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对于“Stuart Crampin对Jordan等‘可操作性地震预报:发展现状和使用手册[2011]’评论”的回复

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国际地震动态 2013年第6期34卷 15-18页

作者： Thomas h Jordan Yun-Tai Chen Paolo Gasparini Raul Madariaga Ian Main warner Marzocchi Gerassimos Papadopoulos Gennady Sobolev Koshun Yamaoka Jochen Zschau 王生文 Southern California Earthquake Center Los AngelesUSA University of Southern California Department of Earth SciencesLos AngelesUSA Institute of Geophysics China Earthquake AdministrationBeijingChina AMRA(Analisi e Monitoraggio del Rischio Ambientale)Scarl NapoliItaly Universitàdi Napoli"Federico Ⅱ" Dipartimento di Scienze FisicheNapoliItaly cole Normale Supérieure Département des GéosciencesParisFrance University of Edinburgh School of GeoSciencesEdinburghUnited Kingdom Istituto Nazionale di Geofisica e Vulcanologia Sezione Roma 1RomeItaly Institute of Geodynamics National Observatory of AthensAthensGreece Institute of Physics of the Earth Russian Academy of SciencesMoscowRussia Research Center for Seismology Volcanology and Disaster MitigationGraduate School of Environmental StudiesNagoya UniversityJapan helmholtz-Zentrum Deutsches GeoForschungsZentrum GFZDepartment Physik der ErdePotsdamGermany 中国地震局地球物理研究所

在对国际地震预报委员会（ICEF）报告[1]的评论中,Crampin[2]声称剪切波分裂变化可以在短时间尺度上预测地震,并且可靠性高,技术性强。他对ICEF的一个重要发现提出挑战到目前为止,没有任何方法具有如此高的预测能力。特别是,Crampin宣称,

关键词：地震预报 Jordan 使用手册可操作性评论回复预测能力时间尺度

膳食纤维的摄入和结肠直肠癌的风险性:一项前瞻性队列研究的汇总分析

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世界核心医学期刊文摘（胃肠病学分册） 2006年第4期2卷 1-2页

作者： Park Y hunter D.J Spiegelman D. S.A. Smith.warner 王铮 Department of Nutrition Harvard School of Public Health 665 Huntington Ave Boston MA 02115 United StatesDr.

Context: Inconsistent findings from observational studies have continued the controversy over the effects of dietary fiber on colorectal cancer. Objective: To evaluate the association between dietary fiber intake and risk of colorectal cancer. Design, Setting, and Participants: From 13 prospective cohort studies included in the Pooling Project of Prospective Studies of Diet and Cancer, 725 628 men and women were followed up for 6 to 20 years across studies. Study-and sex-specific relative risks (RRs) were estimated with the Cox proportional hazards model and were subsequently pooled using a random-effects model. Main Outcome Measure: Incident colorectal cancer. Results: During 6 to 20 years of follow-up across studies, 8081 colorectal cancer cases were identified. For comparison of the highest vs lowest study-and sex-specific quintile of dietary fiber intake, a significant inverse association was found in the age-adjusted model (pooled R R = 0.84; 95%confidence interval [CI], 0.77-0.92). however, the association wa s attenuated and no longer statistically significant after adjusting for other r isk factors (pooled multivariate RR = 0.94; 95%CI, 0.86-1.03). In categorical analyses compared with dietary fiber intake of 10 to he pooled multiv ariate RR was 1.18 (95%CI, 1.05-1.31) for less than 10 g/d (11%of the overall study population); and RR, 1.00 (95%CI, 0.85-1.17) for 30 or more g/d. Fiber intake from cereals, fruits, and vegetables was not associated with risk of colo rectal cancer. The pooled multivariate RRs comparing the highest vs lowest study -and sex-specific quintile of dietary fiber intake were 1.00 (95%CI, 0.90-1. 11) for colon cancer and 0.85 (95%CI, 0.72-1.01) for rectal cancer (P for comm on effects by tumor site = .07). Conclusions: In this large pooled analysis, die tary fiber intake was inversely associated with risk of colorectal cancer in age -adjusted analyses. however, after accounting for other dietary risk factors, h igh dietary fi

关键词：结肠直肠癌前瞻性队列研究膳食纤维结肠癌特异性随访研究随机效应模型多变量分位数风险度

Enhanced recovery after surgery pathway: The use of fascia iliaca blocks causes delayed ambulation after total hip arthroplasty

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World Journal of Anesthesiology 2019年第2期8卷 13-18页

作者： jamie-Lee Metesky Junping Chen Meg Rosenblatt Anesthesia Department Mount Sinai St.Luke’s and West Hospitals

