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1例阴道疝的病例报道及文献回顾

世界核心医学期刊文摘（妇产科学分册） 2005年第11期1卷 6-6页

作者： Nasr A.O. Tormey s. Aziz M.A. Lane B. 朱国栋 Department of surgery Academic Center James Connolly Memorial Hospital Blanchardstown Dublin 15 Ireland

Objective: The purpose of this study was to discuss the treatment of a case of spontaneous intestinal herniation per vagina in a patient who had undergone previous transabdominal hysterectomy and to review the related literature. study design: A computer-based search of the English literature from January 1900 to October 2004 with the use of the terms vaginal herniation, vaginal evisceration, and vaginal trauma/injury was performed. Causes, presentation, and treatment were discussed and compared with a recent case that was treated locally in our hospital. Results: Vaginal evisceration was described in the literature as early as 1864; since then ses have been reported in the literature. It is more common in menopausal women with previous hysterectomy pelvic or vaginal surgery. Vaginal trauma, as in rough coitus, instrumentation, obstetric injury, is a recognized cause in premenopausal women. Conclusion: Vaginal evisceration is a rare, distressing emergency that requires aggressive resuscitation and urgent surgical intervention.

关键词：阴道疝文献回顾经腹子宫切除术肠疝粗暴性交绝经期妇女产伤急诊外科英文文献网上检索

small P values may not yield robust findings:an example using REsT-meta-PD

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science Bulletin 2021年第21期66卷 2148-2152,M0003页

作者： Xi-Ze Jia Na Zhao Hao-Ming Dong Jia-Wei sun Marek Barton Roxana Burciu Nicolas Carrière Antonio Cerasa Bo-Yu Chen Jun Chen stephen Coombes Luc Defebvre Christine Delmaire Kathy Dujardin Fabrizio Esposito Guo-Guang Fan Federica Di Nardo Yi-Xuan Feng Brett W.Fling saurabh Garg Moran Gilat Martin Gorges shu-Leong Ho Fay BHorak Xiao Hu Xiao-Fei Hu Biao Huang Pei-Yu Huang Ze-Juan Jia Christina Jones Jan Kassubek Lenka Krajcovicova Ajay Kurani Jing Li Qing Li Ai-Ping Liu Bo Liu Hu Liu Wei-Guo Liu Renaud Lopes Yu-Ting Lou Wei Luo Tara Madhyastha Ni-Ni Mao Grainne McAlonan Martin J.McKeown shirley Pang Andrea Quattrone Irena Rektorova Alessia sarica Hui-Fang shang james M.shine Priyank shukla Tomas slavicek Xiao-Peng song Gioacchino Tedeschi Alessandro Tessitore David Vaillancourt Jian Wang Jue Wang Z.Jane Wang Lu-Qing Wei Xia Wu Xiao-Jun Xu Lei Yan Jing Yang Wan-Qun Yang Nai-Lin Yao De-Long Zhang Jiu-Quan Zhang Min-Ming Zhang Yan-Ling Zhang Cai-Hong Zhou Chao-Gan Yan Xi-Nian Zuo Mark Hallett Tao Wu Yu-Feng Zang Center for Cognition and Brain Disorders the Affiliated HospitalHangzhou Normal UniversityHangzhou 310015China Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou 311121China National Basic science Data Center Beijing 100190China state Key Laboratory of Cognitive Neuroscience and Learning&McGovern Institute for Brain Research Beijing Normal UniversityBeijing 100875China school of Information and Electronics Technology Jiamusi UniversityJiamusi 154007China Neuroscience Program Central European Institute of TechnologyCEITECMasaryk UniversityBrno 62500Czech Republic Department of Applied Physiology and Kinesiology University of FloridaGainesville FL 32611USA Univ.Lille InsermCHU LilleU1172-LilNCog-Lille Neuroscience&CognitionLille F-59000France The Institute for Biomedical Research and Innovation National Research CouncilMangone CS 87050Italy Department of Radiology The First Affiliated Hospital of China Medical UniversityShenyang 110001China Department of Radiology Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China Department of Medicine Surgery and DentistryScuola Medica SalernitanaUniversity of SalernoFiscianoSA 132-84084Italy Department of Advanced Medical and surgery sciences University of Campania“Luigi Vanvitelli”Caserta 81100Italy Eye Center of the 2nd Affiliated Hospital Medical College of Zhejiang UniversityHangzhou 310020China Zhejiang Provincial Key Lab of Ophthalmology Hangzhou 310020China Department of Health and Exercise science Colorado State UniversityFort Collins CO 80523USA Pacific Parkinson’s Research Centre University of British ColumbiaVancouver BC V6E 2M6Canada Department of Medicine(Neurology)University of British Columbia Vancouver BC V6T 1B7Canada Brain and Mind Center The University of SydneySydney NSW 2006Australia Department of Neurology Ulm UniversityUlm 89081Germany Division of Neurology Department of MedicineQueen Mary HospitalUniversity of Hong KongHong Kong 999077China Department of

