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Bilayer self.assembly on a hydrophilic, deterministically nanopatterned surf.ce

Nano Research 2013年第11期6卷 784-794页

作者： Gregory S. Smith Seung-Yong Jung james f. browning Jong K. Keum Nickolay V. Lavrik Mussie G. Alemseghed C. Patrick Collier Biology and Sof. Matter Division Oak Ridge National Laboratory Oak Ridge TN 37831 USA Center f.r Nanophase Materials Sciences Oak Ridge National Laboratory Oak Ridge TN 37831 USA Chemical and Engineering Materials Division Oak Ridge National Laboratory Oak Ridge TN 37831 USA Department of.Chemical and Materials Engineering University of Cincinnati Cincinnati OH 45221-0012 USA

We present measurements of.the in situ, microscopic architecture of.a self. assembled bilayer at the interf.ce between a regularly nanopatterned surf.ce and an aqueous sub-phase using neutron ref.ectometry. The substrate is patterned with a rectangular array of.nanoscale holes. Because of.the high quality of.the pattern, using neutron ref.ectometry, we are able to map the surf.ce-normal density distribution of.the patterned silicon, the penetration of.water into the pattern, and the distribution of.a deposited f.lm inside and outside of.the etched holes. In this stud; 1,2-dilauroyl-sn-glycero-3-phosphocholine （DLPC） single bilayers were deposited on the hydrophilic patterned surf.ce. f.r bilayers deposited either by vesicle f.sion （Vf. or by the Langmuir-Schaef.r （L-S） technique, the most consistent model f.und to f.t the data shows that the lipids f.rm bilayer coatings on top of.the substrate as well as the bottoms of.the holes in an essentially conf.rmal f.shion. However, while there is a single bilayer on the unetched silicon surf.ce, the lipids coating the bottoms of.the holes f.rm a complex bimodal structure consistent with a rough surf.ce produced by the etching process. This study provides insight into f.lm transf.r both outside and inside regular nanopatterned f.atures.

关键词： thin f.lm nanopattern neutron ref.ectivity lipid self.assembly

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Design of.Poiseuille f.ow Controllers Using the Method of.Inequalities

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International Journal of.Automation and computing 2009年第1期6卷 14-21页

作者： John McKernan james f. Whidborne George Papadakis Department of.Mechanical Engineering King s College London Strand Department of.Aerospace Sciences Cranfield University

This paper investigates the use of.the method of.inequalities （MoI） to design output-f.edback compensators f.r the problem of.the control of.instabilities in a laminar plane Poiseuille f.ow. In common with many f.ows, the dynamics of.streamwise vortices in plane Poiseuille f.ow are very non-normal. Consequently, small perturbations grow rapidly with a large transient that may trigger nonlinearities and lead to turbulence even though such perturbations would, in a linear f.ow model, eventually decay. Such a system can be described as a conditionally linear system. The sensitivity is measured using the maximum transient energy growth, which is widely used in the f.uid dynamics community. The paper considers two approaches. In the f.rst approach, the MoI is used to design low-order proportional and proportional-integral （PI） controllers. In the second one, the MoI is combined with Mcf.rlane and Glover＇s H∞ loop-shaping design procedure in a mixed-optimization approach.

关键词： Transient energy growth transient behaviour f.ow control Poiseuille f.ow method of.inequalities (MoI) mixed opti-mization H∞-optimization.

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Phylogenetic reconstruction of.Chirita and allies (Gesneriaceae) with taxonomic treatments

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Journal of.Systematics and Evolution 2011年第1期49卷 50-64页

作者： james f. SMITH Department of.Biological Sciences Boise State University

Chirita D. Don, a large genus in the subf.mily Cyrtandroideae of.Gesneriaceae, has been the subject of.much debate whether it is a natural group or not. In addition, the highly heterogeneous Chirita has also been very problematic with regard to delimitation and subdivision. Here we used the nrDNA internal transcribed spacer and cpDNA trnL-f.f.r molecular phylogenetic analaysis, combined with morphological data. Our results suggest that Chirita is an artif.cial, polyphyletic genus. The most important character that def.nes Chirita, the dorso-ventrally oblique and bilamellar stigma, has evolved convergently in dif.erent clades of.diandrous Cyrtandroideae. Chirita sensu stricto only includes the species of.Chirita sect. Chirita, whereas Chirita sect. Microchirita is an independent clade located at the basal node of.the phylogenetic tree. Chirita sect. Liebigia is closely related to Didymocarpus with an entire stigma unlike other species of.Chirita. The species of.Chirita sect. Gibbosaccus, Chiritopsis, Primulina, and Wentsaiboea f.rm a monophyletic group that is sister to a strongly supported clade comprising f.ur monotypic genera Paralagarosolen, Calcareoboea, Petrocodon, and Tengia. We f.rther analyzed the morphological evolution of.Chirita and identif.ed a series of.morphological synapomorphies f.r the monophyletic groups revealed herein, and thereby provide a taxonomic treatment in this study.

关键词： Chirita D. Don morphological evolution phylogenetic reconstruction polyphyly taxonomic treatment.

