检索结果-南通市图书馆

Does combined therapy of curcumin and epigallocatechin gallate have a synergistic neuroprotective effect against spinal cord injury？

引用

Neural Regeneration Research 2018年第1期13卷 119-127页

作者： Jiri Ruzicka Lucia Machova Urdzikova barbora Svobodova Anubhav G. Amin Kristyna Karova jana Dubisova Kristyna Zaviskova Sarka Kubinova Meic Schmidt Meena Jhanwar-Uniyal Pavla Jendelova Institute of Experimental Medicine Academy of Sciences of the Czech Republic Videfiska Prague Czech Republic Department of Neuroscience Charles University Second Faculty of Medicine Prague Czech Republic New York Medical College Valhalla NY USA

Systematic inflammatory response after spinal cord injury （SCI） is one of the factors leading to lesion development and a profound degree of functional loss. Anti-inflammatory compounds, such as curcumin and epigallocatechin gallate （EGCG） are known for their neuroprotective effects. In this study, we investigated the effect of combined therapy of curcumin and EGCG in a rat model of acute SCI induced by balloon compression. Immediately after SCI, rats received curcumin, EGCG, curcumin ＋ EGCG or saline [daily intraperitoneal doses （curcumin, 6 mg/kg; EGCG 17 mg/kg）] and weekly intramuscular doses （curcumin,60 mg/kg; EGCG 17 mg/kg）] for 28 days. Rats were evaluated using behavioral tests （the basso, beattie, and bresnahan （bbb） open-field locomotor test, flat beam test）. Spinal cord tissue was analyzed using histological methods （Luxol blue-cresyl violet staining） and mmunohistochemistry （anti-glial fibrillary acidic protein, anti-growth associated protein 43）. Cytokine levels （interleukin-1β, interleukin-4, interleukin-2,interleukin-6, macrophage inflammatory protein 1-alpha, and RANTES） were measured using Luminex assay. Quantitative polymerase chain reaction was performed to determine the relative expression of genes （Sort1, Fgf2, Irf5, Mrc1, Olig2, Casp3, Gap43, Gfap, Vegf, Nfκb, Cntf） related to regenerative processes in injured spinal cord. We found that all treatments displayed significant behavioral recovery, with no obvious synergistic effect after combined therapy of curcumin and ECGC. Curcumin and EGCG alone or in combination increased axonal sprouting, decreased glial scar formation, and altered the levels of macrophage inflammatory protein 1-alpha, interleukin-1β, interleukin-4 and interleukin-6 cytokines. These results imply that although the expected synergistic response of this combined therapy was less obvious, aspects of tissue regeneration and immune responses in severe SCI were evident.

关键词： spinal cord injury epigallocatechin gallate curcumin inflammatory response neural regeneration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart?A crystallographic,biophysical,and theoretical study

引用

hLife 2024年第8期2卷 419-433页

作者： Mohamed Ibrahim Xinyuanyuan Sun Vinicius Martins de Oliveira Ruibin Liu Joseph Clayton Haifa El Kilani jana Shen Rolf Hilgenfeld Institute of Molecular Medicine University of Lübeck23562 LübeckGermany Department of Pharmaceutical Sciences University of Maryland School of PharmacyBaltimoreMD 21201USA Division of Applied Regulatory Science Office of Clinical PharmacologyOffice of Translational SciencesCenter for Drug Evaluation and ResearchUnited States Food and Drug AdministrationSilver SpringMD 20993USA German Center for Infection Research(DZIF) Hamburg-Lübeck-Borstel-Riems SiteUniversity of Lübeck23562 LübeckGermany

During the continuing evolution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),the Omicron variant of concern emerged in the second half of 2021 and has been dominant since November of that *** with its sublineages,it has maintained a prominent role ever *** Nsp5 main protease(Mpro)of the Omicron virus is characterized by a single dominant mutation,*** we determined the X-ray crystal structures of the P132H mutant(or O-Mpro)as a free enzyme and in complex with the Mpro inhibitor,the alpha-ketoamide 13b-K,and we conducted enzymological,biophysical,as well as theoretical studies to characterize the *** found that O-Mpro has a similar overall structure and binding with 13b-K;however,it displays lower enzymatic activity and lower thermal stability compared to the WT-Mpro(with“WT”referring to the prototype strain).Intriguingly,the imidazole ring of His132 and the carboxylate plane of Glu240 are in a stacked configuration in the X-ray structures determined *** folding free energy calculations suggest that the O-Mpro dimer is destabilized relative to the WT-Mpro due to less favorable van der Waals interactions and backbone conformations in the individual ***-atom continuous constant-pH molecular dynamics(MD)simulations reveal that His132 and Glu240 display coupled *** pH 7,His132 is predominantly neutral and in a stacked configuration with respect to Glu240 which is *** order to examine whether the Omicron mutation eases the emergence of further Mpro mutations,we also analyzed the P132H+T169S double mutant,which is characteristic of the bA.1.1.2 ***,we found little evidence of a correlation between the two mutation sites.

