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Concurrence of high dust aerosol and stratosphere-intruded ozone pollution in super sandstorms

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Science Bulletin 2024年第16期69卷 2509-2513页

作者： Zhixiong Chen jane Liu Xiushu Qie Xugeng Cheng mengmiao Yang Lei Shu Jing m.Chen Key Laboratory for Humid Subtropical Eco-Geographical Processes of the ministry of Education School of Geographical SciencesFujian Normal UniversityFuzhou 350117China Key Laboratory of Atmospheric Environment and Extreme meteorology Chinese Academy of SciencesBeijing 100029China Department of Geography and Planning University of TorontoToronto M5S 3G3Canada Key Laboratory of middle Atmosphere and Global Environment Observation(LAGEO) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Science University of Chinese Academy of SciencesBeijing 100049China

The air quality in China has substantially improved in recent years,as indicated by the declining trends in SO_(2),NO_(2),Pm_(2.5)and Pm_(10)*** the reduced anthropogenic pollutant emissions;however,sustained increases in surface ozone(O_(3))that may impair the effectiveness of clean air actions have been ***,complex heavy pollution episodes can still occur,and some of these episodes are closely linked with *** example,two severe sandstorms occurred successively in the early spring of 2021 in North China,despite the sandstorm frequency in China having significantly decreased in recent years[1-3].

关键词： ozone sands aerosol

微柱HPLC用的简单在线光导纤维UV检测器

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国外分析仪器技术与应用 1989年第4期 86-87页

作者： jane.,m 傅若农

Analysis of the Driving Force of Hydrodynamics in Lake Naivasha, Kenya

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Open Journal of modern Hydrology 2015年第4期5卷 95-104页

作者： jane N. Ndungu Wenlong Chen Denie C. m. Augustijn Suzanne J. m. H. Hulscher mEEP Kenya Marine and Fisheries Research Institute Mombasa Kenya Twente Water Centre University of Twente Enschede The Netherlands

The hydrodynamics in Lake Naivasha, a shallow endorheic lake, are simulated using the Delft3D Flow module to investigate the major driving forces of hydrodynamics in the lake. The results showed wind as the major forcing. The shallow zones of the lake showed currents movement in the same direction as the wind while the deep zones showed currents movements against the wind direction. These findings were confirmed and further explained using an idealized model. Limited exchange between the Crescent Lake (crater lake which is temporally separated from the lake during low water levels) and the main lake was observed. These findings can explain the spatial variability of the water quality in the lake. Similar studies could be used in exploratory studies of the spatial-temporal variability in water quality in other shallow water systems.

关键词： Hydrodynamics Water Quality Shallow Lakes Wind-Driven Currents Lake Naivasha

基于文献计量的中外人工智能政策研究现状及启示

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情报杂志 2021年第1期40卷 48-55页

作者：郑烨任牡丹 jane E.Fountain 西北工业大学人文与经法学院西安710072 麻省大学安默斯特分校国家数字政府研究中心安默斯特01003

[目的/意义]人工智能已成为推动新一轮科技革命和产业变革的重要技术力量,世界各国加紧出台了相关政策。通过对当前研究进行及时梳理,可为今后国内人工智能政策的理论推进及政策出台和完善等提供指导。[方法/过程]以国外SSCI和国内CSSC... 详细信息

[目的/意义]人工智能已成为推动新一轮科技革命和产业变革的重要技术力量,世界各国加紧出台了相关政策。通过对当前研究进行及时梳理,可为今后国内人工智能政策的理论推进及政策出台和完善等提供指导。[方法/过程]以国外SSCI和国内CSSCI期刊数据库收录的395篇研究论文为样本,采用文献计量分析和比较研究法对中外人工智能政策研究的高共被引文献、热点主题及演进趋势等进行深入探索。[结果/结论]与国外相比,国内研究起步较晚但势头迅猛;高共被引文献反映了人工智能领域存在的问题和风险、应用前景、技术革新及对社会的影响;国外研究热点涵盖了知识管理等十二类主题,而国内研究热点则包括国家治理背景下人工智能政策发展路径等三类主题;国外研究的演进特征体现在三个方面,而国内研究则体现在两个方面。最后,从加快形成和构建人工智能政策研究的理论框架体系等三个方面提出对国内研究的启示。

