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Epidemiology of insertional and midportion Achilles tendinopathy in runners:A prospective cohort study

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Journal of Sport and Health Science 2024年第2期13卷 256-263页

作者： Wenbo Chen Kyra l.A.Cloosterman Sita M.A.Bierma-Zeinstra Marienke van Middelkoop Robert-jan de Vos Department of Orthopaedic Surgery and Sports Medicine Erasmus MC University Medical CenterRotterdam 3015GDthe Netherlands Department of General Practice Erasmus MC University Medical CenterRotterdam 3015GDthe Netherlands Department of Sports Medicine Huashan HospitalFudan UniversityShanghai 200040China

Background:Achilles tendinopathy(AT)is a common problem among *** is only limited evidence for risk factors for AT,and most studies have not defined the AT *** study has compared the incidence and risk factors between insertional AT and midportion AT,though they are considered *** study aimed to assess incidence and risk factors of AT based on data from a large prospective *** secondary aim was to explore differences in risk factors between insertional and midportion ***:Participants were recruited from among registered runners at registration for running *** were completed at baseline,1 month before the event,1 week before the event,and 1 month after the *** concerning demographics,training load,registered events,and running-related injuries were collected at *** follow-up questionnaires collected information about new injuries.A pain map was used to diagnose midportion and insertional *** primary outcome was the incidence of *** logistic regression analysis was applied to identify risk factors for the ***:We included 3379 participants with a mean follow-up of 20.4 *** incidence of AT was 4.2%.The proportion of insertional AT was 27.7%and of midportion AT was 63.8%;the remaining proportion was a combined type of insertional and midportion *** had a significantly higher incidence(5%,95%confidence interval(95%CI):4.1%-6.0%)than women(2.8%,95%CI:2.0%-3.8%).AT in the past12 months was the most predominant risk factor for new-onset AT(odds ratio(OR)=6.47,95%CI:4.27-9.81).This was similar for both subcategories of AT(insertional:OR=5.45,95%CI:2.51-11.81;midportion:OR=6.96,95%CI:4.24-11.40).Participants registering for an event with a distance of 10/10.55 km were less likely to develop a new-onset AT(OR=0.59,95%CI:0.36-0.97)or midportion AT(OR=0.47,95%CI:0.23-0.93).Higher age had a significant negative association with insertional AT(OR=0.97,95%CI:0.9

关键词： Achilles tendon injury Incidence Risk factor Running-related injury

Improved Belief Propagation Decoder for lDPC-CRC-Polar Codes with Bit-Freezing

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China Communications 2024年第7期21卷 135-148页

作者： Qasim jan Yin Chao Pan Zhiwen Muhammad Furqan Zakir Ali You Xiaohu National Mobile Communications Research laboratory Southeast UniversityNanjing 210096China Purple Mountain laboratories Nanjing 211100China Department of Computer Science National University of Computer and Emerging Sciences Peshawar Campus 25100Pakistan Department of Software Engineering Capital University of Science and Technology(CUST)Islamabad 44000Pakistan Department of Computer Sciences Bahria University Lahore CampusPakistan

Though belief propagation bit-flip(BPBF)decoding improves the error correction performance of polar codes,it uses the exhaustive flips method to achieve the error correction performance of CA-SCl decoding,thus resulting in high decoding complexity and *** alleviate this issue,we incorporate the lDPC-CRC-Polar coding scheme with BPBF and propose an improved belief propagation decoder for lDPC-CRC-Polar codes with bit-freezing(lDPCCRC-Polar codes BPBFz).The proposed lDPCCRC-Polar codes BPBFz employs the lDPC code to ensure the reliability of the flipping set,i.e.,critical set(CS),and dynamically update *** modified CS is further utilized for the identification of error-prone *** proposed lDPC-CRC-Polar codes BPBFz obtains remarkable error correction performance and is comparable to that of the CA-SCl(l=16)decoder under medium-to-high signal-to-noise ratio(SNR)*** gains up to 1.2dB and 0.9dB at a fixed BlER=10-4compared with BP and BPBF(CS-1),*** addition,the proposed lDPC-CRC-Polar codes BPBFz has lower decoding latency compared with CA-SCl and BPBF,i.e.,it is 15 times faster than CA-SCl(l=16)at high SNR regions.

