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大坝与安全 2016年第1期30卷 65-70页

作者： In-Soo Jung Jennifer Frazier Burcu Akinci Mario Berges Semiha Ergan james h.garrett Jr. Christopher J.Kelly 邱祥兴(译) 许传桂(校) 美国卡内基梅隆大学美国陆军工程师兵团不详

当工程师评估大坝的风险时,他们需要各种各样的信息,如仪器数据、事故的历史记录、之前的风险评估报告、施工记录、大坝几何形状、地理位置信息等。然而,这些信息大多记录在不同文件中,或者由机构、个人掌握。这种大坝相关历史数据的存... 详细信息

当工程师评估大坝的风险时,他们需要各种各样的信息,如仪器数据、事故的历史记录、之前的风险评估报告、施工记录、大坝几何形状、地理位置信息等。然而,这些信息大多记录在不同文件中,或者由机构、个人掌握。这种大坝相关历史数据的存储方式过于分散,无助于综合评估以及在存储数据中挖掘知识以及分析数据的有效可视化。如果没有综合的信息库,工程师很难有效地做出风险确定的决策。为改进风险确定决策制定过程,先进的信息建模、分析和可视化技术已成功应用在建筑和基础设施领域。笔者概述并评价了这些最佳实践应用在大坝风险评估中的适用性、优势和局限性。具体而言,笔者回顾了信息模型、数据标准、可视化系统和数据分析等领域的最佳实践,并探讨如何利用它们改进大坝风险评估。笔者提出的最佳实践可以使工程师在一个综合环境中审查和交换所有必要信息,有可能改进现有大坝风险管理过程。

关键词：大坝信息模型数据标准可视化系统数据分析

Imagery Enhancement and Interpretation for Remote Visual Inspection of Aging Civil Infrastructure

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Tsinghua Science and Technology 2008年第S1期13卷 375-380页

作者： Lucio Soibelman james h.garrett Department of Civil and Environmental Engineering Carnegie Mellon University

In this paper, we describe an image enhancement and interpretation methodology to enhance and recognize surface defects and critical patterns from remote imagery of sewer pipeline inspection. The objective is to provide inspectors and professionals with better tools to allow them to examine the imagery for condition assessment. We present initial results of a collaboration with a robotic company through a case study on computer-assisted processing and interpretation of sewer pipeline inspection imagery. In the mean time, the described enhancement and interpretation methodology can also be applied to sewer pipeline condition assessment in an offline mode, where this methodology can support professionals’ examination of acquired sewer condition imagery.

关键词： remote visual inspection infrastructure assessment image processing and analysis defects region of interest detection classification

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Biochemistry 2nd ed.

Silk-based nerve guidance conduits with macroscopic holes modulate the vascularization of regenerating rat sciatic nerve

丛书名：国外优秀生命科学教学用书

2002年

作者： (美)Reginald h.garrett

来源：畅想之星图书光盘版（南... 评论

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Neural Regeneration Research 2025年第6期20卷 1789-1800页

作者： Carina hromada Patrick heimel Markus Kerbl LászlóGál Sylvia Nürnberger Barbara Schaedl james Ferguson Nicole Swiadek Xavier Monforte Johannes C.heinzel Antal Nógrádi Andreas h.Teuschl-Woller David hercher Department Life Science Engineering University of Applied Sciences Technikum WienViennaAustria Austrian Cluster for Tissue Regeneration ViennaAustria Ludwig Boltzmann Institute for Traumatology The Research Center in Cooperation with AUVAViennaAustria University Clinic of Dentistry Medical University of ViennaViennaAustria Department of Plastic Reconstructive and Aesthetic SurgeryLandesklinikum Wiener Neustadt2700 Wiener NeustadtAustria Department of Anatomy Histology and EmbryologyAlbert Szent-Györgyi Medical SchoolUniversity of SzegedSzegedHungary Medical University of Vienna Department of Orthopedics and Trauma SurgeryDevision of Trauma SurgeryViennaAustria Department of hand- PlasticReconstructive and Burn SurgeryBG Unfallklinik TuebingenUniversity of TuebingenTuebingenGermany