关键词：人工智能人工智能政策高共被引文献研究主题演进趋势

水稻受稻瘟病菌侵染后过氧化物酶定位的超微观察

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中国水稻科学 2002年第1期16卷 57-62页

作者：杨民和郑重 jane.LEACH 浙江大学农业与生物技术学院植物保护系江西农业大学农学院江西南昌330045 堪萨斯州立大学

利用联苯胺蓝 (3,3'- diaminobenzidine,DAB)染色法原位检测了水稻 -稻瘟病菌互作过程中 H2 O2 和过氧化物酶被诱导产生和积累的过程。结果表明在病原菌接种后 ,水稻叶鞘内表皮细胞在伤口、气孔保卫细胞及病菌侵染点等 3种情况下可以检... 详细信息

利用联苯胺蓝 (3,3'- diaminobenzidine,DAB)染色法原位检测了水稻 -稻瘟病菌互作过程中 H2 O2 和过氧化物酶被诱导产生和积累的过程。结果表明在病原菌接种后 ,水稻叶鞘内表皮细胞在伤口、气孔保卫细胞及病菌侵染点等 3种情况下可以检测到染色反应。在水稻 -稻瘟病菌非亲和性互作中 ,H2 O2 产生和过氧化物酶活性上升快 ,并逐渐积累到较高的水平 ;而在亲和性互作反应中 ,H2 O2 产生和过氧化物酶活性上升被延迟 ,积累水平较低。超微结构研究表明 ,在非亲和性互作反应中 ,过氧化物酶主要定位于被侵染寄主细胞的细胞壁、细胞质、细胞膜、侵染菌丝周围及由膜系统构成的囊泡膜上 ;而在亲和性互作反应中 ,早期 (接种后 16 h)几乎难以观察到过氧化物酶的聚集 ,后期 (接种后 30 h)过氧化物酶聚集增多 ,但仍明显低于非亲和性互作反应。

关键词：稻瘟病过氧化氢过氧化物酶细胞化学超微结构定位研究

method to assess component contribution to toxicity of complex mixtures： Assessment of puberty acquisition in rats exposed to disinfection byproducts

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Journal of Environmental Sciences 2017年第8期29卷 311-321页

作者： Shahid Parvez Glenn E.Rice Linda K.Teuschler jane Ellen Simmons Thomas F.Speth Susan D.Richardson Richard J.miltner E.Sidney Hunter Ⅲ Jonathan G.Pressman Lillian F.Strader Gary R.Klinefelter Jerome m.Goldman michael G.Narotsky Indiana University Richard m. Fairbanks School of Public Health Department of Environmental Health Sciences IUPUI Campus Indianapolis IN 46202 USA National Center for Environmental Assessment Office of Research and Development U.S. Environmental Protection Agency Cincinnati OH 45268 USA Lincla Teuschler and Associates St. Petersburg FL 33707 USA National Health and Environmental Effects Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Research Triangle Park NC 27711 USA National Risk management Research Laboratory Office of Research and Development U.S. Environmental Protection Agency Cincinnati OH 45268 USA Department of Chemistry and Biochemistry University of South Carolina Columbia SC 29208 USA

A method based on regression modeling was developed to discern the contribution of component chemicals to the toxicity of highly complex, environmentally realistic mixtures of disinfection byproducts（DBPs）. Chemical disinfection of drinking water forms DBP *** of concerns about possible reproductive and developmental toxicity, a whole mixture（Wm） of DBPs produced by chlorination of a water concentrate was administered as drinking water to Sprague–Dawley（S–D） rats in a multigenerational study. Age of puberty acquisition,i.e., preputial separation（PPS） and vaginal opening（VO）, was examined in male and female offspring, respectively. When compared to controls, a slight, but statistically significant delay in puberty acquisition was observed in females but not in males. Wm-induced differences in the age at puberty acquisition were compared to those reported in S–D rats administered either a defined mixture（Dm） of nine regulated DBPs or individual DBPs. Regression models were developed using individual animal data on age at PPS or VO from the Dm study. Puberty acquisition data reported in the Wm and individual DBP studies were then compared with the Dm models. The delay in puberty acquisition observed in the Wm-treated female rats could not be distinguished from delays predicted by the Dm regression model, suggesting that the nine regulated DBPs in the Dm might account for much of the delay observed in the Wm. This method is applicable to mixtures of other types of chemicals and other endpoints.