Thousands of resting state functional magnetic resonance imaging(Rs-f MRI)articles have been published on brain *** precise localization of abnormal brain activity,a voxel-level comparison is *** of the large number of voxels in the brain,multiple comparison correction(MCC)must be performed to reduce false positive rates,and a smaller P value(usually including either liberal or stringent MCC)is widely recommended[1].

关键词：帕金森病 precise correction

临床前X线散射对比扫描设备诊断小动物肺气肿

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国际医学放射学杂志 2014年第1期 66-66页

作者： A.Yaroshenko G.Felix B.Meinel A.Tapfer A.Velroyen s.Auweteret 丁芳芳 Department of Physics and Institute of Medical Engineering Technische Universitát München James-Franck-Strasse 1 85748 Garching Germany

目的验证临床前多光源锥形束扫描设备获得的X线联合分布与暗区信号可用来诊断离体小鼠肺气肿的推论。方法本研究得到动物保护委员会批准。采用栅格微型

关键词：肺气肿肺疾病临床前扫描设备

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变异组分析揭示番茄的育种历史

变异组分析揭示番茄的育种历史

中国园艺学会2014年学术年会

作者：林涛祝光涛张俊红徐向阳余庆辉郑峥张忠华伦尧尧李帅王孝宣黄泽军李君明张春芝王涛涛张余洋王傲雪张艳聪林魁李传友熊国胜薛勇彪 Andrea Mazzucato Mathilde Causse Zhangjun Fei james J.Giovannoni Roger T.Chetelat Dani Zamir Thomas stdler 李景富叶志彪杜永臣黄三文中国农业科学院蔬菜花卉研究所中国农业科学院农业基因组研究所华中农业大学东北农业大学新疆农业科学院园艺研究所北京师范大学中国科学院遗传发育研究所中国科学院北京基因组所 Department of Agriculture ForestsNatureand Energy(DAFNE)University of TusciaVia San Camillo de Lellis sncViterbo01100Italy Institut National de la Recherche Agronomique(INRA) Unite de Genetique et Amelioration des Fruits et LegumesDomaine Saint-MauriceMontfavet CedexF-84143France Boyce Thompson Institute for Plant Research U.S.Department of Agriculture(USDA) Robert W.Holley Centre for Agriculture and HealthIthacaCornell UniversityNew York14853USA C.M.Rick Tomato Genetics Resource Center Department of Plant SciencesUniversity of CaliforniaDavisCalifornia95616USA Robert H.smith of Plant sciences and Genetics Faculty of AgricultureThe Hebrew University of JerusalemRehovot76100Israel Plant Ecological Genetics Institute of Integrative BiologyETH ZurichZurich CH-8092Switzerland

植物基因组的变化能够充分体现人类对其驯化的历史过程。番茄是植物生物学和果实发育研究的重要模式物种之一,但是人类长期驯化对番茄基因组的影响仍是未知的。本研究通过对收集于世界各地360份番茄变异组的深入分析,鉴定了1160多万个s... 详细信息

植物基因组的变化能够充分体现人类对其驯化的历史过程。番茄是植物生物学和果实发育研究的重要模式物种之一,但是人类长期驯化对番茄基因组的影响仍是未知的。本研究通过对收集于世界各地360份番茄变异组的深入分析,鉴定了1160多万个sNPs变异位点,获得了该作物最全面的遗传变异图谱。基于番茄系统发生树的构建和群体结构分析,发现番茄群体分为3个亚群,即醋栗番茄、樱桃番茄和普通栽培番茄,提出了醋栗番茄经过樱桃番茄最终驯化为大果栽培番茄的两步驯化(Domestication and Improvement)理论。通过番茄遗传多样性分析,发现了5个单果质量QTL属于驯化阶段选择基因,1 3个单果质量QTL属于改良阶段选择基因。通过加工番茄和鲜食番茄的群体分化分析,发现了含有控制可溶性固形物和果实硬度的QTLs位点。利用全基因组关联分析(GWAs),鉴定了控制番茄果皮颜色的关键变异位点,为番茄品质育种提供了基因组数据支撑。现代育种中野生抗病基因被广泛应用到栽培番茄中,研究发现R基因的利用导致了大片段的外源渗入(例如:Tm-2,Chr.9,≈50 Mb),导致了严重的连锁累赘。全面分析了番茄的群体结构、遗传多样性、基因组进化历程和群体分化等最基本的生物学命题,提出栽培番茄是经过驯化和改良两个历史过程形成,为番茄生物学研究、基因克隆及遗传改良等提供理论指导。

