检索结果-南通市图书馆

心肺血管病杂志 1985年第1期 9-11页

作者： james s.t.yao 刘复兴

在美国腹主动脉瘤多,且发生于肾动脉以下的占90%,25%合并髂、股、(?)等动脉狭窄,并常见可合并肢体远端动脉瘤,特别是(?)窝动脉瘤,多数为棱形,少数为囊状,2%以上为肾动脉以上主动脉瘤,或称胸腹主动脉瘤。

关键词：腹主动脉瘤肾动脉人工血管人工器官补片

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

血管外科的进展

心肺血管病杂志 1985年第1期 4-5页

作者： james s.t.yao 刘复兴

一、血管外科发展史:早在1522年AMDROIsE PARE就作了动脉瘤结扎术。1628年WILLIAM HARVEY发现血液循环推动了血管外科的发展。1795年HALLO-WELL首次作了血管裂伤修补术。在美国,1897年芝加哥西北大学第一个作了这种手术。1912年ALEXIs C... 详细信息

一、血管外科发展史:早在1522年AMDROIsE PARE就作了动脉瘤结扎术。1628年WILLIAM HARVEY发现血液循环推动了血管外科的发展。1795年HALLO-WELL首次作了血管裂伤修补术。在美国,1897年芝加哥西北大学第一个作了这种手术。1912年ALEXIs CARREL与***也在芝加哥作了动脉端一端吻合术的实验研究,Carrel的贡献后来获得了诺贝尔奖金。1940年加拿大人GORDON GORDONMURRAY提练出肝素,并用到临床,为血管外

关键词：血管外科转流术大隐静脉股深动脉

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

无创性血管检查技术

心肺血管病杂志 1985年第1期 6-7页

作者： james s.t.yao 吴庆华

无创性血管检查技术是诊断血管疾病的重要方法之一。应用它对诊断急性动脉阻塞、动脉瘤、急性下肢深静脉血栓形成、慢性下肢静脉循环障碍等疾病有较重要的意义。应用多普勒(Doppler)检查仪:不仅可以测量血压,也可测得血流声并将声音变... 详细信息

无创性血管检查技术是诊断血管疾病的重要方法之一。应用它对诊断急性动脉阻塞、动脉瘤、急性下肢深静脉血栓形成、慢性下肢静脉循环障碍等疾病有较重要的意义。应用多普勒(Doppler)检查仪:不仅可以测量血压,也可测得血流声并将声音变成电流描绘成为曲线。在正常情况下,可听到收缩期加速及减速的声音,舒张期下坡声及反跳声这三个声音。通过声音曲线,可分析血管是否正常,或在其近端是否有阻塞和狭窄。动脉阻塞的反向期消失,下降曲线速度减慢,严重阻塞时曲线则变成了直线。静脉曲线较动脉曲线频

关键词：血管检查多普勒容积曲线颈动脉血流下肢血压静脉血栓形成无创性静脉血流

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

股胫动脉转流血管移植

心肺血管病杂志 1985年第1期 8-9页

作者： james s.t.yao 吴庆华

下肢供血不足的转流手术,既往作股(?)动脉转流,近十年来采用股动脉—胫前动脉腓动脉的大隐静脉原位转流术,若静脉长度不够,也可采用大隐静脉加人造血管的复合系列吻合。这类手术的适应症是:(一)肢体有缺血坏死威胁时,为有效地保存肢体,... 详细信息

下肢供血不足的转流手术,既往作股(?)动脉转流,近十年来采用股动脉—胫前动脉腓动脉的大隐静脉原位转流术,若静脉长度不够,也可采用大隐静脉加人造血管的复合系列吻合。这类手术的适应症是:(一)肢体有缺血坏死威胁时,为有效地保存肢体,可作此类转流术。(二)先天性肢体血管畸型,肢体供血不足。

关键词：转流术手术肢体股浅动脉远端动脉人造血管假体

Epigenetic silencing of BEND4,a novel DNA damage repair gene,is a synthetic lethal marker for AtM inhibitor in pancreatic cancer

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Medicine 2024年第4期18卷 721-734页