关键词： severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) main protease Omicron molecular dynamics Pro>His mutant double mutant

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genetic analysis for geographic isolation comparison of brown bears living in the periphery of the Western Carpathians Mountains with bears living in other areas

引用

Open Journal of Genetics 2013年第3期3卷 174-182页

作者： Jan Graban jana Kiskova Pavol Pepich Robin Rigg Institute of the High Mountain biology University of Zilina Tatranska JavorinaTatranska JavorinaSlovak Republic Institute of Foreign Languages University of ZilinaZilinaSlovak Republic Slovak Wildlife Society Liptovsky HradokSlovak Republic

Populations of the European brown bear (Ursus arctos L.) differ substantially in size, degree of geographic isolation and level of genetic diversity. Present patterns result from phylogeographic processes and profound human intervention. We assessed the genetic variability of a subpopulation of brown bears near the periphery of their range in the Western Carpathian Mountains and compared their genetic properties with those of bears in the core of the same population and elsewhere. Samples were collected non-invasively in 2007-2008 and2010 in Strázovské Vrchy Protected Landscape Area (PLA) in Slovakia (included in the NATURA 2000 networking programme). Seven polymorphic microsatellite loci (UaMU26, UaMU64, G10b, G1D, G10L, UaMU50 and UaMU51) were amplified using a nested PCR in order to assess the following parameters: variability, allelic combinations, heterozygosity, number of alleles and inbreeding coefficient. Sufficient brown bear DNA for analysis was obtained from 57 out of 140 samples (41%), among which 45 different genotypes were identified. Loci had a mean of 2.71 ± 0.76 alleles. Average observed heterozygosity was 0.59. The inbreeding coefficient was negative for all but one of the analysed loci (2007-2008). In the year 2010 was negative three of seven loci. These results imply that gene flow with other parts of the population has been maintained in the reduced level and the isolation level of bears in the study area was not so low. Nevertheless, the genetic variability of bears in Strázovské Vrchy PLA was lower than that reported from other localities in the Carpathian Mountains. The results are discussed in the context of behavioural ecology and conservation genetics.

关键词： Carpathian Mountains European brown bear Ursus arctos L. Genetic Diversity Microsatellite Markers Non-Invasive Sampling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A knowledge base model for evaluation of bio-physical tendency of dryland

引用

Journal of Geographical Sciences 2004年第1期14卷 25-31页

作者： R jana M V KHIRE Centre of Studies in Resources Engineering Indian Institute of Technology PowaiMumbai-400 076 IndiaCentre of Studies in Resources Engineering Indian Institute of Technology PowaiMumbai-400 076 India

The present study aims the evaluation of bio-physical characteristics towards soil-water-vegetation stress and a rule is envisaged to assess the degree of temporal changes. The digital rule for assessment is initialized through the index of land Instability (ILI) where the variance indicates the temporal instability of the pixel i.e., smallest land unit. It is assumed that the biophysical characteristic of land is in command of land-dynamics where there is no change in Land Use/Land Cover (LU&LC). The intensity map on tendency of albedo (IALb) assesses the intensity of soil erosion and water stress whereas intensity map on tendency of NDVI (INDVI) appraises the stress on vegetation. The carry-out study covers a part of semiarid Western India. Primarily remote sensing technique, which carries the digital information of land temporally and spatially, is adopted in this paper. A part of the study area is represented using two sets of IRS 1A/1b LISS-I data of March with a decadal time domain (1989-1998) as a test area. It is assumed that the soil-water-vegetation stress is maximum during summer(March-April-May) in any tropical belt and decadal data will stretch the possibility of climate as well as man-made activity over the land.

