检索结果-南通市图书馆

Significance and prognostic value of lysosomal enzyme activities measured in surgically operated adenocarcinomas of the gastroesophageal junction and squamous cell carcinomas of the lower third of esophagus

引用

World Journal of Gastroenterology 2005年第37期11卷 5751-5756页

作者： Aron Altorjay Balazs Paal Nicolette Sohar janos kiss Imre Szanto Istvan Sohar Department of Surgery Saint George University Teaching Hospital Székesfehérvár Seregélyesi u. 3. H-8000 Hungary Center for Advanced Biotechnology and Medicine UMDNJ Piscataway NJ USA National Medical Center Department of Surgery Budapest Szabolcs u.33-35. H-1135 Hungary

AIM： To establish whether there are fundamental differences in the biochemistries of adenocarcinomas of the gastroesophageal junction （GEJ） and the squamous cell carcinomas of the lower third of the esophagus （LTE）. METHODS： Between February 1, 1997 and February 1, 2000, we obtained tissue samples at the moment of resection from 54 patients for biochemical analysis. The full set of data could be comprehensively analyzed in 47 of 54 patients＇ samples （81%）. Of these, 29 were adenocarcinomas of the GEJ Siewert type Ⅰ （n = 8）, type Ⅱ （n = 12）, type Ⅲ （n = 9）, and 18 presented as squamous cell carcinomas of the LTE. We evaluated the mean values of 11-lysosomal enzyme and 1-cytosol protease activities of the tumorous and surrounding mucosae as well as their relative activities, measured as the ratio of activity in tumor and normal tissues from the same patient. These data were further analyzed to establish the correlation with tumor localization, TNM stage （lymph-node involvement）, histological type （papillary, signet-ring cell, tubular）, state of differentiation （good, moderate, poor）, and survival （≤24 or ≥24 mo）. RESULTS： In adenocarcinomas, the activity of α-mannosidase （AMAN）, cathepsin B （CB） and dipeptidyl-peptidase Ⅰ （DPP Ⅰ） increased significantly as compared to the normal gastric mucosa. In squamous cell carcinomas of the esophagus, we also found a significant difference in the activity of cathepsin L and tripeptidyl-peptidase Ⅰ in addition to these three. There was a statistical correlation of AMAN, CB, and DPP Ⅰ activity between the level of differentiation of adenocarcinomas of the GEJ and lymph node involvement,because tumors with no lymph node metastases histologically confirmed as well-differentiated, showed a significantly lower activity. The differences in CB and DPP Ⅰ activity correlated well with the differences in survival rates, since the CB and DPP Ⅰ values of those who died within 24 mo following surgical intervention were significantly higher tha

关键词： Prognostic value Lysosomal enzymes Cardiac adenocarcinomas Siewert classification Esophageal squamous cell carcinoma

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

应用“A”型外展支具治疗股骨头缺血性坏死疗效分析

引用

中国矫形外科杂志 2014年第7期22卷 593-593页

作者：刘双张立军 Sandor kiss Tamas Terebessy Gyorgy Szoke janos kiss Imre Antal Miklos Szendroi 沈阳中国医科大学附属盛京医院沈阳中国医科大学附属盛京医院儿童骨科

股骨头缺血性坏死的最佳治疗方法一直存在争议。包容治疗和手术包容治疗各有利弊。近期多中心的研究结果显示对于中度的股骨头缺血性坏死病变采用股骨或骨盆截骨术其结果优于未手术的患者。但对于大龄和严重的股骨头坏死病例，其结果并... 详细信息

股骨头缺血性坏死的最佳治疗方法一直存在争议。包容治疗和手术包容治疗各有利弊。近期多中心的研究结果显示对于中度的股骨头缺血性坏死病变采用股骨或骨盆截骨术其结果优于未手术的患者。但对于大龄和严重的股骨头坏死病例，其结果并不理想。

关键词：股骨头缺血性坏死外展支具治疗疗效分析应用骨盆截骨术股骨头坏死治疗方法手术包

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

保留骨骺的胫骨近端恶性肿瘤切除术

引用

中国矫形外科杂志 2013年第11期21卷 1110-1110页

作者：徐佳康庆林 Sandor kiss Tamas Terebessy Gyorgy Szoke janos kiss Imre Antal Miklos Szendroi

本研究以5位患有胫骨恶性肿瘤的患者为研究对象，评估保留胫骨近端骨骺切除肿瘤的手术治疗方法。在5位患者中，3位为尤文氏肉瘤，2位患有骨肉瘤。4位患者近端切除平面与生长板平齐，1位患者则位于生长板下2cm。远端切除平面根据肿瘤边... 详细信息

