTECH)77 Cheongam-roNam-guPohangGyeongbuk 37673Republic of Korea Caltech Optical Imaging Laboratory Andrew and Peggy Cherng Department of Medical EngineeringDepartment of Electrical EngineeringCalifornia Institute of Technology1200 E.California Blvd.MC 138-78PasadenaCA 91125USA School of Precision Instruments and Optoelectronics Engineering Tianjin University92 Weijin RoadNankai DistrictTianjin 300072China Opticho 532CHANGeUP GROUND87 Cheongam-roNam-guPohangGyeongsangbuk 37673Republic of Korea

A superresolution imaging approach that localizes very small targets,such as red blood cells or droplets of injected photoacoustic dye,has significantly improved spatial resolution in various biological and medical imaging ***,this superior spatial resolution is achieved by sacrificing temporal resolution because many raw image frames,each containing the localization target,must be superimposed to form a sufficiently sampled high-density superresolution ***,we demonstrate a computational strategy based on deep neural networks(dNNs)to reconstruct high-density superresolution images from far fewer raw image *** localization strategy can be applied for both 3d label-free localization optical-resolution photoacoustic microscopy(OR-PAm)and 2d labeled localization photoacoustic computed tomography(PACT).For the former,the required number of raw volumetric frames is reduced from tens to fewer than *** the latter,the required number of raw 2d frames is reduced by 12 ***,our proposed method has simultaneously improved temporal(via the dNN)and spatial(via the localization method)resolutions in both label-free microscopy and labeled ***-learning powered localization PA imaging can potentially provide a practical tool in preclinical and clinical studies requiring fast temporal and fine spatial resolutions.

关键词： deep frames networks

multi-redox phenazine/non-oxidized graphene/cellulose nanohybrids as ultrathick cathodes for high-energy organic batteries

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Nano Research 2021年第5期14卷 1382-1389页

作者： Youngjin ham Vitalii Ri Jin Kim Yeoheung Yoon Jinho Lee Kisuk Kang Ki-Seok An Chunjoong Kim Seokwoo Jeon department of materials Science and Engineering Advanced Battery CenterKorea Advanced Institute of Science and Technology(KAIST)Daejeon34141Republic of Korea department of materials Science and Engineering Chungnam National UniversityDaejeon34134Republic of Korea Thin Film materials Research Center Korea Research Institute of Chemical Technology(KRICT)Daejeon34114Republic of Korea department of materials Science and Engineering Seoul National UniversitySeoul08826Republic of Korea

Various redox-active organic molecules can serve as ideal electrode materials to realize sustainable energy storage systems. Yet, to be more appropriate for practical use, considerable architectural engineering of an ultrathick, high-loaded organic electrode with reliable electrochemical performance is of crucial importance. Here, by utilizing the synergetic effect of the non-covalent functionalization of highly conductive non-oxidized graphene flakes (NOGFs) and introduction of mechanically robust cellulose nanofiber (CNF)-intermingled structure, a very thick (≈ 1 mm), freestanding organic nanohybrid electrode which ensures the superiority in cycle stability and areal capacity is reported. The well-developed ion/electron pathways throughout the entire thickness and the enhanced kinetics of electrochemical reactions in the ultrathick 5,10-dihydro-5,10-dimethylphenazine/NOGF/CNF (dmPZ-NC) cathodes lead to the high areal energy of 9.4 mWh·cm−2 (= 864 Wh·kg−1 at 158 W·kg−1). This novel ultrathick electrode architecture provides a general platform for the development of the high-performance organic battery electrodes.

关键词： energy storage organic electrodes batteries graphene cellulose nanofibers

Fundamental principles and development of proximity-field nanopatterning toward advanced 3d nanofabrication

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Nano Research 2021年第9期14卷 2965-2980页

作者： Sang-Hyeon Nam Gayea Hyun donghwi Cho Seonggon Han Gwangmin Bae Haomin Chen Kisun Kim Youngjin ham Junyong Park Seokwoo Jeon department of materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea department of mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina School of materials Science and Engineering Kumoh National Institute of TechnologyGumiGyeongbuk 39177Republic of Korea department of Energy Engineering Convergence Kumoh National Institute of TechnologyGumiGyeongbuk 39177Republic of Korea KAIST Institute for NanoCentury(KINC) KAISTDaejeon 34141Republic of Korea