关键词：番茄基因组驯化改良群体遗传

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基于辣椒基因组测序探究辣味在种群中的进化

辣椒杂志 2014年第2期12卷 40-50页

作者： seungill Kim Minkyu Park seon-In Yeom Yong-Min Kim Je Min Lee Hyun-Ah Lee Eunyoung seo Jaeyoung Choi Kyeongchae Cheong Ki-Tae Kim Kyongyong Jung Gir-Won Lee sang-Keun Oh Chungyun Bae saet-Byul Kim Hye-Young Lee shin-Young Kim Myung-shin Kim Byoung-Cheorl Kang Yeong Deuk Jo Hee-Bum Yang Hee-Jin Jeong Won-Hee Kang Jin-Kyung Kwon Chanseok shin Jae Yun Lim June Hyun Park Jin Hoe Huh June-sik Kim Byung-Dong Kim Oded Cohen Ilan Paran Mi Chung suh saet Buyl Lee Yeon-Ki Kim Younhee shin seung-Jae Noh Junhyung Park Young sam seo suk-Yoon Kwon Hyun A Kim Jeong Mee Park Hyun-Jin Kim sang-Bong Choi Paul W Bosland Gregory Reeves sung-Hwan Jo Bong-Woo Lee Hyung-Taeg Cho Hee-seung Choi Min-soo Lee Yeisoo Yu Yang Do Choi Beom-seok Park Allen van Deynze Hamid Ashrafi Theresa Hill Woo Taek Kim Hyun-sook Pai Hee Kyung Ahn Inhwa Yeam james J Giovannoni Jocelyn K C Rose Iben sφrensen sang-Jik Lee Ryan W Kim Ik-Young Choi Beom-soon Choi Jong-sung Lim Yong-Hwan Lee Doil Choi 刘峰张西露 Department of Plant science seoul National University Plant Genomics and Breeding Institute Seoul National University Department of Agricultural Biotechnology Seoul National University Department of Bioinformatics and Life science Soongsil University Vegetable Breeding Research Center Seoul National University Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael. Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael Department of Bioenergy science and Technology Chonnam National University Genomics Genetics Institute GreenGene BioTech Inc. Codes Division Insilicogen Inc. Ginseng Resources Research Laboratory Korea Ginseng Corporation Korea Research Institute of Bioscience and Biotechnology Division of Bioscience and Bioinformatics Myongji University Department of Plant and Environmental sciences New Mexico State University Chile Pepper Institute New Mexico State University seeders Inc. Department of Biological sciences Seoul National University Arizona Genomics Institute University of Arizona Agricultural Genome Center National Academy of Agricultural Science Rural Development Administration seed Biotechnology Center University of California Davis Davis California USA Department of systems Biology Yonsei University Department of Horticulture and Breeding Andong National University Us Department of Agriculture-Agricultural Research service Robert W. Holley Center Ithaca New York USA Boyce Thompson Institute for Plant Research Cornell University Ithaca New York USA Department of Plant Biology Cornell University Ithaca New York USA Biotechnology Institute Nongwoo Bio Yeoju Korea Genome Center University of California Davis Davis California USA National Instrumentation Center for Environmental Management Seoul National University Seoul Korea 湖南省蔬菜研究所

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表... 详细信息

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表明辣椒基因组大小约为番茄的4倍,辣椒基因组上存在大量gypsy转座子和花椰菜病毒家族元件的积累。结合转录组综合分析认为,辣椒素合成酶基因表达模式的改变及新功能化是导致辣椒素生物合成的原因,研究还发现辣椒与番茄在乙烯合成及果实成熟调控方面存在明显不同的分子模式。辣椒参考基因组的发布为辣椒营养品质和药用价值的改善提供了重要平台。

关键词：基因组测序辣椒素参考基因 Capsicum 转座子辣椒果实分子模式生物合成基因表达模式基因组大小

Global wood anatomical perspective on the onset of the Late Antique Little Ice Age (LALIA) in the mid-6th century CE

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science Bulletin 2022年第22期67卷 2336-2344页