本研究以5位患有胫骨恶性肿瘤的患者为研究对象，评估保留胫骨近端骨骺切除肿瘤的手术治疗方法。在5位患者中，3位为尤文氏肉瘤，2位患有骨肉瘤。4位患者近端切除平面与生长板平齐，1位患者则位于生长板下2cm。远端切除平面根据肿瘤边界不同而不同，且均位于骨干部位。切除的胫骨部分用同侧及对侧的腓骨来代替。2根腓骨的近端均被固定于骨骺中，来自对侧的移植腓骨远端则被固定于胫骨骨干中。下肢以Ilizarov支架进行固定。

关键词：恶性肿瘤切除术胫骨近端骨骺 Ilizarov 骨恶性肿瘤尤文氏肉瘤治疗方法胫骨骨干

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Improved Culture Media for Embryogenic Callus Generation in Sorghum [Sorghum bicolor (L.) Moench]

引用

Phyton-International Journal of Experimental Botany 2020年第1期89卷 111-119页

作者： Paul Chege Andrea Palagyi Csaba Lantos Erzsebet kiss janos Pauk Szent Istvan University Doctoral School of Plant ScienceGodolloPater K.u.1.H-2103Hungary Cereal Research Non-profit Ltd. Department of BiotechnologySzegedAlsokikotosor 9.H-6701Hungary

Many attempts on optimization of sorghum[Sorghum bicolor(L.)Moench]tissue culture induction media have been made,but the culture system remains with some bottlenecks compared to that of other *** study aimed at assessing the suitability of various induction media to produce embryogenic callus(yellow and friable)with high induction rates and reduced phenolic *** six culture medium modifications:3 based on Murashige and Skoog(MS)medium and one each based on Chu N6,Gamborg B5 and 190-2 media respectively were applied in the culture of mature embryos from 10 sorghum *** there was a genotype influence on the attainment of a yellow callus,friability of the callus was determined to be dependent on the culture medium and not the *** strength MS medium with 0.2 mg/l 2,4-D with 2.8 g/l Gelrite®as the gelling agent modified with 1.0 g/l KH_(2)PO_(4),1.0 g/l L-proline,1.0 g/l L-asparagine and 0.16 mg/l CuSO_(4)·5H_(2)O(type E)was found to be the most effective resulting in about 60%yellow coloured callus induction with 25%*** of CuSO_(4)·5H_(2)O,KH_(2)PO_(4),L-proline and L-asparagine significantly reduced the phenolic *** strength MS medium was observed to contribute to quality callus production when compared to full strength MS media modified with the *** half strength MS medium was also observed to suppress phenolic *** 190-2 produced the highest regeneration frequency(40%)among the 3-regeneration media *** results provide information on a suitable sorghum callus induction medium necessary for embryogenesis.

关键词： Sorghum medium embryogenic callus half-strength MS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A remark on density theorems for Riemann's zeta-function

引用

Science China Mathematics 2023年第12期66卷 2795-2802页

作者： janos Pintz ELKH Alfréd Rényi Mathematical Institute Budapest H-1053Hungary

The goal of this paper is to give a relatively simple proof of some known zero density estimates for Riemann's zeta-function which are sufficiently strong to break the density hypothesis for Re s>7/*** from a simple but ingenious idea of Halász the proof uses only classical knowledge about the zeta-function,results known for at least hundred years.

关键词： Riemann's zeta-function density hypothesis density theorems

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Semi-stable Extensions Over 1-dimensional Bases

引用

Acta Mathematica Sinica,English Series 2018年第1期34卷 103-113页

作者： janos KOLLAR Johannes NICAISE Chen Yang XU Department of Mathematics Princeton University Department of Mathematics Imperial CollegeSouth Kensington Campus Beijing International Center of Mathematics Research

Given a family of Calabi-Yau varieties over the punctured disc or over the field of Laurentseries, we show that, after a finite base change, the family can be extended across the origin while keeping the canonical class trivial. More generally, we prove similar extension results for families whose log-canonical class is semi-ample. We use these to show that the Berkovich and essential skeleta agree for smooth varieties over C（（t）） with semi-ample canonical class.

关键词： Semi-stable extension Laurent series essential skeleton

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Rheology of rock salt for salt tectonics modeling

引用

Petroleum Science 2016年第4期13卷 712-724页

作者： Shi-Yuan Li janos L.Urai School of Petroleum Engineering China University of PetroleumBeijing Endogene Dynamik Faculty of Geo-Resources and Materials Technology RWTH Aachen University

Numerical modeling of salt tectonics is a rapidly evolving field; however, the constitutive equations to model long-term rock salt rheology in nature still remain controversial. Firstly, we built a database about the strain rate versus the differential stress through collecting the data from salt creep experiments at a range of temperatures（20–200 ℃） in laboratories. The aim is to collect data about salt deformation in nature, and the flow properties can be extracted from the data in laboratory ***, as an important preparation for salt tectonics modeling, a numerical model based on creep experiments of rock salt was developed in order to verify the specific model using the Abaqus package. Finally, under the condition of low differential stresses, the deformation mechanism would be extrapolated and discussed according to microstructure research. Since the studies of salt deformation in nature are the reliable extrapolation of laboratory data, we simplified the rock salt rheology to dislocation creep corresponding to power law creep（n = 5） with the appropriate material parameters in the salt tectonic modeling.

