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Resveratrol,a Natural Antioxidant,Attenuates the Vasculopathy in Diabetic Rats

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MODELING THE FATE AND TRANSPORT OF HYDROPHOBIC ORGANIC COMPOUNDS IN AN UNSTEADY RIVER-ESTUARINE SYSTEM

第14届国际自由基学术大会

作者： jan-Kan chen Department of physiology college of Medicine Chang Gung University

＜正＞Vasculaopathy is one of the leading cause of the mortality and morbidity in diabetes mellitus （DM） patients. Amelioration of the diabetic angiopathy may effectively delay the progression of DM, and decrease th...

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International Journal of Sediment Research 2002年第3期17卷 197-210页

作者： Su-Chin chen,jan-Tai KUO Professor Department of Soil and Water Conservation National Chung-Hsing University Taichung 402 Taiwan China Professor Department of Civil Engineering National Taiwan University Taipei 106 Taiwan China

This research develops a generalized, one-dimensional, finite difference model for simulating the distribution of toxic substances in a river-estuarine system. The three sub-models for unsteady flow, sediment transport, and the reaction of toxic substances are also presented using an uncoupled numerical method. The paper also includes experimental work for sorption/desorption, field measurements of organic carbon content in the heavily polluted Keelung River, and a laboratory study of cohesive sediment transport for the model calibration and verification. In addition, this study simulates the polycyclic aromatic hydrocarbons (PAHs) in the Keelung River in northern Taiwan as a case study. Encouraging results are obtained, and suggest that the modeling approach could be extended to simulate the fate and transport of sorbed pollutants in tidal river.

关键词： Toxic substance model Tidal flow Sediment transport Sorption and desorption kinetics Polycyclic Aromatic Hydrocarbons (PAHs) Keelung River

Intelligent Automation Module-Based Gear Edge Grinding System

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Journal of Mechanics Engineering and Automation 2020年第1期10卷 27-36页

作者： cheng-Kai Huang Yeou-Bin Guu Chwen-Yi Yang Yi-Ying Lin jan-Hao chen Industrial Technology Research Institute Hsinchu 31040TaiwanR.O.C.

As industry progresses toward intelligent production and development,on-site workers that perform repetitive tasks will be replaced by intelligent ***,automation applications still have the following problems:(1)on-site personnel are required to line up the workpieces before a robot arm can pick it up;(2)the trajectory generated by offline programming software must be adjusted by on-site personnel in accordance with the processing results;and(3)because of workpiece positioning errors and tool wear,achieving acceptable processing results is *** study developed intelligent application modules that solve the aforementioned automation application *** modules predict processing quality,generate trajectory,enable robot arms to load and unload randomly positioned workpieces,and automatically calibrate the *** automatic gear edge grinding system was developed by integrating each module;the system increases the processing efficiency and solves the current problem of manual grinding being required after gear processing.

关键词： Intelligent automation module grinding calibration

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基于增强现实技术的物联网数据呈现与交互

包装工程 2017年第20期38卷 42-47页

作者：孙效华张绳宸 jan Dornig 同济大学上海200082

目的分析运用增强现实技术支持物联网数据呈现与交互的应用方式,并归纳其技术实现所需要的支持,为进一步的研究与应用提供思路和方法。方法根据增强现实技术应用于物联网数据呈现与交互的适用特性,对其应用可能进行分析描述。结论增强... 详细信息

目的分析运用增强现实技术支持物联网数据呈现与交互的应用方式,并归纳其技术实现所需要的支持,为进一步的研究与应用提供思路和方法。方法根据增强现实技术应用于物联网数据呈现与交互的适用特性,对其应用可能进行分析描述。结论增强现实技术在物联网数据呈现、数据关联、数据交互、数据模拟、远程增强与协同操作等方面均有广阔的应用空间,能够提高数据呈现与交互过程中的直观程度、降低认知负担、支持更多样的呈现与交互形式,帮助建立更加智能与易用的物联网系统。

关键词：增强现实物联网数据呈现与交互

Reduced bile duct contractile function in rats with chronic hyperglycemia

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Health 2010年第9期2卷 1072-1077页

作者： Chi-Ming Liu Hui-chen Su Yen-Ting Wang Tao-Hsin Tung Pesus Chou Yiing-Jeng Chou Jorn-Hon Liu jan-Kan chen 不详

The incidence of gallstone is higher in patients with diabetes mellitus than in general popula- tion. It is generally attributed to hypomotility and lowered emptying function of the gallblad- der. In this study, we investigate if chronic hy- perglycemia is correlated with reduced contrac- tile function of the bile ducts in rat. Hypergly- cemic rats were induced by streptozotocin-nic-otinamide treatment. Hyperglycemic rats were sacrificed eight months after induction and bile ducts were removed for the subsequent studies. The bile duct contractility of the normal rats is consistently higher than that of the hypergly- cemic rats. The contractities were measured to be 5.5 ± 0.2 mg vs. 4.2 ± 0.1 mg without CCK stimulation, and 5.5 ± 0.3 mg vs. 7.9 ± 0.4 mg with CCK stimulation, respectively for hypergly-cemic and normal rats. There was no significant difference in plasma CCK concentration in hy- perglycemic rats and normal rats. The expres- sion of CCK-A receptor protein in the bile duct tissue was decreased in hyperglycemic rats compared with that of the normal rats, and it may, at least in part, responsible for a reduced contractility. A reduced bile duct motility may cause bile retention, and may be one of the factors predispose to gallstone formation in type 2 diabetes patients, which is characterized with chronic hyperglycemia.

