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Association between moderately oxidized low-density lipoprotein and high-density lipoprotein particle subclass distribution in hemodialyzed and post-renal transplant patients

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第5期12卷 365-371页

作者： Elzbieta KIMAK Magdalena HALABI Iwona BARANOWICZ-GASZCZYK janusz solski Andrzej KSIAZEK Department of Laboratory Diagnostics Medical University of Lublin Department of Nephrology Medical University of Lublin

Disturbances in the metabolism of lipoprotein profiles and oxidative stress in hemodialyzed （HD） and post-renal transplant （Tx） patients are proatherogenic, but elevated concentrations of plasma high-density lipoprotein （HDL） reduce the risk of cardiovascular disease. We investigated the concentrations of lipid, lipoprotein, HDL particle, oxidized low-density lipoprotein （ox-LDL） and anti-ox-LDL, and paraoxonase-1 （PON-1） activity in HD （n=33） and Tx （n=71） patients who were non-smokers without active inflammatory disease, liver disease, diabetes, or malignancy. HD patients had moderate hypertriglyceridemia, normocholesterolemia, low HDL-C, apolipoprotein A-I （apoA-I） and HDL particle concentrations as well as PON-1 activity, and increased ox-LDL and anti-ox-LDL levels. Tx patients had hypertriglyceridemia, hypercholesterolemia, moderately decreased HDL-C and HDL particle concentrations and PON-1 activity, and moderately increased ox-LDL and anti-ox-LDL levels as compared to the reference, but ox-LDL and anti-ox-LDL levels and PON-1 activity were more disturbed in HD patients. However, in both patient groups, lipid and lipoprotein ratios （total cholesterol （TC）/HDL-C, LDL-C/HDL-C, triglyceride （TG）/HDL-C, HDL-C/non-HDL-C, apoA-I/apoB, HDL-C/apoA-I, TG/HDL） were atherogenic. The Spearman＇s rank coefficient test showed that the concentration of ox-LDL correlated positively with HDL particle level （R=0.363, P=0.004）, and negatively with TC （R=-0.306, P=0.012）, LDL-C （R=-0.283, P=0.020）, and non-HDL-C （R=-0.263, P=0.030） levels in Tx patients. Multiple stepwise forward regression analysis in Tx patients demonstrated that ox-LDL concentration, as an independent variable, was associated significantly positively with HDL particle level. The results indicated that ox-LDL and de- creased PON-1 activity in Tx patients may give rise to more mildly-oxidized HDLs, which are less stable, easily undergo metabolic remodeling, generate a greater number of smaller pre-13-HDL particle

关键词： Lipids Lipoproteins Paraoxonase-1 (PON-1) activity Oxidized low-density lipoprotein (ox-LDL) High-density lipoprotein (HDL) particles Post-renal transplant Hemodialysis

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Some corrections to the Thomas-Fermi theory

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Chinese Physics B 2013年第8期22卷 551-556页

作者： janusz Chrzanowski Institute of Physics Maritime University of Szczecin 1-2 Waly ChrobregoSzczecin 70-500 Poland

In the presented model the wave function describing the electron is a superposition of contributions from individual components of the system, in the case of metals -- lattice ions and in this sense refers not to a single electron, but rather to the system as a whole. An unconventional approach to the Schrtdinger equation can provide a simple analytical relationship between the total energy of the electron and the wave number. This expression can directly determine the basic parameters such as Fermi radius, the screening radius or work function and also produce a graphical interpretation of the Fermi surface.

关键词： screening parameter convolution Fermi surface

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The Semigroup of Surjective Transformations on an Infinite Set

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Algebra Colloquium 2019年第1期26卷 9-22页

作者： janusz Konieczny Department of Mathematics University of Mary Washington Fredericksburg VA 22401 USA

For an infinite set X, denote by Ω(X) the semigroup of all surjective mappings from X to X. We determine Green's relations in Ω(X), show that the kernel (unique minimum ideal) of Ω(X) exists and det ermine its elemen ts and cardinali ty. For a cou ntably infinite set X, we describe the elements of Ω(X) for which the D-class and J-class coincide. We compare the results for Ω(X) with the corresponding results for other transformation semigroups on X.