关键词： belief propagation bit-flipping concatenated codes lDPC-CRC-Polar codes polar codes

liquid crystal immunosensors for the selective detection of Escherichia coli with a fast analysis tool

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Photonics Research 2024年第7期12卷 1564-1573页

作者： SANDRO C.OlIVEIRA MARIA S.SOARES BÁRBARA V.GONÇAlVES ANDREIA C.M.RODRIGUES AMADEU M.V.M.SOARES RITA G.SOBRAl NUNO F.SANTOS jan NEDOMA PEDRO l.AlMEIDA CARlOS MARQUES CICECO-Aveiro Institute of Materials Physics DepartmentUniversity of Aveiro3810-193 AveiroPortugal i3N Physics DepartmentUniversity of Aveiro3810-193 AveiroPortugal Associate laboratory i4HB-Institute for Health and Bioeconomy School of Sciences and TechnologyNOVA University of Lisbon1099-085 LisbonPortugal CESAM-Centre for Environmental and Marine Studies and Department of Biology University of Aveiro3810-193 AveiroPortugal Department of Telecommunications VSB-Technical University of OstravaOstrava 70800Czech Republic i3N-CENIMAT School of Sciences and TechnologyNOVA University of Lisbon1099-085 LisbonPortugal UnIRE ISELPolytechnic Institute of Lisbon1549-020 LisbonPortugal Department of Physics VSB-Technical University of OstravaOstrava 70800Czech Republic

The consumption of contaminated food may cause serious illnesses,and traditional methods to detect Escherichia coli are still associated with long waiting times and high costs given the necessity to transport samples to specialized *** is a need to develop new technologies that allow cheap,fast,and direct monitoring at the site of ***,in this work,we developed optical immunosensors for the selective detection of ***,based on liquid crystal technology,whose molecules can align in different manners depending on the boundary conditions (such as substrates) as well as the environment that they *** glass substrate was functionalized with *** antibody using cysteamine as an intermediate,and a vertical alignment was imposed on the liquid crystal molecules by using DMOAP during *** presence of bacteria disrupts the alignment of the liquid crystal molecules,changing the intensity of light emerging between cross polarizers,measured using a polarized optical microscope and a *** was possible to detect *** in suspensions in the concentration range from 2.8 cells/ml to 2.8×10^(9) cells∕*** was also evaluated,and the sensors were used to analyze contaminated water samples.A prototype was developed to allow faster,in-situ,and easier analysis avoiding bulky instruments.

关键词： crystal alignment analysis

Enhanced thermal emission from metal-free,fully epitaxial structures with epsilon-near-zero InAs layers

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Journal of Semiconductors 2024年第2期45卷 34-39页

作者： Karolis Stašys Andrejus Geižutis jan Devenson State Research Institute Center for Physical Sciences and Technology Savanoriųave.231L-T02300 VilniusLithuania

We introduce a novel method to create mid-infrared(MIR)thermal emitters using fully epitaxial,metal-free *** the strategic use of epsilon-near-zero(ENZ)thin films in InAs layers,we achieve a narrow-band,wide-angle,and p-polarized thermal emission *** approach,employing molecular beam epitaxy,circumvents the complexities associated with current layered structures and yields temperature-resistant emission *** findings contribute a promising route towards simpler,more efficient MIR optoelectronic devices.

关键词： epsilon-near-zero thermal emitters indium arsenide lWIR(long wave infraRed) molecular beam epitaxy

Hepatic steatosis is associated with an increased risk of carotid atherosclerosis

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World Journal of Gastroenterology 2005年第12期11卷 1848-1853页

作者： Henry V(o|¨)lzke Daniel M.Robinson Volker Kleine Roland Deutscher Wolfgang Hoffmann jan l.demann Ulf Schminke Christof Kessler Ulrich John Institute of Epidemiology and Social Medicine Department of Internal Medicine B Institute for Community Medicine Institute of Clinical Chemistry and laboratory Medicine Department of Neurology

AIM: Although an association between hepatic steatosis and vascular risk factors has been described, direct relationships between fatty liver and atherosclerosis have not yet been investigated. The aim of the present study has been to investigate those relationships. METHODS: The Study of Health in Pomerania examined a random population sample aged between 20 and 79 years. A study population of 4 222 subjects without hepatitis B and C infections and without liver cirrhosis was available for the present analysis. Hepatic steatosis was defined sonographically and intima-media thickness (IMT) as well as plaque prevalence were estimated by carotid ultrasound. RESUlTS: The prevalence rate of hepatic steatosis was 29.9%. Among subjects aged ≥45 years, an association between hepatic steatosis and IMT of the carotid arteries was found in bivariate analysis, but not after adjustment for atherosclerotic risk factors. Individuals with fatty liver had more often carotid plaques than persons without fatty liver (plaque prevalence rate 76.8% vs 66.6%; Ply present in subjects with no to mild alcohol consumption. CONClUSION: There is an independent association between hepatic steatosis and carotid atherosclerotic plaques. Metabolic changes due to nonalcoholic fatty liver disease may explain this relationship.