作者： Ulf Büntgen Alan Crivellaro Dominique Arseneault Mike Baillie David Barclay Mauro Bernabei Jarno Bontadi Gretel Boswijk David Brown Duncan A.Christie Olga V.Churakova Edward R.Cook Rosanne D’Arrigo Nicole Davi Jan Esper Patrick Fonti Ciara Greaves Rashit M.Hantemirov Malcolm K.Hughes Alexander V.Kirdyanov Paul J.Krusic Carlos Le Quesne Fredrik C.Ljungqvist Michael Mc.Cormick Vladimir s.Myglan Kurt Nicolussi Clive Oppenheimer Jonathan Palmer Chun Qin Frederick Reinig Matthew salzer Markus stoffel Max Torbenson Mirek Trnka Ricardo Villalba Nick Wiesenberg Greg Wiles Bao Yang Alma Piermattei Department of Geography University of CambridgeCambridge CB23ENUK swiss Federal Research Institute(WsL) Birmensdorf 8903Switzerland Global Change Research Centre(CzechGlobe) Brno 60300Czech Republic Department of Geography Faculty of ScienceMasaryk UniversityBrno 61300Czech Republic Forest Biometrics Laboratory Faculty of Forestry“Stefan cel Mare”University of SuceavaSuceava 720229Romania Department of Biology Chemistry and GeographyUniversity of Quebec in RimouskiRimouski Qc.G5L 3A1Canada Archaeology&Palaeoecology School of Natural and Built EnvironmentQueen’s University BelfastBelfast BT71NNUK Department of Geology State University of New York at CortlandCortland NY 13045USA CNR-IBE Institute of BioEconomyNational Research CouncilTrento 38121Italy school of Environment The University of AucklandAuckland 1010New Zealand Laboratorio de Dendrocronología y Cambio Global Universidad Austral de ChileValdivia 509000Chile Center for Climate and Resilience Research(CR) Santiago 8370449Chile Cape Horn International Center(CHIC) Punta Arenas 6200000Chile Institute of Ecology and Geography Siberian Federal UniversityKrasnoyarsk 660041Russia Tree-Ring Laboratory Lamont-Doherty Earth ObservatoryColumbia UniversityPalisades NY 10964USA Department of Environmental science William Paterson UniversityWayne NJ 07470USA Department of Geography Johannes Gutenberg UniversityMainz 55099Germany Institute of Plant and Animal Ecology Ural BranchRussian Academy of SciencesYekaterinburg 620144Russia Ural Institute of Humanities Ural Federal UniversityYekaterinburg 620002Russia Laboratory of Tree-Ring Research University of ArizonaTucson AZ 85721USA sukachev Institute of Forest sB RAs Krasnoyarsk 660036Russia Department of Physical Geography Bolin Centre for Climate ResearchStockholm UniversityStockholm 10691Sweden Department of History Stockholm UniversityStockholm 10691Sweden Bolin Centre for Climate Research Stockholm UniversityStockholm 10691Sweden swedish Collegium for Advanced study

Linked to major volcanic eruptions around 536 and 540 CE, the onset of the Late Antique Little Ice Age has been described as the coldest period of the past two millennia. The exact timing and spatial extent of this exceptional cold phase are, however, still under debate because of the limited resolution and geographical distribution of the available proxy archives. Here, we use 106 wood anatomical thin sections from 23forest sites and 20 tree species in both hemispheres to search for cell-level fingerprints of ephemeral summer cooling between 530 and 550 CE. After cross-dating and double-staining, we identified 89Blue Rings(lack of cell wall lignification), nine Frost Rings(cell deformation and collapse), and 93Light Rings(reduced cell wall thickening) in the Northern Hemisphere. Our network reveals evidence for the strongest temperature depression between mid-July and early-August 536 CE across North America and Eurasia, whereas more localised cold spells occurred in the summers of 532, 540–43, and548 CE. The lack of anatomical signatures in the austral trees suggests limited incursion of stratospheric volcanic aerosol into the southern Hemisphere extra-tropics, that any forcing was mitigated by atmosphere-ocean dynamical responses and/or concentrated outside the growing season, or a combination of factors. Our findings demonstrate the advantage of wood anatomical investigations over traditional dendrochronological measurements, provide a benchmark for Earth system models, support cross-disciplinary studies into the entanglements of climate and history, and question the relevance of global climate averages.

关键词： Blue Rings Climate extremes Dendrochronology Late Antiquity Tree rings Volcanic eruptions

无病毒性肝炎硬化的肝细胞肝癌患者肝切除术后早期复发及转归

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肝胆外科杂志 2009年第4期17卷 319-319页

作者： N. de Liguori Carino s. Farid N. Khan A. Young G. Toogood R. Prasad P. Lodge 余孝俊（摘译）赵红川（审校） Hepatobiliary Unit University Hospital Aintree Liverpool UK st james University Hospital Department of Organ Transplatation st james University Hospital 不详