作者： Yuanxin yao Honghui Lv Meiying Zhang Yuan Li james G.Herman Malcolm V.Brock Aiai Gao Qian Wang Francois Fuks Lirong Zhang Mingzhou Guo Department of Gastroenterology and Hepatology the First Medical CenterChinese PLA General HospitalBeijing100853China Department of Pharmacology School of Basic Medical SciencesZhengzhou UniversityZhengzhou450001China Henan Institute of Advanced technology Zhengzhou UniversityZhengzhou450001China UPMC Hillman Cancer Center University of Pittsburgh Medical CenterPittsburghPA15213USA Department of surgery School of MedicineJohns Hopkins School of MedicineBaltimoreMD21287USA Laboratory of Cancer Epigenetics Faculty of MedicineULB-Cancer Research Center(U-CRC)Universite Libre de Bruxelles(ULB)Brussels1070Belgium National Key Laboratory of Kidney Diseases the First Medical CenterChinese PLA General HospitalBeijing100853China

synthetic lethality is a novel model for cancer *** understand the function and mechanism of BEN domain-containing protein 4(BEND4)in pancreatic cancer,eight cell lines and a total of 492 cases of pancreatic neoplasia samples were included in this ***-specific polymerase chain reaction,CRIsPR/Cas9,immunoprecipitation assay,comet assay,and xenograft mouse model were ***4 is a new member of the BEN domain *** expression of BEND4 is regulated by promoter region *** is methylated in 58.1%(176/303)of pancreatic ductal adenocarcinoma(PDAC),33.3%(14/42)of intraductal papillary mucinous neoplasm,31.0%(13/42)of pancreatic neuroendocrine tumor,14.3%(3/21)of mucinous cystic neoplasm,4.3%(2/47)of solid pseudopapillary neoplasm,and 2.7%(1/37)of serous cystic ***4 methylation is significantly associated with late-onset PDAC(>50 years,Ptumor differentiation(Pthylation of BEND4 is an independent poor prognostic marker(Ps tumor-suppressive roles in vitro and in ***,BEND4 involves non-homologous end joining signaling by interacting with Ku80 and promotes DNA damage *** of BEND4 increased the sensitivity of PDAC cells to AtM ***,the present study revealed an uncharacterized tumor suppressor BEND4 and indicated that methylation of BEND4 may serve as a potential synthetic lethal marker for AtM inhibitor in PDAC treatment.

关键词： BEND4 DNA methylation synthetic lethality NHEJ pathway

Ranking environmental and edaphic attributes driving soil microbial community structure and activity with special attention to spatial and temporal scales

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

mLife 2024年第1期3卷 21-41页

作者： Vadakattu V.s.R.Gupta james M.tiedje CsIRO Agriculture&Food UrrbraeSouth AustraliaAustralia Centre for Microbial Ecology Michigan State UniversityEast LansingMichiganUSA

the incredibly complex soil microbial communities at small scales make their analysis and identification of reasons for the observed structures *** community structure is mainly a result of the inoculum(dispersal),the selective advantages of those organisms under the habitat-based environmental attributes,and the ability of those colonizers to sustain themselves over *** soil is protective,and its microbial inhabitants have long adapted to varied soil conditions,significant portions of the soil microbial community structure are likely ***,a substantial portion of the community will not correlate to often measured soil *** suggest that the drivers be ranked on the basis of their importance to the fundamental needs of the microbes:(i)those that supply energy,i.e.,organic carbon and electron acceptors;(i)environmental effectors or stressors,i.e.,pH,salt,drought,and toxic chemicals;(ii)macro-organism associations,i.e.,plants and their seasonality,animals and their fecal matter,and soil fauna;and(iv)nutrients,in order,N,P,and probably of lesser importance,other micronutrients,and *** relevance of drivers also varies with spatial and time scales,for example,aggregate to field to regional,and persistent to dynamic populations to transcripts,and with the extent of phylogenetic difference,hence phenotypic differences in organismal *** present a summary matrix to provide guidance on which drivers are important for particular studies,with special emphasis on a wide range of spatial and temporal scales,and illustrate this with genomic and population(rRNA gene)data from selected studies.

关键词： abundance community structure diversity functional microbiome microorganisms

time-Aware LstM Neural Networks for Dynamic Personalized Recommendation on Business Intelligence

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

tsinghua science and technology 2024年第1期29卷 185-196页

作者： Xuan Yang james A.Esquivel Graduate school Angeles University FoundationAngeles City 2009Philippines shandong Provincial University Laboratory for Protected Horticulture Weifang University of Science and TechnologyWeifang 262700China

Personalized recommendation plays a critical role in providing decision-making support for product and service analysis in the field of business ***,deep neural network-based sequential recommendation models gained considerable ***,existing approaches pay litle attention to users'dynamically evolving interests,which are influenced by product attributes,especially product *** overcome these challenges,we propose a dynamic personalized recommendation model:***,we first embed product information and attribute information into a unified data ***,we exploit long short-term memory(LstM)networks to characterize sequential behavior over multiple time periods and seize evolving interests by hierarchical LstM ***,similarity values between users are measured through pairwise interest features,and personalized recommendation lists are generated.A series of experiments reveal the superiority of the proposed method compared withotheradvanced methods.