关键词： assessment biophysical tendency degeneration land instability semiarid land India

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High temperature increases centromeremediated genome elimination frequency and enhances haploid induction in Arabidopsis

引用

Plant Communications 2023年第3期4卷 126-138页

作者： Ulkar Ahmadli Manikandan Kalidass Lucie Crhak Khaitova Joerg Fuchs Maria Cuacos Dmitri Demidov Sheng Zuo jana Pecinkova Martin Mascher Mathieu Ingouff Stefan Heckmann Andreas Houben Karel Riha Inna Lermontova Leibniz Institute of Plant Genetics and Crop Plant Research(IPK)Gatersleben Corrensstrasse 306466 SeelandGermany Central European Institute of Technology(CEITEC)and National Centre for biomolecular Research Faculty of ScienceMasaryk UniversityKamenice 562500 BrnoCzech Republic CIRAD DIADEIRDUniversity of Montpellier34393 MontpellierFrance

Double haploid production is the most effective way to create true-breeding lines in a single *** Arabidopsis,haploid induction via mutation of the centromere-specific histone H3(cenH3)has been shown when the mutant is outcrossed to the wild-type,and the wild-type genome remains in the haploid ***,factors that affect haploid induction are still poorly ***,we report that a mutant of the cenH3 assembly factor Kinetochore Null2(KNL2)can be used as a haploid inducer when pollinated by the *** discovered that short-term temperature stress of the knl2 mutant increased the efficiency of haploid induction *** also demonstrated that a point mutation in the CENPC-k motif of KNL2 is sufficient to generate haploid-inducing lines,suggesting that haploidinducing lines in crops can be identified in a naturally occurring or chemically induced mutant population,avoiding the generic modification(GM)approach at any ***,a cenh3-4 mutant functioned as a haploid inducer in response to short-term heat stress,even though it did not induce haploids under standard ***,we identified KNL2 as a new target gene for the generation of haploid-inducer lines and showed that exposure of centromeric protein mutants to high temperature strongly increases their haploid induction efficiency.

关键词： centromere kinetochore null 2 CENPC-k cenh3-4 temperature stress haploid induction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

MXene ink hosting zinc anode for high performance aqueous zinc metal batteries

引用

Journal of Energy Chemistry 2023年第1期76卷 187-194,I0005页

作者： Jae Min Park Milan jana Sang Ha baek Taehun Kang Peixun Xiong Jeong Hee Park Jun Soo Kim Ali Shayesteh Zeraati Mikhail Shekhirev Paul V.braun Yury Gogotsi Ho Seok Park School of Chemical Engineering Sungkyunkwan University2066SeoburoJangan-guSuwon 440-746Republic of Korea Department of Chemical and Petroleum Engineering University of Calgary2500 University Dr NWCalgary T2N 1N4Canada Department of Materials Science and Engineering Materials Research LaboratoryBeckman Institute for Advanced Science and TechnologyUniversity of Ilinois at Urbana-ChampaignUrbanaIL61801USA A.J.Drexel Nanomaterials Institute and Department of Materials Science and Engineering Drexel UniversityPhiladelphiaPA 19104USA SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan University2066SeoburoJangan-guSuwon 440-746Republic of Korea SKKU Advanced Institute of Nano Technology(SAINT) Sungkyunkwan University 2066SeoburoJangan-guSuwon 440-746Republic of Korea

Despite the safety,low cost,and high theoretical capacity(820 mA h g^(-1))of Zn metal anodes,the practical application of aqueous Zn metal batteries remains a critical challenge due to the Zn dendrite growth,corrosion,and hydrogen evolution ***,we demonstrate the MXene ink hosting Zn metal anodes(MX@Zn)for high-performance and patternable Zn metal full *** as-designed MX@Zn electrode is more facile and reversible than bare Zn and CC@Zn,as verified by better cyclic stability and lower overpotentials of symmetric cells with the plating capacity of 0.05 mA h cm^(-2)at 0.1 m A cm^(-2)and of 1 m A h cm^(-2)at 1 m A cm^(-2).The MX@Zn|MnO_(2)full cells deliver a high specific capacity of 281.9 m A h g^(-1),91.5%of the theoretical capacity,achieving 50%capacity retention from 60 mA g^(-1)to 300 mA g^(-1)and 79.7%of initial capacity after 200 ***,the patterned devices based on the MX@Zn electrode achieve high energy and power densities of 348.57 Wh kg^(-1)and 1556 W kg^(-1),respectively,along with a capacity retention of 64%and Coulombic efficiency of 99%over 500 *** high performance of MX@Zn is attributed to the high electrical conductivity and hydrophilicity of MXene and rapid ion diffusion through the 3D interconnected porous channels.

关键词： MXene ink Zinc anode Metal batteries Patterning Electrodeposition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Digital ischemic necrosis caused by pegylated interferon in a patient with hepatitis C

引用

World Journal of Gastrointestinal Pharmacology and Therapeutics 2011年第1期2卷 6-8页

作者： jana G Hashash Sean A Tackett David J McAdams Department of General Internal Medicine University of Pittsburgh Medical Center

Pegylated interferon plus ribavirin remains the firstline treatment for patients with hepatitis C virus(HCV) . Interferonαhas the most extensive clinical application and is used for the treatment of chronic hepatitis b virus and hepatitis D virus as well as acute and chronic HCV *** attachment of polyethylene glycol to interferon increases its half-life by reducing the rate of absorption after injection,reducing renal and cellular clearance and also decreasing *** this case report,we have described a patient with chronic hepatitis C who developed ischemic necrosis of her fingertips after completing her third course of pegylated interferon and *** patient underwent a very extensive workup in order to determine the underlying cause of her digital ischemia which was finally determined to be secondary to the use of pegylated interferon.