BACKGROUND Fascia iliaca compartment blocks(FIBs) have been used to provide postoperative analgesia after total hip arthroplasty(ThA). however, evidence of their efficacy remains limited. While pain control appears to be satisfactory, quadriceps weakness may be an untoward consequence of the block. Prior studies have shown femoral nerve blocks and fascia iliaca blocks as being superior for pain control and ambulation following ThA when compared to standard therapy of parenteral pain control. however, most studies allowed patients to ambulate on post-operative day(POD) 2-3, whereas new guidelines suggest ambulation on POD 0 is *** To determine the effect of FIB after ThA in patients participating in an enhanced recovery after surgery(ERAS) *** We conducted a retrospective analysis of patients undergoing ThA with or without FICBs and their ability to ambulate on POD 0 in accordance with ERAS protocol. Perioperative data was collected on 39 patients who underwent *** data, anesthesia data, and ambulatory outcomes were *** Twenty patients had FIBs placed at the conclusion of the procedure, while 19 did not receive a block. Of the 20 patients with FIB, only 1 patient was able to ambulate. Of the 19 patients without FIB blocks, 17 were able to ambulate. All patients worked with physical therapy 2 h after arriving in the post-anesthesia care unit on POD *** Our data suggests an association between FIB and delayed ambulation in the immediate post-operative period.

关键词： Fascia iliaca Total hip arthroplasty Enhanced recovery after surgery protocol Deep vein thrombus Post-operative

Dissociation Constant of N-(2-Acetamido)-Iminodiacetic Acid Monosodium (ADA) from (278.15 to 328.15) K

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Open Journal of Physical Chemistry 2014年第2期4卷 73-79页

作者： Rabindra N. Roy Lakshmi N. Roy John J. Dinga Mathew R. Medcalf Katherine E. hundley Eric B. hines Clark B. Summers Lucas S. Tebbe jamie Veliz Drury University Springfield USA

The acidic dissociation constant of N-(2-acetamido)-iminodiacetic acid monosodium (ADA) has been determined at 12 temperatures from 278.15 to 328.15 K by electromotive-force (emf) measurements of hydrogen-silver chloride cells without liquid junction. At 298.15 K, the value of the dissociation constant (pK2) is 6.8416 ± 0.0004. In response to the need for new physiological ph standards, buffer solutions of NaADA and its disodium salt, Na2ADA would be useful for ph control in the biological region of ph 6.5 to 7.5. The pK2 values over the experimental temperature range are given as a function of the thermodynamic temperature (T) by the equation pK2 = 2943.784/T - 47.05762 + 7.72703 ln T. At 298.15 K, standard thermodynamic quantities for the dissociation process have been derived from the temperature coefficients;Δh° = 12,252 J·mol-1, ΔS° = -89.9 J·K-1·mol-1 and = -148 J·K-1·mol-1. The results are interpreted and compared with those of structurally related derivatives of GLYCINE.

关键词： Dissociation Constant ADA Emf Buffer Thermodynamic Quantity

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多次失血对大鼠体重增长的影响

实验动物与比较医学 1982年第3期 116-116页

作者： Cardy.R.h. warner.J.W. 编审组编审组

在一些亚急性毒性实验中需要连续检查动物的血液.但是,取血量和次数受制于动物维持体内自动平衡的能力,一般认为,给成年大鼠每二周取血一毫升,不会影响此种平衡功能,不改变血液系和血清化学的正常值.本文报告在引癌试验之早期反复取血... 详细信息

在一些亚急性毒性实验中需要连续检查动物的血液.但是,取血量和次数受制于动物维持体内自动平衡的能力,一般认为,给成年大鼠每二周取血一毫升,不会影响此种平衡功能,不改变血液系和血清化学的正常值.本文报告在引癌试验之早期反复取血对大鼠体重增长的影响.取F344/Fcrc系大鼠,分为三组,每组52只.6周令.生活在正压空气中.室温为23.3±1.1℃,相对湿度为50±5%.每四分钟全通气一次.人工光照每昼夜12小时.饮水酸化达ph.2.5,饮食充足供应.三组中的两组经胃管灌入1.3-双气丙烯的玉米油液(两组分别为

关键词：大鼠体重增长

Thermodynamics of the Second Stage Dissociation Step (pK<sub>2</sub>) of Buffer Monosodium 1,4-Piperazinediethanesulfonate from (278.15 to 328.15) K

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Journal of Biophysical Chemistry 2014年第3期5卷 91-98页

作者： Rabindra N. Roy Lakshmi N. Roy John J. Dinga Matthew R. Medcalf Katherine E. hundley Eric B. hines Ryan R. Parmar jamie A. Veliz Clark B. Summers Lucas S. Tebbe hoffman Department of Chemistry Drury University Springfield USA

Values of the second thermodynamic dissociation constant pK2 of the protonated form of monosodium 1,4-piperazinediethanesulfonate (PIPES) have been determined at twelve different temperatures in the temperature range from (278.15 to 328.15) K including the body temperature 310.15 K by measurement of the electromotive-force for cells without liquid junction of the type: Pt (s), h2 (g), 101.325 kPa|Na-PIPES (m1) + Na 2-PIPES (m2) + NaCl (m3)|AgCl (s), Ag (s), where m1, m2 and m3 indicate the molalities of the corresponding species at 1 atm = 101.325 kPa in SI units. The pK2 values for the dissociation of Na-PIPES are represented by the equation: pK2 = -1303.76/T + 48.369 - 6.46889 lnT with an uncertainty of ± 0.001. The values of pK2 for Na-PIPES were found to be 7.1399 ± 0.0004 at 298.15 K and 7.0512 ± 0.0004 at 310.15 K, respectively, and indicate that this buffer would be useful as ph standard in the range of physiological application. Standard thermodynamic quantities for the acidic dissociation process of Na-PIPES have been derived from the temperature coefficients of the pK2. These values are compared with those of structurally related N-substituted PIPERAZINE and TAURINE at 298.15 K.