关键词： transformation semigroups surjective transformations Green's relations kernels

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Flow Control Effect on Unsteadiness of Shock Wave Induced Separation

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Journal of Thermal Science 2013年第6期22卷 511-516页

作者： Piotr Doerffer janusz Telega Institute of Fluid Flow Machinery Polish Academy of Sciences

In usual cases of significant pressure gradients and strong shocks, the front shock takes a fixed location along the wall, at which separation starts. Usually the rear shock is responding to vortex sheding by its deflection angle. In consequence main shock and rear shocks are moving whilst front shock is stable. The goal of the measurements presented here is to find out how the k-foot behaves during shock oscillations in the case when front shock is not fixed by the pressure gradient. Unsteady shock behaviour is also investigated when air jet vortex generators （AJVG） are used. Counteraction of the separation is directly related to the influence on unsteady processes in the shock wave induced separation.

关键词： shock wave boundary layer interaction unsteady effects separation

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General neutrino mass spectrum and mixing properties in seesaw mechanisms

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Chinese Physics C 2021年第2期45卷 152-164页

作者： Wojciech Flieger janusz Gluza Institute of Physics University of SilesiaKatowicePoland Faculty of Science University of Hradec KrálovéCzech Republic

Neutrinos stand out among the elementary particles because of their unusually small *** seesaw mechanisms attempt to explain this *** this work,applying insights from matrix theory,we are in a position to treat variants of seesaw mechanisms in a general ***,using Weyl's inequalities,we discuss and rigorously prove under which conditions the seesaw framework leads to a mass spectrum with exactly three light *** find an estimate of the mass of heavy neutrinos to be the mass obtained by neglecting light neutrinos,shifted at most by the maximal strength of the coupling to the light neutrino *** provide analytical conditions allowing one to prescribe that precisely two out of five neutrinos are *** higher-dimensional cases the inverse eigenvalue methods are *** particular,for the CP-invariant scenarios we show that if the neutrino sector has a valid mass matrix after neglecting the light ones,*** the respective mass submatrix is positive definite,then large masses are provided by matrices with large elements accumulated on the ***,the Davis-Kahan theorem is used to show how masses affect the rotation of light neutrino eigenvectors from the standard Euclidean *** general observation concerning neutrino mixing,together with results on the mass spectrum properties,opens directions for further neutrino physics studies using matrix analysis.

关键词： neutrino mass matrix seesaw mechanism matrix theory

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Assessment of tectonic control on the development of low mountains moderate relief in the Outer Carpathians(Southern Poland)

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Journal of Mountain Science 2020年第10期17卷 2297-2320页

作者： janusz GODZIEK Krzysztof GAIDZIK Faculty of Natural Sciences University of SilesiaBedzinska 6041-200 SosnowiecPoland Institute of Earth Sciences University of SilesiaBędzińska 6041-200 SosnowiecPoland

Inherited tectonic structures,ongoing tectonic deformation,and variations in relative rock uplift rates play an important role in conditioning the processes of relief *** influence among other factors,such as climate and lithology,can be quantified using landscape analysis,and geomorphometric indices,in *** usage of landscape analysis in recent years is increasing systematically due to the constant improvement of the digital elevation models and GIS software that significantly facilitate this *** this study,we aim to recognize the influence of tectonic structures and processes on relief development in the low mountains with moderate relief of the Sola River catchment in the Western Outer *** this end,we calculated geomorphometric indices(river longitudinal profile,stream-length gradient index,minimum bulk erosion,relief ratio,circulatory ratio,elongation ratio,and hypsometric integral)for the Sola River and its 47 sub-catchments using a 25-m spatial resolution Digital Terrain Elevation Data Level ***,we identified lineaments and knickpoints and correlated the computed results with local and regional fault networks,variations in lithology,and climate *** results indicate a significant impact of inherited tectonicstructures on the relief development of the Sola River catchment,i.e.,directions of principal ridges and valleys follow the orientation of main folds and faults recorded in this *** high values of minimum bulk erosion,river gradient,and streamlength gradient index allowed us to define two areas with higher relative uplift rates:1)the So?a Gorge and 2)the Beskid Zywiecki *** Outer Carpathians are generally considered as an area of low strain rate and low seismic ***,the possibility of neotectonic processes should be considered in geohazard *** bends in the direction of river valleys that do not correspond with changes in lithology could be

