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Tilted pulse front pumping techniques for efficient terahertz pulse generation

Light(Science & Applications) 2023年第11期12卷 2291-2308页

作者： Gyorgy Toth Gyula Polonyi janos hebling University of Pecs Pecs 7624Hungary Szentagothai Research Centre Pecs 7624Hungary HUN-REN-PTE High-Field Terahertz Research Group Pecs 7624Hungary

Optical rectification of femtosecond laser pulses has emerged as the dominant technique for generating single-and few-cycle terahertz(THz)*** advent of the tilted pulse front pumping(TPFP)velocity matching technique,proposed and implemented two decades ago,has ushered in significant advancements of these THz sources,which are pivotal in the realm of THz pump-probe and material control experiments,which need THz pulses with microjoule energies and several hundred kV/cm electric field ***,these THz sources are poised to play a crucial role in the realization of THz-driven particle accelerators,necessitating millijoule-level pulses with tens of MV/cm electric field *** has enabled the efficient velocity matching in lithium niobate crystals renowned for their extraordinary high nonlinear ***,its adaptation to semiconductor THz sources has resulted in a two-hundred-times enhancement in conversion *** this comprehensive review,we present the seminal achievements of the past two *** expound on the conventional TPFP setup,delineate its scaling limits,and elucidate the novel generation TPFP configurations proposed to surmount these constraints,accompanied by their preliminary ***,we provide an in-depth analysis of the THz absorption,refractive index,and nonlinear coefficient spectra of lithium niobate and widely used semiconductors employed as THz generators,which dictate their suitability as THz *** underscore the far-reaching advantages of tilted pulse front pumping,not only for LN and semiconductor-based THz sources but also for selected organic crystal-based sources and Yb-laserpumped GaP sources,previously regarded as velocity-matched in the literature.

关键词： pumping pulse realization

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A remark on density theorems for Riemann's zeta-function

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Science China Mathematics 2023年第12期66卷 2795-2802页

作者： janos Pintz ELKH Alfréd Rényi Mathematical Institute Budapest H-1053Hungary

The goal of this paper is to give a relatively simple proof of some known zero density estimates for Riemann's zeta-function which are sufficiently strong to break the density hypothesis for Re s>7/*** from a simple but ingenious idea of Halász the proof uses only classical knowledge about the zeta-function,results known for at least hundred years.

关键词： Riemann's zeta-function density hypothesis density theorems

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Prolonged intestinal mucosal acidosis is associated with multiple organ failure in human acute pancreatitis: Gastric tonometry revisited

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World Journal of Gastroenterology 2006年第30期12卷 4892-4896页

作者： Gabor C Kovacs Geza Telek janos Hamar Jozsef Furesz janos Regoly-Merei 3rd Department of Surgery Semmelweis University Budapest Hungary Department of Experimental Research National Institute of Traumatology Budapest Hungary Institute of Health Protection Hungarian Defense Forces Budapest Hungary

AIM： To evaluate whether multiple determinations of intramucosal pH （pHi） in acute pancreatitis （AP） patients could provide additional information of the disease severity during early hospitalization. METHODS： Twenty-one patients suffering from acute pancreatitis were monitored by gastric tonometry in the first 72 h after hospital admission. RESULTS： In the survivor group （n = 15） the initially low phi values returned to normal level （pHi ≥ 7.32） within 48 h （median pHi： d 1： 7.21; d 2： 7.32; d 3： 7.33）. In contrast, pHi values in the non-survivor group n = 6） were persistently either below or in the low normal range （median pHi 7.12; 7.12; 7.07 respectively）, but pHi differences between the two groups reached significance only after 24 h （P 〈 0.01）. Mucosal acidosis detected at any time during the monitored period was associated with the emergence of single or multiple organ dysfunction （P 〈 0.01）. CONCLUSION： Prolonged gastric mucosal acidosis was associated with remote organ dysfunction and failure in Acute Pancreatitis, however, correlation with the fatal outcome became significant only 24 h after admission. Due to its non-invasive nature gastric tonometry may supplement the pro-inflammatory markers to achieve a multi-faceted monitoring of the disease.