关键词： Dissociation Constant Zwitterion Ionic Strength pK2 Buffer Compound e.m.f Thermodynamic Quantities

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反义词

疯狂英语（初中天地） 2003年第29期 31-31页

作者： jamie

刚试你的反应能力:你能在十分钟内,从表里把下列各单词的反义词找出来,并填写在线土吗?1 .white2 .awake3 .heavy4 .h盯d5 .expensive 6 .stand 7 .short 8,fast 9,fat ***厅OW。P万从’Olu万甲’6怂015’8习uol’乙血叫。·9 IJo,,十〕... 详细信息

刚试你的反应能力:你能在十分钟内,从表里把下列各单词的反义词找出来,并填写在线土吗?1 .white2 .awake3 .heavy4 .h盯d5 .expensive 6 .stand 7 .short 8,fast 9,fat ***厅OW。P万从’Olu万甲’6怂015’8习uol’乙血叫。·9 IJo,,十〕q宕苍I’乞d。。15仑’乙 1琶S‘9X,lq’I:举场反义词@jamie

关键词：反义词

遗传性痉挛性截瘫的一种复杂表现形式:西尔弗综合征的临床、遗传学和候选基因研究

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世界核心医学期刊文摘（神经病学分册） 2005年第2期1卷 25-25页

作者： warner T.T. Patel h. Proukakis C. A.h. Crosby 杜芳 Dept. of Medical Genetics St. George’s Hospital Medical Sc hool Cranmer Terrace Tooting London SW17 0RE United Kingdom Dr.

Silver syndrome (SS) is a complicated form of hereditary spastic paraplegia as sociated with distal wasting of the small muscles of the hands. We have previous ly described a large kindred with SS and mapped a genetic locus (SPG17) to chrom osome 11q12 q14. In the current study we analyse the clinical phenotype and per form linkage analysis in three new SS families. In addition we analyse candidate genes mapping to the SS locus (SPG17). Clinical assessments were performed on 2 5 (15 affected) individuals from each family in which SS segregates with variabl e clinical expression. Neurophysiological studies, performed in the index case o f two families, suggested anterior horn cell or nerve root involvement. Linkage analysis using microsatellite markers mapping to the SPG17 locus was performed a nd only one of the three families had a microsatellite segregation pattern compa tible with linkage. Candidate genes mapping to the SS critical region were analy sed in this and one other SPG17 linked family. Mutation analysis of genes encodi ng calpain 1 (CAPN1), copper chaperone for superoxide dismutase (CCS), ADP ribos ylation factor like 2 (ARL2), LOC120664, a putative homologue of atlastin (ATLS TL 1) and sorting nexin 15 (SNX15) failed to identify any disease specific mut ations. SS therefore exhibits both clinical and genetic heterogeneity and the SP G17 locus may account for a significant proportion of SS mutations in the UK.

关键词：候选基因微卫星标记基因座分离方式前角细胞先证者遗传多态性核糖基化因子连锁分析临床表型

氙气在小鼠大脑中动脉短暂性梗塞模型上的神经元保护作用

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国外医学（麻醉学与复苏分册） 2004年第1期25卷 60-63页

作者： h.Mayumi homi Noriko Yokoo DaqingMa David S.warner Nicholas P.Franks MervynMaze M.B.Ch.B. F.R.C.P. F.R.C.A. hilaryP.Grocott F.R.C.P.C. 朱珊珊曾因明 DepartmentofAnesthesiology（MultidisciplinaryNeuroprotectionLaboratories） DukeUniversityMedicalCenter. DepartmentsofAnestheticsandBiologicalSciences ImperialCollegeofScienceTechnologyandMedicineLondonUaitedKingdom. 徐州医学院江苏省麻醉学重点实验室221002

麻醉气体，其特性包括相对较高的心血管安全性(同等或优于传统麻醉药)，与其他大多数气体相比较好的药物动力学或药效学特点。越来越多的临床和实验研究表明，氙气作为一种气体麻醉药，具有镇痛、诱导苏醒迅速和对心血管影响小的特点。... 详细信息

麻醉气体，其特性包括相对较高的心血管安全性(同等或优于传统麻醉药)，与其他大多数气体相比较好的药物动力学或药效学特点。越来越多的临床和实验研究表明，氙气作为一种气体麻醉药，具有镇痛、诱导苏醒迅速和对心血管影响小的特点。另外，由于其对环境影响小，因此适用于吸入麻醉。但是，由于其价格昂贵，在临床应用中也因此受到了限制。

关键词：氙气小鼠大脑动脉短暂性梗塞动物模型神经元保护麻醉