Three-dimensional(3d)nanoarchitectures have offered unprecedented material performances in diverse applications like energy storages,catalysts,electronic,mechanical,and photonic *** outstanding performances are attributed to unusual material properties at the nanoscale,enormous surface areas,a geometrical uniqueness,and comparable feature sizes with optical *** the practical use of the unusual nanoscale properties,there have been developments for macroscale fabrications of the 3d nanoarchitectures with process areas over centimeter *** the many fabrication methods for 3d structures at the nanoscale,proximity-field nanopatterning(PnP)is one of the promising techniques that generates 3d optical holographic images and transforms them into material structures through a lithographic *** conformal and transparent phase masks as a key factor,the PnP process has advantages in terms of stability,uniformity,and reproducibility for 3d nanostructures with periods from 300 nm to several *** merits of realizing precise 3d features with sub-100 nm and rapid processes are attributed to the interference of coherent light diffracted by phase *** this review,to report the overall progress of PnP from 2003,we present a comprehensive understanding of PnP,including its brief history,the fundamental principles,symmetry control of 3d nanoarchitectures,material issues for the phase masks,and the process area expansion to the wafer-scale for the target ***,technical challenges and prospects are discussed for further development and practical applications of the PnP technique.

关键词： proximity-field nanopatterning three-dimensional(3d)nanostructures phase mask interference lithography

On the mHd squeeze flow between two parallel disks with suction or injection via ham and HPm

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Frontiers of mechanical Engineering 2014年第3期9卷 270-280页

作者： d. d. GANJI m. ABBASI J. RAHImI m. GHOLAmI I. RAHImIPETROUdI department of mechanical Engineering Babol University of Technology Babol Iran department of mechanical Engineering Sari Branch Islamic AzadUniversity Sari Iran department of Electrical and Computer Engineering Babol Universityof Technology Babol Iran department of mechanical Engineering College of Mechanic TehranScience and Research Branch Islamic Azad University Darnavand Iran

An analysis has been performed to study the problem of magneto-hydrodynamic （mHd） squeeze flow of an electrically conducting fluid between two infinite, parallel disks. The analytical methods called Homotopy Analysis method （ham） and Homotopy Perturbation method （HPm） have been used to solve nonlinear differential equations. It has been attempted to show the capabilities and wide-range applications of the proposed methods in comparison with a type of numerical analysis as Boundary Value Problem （BVP） in solving this problem. Also, the velocity fields have been computed and shown graphically for various values of physical parameters. The objective of the present work is to investigate the effect of squeeze Reynolds number, Hartmann number and the suction/injection parameter on the velocity field. Furthermore, the results reveal that ham and HPm are very effective and convenient.

关键词： Homotopy Analysis method Homotopy Perturbation method incompressible flow magneto-hydrodynamic flow parallel disks

Unsteady time-dependent incompressible Newtonian fluid flow between two parallel plates by homotopy analysis method(ham),homotopy perturbation method(HPm)and collocation method(Cm)

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Propulsion and Power Research 2018年第3期7卷 247-256页

作者： m.R.Shirkhani H.A.Hoshyar I.Rahimipetroudi H.Akhavan d.d.Ganji department of mechanical Engineering Sari BranchIslamic Azad UniversitySariIran Young Researchers Club Sari BranchIslamic Azad UniversitySariIran department of mechanical Engineering Ghaemshahr BranchIslamic Azad UniversityGhaemshahrIran

Analytical and numerical analyses have performed to study the problem of the flow of incompressible Newtonian fluid between two parallel plates approaching or receding from each other *** Navier–Stokes equations have been transformed into an ordinary differential equation using a similarity *** powerful analytical methods called collocation method(Cm),the homotopy perturbation method(HPm),and the homotopy analysis method(ham)have been used to solve nonlinear differential *** has been attempted to show the capabilities and wide-range applications of the proposed methods in comparison with a type of numerical analysis as fourth-order Runge–Kutta numerical method in solving this ***,velocity fields have been computed and shown graphically for various values of physical *** objective of the present work is to investigate the effect of Reynolds number and suction or injection characteristic parameter on the velocity field.