关键词： Acute pancreatitis Human studies Intramucosal pH Mucosal barrier dysfunction Septic complications Bacterial translocation Multiple organ dysfunction

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Double balloon enteroscopy examinations in general anesthesia

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World Journal of Gastroenterology 2010年第27期16卷 3418-3422页

作者： Laszlo Zubek Lena Szabo Peter Laszlo Lakatos janos Papp janos Gal Gabor Elo Department of Anaesthesiology and Intensive Therapy Semmelweis University 2nd Department of Pediatrics Semmelweis University 1st Department of Medicine Semmelweis University

AIM:To demonstrate that the double balloon enteroscopy(DBE) can be safely performed in general anesthesia with ***:We performed a retrospective examination between August 2005 and November 2008 amongpatients receiving intubation narcosis due to DBE *** patients were grouped based on sex,age and physical *** records includedduration of anesthesia,quantity of medication usedand anesthesia-related *** determinedthe frequency of complications in the different groupsand their relation with the quantity of medication usedand the duration of ***:We compiled data for 108 cases of general anesthesia with *** did not observeany permanent anesthesia-related complications;themost frequent side effects of anesthesia were hypo-tension(30.55%),desaturation(21.29%),and apnea(17.59%).These complications were significantly more frequent among patients with multiple additional diseases [hypotension(23.1% vs 76.9%,P = 0.005),desaturation(12.3% vs 69.2%,P < 0.001) and apnea(7.7% vs 53.8%,P = 0.001)],however,their incidence was not proportional to the quantity of medication used or the duration of ***:General anesthesia with intubation is definitely a viable option among DBE *** is highly recommended in patients with multiple additional diseases.

关键词： Double balloon enteroscopy General anesthesia Intubation Sedation Patient autonomy

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Semi-stable Extensions Over 1-dimensional Bases

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Acta Mathematica Sinica,English Series 2018年第1期34卷 103-113页

作者： janos KOLLAR Johannes NICAISE Chen Yang XU Department of Mathematics Princeton University Department of Mathematics Imperial CollegeSouth Kensington Campus Beijing International Center of Mathematics Research

Given a family of Calabi-Yau varieties over the punctured disc or over the field of Laurentseries, we show that, after a finite base change, the family can be extended across the origin while keeping the canonical class trivial. More generally, we prove similar extension results for families whose log-canonical class is semi-ample. We use these to show that the Berkovich and essential skeleta agree for smooth varieties over C（（t）） with semi-ample canonical class.

关键词： Semi-stable extension Laurent series essential skeleton

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Germline MLH1 and MSH2 mutational spectrum including frequent large genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families:Implications for genetic testing

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World Journal of Gastroenterology 2007年第19期13卷 2727-2732页

作者： janos Papp Marietta E Kovacs Edith Olah Department of Molecular Genetics National Institute of Oncology Rath Gy. u. 7-9 H-1122 Budapest Hungary

AIM: To analyze the prevalence of germline MLH1 and MSH2 gene mutations and evaluate the clinical characteristics of Hungarian hereditary non-polyposis colorectal cancer (HNPCC) families. METHODS: Thirty-six kindreds were tested for mutations using conformation sensitive gel electrophoreses, direct sequencing and also screening for genomic rearrangements applying multiplex ligation-dependent probe amplifi cation (MLPA). RESULTS: Eighteen germline mutations (50%) were identifi ed, 9 in MLH1 and 9 in MSH2. Sixteen of these sequence alterations were considered pathogenic, the remaining two were non-conservative missense alterations occurring at highly conserved functional motifs. The majority of the defi nite pathogenic mutations (81%, 13/16) were found in families fulfilling the stringent Amsterdam Ⅰ/Ⅱ criteria, including three rearrangements revealed by MLPA (two in MSH2 and one in MLH1). However, in three out of sixteen HNPCC-suspected families (19%), a disease-causing alteration could be revealed. Furthermore, nine mutations described here are novel, and none of the sequence changes were found in more than one ***: Our study describes for the f irst time the prevalence and spectrum of germline mismatch repair gene mutations in Hungarian HNPCC and suspected-HNPCC families. The results presented here suggest that clinical selection criteria should be relaxed and detection of genomic rearrangements should be included in genetic screening in this population.

关键词： Germline mutation Hereditary non-polyposis colorectal cancer MLH1 MSH2 Rearrangement

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Rheology of rock salt for salt tectonics modeling

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Petroleum Science 2016年第4期13卷 712-724页

作者： Shi-Yuan Li janos L.Urai School of Petroleum Engineering China University of PetroleumBeijing Endogene Dynamik Faculty of Geo-Resources and Materials Technology RWTH Aachen University

Numerical modeling of salt tectonics is a rapidly evolving field; however, the constitutive equations to model long-term rock salt rheology in nature still remain controversial. Firstly, we built a database about the strain rate versus the differential stress through collecting the data from salt creep experiments at a range of temperatures（20–200 ℃） in laboratories. The aim is to collect data about salt deformation in nature, and the flow properties can be extracted from the data in laboratory ***, as an important preparation for salt tectonics modeling, a numerical model based on creep experiments of rock salt was developed in order to verify the specific model using the Abaqus package. Finally, under the condition of low differential stresses, the deformation mechanism would be extrapolated and discussed according to microstructure research. Since the studies of salt deformation in nature are the reliable extrapolation of laboratory data, we simplified the rock salt rheology to dislocation creep corresponding to power law creep（n = 5） with the appropriate material parameters in the salt tectonic modeling.