关键词： personalized recommendations evolving interests embedding LstM networks

Management of male obesity-related secondary hypogonadism:A clinical update

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Experimental Medicine 2024年第2期14卷 11-28页

作者： Mohan t shenoy sunetra Mondal Cornelius james Fernandez Joseph M Pappachan Department of Endocrinology Sree Gokulam Medical Collegeand Research FoundationTrivandrum 695607KeralaIndia Department of Endocrinology NRS Medical College and HospitalKolkata 700014West BengalIndia Department of Endocrinology&Metabolism Pilgrim HospitalUnited Lincolnshire Hospitals NHS TrustBoston PE219QSUnited Kingdom Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine&HealthThe University of ManchesterManchester M139PLUnited Kingdom

the global obesity pandemic has resulted in a rise in the prevalence of male obesity-related secondary hypogonadism(MOsH)with emerging evidence on the role of testosterone *** aim to provide an updated and practical approach towards its *** did a comprehensive literature search across MEDLINE(via PubMed),scopus,and Google scholar databases using the keywords“MOsH”OR“Obesity-related hypogonadism”OR“testosterone replacement therapy”OR“selective estrogen receptor modulator”OR“sERM”OR“Guidelines on male hypogonadism”as well as a manual search of references within the articles.A narrative review based on available evidence,recommendations and their practical implications was *** weight loss is the ideal therapeutic strategy for patients with MOsH,achievement of significant weight reduction is usually difficult with lifestyle changes alone in real-world ***,androgen administration is often necessary in the management of hypogonadism in patients with MOsH which also improves many other comorbidities related to ***,there is conflicting evidence for the appropriate use of testosterone replacement therapy(tRt),and it can also be associated with *** evidence-based review updates the available evidence including the very recently published results of the tRAVERsE trial and provides comprehensive clinical practice pearls for the management of patients with *** starting testosterone replacement in functional hypogonadism of obesity,it would be desirable to initiate lifestyle modification to ensure weight *** should be coupled with the management of other comorbidities related to obesity in MOsH *** the risks and benefits of tRt should be considered in every patient before and during longterm management.

关键词： Male obesity-related secondary hypogonadism Androgen therapy testosterone replacement therapy Obesity Cardiovascular benefits

Probing turbulence in galaxies with fast radio burst scintillation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

science China(Physics,Mechanics & Astronomy) 2024年第1期67卷 177-178页

作者： james M.Cordes Department of Astronomy the Cornell Center for Astrophysics and Planetary ScienceCornell UniversityIthaca NY 14853USA

Interstellar scintillation(Iss)is a well-known phenomenon observed from pulsars in the Milky *** comprises intensity variations *** and frequency caused by constructive and destructive interference from multipath propagation,which is due to diffraction from fluctuations in electron density in the interstellar medium(IsM)on scales as small as~100 *** density fluctuations appear to be part of a turbulence process combined with discrete structures in electron density from other astrophysical processes;together these fluctuations extend to scales of pc or larger.

关键词： scales galaxies turbulence

维普期刊数据库

Deep Learning based Efficient Edge slicing for system Cost Minimization in Wireless Networks

在线全文

学校读者我要写书评

暂无评论

Journal of Communications and Information Networks 2024年第2期9卷 162-175页

作者： Wei Jiang Daquan Feng Liping Qian yao sun College of Information Engineering Zhejiang University of TechnologyHangzhou 310023China shenzhen Key Laboratory of Digital Creative technology Guangdong Province Engineering Laboratory for Digital Creative TechnologyCollege of Electronics and Information EngineeringShenzhen UniversityShenzhen 518060China james Watt school of Engineering University of GlasgowG128QQScotlandUK

It is widely recognized that the future wireless networks are able to efficiently slice heterogeneous resources to provide customized services for various use cases. However, it is challenging to meet the diverse requirements of ever-growing applications, especially the stringent requirements of numerous delay-sensitive and/or computation-intensive applications. to tackle this challenge, we should not only consider user admission control to cope with resource limitations, but also make resource management more intelligent and flexible to meet diverse service needs. taking advantages of mobile edge computing(MEC)and network slicing, in this paper, we propose deep edge slicing(DEs),to jointly optimize user admission control and resource scheduling with the aim of minimizing the system cost while guaranteeing multitudinous quality-of-service (Qos) requirements. specifically, we first apply a deep reinforcement learning approach to select the optimal set of access users with different service requests for maximizing resource *** a deep learning algorithm is employed to predict traffic data for allocating the communication and computing resources to different slices in advance. Finally, we realize the dynamic scheduling of heterogeneous resources by solving the optimization problem of minimizing the system cost. simulation results demonstrate that DEs can greatly reduce the system cost compared to other benchmarks.

关键词： deep learning mobile edge computing user admission control resource scheduling