关键词： Homotopy analysis method(ham) Collocation method(Cm) Homotopy perturbation method(HPm) Parallel porous plates Unsteady flow

Application of marker Assisted Backcrossing to Introgress the Submergence Tolerance QTL <i>SUB</i>1 into the Vietnam Elite Rice Variety-AS996

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American Journal of Plant Sciences 2012年第4期3卷 528-536页

作者： Luu m. Cuc Luu T. N. Huyen Pham T. m. Hien Vu T. T. Hang Nguyen Q. dam Pham T. mui Vu d. Quang Abdelbagi m. Ismail Le H. ham Agricultural Genetics Institute Tu Liem Vietnam Cuu Long River delta Rice Research Institute Tan Thanh Vietnam International Rice Research Institute Metro Manila Philippine

The result of the study contributes to enhancing and sustaining future livelihoods and food security in Vietnam vis-a-vis climate change. An innovative strategy based on marker-assisted backcrossing (mABC) was used to transform popular rice variety AS996 into the one can tolerate submergence while maintaining its original characteristics preferred by farmers and consumers. The submergence tolerance QTL SUB1 counts for up to 70% of the submergence tolerant and provides a marked improvement of submergence tolerance in all genetic backgrounds and environments tested so far. Parental diversity was carried out with 460 markers. Of which, 53 polymorphic markers were used for assessment on BC1F1, BC2F1 and BC3F1 generations. The best BC1F1 plant was P422 with highest recipient allele was 87.5%, while the additional chosen plants were P412, P428, P215 and P39 (81% - 84%). All these plants were used to develop BC2F1 generation. The six BC2F1 plants were used to develop BC3F1 and BC2F2 were the plants number P422-11 and P422-14 having 93.75% recipient alleles and P422-12, P422-3, P39-17, P39-25 having 92.25% recipient alleles. Total of 445 BC3F1 plants were confirmed the introgresion of SUB1 using ART5 and SC3. After three generations of backcrossing, application of mABC resulted in the best BC3F1 individual P422-14-177 with 100% of recipient alleles based on the number of 53 markers used with only the introgression size of SUB1 was 0.3mb between ART5 and SC3. Phenotyping was carried out on BC3F1 and BC2F2 of the selected lines. The survival ratio of these selected lines and IR64SUB1 were the same. It convinced the successfully introgress SUB1 into AS996 rice variety. The breeding line BC4F1 having 100% genetic background of donor variety is ready for develop new submergence tolerant rice variety ASS996-SUB1 to cope with climate change.

关键词： AS996-SUB1 Climate Change marker-Assisted Backcrossing (mABC) Rice Submergence

A continental back-arc setting for the Namaqua belt:Evidence from the Kakamas domain

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Geoscience Frontiers 2022年第4期13卷 193-221页

作者： P.H.macey R.J.Thomas A.F.m.Kisters J.F.A.diener m.Angombe S.doggart C.A.Groenewald C.W.Lambert J.A.miller H.minnaar H.Smith H.F.G.moen E.muvangua A.Nguno G.Shifotoka J.Indongo d.Frei C.Spencer P.le Roux R.A.Armstrong C.Tinguely Council for Geoscience P.O.Box 572BellvilleSouth Africa department of Geology University of StellenboschSouth Africa department of Geological Sciences University of Cape TownSouth Africa Geological Survey of Namibia WindhoekNamibia department of Geology University of Free StateSouth Africa department of Earth Sciences University of the Western CapeSouth Africa The Institute of Geoscience Research Dept.Applied GeologyCurtin UniversityPerthAustralia department of Geological Sciences and Geological Engineering Queen’s UniversityKingstonCanada Geochronology and Tracers Facility British Geological SurveyNottingham NG125GGUK RSES Australian NationalUniversityCanberraACTAustralia

A study of the NW Kakamas domain in South Africa/Namibia provides a new,unified lithostratigraphy and evolutionary history applicable to the whole Namaqua *** mesoproterozoic history ranges from~1350 ma to 960 ma,but isotopic evidence suggests it was built upon pre-existing Paleoproterozoic continental crust that extended west from the Archaean *** eastern Namaqualand,early rift-related magmatism and sedimentation at~1350 ma occurred in a confined ocean *** tectonic reversal and subduction at~1290–1240 ma led to establishment of the Areachap,Konkiep and Kaaien *** the Kakamas domain,widespread deposition of pelitic sediments occurred at~1220 ma(Narries Group).These contain detrital zircons derived from proximal crust with ages between~2020 ma and 1800 ma(western Palaeoproterozoic domains)and 1350–1240 ma(eastern early Namaqua domains),suggesting pre-sedimentation *** pelites underwent granulite grade metamorphism at~1210 ma(peak conditions:4.5–6 kbar and 770–850°C),associated with voluminous,predominantly S-type granitoid orthogneisses between~1210 ma and 1190 ma(Eendoorn and ham River Suites)and low-angle ductile(d_(2))deformation which continued until~1110 ma,interspersed with periods of *** enduring P-T regime is inconsistent with the expected crustal over-thickening associated with the generally-accepted collision-accretion Namaqualand ***,we propose the Namaqua Sector is a‘hot orogen’developed in a wide continental back-arc with subduction west of the present-day *** observed high geotherm resulted from thinned back-arc lithosphere accompanied by an influx of mantle-derived *** d_(2)deformation resulted from"bottom-driven"tectonics and viscous drag within the crust by convective flow in the underlying asthenospheric *** extended tectonothermal regime ceased at~1110 ma when SW-directed thrusting stacked the Namaqua domains into their current positions,constrained in