关键词： Rock salt rheology Power law creep Dislocation creep Modeling

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ENGINEERING CHARACTERIZATION OF STRENGTH AND ELASTIC PROPERTIES OF GEOPOLYMER CEMENT CONCRETE MATERIALS

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Journal of Green Building 2015年第4期10卷 89-106页

作者： Brett Tempest janos Gergely C.Weggel the University of North Carolina at Charlotte

Geopolymer cements provide an alternative to the Portland cement used to produce structural *** this study,geopolymer cements were used to create concrete having compressive strength in the range of 34 to 83 MPa(5,000-12,000 psi).The mechanical properties of these concrete materials were evaluated to determine the compressive and tensile strengths and immediate and long term elastic *** geopolymer cement concrete(GCC)was found to perform in a similar manner to Portland cement concrete(PCC).Long term shrinkage and creep properties of GCC materials were found to be lower than the values typical for PCC.

关键词： geopolymer shrinkage creep elastic modulus stress-strain modulus of rupture

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Catalytic behavior in propane aromatization using GA-MFI catalyst

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Chinese Journal of Chemical Engineering 2017年第12期25卷 1863-1870页

作者： Alfredo Aloise Enrico Catizzone Massimo Migliori janos B.Nagy Girolamo Giordano University of Calabria Department of Environmental and Chemical Engineering Via P. Bucci 1-87036 Rende CS Italy

Ga-Al-MFI samples were synthesized in hydrothermal conditions from gels of composition 1.08CH3NH2- 0.134TPABr-1SiO2-xAl2O3-yGa2O3-40H2O at 175 ℃ for 7 days, with x = 0.005 and 0.0025, y = 0.005, 0,010 and 0.020. The samples were characterized by XRD, BET measurements, thermal analysis （TGA-DTA） atomic absorption and high resolution solid state MAS 27Al and 71Ga NMR measurements. The aromatization of propane was studied as catalytic test. The activity and selectivity of the catalysts were determined for benzene, toluene and xylenes on the one hand and for methane and ethane on the other hand. The most active sample was obtained with the highest Ga/AI ratio. For this sample, the BTX selectivity obtained by aromatization was always higher than the hydrocracking selectivity leading to methane and ethane. The relative amount of toluene was higher than that of benzene and ofxylenes. The samples were deactivated by coke formation that was revealed more severe for the most active sample,

关键词： Propane aromatization Gallium ZSM-5 Coke formation Catalyst deactivation

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Perianal disease,small bowel disease,smoking,prior steroid or early azathioprine/biological therapy are predictors of disease behavior change in patients with Crohn's disease

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World Journal of Gastroenterology 2009年第28期15卷 3504-3510页

作者： Peter Laszlo Lakatos Zsofia Czegledi Tamas Szamosi janos Banai Gyula David Ferenc Zsigmond Tunde Pandur Zsuzsanna Erdelyi Orsolya Gemela janos Papp Laszlo Lakatos 1st Department of Medicine Semmelweis University H-1083 Budapest Hungary Department of Gastroenterology State Health Center H-1062 Budapest Hungary 1st Department of Medicine Csolnoky F. County Hospital HH8201-Veszprem Hungary

AIM:To assess the combined effect of disease phenotype, smoking and medical therapy [steroid, azathioprine(AZA), AZA/biological therapy] on the probability of disease behavior change in a Caucasian cohort of patients with Crohn's disease(CD).METHODS:Three hundred and forty well-characterized, unrelated, consecutive CD patients were analyzed(M/F:155/185, duration:9.4 ± 7.5 years) with a complete clinical *** records including disease phenotype according to the Montreal classification, extraintestinal manifestations, use of medications and surgical events were analyzed *** were interviewed on their smoking habits at the time of diagnosis and during the regular follow-up ***:A change in disease behavior was observed in 30.8% of patients with an initially non-stricturing, non-penetrating disease behavior after a mean diseaseduration of 9.0 ± 7.2 *** a logistic regression analysis corrected for disease duration, perianal disease, smoking, steroid use, early AZA or AZA/ biological therapy use were independent predictors of disease behavior *** a subsequent Kaplan-Meier survival analysis and a proportional Cox regression analysis, disease location(P = 0.001), presence of perianal disease(P < 0.001), prior steroid use(P = 0.006), early AZA(P = 0.005) or AZA/biological therapy(P = 0.002), or smoking(P = 0.032) were independent predictors of disease behavior ***:Our data suggest that perianal disease, small bowel disease, smoking, prior steroid use, early AZA or AZA/biological therapy are all predictors of disease behavior change in CD patients.

关键词： Crohn's disease Smoking Azathioprine Infliximab Monoclonal antibodies Colectomy Risk Reoperation

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