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Cerebral malaria: Epidemiological, Clinical and Prognosis Aspects in the Anesthesia-Resuscitation Department CHU Ignace Deen

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Open Journal of Emergency medicine 2023年第4期11卷 162-173页

作者： Abdoulaye touré Amadou Yalla Camara Almamy Bangoura m’mah Lamine Camara mohamed Soumah Saramba Nabe Department of Anesthesia-Resuscitation University Hospital of Ignace Deen of Conakry Conakry Guinea Department of medical and Surgical Emergency Donka University Hospital Conakry Guinea Department of Anesthesia-Resuscitation Donka University Hospital Conakry Guinea

Objective: To describe the epidemiological, clinical, paraclinical and prognostic aspects of cerebral malaria received in the anesthesia-resuscitation department. methodology: This was a prospective descriptive type study carried out in the anesthesia-resuscitation department over a period of three (03) months (June 01 to August 31, 2022). All patients admitted for cerebral malaria were included. Sociodemographic, clinical and prognostic parameters were studied. Results: We collected 25 cases out of 105 admitted patients (23.8%). The average age was 27.6 ± 9.5 years with extremes of 11 and 50 years. The sex ratio was 0.7 (m/F). Students and housewives were in the majority, i.e. 52% and 24%. Neurological disorders were found on admission in all patients, dominated by impaired consciousness at 100% followed by convulsion (60%), prostration (44%), confusion (36%) associated with deep coma in (68%). Gross hemoglobinuria was present in (84%) of cases. On the blood count, anemia was present in (70%) of the patients followed by thrombocytopenia in more than half of the cases (60%) and transfusion was necessary in 19 cases. P Falciparum malaria was found in all patients (100%), the average parasite density was 60342.8 ± 30425.6 trophozoites/μl with extremes of 9000 to 100000 trophozoites/μl. All our patients were treated with intravenous injectable artesunate. Transfusion was performed in 76% of our patients. Eighty percent of the patients had benefited from dialysis. High oxygen therapy was performed in (92%) of cases. The average duration of hospitalization was 5.74 ± days with extremes of 1 to 17 days. mortality was 48%. Conclusion: Cerebral malaria can take different clinical forms, the most important of which is cerebral involvement. Prompt initiation of appropriate resuscitation can reduce mortality.

关键词： Cerebral malaria mortality Resuscitation

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Isotherm and kinetic studies on the adsorption of humic acid molecular size fractions onto clay minerals

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Acta Geochimica 2019年第6期38卷 863-871页

作者： mohamed E.A.El-Sayed moustafa m.R.Khalaf james A.Rice Department of Chemistry and Biochemistry South Dakota State UniversityBrookingsSD 57007USA Soils Waterand Environmental Research InstituteAgriculture Research CenterEl-GizaEgypt Chemistry Department Faculty of ScienceMinia UniversityEl-Minia 61519Egypt

Humic acid(HA)can adsorb onto mineral surfaces,modifying the physicochemical properties of the ***,understanding the sorption behavior of HA onto mineral surfaces is of particular interest,since the fate and transport of many organic and inorganic contaminants are highly correlated to HA adsorbed onto clay *** to the extreme heterogeneity of HA,the extracted IHSS Leonardite humic acid(LHA)used in this work was fractionated using an ultrafiltration technique(UF)into different molecular size fractions(Fr1,>0.2μm;Fr2,0.2 pm-300,000 daltons;Fr3,300,000-50,000 daltons;Fr4,50,000-10,000 daltons;Fr5,10,000-1000 daltons).Equilibrium and the kinetics of LHA and fraction adsorption onto kaolinite and montmorillonite were *** results demonstrated that the maximum adsorption capacity of LHA,Frl,Fr2,Fr3,Fr4,and Fr5 was 5.99,13.69,10.29,7.02,5.9&and 5.09 on kaolinite while it was 8.29,22.62,13.17,8.91,8.62,and 5.69 on montmorillonite,*** adsorption equilibrium data showed that the adsorption behavior of LHA and its fractions could be described more practically by the Langmuir model than the Freundlich *** rate of humic acid fraction adsorption onto clays increased with decreasing molecular size fraction and increasing carboxylic group ***-first-and second-order models were used to assess the kinetic data and the rate *** results explained that LHA and its fractions adsorption on clay minerals conformed more to pseudosecondo rder.