Peripheral nerve injuries induce a severe motor and sensory deficit. Since the availability of autologous nerve transplants for nerve repair is very limited, alternative treatment strategies are sought, including the use of tubular nerve guidance conduits(tNGCs). however, the use of tNGCs results in poor functional recovery and central necrosis of the regenerating tissue, which limits their application to short nerve lesion defects(typically shorter than 3 cm). Given the importance of vascularization in nerve regeneration, we hypothesized that enabling the growth of blood vessels from the surrounding tissue into the regenerating nerve within the tNGC would help eliminate necrotic processes and lead to improved regeneration. In this study, we reported the application of macroscopic holes into the tubular walls of silk-based tNGCs and compared the various features of these improved silk^(+) tNGCs with the tubes without holes(silk^(–) tNGCs) and autologous nerve transplants in an 8-mm sciatic nerve defect in rats. Using a combination of micro-computed tomography and histological analyses, we were able to prove that the use of silk^(+) tNGCs induced the growth of blood vessels from the adjacent tissue to the intraluminal neovascular formation. A significantly higher number of blood vessels in the silk^(+) group was found compared with autologous nerve transplants and silk^(–), accompanied by improved axon regeneration at the distal coaptation point compared with the silk^(–) tNGCs at 7 weeks postoperatively. In the 15-mm(critical size) sciatic nerve defect model, we again observed a distinct ingrowth of blood vessels through the tubular walls of silk^(+) tNGCs, but without improved functional recovery at 12 weeks postoperatively. Our data proves that macroporous tNGCs increase the vascular supply of regenerating nerves and facilitate improved axonal regeneration in a short-defect model but not in a critical-size defect model. This study suggests that further optimizatio

关键词： axon regeneration blood vessel functional recovery macroporous nerve lesion peripheral nerve repair sciatic nerve silk-based nerve guidance conduit vascularization

The human acrosome reaction

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Asian Journal of Andrology 2000年第3期2卷 172-178页

作者： h.W.G.Baker D.Y.Liu C.garrett M.Martic Univerity of Melboume Department of Obstetrics and Gynaecology Reproductive Services Melbourne IVF and Royal Women's HospitalCarltonVictoria 3053Australia.

We developed tests of sperm-oocyte interaction:sperm-zona binding,zona-induced acrosome reaction,sperm-zona penetration and sperm-oolemma binding,using oocytes which failed to fertilise in clinical in vitro fertilization(IVF).Although oocyte defects contribute to failure of sperm oocyte interaction,rarely are all oocytes from one wom-an *** or zero fertilization in standard IVFwas usually caused by sperm *** sperm-zona pel-lucida binding was frequently associated with failure of standard IVF and obvious defects of sperm motility or *** size and shape of the acrosome is particularly important for sperm binding to the *** proportion ofacrosome intact sperm in the insemination medium was related to the IVF *** the acrosome reaction with acalcium ionophore reduced sperm-zona *** acrosome dispersal with an acrosin inhibitor prevented sperm-zona ***-zona penetration was even more highly related to IVF rates than was sperm-zona *** patients had low or zero fertilization rates with standard IVF but normal sperm by conventional tests and normalsperm-zona *** of their sperm underwent the acrosome reaction on the surface of the zona and none penetrat-ed the *** contrast,fertilization and pregnancy rates were high with intmcytoplasmic sperm *** call thiscondition defective zona pellucida induced acrosome *** of the nature of the abnormalities in the signaltmnsduction and effector pathways of the human zona pellucida induced acrosome reaction should result in simpler testsand treatments for the patients and also provide new leads for contraceptive development.

关键词： male infertility fertilization in vitro sperm-ovum interactions zona pellucida acrosome reaction

Emergency Logistics Management for hazardous Materials with Demand Uncertainty and Link Unavailability

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Journal of Systems Science and Systems Engineering 2023年第2期32卷 175-205页

作者： Ginger Y.Ke james h.Bookbinder Faculty of Business Administration Memorial University of NewfoundlandSt.John’sNewfoundland and LabradorA1B 3X5Canada Department of Management Sciences University of WaterlooWaterlooOntarioN2L 3G1Canada

Due to its harmful nature,any incident associated with hazardous material(hazmat)may cause tremendous impacts on the surrounding people and the *** on the incident involving this specific type of good,we develop a reliable and robust emergency logistics network that considers both demand uncertainty and possible unavailability of particular links.A time-based risk measure is carefully designed upon the traditional risk assessment to reflect the stakeholder’s sensitivity to risk over response *** disruption and uncertainty are modeled as two sets of scenarios which are integrated into a bi-objective robust model to evaluate the trade-offs between risk and *** effectiveness of the emergency response can be assured by expenditures that add extra capacities to certain links or establish additional facilities that aid recovery from *** apply our model and approach to a real-world network in Guangdong *** results reveal the necessity of embedding consideration of uncertainty and unreliability into emergency network design problems;outline the importance of hedging against unpredictability by system redundancies;and indicate the impact of stakeholder’s orientation towards cost and risk on the location,allocation,and routing decisions in hazmat emergency response.