关键词： Hyperglycemia Bile Duct Contractile

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大学英语基础阶段语法教学的思考

黑龙江教育学院学报 2007年第1期26卷 154-156页

作者：陈钧黔南民族师范学院外语系贵州都匀558000

大学英语基础阶段不能忽视语法教学。语法教学应注重传统语法与交际语法相结合,注重英汉语法的比较,重视口语语法,从而促进学生英语学习的进步,提高教学质量。

关键词：大学英语基础阶段语法教学

Resveratrol Protects Myocardium Against Ischemia-Reperfusion Injuries

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Resveratrol Protects Myocardium Against Ischemia-Reperfusion...

IN VITRO MODULATION OF ANTI-ANGIOGENIC ACTIVITY OF HUMAN LIMBO-CORNEAL EPITHELIAL CELLS

第六届全国自由基生物学与自由基医学学术会议和海峡两岸自由基生物学与自由基医学学术会议

作者： jan-Kan chen and Li-Man Hung Departments of Physiology and Life Sciences, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan

We previously showed that resveratrol (3,4’,5-trihydroxystilbene) stimulates NO production and is cardioprotective in rat heart subjected to ischemia-reperfusion (I/R rat heat). We now show that in I/R rat heart, inducible nitric oxide synthase (iNOS) expression is markedly induced, while expression of endothelial nitric oxide synthase (eNOS) and neuronal nitric oxide synthase (nNOS) is unchanged, In animals preconditioned with resveratrol (0.5 to 1 mg/kg body wt), I/R-induced iNOS induction is abrogated;however,expression of eNOS and nNOS is greatly upregulated. The protective effects of resveratrol on I/R rat heart include reduced rhythm disturbances, reduced cardiac infarct size, and decreased plasma levels of lactate dehydrogenase (LDH) and creatine kinase (CK). Among these, the reductions in LDH/CK levels and infarct size are NO-dependent as the coadministration of NW-nitro-L-arginine methyl ester (L-NAME, 1 mg/kg body wt) with resveratrol abolishes the resveratrol effect. In contrast, the reductions in the severity of ventricular arrhythmia and mortality rate are not affected by L-NAME coadministration, suggesting that a NO-independent mechanism is involved.

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IN VITRO MODULATION OF ANTI-ANGIOGENIC ACTIVITY OF HUMAN LIM...

以不同分类法探讨SPOT与IKONOS两种卫星影像之分类准确度

The 4th Asian-Pacific Organization for Cell Biology Congress Cell Biology in the Post-Genomic Era

作者： David H.-K.Ma Long-Quing Yeh Ray J.-F.Tsai jan-Kan chen Department of Ophthalmology Chang-Gung Memorial HospitalTaoyuan 333 Department of Physiology Chang-Gung UniversityTaoyuan 333

The corneal epithelial cells exhibit an unique anti-angiogenic activity which helps to maintain the avascularity of the cornea. However, little is known about the way to maximize this anti-angiogenic activity in a physiological way for transplantation purpose. We found that the in vitro anti-angiogenic activities of

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遥感学报 2006年第4期10卷 573-577页

作者：吴守从陈建璋陈朝圳实践大学观光管理学系屏东科技大学热带农业暨国际合作研究所屏东科技大学森林系

遥感探测可应用于大尺度环境之研究、规划及经营管理,故为探讨自然资源动态变迁之良好工具,惟现行影像来源与分类方法众多,研究者如何视其需要选择最佳组合,实有探讨之必要。本研究以SPOT及IKONOS两种不同空间解析力之卫星影像为材料,... 详细信息

遥感探测可应用于大尺度环境之研究、规划及经营管理,故为探讨自然资源动态变迁之良好工具,惟现行影像来源与分类方法众多,研究者如何视其需要选择最佳组合,实有探讨之必要。本研究以SPOT及IKONOS两种不同空间解析力之卫星影像为材料,配合不同分类方法探讨台湾地区垦丁公园不同植群社会之空间分布信息,其结果均证实可行。而由研究过程发现,不同影像使用不同分类方法,其分类准确度有所差异,其中IKONOS影像因具有较高之空间解析力,有时反而容易造成影像分类的误授、漏授;而绿色植生部分尚无法由卫星影像之波谱值完全区隔,因此分类之精度仍有待精进。就影像分类而言,良好的训练样区配合正确的分类方法,可迅速获得一定准确度以上之分类结果,惟有时限于分类别的影像波谱值过于接近及各种地形效应、辐射效应之影响,会造成影像分类结果有误授、漏授及破碎化之情形产生,若能有效克服此一问题,则影像分类之成果将可提高其实用性。

关键词：遥感探测分类准确度波谱信息