关键词： Kaolinite montmorillonite Leonardite humic acid Humic acid fractions Kinetics Equilibrium

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The First Stegosaur (Dinosauria, Ornithischia) from the Upper Jurassic Shishugou Formation of Xinjiang, China

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Acta Geologica Sinica(English Edition) 2007年第3期81卷 351-356页

作者： JIA Chengkai Catherine A. FOSTER XU Xing james m. CLARK Institute of Vertebrate Paleontology Paleoanthropology Chinese Academy of Sciences Beijing 100044 China Research Institute of Exploration and Development Xinjiang Oilfield Company Karamay Xinjiang 834000 China Graduate University of the Chinese Academy of Sciences Beijing 100039 China Department of Anatomical Sciences Stony Brook University Stony Brook New York 11794 USA Department of Biological Sciences George Washington University Washington DC 20052 USA

A new stegosaur species, Jiangjunosaurusjunggarensis, gen. et sp. nov., is erected based on a specimen collected from the Upper Jurassic upper section of the Shishugou Formation in the Junggar Basin, Xinjiang, China. It represents the first stegosaur from the Jurassic of Xinjiang and increases the diversity of the dinosaur fauna in the Shishugou Formation. The new genus is characterized by symmetrical and proportionally wide tooth crowns, a sub-rectangular axial neural spine seen in lateral view, and large openings on the lateral surfaces of the cervical centra. A preliminary character analysis suggests that this new taxon is more derived than the middle Jurassic stegosaur Huayangosaurus but more primitive than most other known stegosaur species.

关键词： Dinosauria Stegosauria Upper Jurassic Shishugou Formation Xinjiang

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Understanding the impact of disease and vaccine mechanisms on the importance of optimal vaccine allocation

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Infectious Disease modelling 2023年第2期8卷 539-550页

作者： Isobel R.Abell james m.mcCaw Christopher m.Baker School of mathematics and Statistics The University of MelbourneMelbourneAustralia melbourne Centre for Data Science The University of MelbourneMelbourneAustralia Centre for Epidemiology and Biostatistics Melbourne School of Population and Global HealthThe University of MelbourneMelbourneAustralia Peter Doherty Institute for Infection and Immunity The Royal Melbourne Hospital and the University of MelbourneMelbourneAustralia Centre of Excellence for Biosecurity Risk Analysis The University of MelbourneMelbourneAustralia

Vaccination is an important epidemic intervention ***,it is generally unclear how the outcomes of different vaccine strategies change depending on population characteristics,vaccine mechanisms and allocation *** this paper we develop a conceptual mathematical model to simulate strategies for pre-epidemic *** extend the SEIR model to incorporate a range of vaccine mechanisms and disease *** then compare the outcomes of optimal and suboptimal vaccination strategies for three public health objectives(total infections,total symptomatic infections and total deaths)using numerical *** comparison shows that the difference in outcomes between vaccinating optimally and suboptimally depends on vaccine mechanisms,disease characteristics,and objective *** modelling finds vaccines that impact transmission produce better outcomes as transmission is reduced for all *** vaccines that impact the likelihood of symptomatic disease or dying due to infection,the improvement in outcome as we decrease these variables is dependent on the strategy *** a principled model-based process,this work highlights the importance of designing effective vaccine allocation *** conclude that efficient allocation of resources can be just as crucial to the success of a vaccination strategy as the vaccine effectiveness and/or amount of vaccines available.

关键词： mathematical modelling Epidemiology

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Rising tide: The global surge of type 2 diabetes in children and adolescents demands action now

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World Journal of Diabetes 2024年第5期15卷 797-809页

作者： Joseph m Pappachan Cornelius james Fernandez Ambika P Ashraf Department of Endocrinology and metabolism Lancashire Teaching Hospitals NHS TrustPreston PR29HTUnited Kingdom Faculty of Science Manchester Metropolitan UniversityManchester M156BHUnited Kingdom Faculty of Biology Medicine&HealthThe University of ManchesterManchester M139PLUnited Kingdom Department of Endocrinology&metabolism Pilgrim HospitalUnited Lincolnshire Hospitals NHS TrustBoston PE219QSUnited Kingdom Division of Pediatric Endocrinology and Diabetes Department of PediatricsUniversity of Alabama at BirminghamBirminghamAL 35233United States

Childhood-onset obesity has emerged as a major public healthcare challenge across the globe,fueled by an obesogenic environment and influenced by both genetic and epigenetic *** has led to an exponential rise in the incidence of type 2 diabetes mellitus in children and *** looming wave of diabetes-related complications in early adulthood is anticipated to strain the healthcare budgets in most *** there is a collective global effort to curb the devastation caused by the situation,the impact is poised to be pro-found.A multifaceted research effort,governmental legislation,and effective social action are crucial in attaining this *** article delves into the current epidemiological landscape,explores evidence concerning potential risks and consequences,delves into the pathobiology of childhood obesity,and discusses the latest evidence-based management strategies for diabesity.