关键词： Pegylated interferon Interferon Hepatitis C Necrosis Ischemia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于世界卫生组织精神卫生立法检查清单的中国与印度尼西亚精神卫生法比较研究

基于世界卫生组织精神卫生立法检查清单的中国与印度尼西亚精神卫...

引用

作者： Gede bagus Subha jana Giri 吉林大学

学位级别：硕士

近年来精神障碍和社会心理问题的患病率显著增加。精神障碍患者是最脆弱的人群之一,他们的政治、经济、社会和文化权利经常被忽视,在利用卫生保健、保险、就业和住房方面也受到歧视。精神卫生立法可以提高精神障碍患者的生活水平,可以... 详细信息

近年来精神障碍和社会心理问题的患病率显著增加。精神障碍患者是最脆弱的人群之一,他们的政治、经济、社会和文化权利经常被忽视,在利用卫生保健、保险、就业和住房方面也受到歧视。精神卫生立法可以提高精神障碍患者的生活水平,可以为保护精神障碍患者的基本人权提供保障,还可以为精神障碍患者的社区融合,改善其获得卫生保健的机会,保护公民权利,以及住房、教育和就业等关键问题的解决提供法律框架。精神卫生法成为促进精神障碍患者获得精神保健服务,促进和保护其权利的有效工具。事实上,精神卫生系统的建立是一个循序渐进的过程,尽管一些国家已经建立了精神卫生法,但是其精神卫生体系仍然需要进一步完善。国家需要对精神卫生立法不断进行审查、修订和修正,不断提高其质量。世界卫生组织于2005年发布了一份关于精神卫生立法的检查清单,目的是为各国制定以人权为中心的精神卫生法提供指导。这份清单不是一套绝对的规则,它有助于各国评估其精神卫生立法是否已包括了关键组成部分,也有助于拉近各国精神卫生立法与《世界人权宣言》之间的联系。目的精神卫生立法的目的是保护、促进和改善公民的生活和精神健康。制定精神卫生法可以成为保护和促进人们获得利用精神卫生服务权利的有效工具。中国和印度尼西亚都制定了精神卫生法来保护精神障碍患者的权利。然而,精神卫生法本身的执行并不能确保尊重人权。因此,有必要对精神卫生立法进行分析,以确定精神卫生立法的内容是否能为精神卫生障碍患者提供保护。精神卫生系统的发展不是一蹴而就的,它需要不断的完善来提高精神卫生服务的质量。本研究的目的:1)根据世界卫生组织精神卫生立法检查清单,对中国和印度尼西亚的精神卫生法进行比较,分析其立法符合世界卫生组织检查清单的程度;2)为中国和印度尼西亚精神卫生系统的发展提供建议。方法本研究采用文献研究和专家访谈法。以世界卫生组织公布的精神卫生立法检查清单(2005年)为基本框架,在中国和印度尼西亚分别采访了一名具有法律或卫生法经验的专家,对各自国家的精神卫生法及相关的法律对照世界卫生组织检查清单进行打分,并解释理由。访谈的印度尼西亚专家是一名律师,支持并担任法律规划工作,目前在多所大学担任法律讲师;中国的专家是某大学卫生法专业教授,同时在中国卫生法专业学会任职。本研究采用的专家访谈法在先前Kelly等评估英格兰,威尔士和爱尔兰精神卫生立法,Richard评估印度精神卫生立法时均应用过。两名专家对各自国家的精神卫生法及相关法律对照世界卫生组织检查清单(2005年)进行评估,世界卫生组织2005年精神卫生法检查清单由175个条款组成,分为27个部分:A:序言和目的;b:定义;C:精神卫生服务的获得;D:患者获得精神健康服务的权利;E:家庭成员和其他护理人员的权利;F:法律能力及监护;G:自愿住院和治疗;H:无自主决定能力患者;I:非自愿住院(独立于住院)和非自愿治疗(住院和治疗结合);J:非自愿治疗(独立于非自愿住院);K:代理人对治疗的知情同意;L:社区中的非自愿治疗;M:紧急情况;N:精神障碍的确定;O:特殊治疗;P:隔离,限制;Q:临床与实验研究;R:监督和审查机制;S:警方职责;T:犯罪的精神障碍患者;U:歧视;V:住房;W:就业;X:社会保障;Y:人权问题;Z:对弱势社群的保护;AZ:罚则。这份清单可以帮助各国审查现有精神卫生立法的全面性和充分性。根据2014年Sotelo-Monroy的研究,我们按照以下方法对三种可能的答案进行赋值:(a)如果该材料完全符合法律规定,或在精神卫生法中没有规定,但在其他法律中有规定,则得分为2;(b)精神卫生法有规定,但不全面的为1分;(c)完全不包括在内的为0分。如果为(b),请解释为何没有充分涵盖,现有条文有何欠缺或问题。如果为(c),请解释为何现行法律不包括(如有需要,可将额外资料加入新页)。如果为(b)或(c),请说明如何/是否将其列入新法律。每个国家精神卫生立法条款与世界卫生组织检查清单的符合程度为每位专家依据世界卫生组织检查清单对各自国家精神卫生立法的评分除以世界卫生组织检查清单中该条目的最大值乘以100%,世界卫生组织检查清单包括177个项目,因此总分为354分。计算公式为:符合率:专家对每个国家精神卫生立法的评分/世界卫生组织检查清单中该条款的最大值×100%为了分析立法与世界卫生组织检查清单的符合程度,我们将结果分为4个级别符合性非常高(75-100%)、符合性一般(50-74%)、符合性较低(25-49%)和符合性非常低(低于24%)。结果1.中国精神卫生法与世界卫生组织检查清单符合率非常高的条款包括:A)序言和目的,(C)精神卫生服务的获得,(D)患者获得精神健康服务的权利,(G)自愿住院和治疗,(H)无自主决定能力患者,(N)精神障碍的确定,(S)警方职责,(U)歧视,W(就业