关键词： Tectonics Landscape analysis Relief development Geomorphometric indices Digital elevation model Outer Carpathians

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Time-course monitoring of in vitro biotransformation reaction via solid-phase microextraction-ambient mass spectrometry approaches

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Journal of Pharmaceutical Analysis 2022年第1期12卷 186-191页

作者： Karol Jaroch janusz Pawliszyn Department of Chemistry University of WaterlooWaterlooN2L 3G1Canada Department of Pharmacodynamics and Molecular Pharmacology Faculty of PharmacyCollegium Medicum in BydgoszczNicolaus Copernicus University in Toruń Poland85090BydgoszczPoland

The solid-phase microextraction technique quantifies analytes without considerably affecting the sample ***,a proof-of-concept study was conducted to demonstrate the use of coated probe electrospray ionization(coated-PESI)and coated blade spray(CBS)as ambient mass spectrometry approaches for monitoring drug *** ability of these methods was investigated for monitoring the dephosphorylation of a prodrug,combretastatin A4 phosphate(CA4P),into its active form,combretastatin A4(CA4),in a cell culture medium supplemented with fetal bovine *** CBS spot analysis was modified to achieve the same extraction efficiency as protein precipitation and obtained results in 7 *** coated-PESI performs extraction without consuming any samples,it is the preferred technique in the case of a limited sample *** coated-PESI only extracts small quantities of analytes,it uses the desorption solvent volume of 5-10 pL,resulting in high sensitivity,thus allowing the detection of compounds after only 1 min of *** biotransformation of CA4P into CA4 via phosphatases occurs within the simple matrix,and the proposed sample preparation techniques are suitable for monitoring the biotransformation.

关键词： Solid-phase microextraction Coated probe electrospray ionization Coated blade spray Combretastatin Biotransformation Prodrug activation

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A NOVEL DESIGN OF COMPOSITE WATER TURBINE USING CFD

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Journal of Hydrodynamics 2012年第1期24卷 11-16页

作者： PIECHNA janusz MLLER Norbert Turbomachinery Laboratory Department of Mechanical EngineeringMichigan State UniversityEast LansingUSA

This paper presents computational investigation of a novel design of composite material axial water turbine using Computational Fluid Dynamics（CFD）.Based on three-dimensional numerical flow analysis,the flow characteristics through the water turbine with nozzle,wheel and diffuser are *** extract power and torque of a composite water turbine at different rotating speeds were calculated and analyzed for a specific flow *** simulation results show that using nozzle and diffuser can increase the pressure drop across the turbine and extract more power from available water *** results provide a fundamental understanding of the composite water turbine,and this design and analysis method is used in the design process.

关键词： water turbine composite material Computational Fluid Dynamics(CFD) extracted power

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ON A FIXED POINT THEOREM IN 2-BANACH SPACES AND SOME OF ITS APPLICATIONS

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Acta Mathematica Scientia 2018年第2期38卷 377-390页

作者： janusz BRZDEK Krzysztof CIEPLINSKI Pedagogical University Department of Mathematics AGH University of Science and Technology Faculty of Applied Mathematics

The aim of this article is to prove a fixed point theorem in 2-Banach spaces and show its applications to the Ulam stability of functional equations. The obtained stability re- sults concern both some single variable equations and the most important functional equation in several variables, namely, the Cauchy equation. Moreover, a few corollaries corresponding to some known hyperstability outcomes are presented.

关键词： fixed point theorem 2-normed space Ulam stability hyperstability

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Complex experimental analysis of rifle-shooter interaction

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Defence Technology（防务技术） 2017年第5期13卷 346-352页

作者： Michal Taraszewski janusz Ewertowski Warsaw University of Technology Faculty of Production EngineeringDepartment of Mechanics and Armament Technologyul.Narbutta 8502-524 WarszawaPoland

In this study, a complex analysis of a man-weapon interaction based on experimental effort is *** attention is focused on how a shooter can influence on a rifle, opposite to generally considered in literature rifle's impact on a shooter. It is shown, based on the kbk AKM weapon, that each support point of the rifle has an substantial impact on the system. It is said that identifying human reactions on weapon may let to describe gun movement and thus may be applied to weapon accuracy determination.

关键词： Rifle-shooter interaction Man-weapon forces Muzzle climb Firearm Recoil Accuracy

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