关键词： Childhood obesity Diabesity Type 2 diabetes mellitus Adolescence Cardiovascular disease Pharmacotherapy

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modified model of Crack Tip Stress Field Considering Dislocation Slip Accumulation and Crack Tip Blunting

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Chinese Journal of mechanical Engineering 2023年第2期36卷 327-340页

作者： Jian Li Bing Yang Shuancheng Wang m.N.james Shoune Xiao Tao Zhu Guangwu Yang State Key Laboratory of Traction Power Southwest Jiaotong UniversityChengdu 610031China School of Engineering Computing&MathematicsUniversity of PlymouthPlymouth PL48AAEngland Department of mechanical Engineering Nelson Mandela UniversityPort Elizabeth 6001South Africa

This study uses the digital image correlation technique to measure the crack tip displacement field at various crack lengths in U71mnG rail steel,and the interpolated continuous displacement field was obtained by fitting with a back propagation(BP)neural *** slip and stacking of dislocations affect crack initiation and growth,leading to changes in the crack tip field and the fatigue characteristics of crack *** Christopher-james-Patterson(CJP)model describes the elastic stress field around a growing fatigue crack that experiences plasticity-induced *** the present work,this model is modified by including the effect of the dislocation field on the plastic zone of the crack tip and hence on the elastic field by introducing a plastic flow factorρ,which represents the amount of blunting of the crack *** Levenberg-marquardt(L-m)nonlinear least squares method was used to solve for the stress intensity *** verify the accuracy of this modified CJP model,the theoretical and experimental plastic zone errors before and after modification were compared,and the variation trends of the stress intensity factors and the plastic flow factorρwere *** results show that the CJP model,with the introduction ofρ,exhibits a good blunting *** the low plasticity state,the modified model can accurately describe the experimental plastic zone,and the modified stress intensity factors are more accurate,which proves the effectiveness of dislocation *** plastic flow correction provides a more accurate crack tip field model and improves the CJP crack growth relationship.

关键词： Digital image correlation Back propagation neural network Plastic zone CJP model Dislocation field

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Land Use and Soil Texture Effects on Organic Carbon Change in Dryland Soils, Senegal

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Open Journal of Soil Science 2013年第6期3卷 253-262页

作者： Assize touré Emile Temgoua Claire Guenat Bo Elberling Centre de Suivi Ecologique (CSE) Dakar-Fann Sénégal Faculty of Agronomy and Agricultural Sciences University of Dschang Dschang Cameroon Institute of Geogra- phy Copenhagen Denmark. Swiss Federal Institute of Technology EPFL ENAC IIE ECOS Lausanne Switzerland

Soil organic carbon (SOC) losses due to poor soil management in dryland are now well documented. However, the influence of soil properties on organic carbon change is not well known. The groundnut plant (Arachis hypogaea L.), and the dominant crop system in the Senegal’s Soudanian zone, have been compared with semi-natural savanna. Leaves, stems and roots biomass were measured, and soil characteristics were analysed. The total leaves and stems biomass was 1.7 and 2.7 mg ha-1 dry matter in groundnut fields and savanna respectively. Total SOC stocks were low (8 to 20 mg C·ha-1 within upper 0.2 m depth, 20 to 64 mg C·ha-1 within upper 1 m depth) and were significantly lower (P δ13C values show that SOC quality is transformed from the savanna plants (C4/C3 mixed-pools) to C3-pools in groundnut cultivated zone, with the organic matter signature more preserved in the clayey soils. This study confirms that converting woodland to groundnut fields provokes texture transformation and SOC loss. The results call for the extreme necessity to regenerate the wooded zone or encourage practices that favour SOC restitution.