关键词：精神卫生法中国印度尼西亚世界卫生组织精神卫生法检查清单比较

来源：

同方学位论文库评论

在线全文

同方学位论文库

学校读者我要写书评

暂无评论

Evaluation of Effects of C60 Fullerene and Its Derivatives on Selected Microorganisms

引用

材料科学与工程（中英文b版） 2013年第7期3卷 409-417页

作者： Hana Kubatova Eva Zemanova Karel Klouda Karel bilek jana Kadukova State Office for Nuclear Safety Praha 110 00 Czech Republic National Institute for Nuclear Chemical and Biological Protection Milin 262 31 Czech Republic Technical University of Kosice Faculty of Metallurgy Kosice 042 00 Slovak Republic

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Indoor Radon Concentrations of School buildings in Varna District, bulgaria

引用

Journal of Environmental Science and Engineering(b) 2022年第2期11卷 43-48页

作者： Desislava Djunakova bistra Kunovska jana Djounova Kremena Ivanova Zdenka Stojanovska National Centre of Radiobiology and Radiation Protection Sofia 1606Bulgaria Faculty of Medical Sciences Goce Delcev UniversityStip 2000Republic of North Macedonia

Radon is a radioactive gas that is naturally produced by the breakdown of uranium in soil,rock and *** International Commission on Radiological Protection(ICRP)and World Health Organization(WHO)requirements include controlling indoor radon exposure and settings of a reference level for the annual average activity concentration of up to 300 bq/m3 for dwellings and public *** measurements in school buildings have long been carried out in many *** measurements in schools in bulgaria have started and are *** study concerns the measurements of radon concentration(CRn)in all state school buildings in one of the black Sea regions,Varna district,and the analysis of indoor *** survey of 1,185 premises of 107 schools was conducted from December 2019/January 2020 to March/May 2020 using a passive *** AM(Arithmetic Mean)of CRn in the premises of the studied schools on the territory of Varna district is 130 bq/m^(3),and the geometric mean is 97 bq/m^(3).The number of premises exceeding the national reference level of 300 bq/m^(3) is 72 located in 38 schools(about 36% of schools).A statistically significant difference(KW(Kruskal-Wallis),pbetween the radon data,grouped by ***,the radon data were classified into two groups based on municipality location:on the black Sea coast and *** located near the sea have a higher value of *** order to more accurately assess the exposure of pupils and teachers,the results are divided into four groups,depending on the type of use of the premises and the floor on which they are *** highest CRn value was found in the study rooms used for specialized education such as physics,chemistry,music etc.(AM=155 bq/m3),which can be explained by their smaller size and less frequent use.A statistically significant difference(KW,p<0.0001)was found,which means that the radon exposure in the examined rooms depends on the type of use.T

关键词： Radon schools measurement classrooms bulgaria

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：