关键词： Hepatic steatosis Fatty liver Atherosclerosis Study of Health in Pomerania

Mogroside IIE,an in vivo metabolite of sweet agent,alleviates acute lung injury via Pla2g2a-EGFR inhibition

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Food Science and Human Wellness 2024年第1期13卷 299-312页

作者： Weichao lü Guoqing Ren Kuniyoshi Shimizu Renshi li Chaofeng Zhang State Key laboratory of Natural Medicines School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Sino-jan Joint lab of Natural Health Products Research School of Traditional Chinese PharmacyChina Pharmaceutical UniversityNanjing 211198China Faculty of Agriculture Kyushu UniversityFukuoka 819-0395Japan

In the face of increasingly serious environmental pollution,the health of human lung tissues is also facing serious *** IIE(M2E)is the main metabolite of sweetening agents mogrosides from the anti-tussive Chinese herbal Siraitia *** study elucidated the anti-inflammatory action and molecular mechanism of M2E against acute lung injury(AlI).A lipopolysaccharide(lPS)-induced AlI model was established in mice and MH-S cells were employed to explore the protective mechanism of M2E through the western blotting,co-immunoprecipitation,and quantitative real time-PCR *** results indicated that M2E alleviated lPS-induced lung injury through restraining the activation of secreted phospholipase A2 type IIA(Pla2g2a)-epidermal growth factor receptor(EGFR).The interaction of Pla2g2a and EGFR was identified by *** addition,M2E protected AlI induced with lPS against inflammatory and damage which were significantly dependent upon the downregulation of AKT and m TOR via the inhibition of ***2g2a may represent a potential target for M2E in the improvement of lPS-induced lung injury,which may represent a promising strategy to treat AlI.

关键词： Mogroside IIE Acute lung injury Secreted phospholipase A2 type IIA(Pla2g2a) Epidermal growth factor receptor(EGFR)

Haplotype-based phylogenetic analysis and population genomics uncover the origin and domestication of sweetpotato

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Molecular Plant 2024年第2期17卷 277-296页

作者： Mengxiao Yan Ming li Yunze Wang Xinyi Wang M-Hossein Moeinzadeh Dora G.Quispe-Huamanquispe Weijuan Fan Yijie Fang Yuqin Wang Haozhen Nie Zhangying Wang Aiko Tanaka Bettina Heider jan F.Kreuze Godelieve Gheysen Hongxia Wang Martin Vingron Ralph Bock Jun Yang Shanghai Key laboratory of Plant Functional Genomics and Resources Shanghai Chenshan Botanical GardenShanghai 201602China College of life Sciences Chongqing Normal UniversityChongqing 401331China Biotechnology and Nuclear Technology Research Institute Sichuan Academy of Agricultural SciencesChengdu 610061China College of life Sciences Shanghai Normal UniversityShanghai 200234China Department of Computational Molecular Biology Max Planck Institute for Molecular GeneticsIhnestraBe 63-7314195 BerlinGermany Department of Biotechnology Ghent University9000 GhentBelgium Guangdong Provincial Key laboratory of Crops Genetics and Improvement Crop Research InstituteGuangdong Academy of Agricultural SciencesGuangzhou 510640China Graduate School of Bioagricultural Sciences Nagoya UniversityChikusaNagoya 464-8601Japan international Potato Center(CIP) LimaPeru CAS Center for Excellence of Molecular Plant Sciences Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200233China Max-Planck-Institut fur Molekulare Pflanzenphysiologie Am Muhlenberg 114476 Potsdam-GolmGermany

The hexaploid sweetpotato(lpomoea batatas)is one of the most important root crops ***,its genetic origin remains controversial,and its domestication history remains *** this study,we used a range of genetic evidence and a newly developed haplotype-based phylogenetic analysis to identify two probable progenitors of *** diploid progenitor was likely closely related to lpomoea ae-quatoriensis and contributed the B,subgenome,IbT-DNA2,and the lineage 1 type of chloroplast genome to *** tetraploid progenitor of sweetpotato was most likely *** 4x,which donated the B2 subgenome,IbT-DNA1,and the lineage 2 type of chloroplast *** most likely originated from reciprocal crosses between the diploid and tetraploid progenitors,followed by a subsequent whole-genome *** addition,we detected biased gene exchanges between the subgenomes;the rate of B,to B2 subgenome conversions was nearly three times higher than that of B2 to B subgenome *** analyses revealed that genes involved in storage root formation,maintenance of genome stabil-ity,biotic resistance,sugar transport,and potassium uptake were selected during the speciation and domestication of *** study sheds light on the evolution of sweetpotato and paves the way forimprovementofthiscrop.