关键词： Drinking water disinfection byproducts DBP Puberty delay Four Lab Study mixtures risk assessment

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翻译产业正成为新兴产业

空中英语教室（高级版．彭蒙惠英语） 2011年第10期 30-31,46页

作者： jane m. Von Bergen

语言服务正成为一个快速成长变化的领域再过不到3周就会完成硕士学位的戴尔·艾格特在找工作方面一点也没问题，他将在毕业之后的那周开始上班。

关键词：新兴产业翻译产业快速成长语言服务硕士学位艾格戴尔

Leptin rescues neurons from Alzheimer’s disease-related pathways triggered by lipid burden

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Advances in Alzheimer's Disease 2013年第1期2卷 31-39页

作者： Steven J. Greco George Perry J. Wesson Ashford Ashkan Hamzelou jane m. Johnston Nikolaos Tezapsidis Neurotez Inc. Bridgewater USA Stanford/VA medical Center Palo Alto USA University of Texas San Antonio USA

Adipocyte-derived leptin is a pleiotropic hormone implicated in control of lipid storage and mobilization, bone homeostasis, immune function and neuronal plasticity. Leptin has been shown to prevent accumulation of extracellular Aβ and hyperphosphorylation of tau in both cell culture and animal models. Herein an investigation was undertaken to test leptin’s ability to prevent the exacerbation/activation of AD-related pathways in neurons following their exposure to a high concentration of a variety of lipids. Specifically, cholesterol, oleic acid and/or ceramide were added to the media of cells resulting in decreased cellular viability and energy metabolism, and in increased tau phosphorylation and extracellular Aβ. Leptin increased viability, boosted cellular metabolism by activating AmP-activated protein kinase (AmPK) and the sirtuins (SIRT) and reduced tau phosphorylation and Aβ accumulation in a dose-dependent manner in response to select challenges. These findings demonstrate that leptin can attenuate the harmful effect of certain lipids that lead to exacerbation or activation of AD pathways. The study herein also provides the basis for a novel screening platform to define and identify a novel class of “metabolic” compounds addressing Alzheimer’s disease, based on a biological profile similar to leptin.

关键词： Leptin Cholesterol Ceramide AmPK SIRT Alzheimer’s Tau Amyloid-β

Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis

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Protein & Cell 2012年第12期3卷 934-942页

作者： Sheng-Lian Yang Erica Harnish Thomas Leeuw Uwe Dietz Erika Batchelder Paul SWright jane Peppard Paul August Cecile Volle-Challier Francoise Bono Jean-marc Herbert Juan Carlos Izpisua Belmonte Gene Expression Laboratories The Salk Institute for Biological Studies10010 N.Torrey Pines Rd.La JollaCA 92037USA Sanofi US R&DEarly to Candidate UnitTucson Research Center2090 E.Innovation Park DriveTucsonAZ 85755USA Sanofi Deutschland GmbH R&DTSU Aging Quality of LifeIndustriepark HoechstFrankfurt am Main 65926Germany Sanofi R&D Early to Candidate Unit195Route d'Espagne-BP 13669ToulouseFrance Center of Regeneration medicine Dr.Aiguader 88Barcelona 08003Spain

Articular cartilage,which is mainly composed of collagen Ⅱ,enables smooth skeletal *** of collagen Ⅱ can be caused by various events,such as injury,but degeneration especially increases over the course of normal ***,the body does not fully repair itself from this type of degeneration,resulting in impaired ***,an articular cartilage repair surgical technique,has been commonly used in the clinic to induce the repair of tissue at damage *** stem cells(mSC)have also been used as cell therapy to repair degenerated ***,the therapeutic outcomes of all these techniques vary in different patients depending on their age,health,lesion size and the extent of damage to the *** repairing tissues either form fibrocartilage or go into a hypertrophic stage,both of which do not reproduce the equivalent functionality of endogenous hyaline *** of the reasons for this is inefficient chondrogenesis by endogenous and exogenous *** that promote chondrogenesis could be used to induce self-repair of damaged cartilage as a non-invasive approach alone,or combined with other techniques to greatly assist the therapeutic *** recent development of human induced pluripotent stem cell(iPSCs),which are able to self-renew and differentiate into multiple cell types,provides a potentially valuable cell resource for drug screening in a“more relevant”cell *** we report a screening platform using human iPSCs in a multi-well plate format to identify compounds that could promote chondrogenesis.

关键词： hESC hiPSC chondrogenesis compound screening platform