关键词： Emergency response hazardous materials robust optimization link disruption emergency demand uncertainty

Roles of Financial Innovation and Information Technology:Lessons from US Sub-prime Mortgage Crisis and Its Implications for China

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Chinese Geographical Science 2012年第3期22卷 343-355页

作者： james h LENZER JR Simon Xiaobin ZhAO International Center for China Development Studies & Department of Geography Faculty of Social Sciencesthe University of Hong KongHong KongChina

The mortgage loan has evolved from a local lending instrument into a major global security and its role is unparallel to other financial instruments in the process of financial globalization. This paper explains how technology and financial innovation transformed the mortgage loan from a local security into a premier global security traded worldwide. It examines the fundamental flaws of this process and why it does not work in regards to mortgage lending and the re-securitization products that were created through financial innovation. The findings show that regulation was unable to keep pace with financial innovation, which created an environment where actors in the financial service sector were able to behave geographically irresponsibly by using information asymmetries to their advantage by par- ticipating in moral hazard activities and engaging in other immoral and unethical business practices that were centered around localized geography, which ultimately contributed to the global financial crisis. It also examines the roll of financial innovation in regard to the Lehman Brothers Mini-Bond in hung and its role as a driving force behind China＇s newly emerging shadow banking sector. It concludes with a policy recommendation and its implication for China＇s continued economic development.

关键词： shadow banking US sub-prime mortgage crisis financial tsunami global financial crisis wealth man- agement vehicle China asset bubble

Allergic dermatitis after knee arthroscopy with repeated exposure to Dermabond Prineo^(TM) in pediatric patients:Two case reports

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World Journal of Orthopedics 2021年第11期12卷 931-937页

作者： james Robinson Kevin P Smidt garrett houk Janay McKie R Shane Barton Patrick Massey Department of Orthopaedic Surgery Louisiana State UniversityShreveportLA 71103United States School of Medicine Louisiana State UniversityShreveportLA 71103United States Department of Orthopaedic Surgery Shriners Hospital for ChildrenShreveportLA 71103United States

BACKGROUND Allergic contact dermatitis(ACD)secondary to Dermabond Prineo^(TM) is rare,but *** our knowledge,there are no described reports of this ACD reaction within the pediatric population following arthroscopic *** SUMMARY We report two cases of pediatric ACD upon second exposure to Dermabond Prineo^(TM) after knee *** cases presented within two weeks of the inciting second *** cases resolved with differing described combinations of sterile cleaning,diphenhydramine,and antibiotic *** long-term sequelae were *** This case report elucidates the rare complication of allergic dermatitis secondary to Dermabond Prineo^(TM) repeat exposure use in pediatric arthroscopy.

关键词： Dermabond Prineo Arthroscopy Sports medicine Contact dermatitis Case report

Kartogenin induces cartilage-like tissue formation in tendon–bone junction

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Bone Research 2014年第1期2卷 61-70页

作者： Jianying Zhang james h-C Wang MechanoBiology Laboratory Departments of Orthopaedic Surgery Bioengineering Mechanical Engineering and Materials Science and Physical Medicine and Rehabilitation University of Pittsburgh

Tendon-bone junctions （TBJs） are frequently injured, especially in athletic settings. healing of TBJ injuries is slow and is often repaired with scar tissue formation that compromises normal function. This study explored the feasibility of using kartogenin （KGN）, a biocompound, to enhance the healing of injured TBJs. We first determined the effects of KGN on the proliferation and chondrogenic differentiation of rabbit bone marrow stromal cells （BMSCs） and patellar tendon stern/progenitor cells （PTSCs） in vitro. KGN enhanced cell proliferation in both cell types in a concentration-dependent manner and induced chondrogenic differentiation of stem cells, as demonstrated by high expression levels of chondrogenic markers aggrecan, collagen II and Sox-9. Besides, KGN induced the formation of cartilage-like tissues in cell cultures, as observed through the staining of abundant proteoglycans, collagen II and osteocalcin. When injected into intact rat patellar tendons in vivo, KGN induced cartilage-like tissue formation in the injected area. Similarly, when KGN was injected into experimentally injured rat Achilles TBJs, wound healing in the TBJs was enhanced, as evidenced by the formation of extensive cartilage-like tissues. These results suggest that KGN may be used as an effective cell-free clinical therapy to enhance the healing of injured TBJs.

关键词： bone junction BMSCs