关键词： Kakamas Namaqua Geodynamics Geochronology Hot orogeny mesoproterozoic

Groundwater Exploration Using 2-d Geoelectrical Resistivity Imaging Technique at Sungai. Udang, melaka

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Journal of Earth Science and Engineering 2012年第10期2卷 624-630页

作者： Zeinab Asry Abdul Rahim Samsudin Wan Zuhairi Yaacob jasni Yaakub Faculty of Science and Technology Universiti Kebangsaan Malaysia Bangi 43600 Malaysia Institute Lestari University Kebangsaan Malaysia Bangi 43600 Malaysia

Electrical resistivity imaging surveys have been conducted in order to locate, delineate subsurface water resource and estimate its reserve. The resistivity imaging surveys carried out basically measure and map the resistivity of subsurface materials. Electrical imaging is an appropriate survey technique for areas with complex geology where the use of resistivity sounding and other techniques are unsuitable to provide detailed subsurface information. The purpose of electrical surveys is to determine the subsurface resistivity distribution by making measurements on the ground surface. The resistivity imaging measurement employing Wenner electrode configuration was carried out using an ABEm SAS 1000 terrameter and electrode selector system ES464. The field survey was conducted along four profiles which provide a continuous coverage of the resistivity imaging below surface. The surface soil material is mainly clayey silt. The results showed that the layers associated with the low resistivities (?·m) are located at depth ranging from 2 m to 28 m. This low resistivity values are associated with zone of water saturated weathered layer and fractures. The results showed that the thickness of residual soil is about 0.5-2.55 m. Borehole data indicated that the depth of bedrock is about 10 m and the groundwater level is ranging from 8.73 m to 8.54 m.

关键词：成像测井技术电阻率成像地下水勘查马六甲地电测量技术复杂地质条件电极结构

金黄地鼠腹侧前列腺在体修饰精子膜蛋白作用研究

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中山大学学报（医学科学版） 2008年第3期29卷 241-247页

作者：骆建民郑玉鸾周白菡汕头大学医学院神经修复研究室广东汕头515031 香港大学李嘉诚医学院生物化学系中国香港香港中文大学解剖系中国香港

【目的】在整体水平探讨前列腺分泌蛋白对金黄地鼠精子膜蛋白的影响。【方法】雄性鼠手术分为4组,分别为附属性腺全去组,腹前列腺摘除组,去除其他附属性腺仅保留腹前列腺组和假手术组,每组动物6只。收集与保留前列腺及去除组的雄性鼠交... 详细信息

【目的】在整体水平探讨前列腺分泌蛋白对金黄地鼠精子膜蛋白的影响。【方法】雄性鼠手术分为4组,分别为附属性腺全去组,腹前列腺摘除组,去除其他附属性腺仅保留腹前列腺组和假手术组,每组动物6只。收集与保留前列腺及去除组的雄性鼠交配后的子宫腔精子,抽提精子膜蛋白,膜蛋白经聚丙烯酰胺凝胶(SdS-PAGE)和二维电泳凝胶分析,比较前列腺存在与否精子膜蛋白组分的异同。【结果】与不同组雄鼠交配后收集的子宫腔精子膜蛋白SdS-PAGE电泳谱主要条带类似,含腹前列腺组的精子膜组分中相对分子质量15k、29k、38k、55k和91k多肽的量较去除腹前列腺组的子宫腔精子膜相应组分增加。二维电泳结果示与含腹前列腺组雄鼠交配后收集的子宫腔精子膜蛋白较无腹前列腺组的精子膜蛋白多出10个蛋白斑点(mm/IP分别为16k/8.60、16.5k/9.2、28k/5.88/6.10、29k/5.98、32k/6.35/6.50/7.20、61k/5.90、83k/6.40),另外蛋白斑点量增加有11个。【结论】腹前列腺可修饰和调节精子膜蛋白,进而这些蛋白可能对雄性生殖力及胚胎的发育起作用。

关键词：金黄地鼠前列腺子宫腔精子膜蛋白