关键词： Rock salt rheology Power law creep Dislocation creep Modeling

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

ENGINEERING CHARACTERIZATION OF STRENGTH AND ELASTIC PROPERTIES OF GEOPOLYMER CEMENT CONCRETE MATERIALS

引用

Journal of Green Building 2015年第4期10卷 89-106页

作者： Brett Tempest janos Gergely C.Weggel the University of North Carolina at Charlotte

Geopolymer cements provide an alternative to the Portland cement used to produce structural *** this study,geopolymer cements were used to create concrete having compressive strength in the range of 34 to 83 MPa(5,000-12,000 psi).The mechanical properties of these concrete materials were evaluated to determine the compressive and tensile strengths and immediate and long term elastic *** geopolymer cement concrete(GCC)was found to perform in a similar manner to Portland cement concrete(PCC).Long term shrinkage and creep properties of GCC materials were found to be lower than the values typical for PCC.

关键词： geopolymer shrinkage creep elastic modulus stress-strain modulus of rupture

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A case of interstitial pneumonitis in a patient with ulcerative colitis treated with azathioprine

引用

World Journal of Gastroenterology 2007年第2期13卷 316-319页

作者： Ferenc Nagy Tamas Molnar Eva Makula Ildiko kiss Peter Milassin Eva Zollei Laszlo Tiszlavicz janos Lonovics First Department of Medicine University of Szeged Faculty of Medicine Szeged Hungary Department of Radiology University of Szeged Faculty of Medicine Szeged Hungary Medical Intensive Care Unit University of Szeged Faculty of Medicine Szeged Hungary Institute of Pathology University of Szeged Faculty of Medicine Szeged Hungary

The early hypersensitivity reaction and late bone marrow depression are well-known side-effects of azathioprine, whereas interstitial pneumonia is a rare complication. A 40-year old male patient had been treated with azathioprine in consequence of extensive ulcerative colitis for 10 years. He then complained of 7 d of fever, cough and catarrhal signs, without symptoms of active colitis. Opportunistic infections were ruled out. The chest X-ray, CT and lung biopsy demonstrated the presence of interstitial inflammation. Azathioprine therapy was discontinued as a potential source of the pulmonary infiltrate. In response to steroid therapy, and intensive care, the pulmonary infiltrate gradually decreased within 4 wk. Three months later, his ulcerative colitis relapsed, and ileo-anal pouch surgery was performed. In cases of atypical pneumonia, without a proven infection, azathioprine-associated interstitial pneumonitis may be present, which heals after withdrawal of the drug.

关键词： Inflammatory bowel disease Ulcerative colitis Azathioprine Interstitial pneumonitis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tilted pulse front pumping techniques for efficient terahertz pulse generation

引用

Light(Science & Applications) 2023年第11期12卷 2291-2308页

作者： Gyorgy Toth Gyula Polonyi janos Hebling University of Pecs Pecs 7624Hungary Szentagothai Research Centre Pecs 7624Hungary HUN-REN-PTE High-Field Terahertz Research Group Pecs 7624Hungary

Optical rectification of femtosecond laser pulses has emerged as the dominant technique for generating single-and few-cycle terahertz(THz)*** advent of the tilted pulse front pumping(TPFP)velocity matching technique,proposed and implemented two decades ago,has ushered in significant advancements of these THz sources,which are pivotal in the realm of THz pump-probe and material control experiments,which need THz pulses with microjoule energies and several hundred kV/cm electric field ***,these THz sources are poised to play a crucial role in the realization of THz-driven particle accelerators,necessitating millijoule-level pulses with tens of MV/cm electric field *** has enabled the efficient velocity matching in lithium niobate crystals renowned for their extraordinary high nonlinear ***,its adaptation to semiconductor THz sources has resulted in a two-hundred-times enhancement in conversion *** this comprehensive review,we present the seminal achievements of the past two *** expound on the conventional TPFP setup,delineate its scaling limits,and elucidate the novel generation TPFP configurations proposed to surmount these constraints,accompanied by their preliminary ***,we provide an in-depth analysis of the THz absorption,refractive index,and nonlinear coefficient spectra of lithium niobate and widely used semiconductors employed as THz generators,which dictate their suitability as THz *** underscore the far-reaching advantages of tilted pulse front pumping,not only for LN and semiconductor-based THz sources but also for selected organic crystal-based sources and Yb-laserpumped GaP sources,previously regarded as velocity-matched in the literature.

关键词： pumping pulse realization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：