关键词： sweetpotato origin gene conversion domestication IbT-DNA HPA

Measuring NO Production by Plant Tissues and Suspension Cultured Cells

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Molecular Plant 2008年第2期1卷 270-284页

作者： jan Vitecek Vilem Reinohlt Russell l. Jones Department of Plant Biology Faculty of Agronomy Mendel University of Agriculture and Forestry Zemedelska 1 Brno 613 00 Czech Republic Department of Plant and Microbial-Biolocjy University of California Berkeley CA 94720-3102 USA

We describe an inexpensive and reliable detector for measuring NO emitted in the gas phase from plants. The method relies on the use of a strong oxidizer to convert NO to NO2 and subsequent capture of NO2 by a Griess reagent trap. The set-up approaches the sensitivity for NO comparable to that of instruments based on chemiluminescence and photoacoustic detectors. We demonstrate the utility of our set-up by measuring NO produced by a variety of well established plant sources. NO produced by nitrate reductase （NR） in tobacco leaves and barley aleurone was readily detected, as was the production of NO from nitrite by the incubation medium of barley aleurone. Arabidopsis mutants that overproduce NO or lack NO-synthase （AtNOS1） also displayed the expected NO synthesis phenotype when assayed by our set-up. We could also measure NO production from elicitor-treated suspension cultured cells using this set-up. Further, we have focused on the detection of NO by a widely used fluorescent probe 4-amino-5-methylamino-2＇,7＇-difluorofluorescein （DAF-FM）. Our work points to the pitfalls that must be avoided when using DAF-FM to detect the production of NO by plant tissues. In addition to the dramatic effects that pH can have on fluorescence from DAF-FM, the widely used NO scavengers 2-phenyl- 4,4,5, 5-tetramethylimidazoline- 1-oxyl-3-oxide （PTIO） oxide （cPTIO） can produce anomalous and unexpected to bind to dead cells and remain NO-sensitive. and 2-（4-carboxyphenyl）-4,4,5,5-tetramethylimidazoline- 1-oxyl-3- results. Perhaps the most serious drawback of DAF-FM is its ability to bind to dead cells and remain NO-sensitive.

关键词： Measuring NO Production Plant Tissues Suspension Cultured Cells

Plastins:versatile modulators of actin organization in (patho)physiological cellular processes

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Acta Pharmacologica Sinica 2005年第7期26卷 769-779页

作者： Veerle DElANOTE Jo■l VANDEKERCKHOVE jan GETTEMANS Department of Medical Protein Research Flanders Interuniversity Institute for Biotechnology(VIB) Ghent University Faculty of Medicine and Health Sciences Albert Baertsoenkaai 3 B-9000 Ghent Belgium Department of Medical Protein Research Flanders Interuniversity Institute for Biotechnology(VIB) Ghent University Faculty of Medicine and Health Sciences Albert Baertsoenkaai 3 B-9000 Ghent Belgium Department of Medical Protein Research Flanders Interuniversity Institute for Biotechnology(VIB) Ghent University Faculty of Medicine and Health Sciences Albert Baertsoenkaai 3 B-9000 Ghent Belgium

Many actin-binding proteins are expressed in eukaryotic *** polypep-tides assist in stabilizing and rearranging the organization of the actin cytoskel-eton in response to external stimuli,or during cell migration and *** review a particular set of actin-binding proteins called ***(alsocalled fimbrins)belong to a subclass of actin-binding proteins known as actinbundling *** isoforms have been characterized in mammals:T-plastinis expressed in cells from solid tissue,whereas l-plastin occurs predominantly inhematopoietic *** third isoform,I-plastin,is specifically expressed in thesmall intestine,colon and *** proteins share the unique property ofcross-linking actin filaments into fight *** plastins are primarilyinvolved in regulation of the actin cytoskeleton,they possess some *** instance,they are implicated in invasion by pathogenic bacteriasuch as Shigellaflexneri and Salmonella ***,l-plastin plays animportant role in leukocyte function.T-plastin,on the other hand,is possiblyinvolved in DNA ***,both T-and l-plastin are implicated in severaldiseases,and l-plastin is considered to be a valuable marker for cancer.

关键词： actin actin-binding protein plastin cytoskeleton