关键词： δ13C Dryland Land Use Soil Organic Carbon Soil Texture

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Experimental Investigation of the Stability of the Performance Characteristics of a Photovoltaic module in the Face of Environmental and meteorological Factors

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Open Journal of Applied Sciences 2024年第2期14卷 589-608页

作者： Adingra Paul Arsène Kouassi Siaka touré Diakaridja Traoré Laboratoire des Sciences de la matière de l’Environnement et de l’Energie Solaire (LASMES) Unité de Formation et de Recherche des Sciences des Structures de la Matière et Technologie (UFR-SSMT) Université Félix Houphou&#235t Boigny Abidjan C&#244te d’Ivoire

The explosive technological improvement of photovoltaic systems as well as the necessity of populations to come to less expensive energy sources, that have led to an implosion at the level of solar panel manufacturers. This causes a large flow of these equipments to developing countries where the need is high, without any quality control. That conducted an experimental investigation on the performance characteristics of a 250 wp monocrystalline silicon photovoltaic module in other to check the verification and quality control. most of these PV panels which often have missing informations are manufactured and tested in places that are inadequate for our environmental and meteorological conditions. Also, their influences on the stability of internal parameters were evaluated in order to optimize their performance. The results obtained at maximum illumination (1000 w/m2) confirmed those produced by the manufacturer. The analysis of these characteristics showed that the illumination and the temperature (meteorological factors) influenced at most the stability of the internal characteristics of the module in the sense that the maximum power increased very rapidly beyond 750 w/m2 but a degradation of performance was accentuated for a temperature of the solar cells exceeding 50°C. The degradation coefficients were evaluated at -0.0864 V/°C for the voltage and at -1.6248 w/°C for the power. The 10° inclination angle of the solar panel proved to be ideal for optimizing overall efficiency in practical situations.

关键词： Renewables Energies Instruments Internal Parameters of Photovoltaic Panel monocrystalline Photovoltaic Panel Solar Energy Production Energy Intermittence

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migmatite-like textures in anthracite:Further evidence for low-grade metamorphic melting and resolidification in high-rank coals

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Geoscience Frontiers 2021年第3期12卷 428-436页

作者： james C.Hower Susan m.Rimmer maria mastalerz Nicola J.Wagner University of Kentucky Center for Applied Energy Research 2540 Research Park DriveLexingtonKY 40511USA School of Earth Systems and Sustainability Southern Illinois University CarbondaleCarbondaleIL 62901USA Indiana Geological&Water Survey Indiana UniversityBloomingtonIN 47405USA Department of Geology University of JohannesburgJohannesburgSouth Africa

Previous studies demonstrated that melting,initiated by supercritical fluids in the 375-400℃range,occurred as part of anthracite metamorphism in the Appalachian *** on the known behavior of vitrinite at high temperatures and,to a lesser extent,at high pressures,it was determined that the duration of the heating,melting,and resolidification event was about 1 *** the current study,featureless vitrinite within banded maceral assemblages demonstratesthe intimate association of melted and resolidified vitrinite with anthracite-rank *** analogy with metamorphosed inorganic rocks,such associations represent diadysites and embrechites,i.e.,cross-cutting and layered migmatites,*** though the temperature of formation of the anthracite structures is several hundred℃lower than that seen in metamorphosed inorganic rocks,anthracites are metamorphic rocks and the nomenclature for metamorphic rocks may be appropriate for coal.

关键词： Igneous metamorphic texture Pennsylvania mesozoic basins South Africa

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Biliary endoscopy in the management of primary sclerosing cholangitis and its complications

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Liver Research 2019年第2期3卷 106-117页

作者： Brian m.Fung james H.Tabibian University of California Los Angeles-Olive View Internal medicine Residency Program SylmarCAUSA Division of Gastroenterology Department of MedicineOlive View-University of California Los Angeles Medical CenterSylmarCAUSA

Primary sclerosing cholangitis(PSC)is a chronic,idiopathic,cholestatic liver disease characterized by inflammation and fibrosis of the intrahepatic and/or extrahepatic bile *** can affect individuals of all age groups and gender,has no established pharmacotherapy,and is associated with a variety of neoplastic(***)and non-neoplastic(*** strictures)hepatobiliary *** these considerations,endoscopy plays a major role in the care of patients with *** this review,we discuss and provide updates regarding endoscopic considerations in the management of hepatobiliary manifestations and complications of *** evidence is limited,we suggest pragmatic approaches based on currently available data and expert opinion.

关键词： Primary sclerosing cholangitis(PSC) Biliary tract disease Balloon dilation Cholangioscopy Dominant stricture Cholangiocarcinoma(CCA) Endoscopic retrograde cholangiopancreatography(ERCP)

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