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Guided Explorations of.the Mechanics of.Solids and Structures (Cambridge Aerospace Series)

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1000年

作者： james f. Doyle

来源：畅想之星图书光盘版（南... 评论

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The health benef.ts of.selenium in f.od animals:a review

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Journal of.Animal Science and Biotechnology 2022年第6期13卷 1623-1633页

作者： Brittany M.Pecoraro Diego f.Leal Alba f.ias-De-Diego Matthew browning Jack Odle Elisa Crisci College of.Veterinary Medicine Department of Population Health and PathobiologyNorth Carolina State UniversityRaleighNorth CarolinaUSA Laboratory of.Developmental Nutrition Department of Animal ScienceNorth Carolina State UniversityRaleighNorth CarolinaUSA

Selenium is an essential trace mineral important f.r the maintenance of.homeostasis in animals and *** evinces a strong antioxidant,anti-inf.ammatory and potential antimicrobial *** biological f.nction is primarily achieved by its presence in selenoproteins as a f.rm of.*** def.ciency may result in an array of.health disorders,af.ecting many organs and systems;to prevent this,dietary supplementation,mainly in the f.rms of.organic(i.e.,selenomethionine and selenocysteine)inorganic(i.e.,selenate and selenite)sources is *** pigs as well as other f.od animals,dietary selenium supplementation has been used f.r improving growth perf.rmance,immune f.nction,and meat quality.A substantial body of.knowledge demonstrates that dietary selenium supplementation is positively associated with overall animal health especially due to its immunomodulatory activity and protection f.om oxidative *** also possesses potential antiviral activity and this is achieved by protecting immune cells against oxidative damage and decreasing viral *** this review we endeavor to combine established and novel knowledge on the benef.cial ef.ects of.dietary selenium supplementation,its antioxidant and immunomodulatory actions,and the putative antimicrobial ef.ect ***,our review demonstrates the gaps in knowledge pertaining to the use of.selenium as an antiviral,underscoring the need f.r f.rther in vivo and in vitro studies,particularly in pigs.

关键词： Antimicrobial Antioxidant f.od animals Immunomodulation Pig Selenium

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Phase segregation mechanisms of.small molecule-polymer blends unraveled by varying polymer chain architecture

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SmartMat 2021年第3期2卷 367-377页

作者： Jihua Chen Sanjib Das Ming Shao Guoliang Li Huada Lian Jian Qin james f.browning Jong K.Keum David Uhrig Gong Gu Kai Xiao Center f.r Nanophase Materials Sciences Oak Ridge National LaboratoryOak RidgeTennesseeUSA Department of.Electrical Engineering and Computer Science University of TennesseeKnoxvilleTennesseeUSA Wuhan National Laboratory f.r Optoelectronics Huazhong University of Science and TechnologyWuhanChina Department of.Materials Science and Engineering University of TennesseeKnoxvilleTennesseeUSA Department of.Chemical Engineering Stanford UniversityStanfordCaliforniaUSA Neutron Scattering Division Oak Ridge National LaboratoryOak RidgeTennesseeUSA

As phase separation between the small-molecule semiconductor and the polymer binder is the key enabler of.blend-based organic f.eld-ef.ect transistors(Of.Ts)f.bricated by low-cost solution processing,it is crucial to understand the underlying phase separation mechanisms that determine the phase morphology,which signif.cantly impacts device *** the parameter space investigated in previous work,here we investigate the f.rmation of.blends by varying the branch architecture of.the polymer binder and by shortening the solvent dry time using ultrasonic spray *** phase morphologies of.the resulting blend f.lms have been thoroughly characterized with a variety of.techniques in three dimensions over multiple length scales,including Af.,energy-f.ltered transmission electron microscope,and neutron ref.ectivity,and have been correlated with electrical transport *** the results,we have inf.rred that the phase morphology is kinetically determined,limited by the inherent slow movement of.polymer *** kinetic picture,supported by molecular dynamics modeling,not only consistently explains our observations but also resolves inconsistencies in previous *** achieved mechanistic understanding will guide f.rther optimization of.blend-based organic electronics,such as Of.Ts and organic photovoltaics.

关键词： neutron ref.ectivity organic f.eld-ef.ect transistors phase separation polymer binders

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Counting and Randomly Generating <i>k</i>-Ary Trees

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Applied Mathematics 2021年第12期12卷 1210-1215页

作者： james f. Korsh Computer and Inf.rmation Science Department Temple University Philadelphia USA

k-ary trees are one of.the most basic data structures in Computer Science. A new method is presented to determine how many there are with n nodes. This method gives additional insight into their structure and provides... 详细信息

关键词： Combinatorial Problems k-Ary Trees Random Generation

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Interaction f.rces between sof. magnetic particles in unif.rm and non-unif.rm magnetic f.elds

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Acta Mechanica Sinica 2010年第6期26卷 921-929页

作者： Ayyoub Mehdizadeh james f.Klausner Nima Rahmatian Department of.Mechanical and Aerospace Engineering University of FloridaP.O.Box 116300GainesvilleFL 32611-6300USA

The inf.uence of.the magnetization of.a sof. magnetic sphere on the surrounding magnetic f.eld is measured and *** interaction f.rce between two sof. magnetic particles is directly measured using an ultra precision load sensor in unif.rm and non-unif.rm magnetic f.elds. The interaction f.rce largely f.llows an inverse f.urth power law as a f.nction of.separation distance between particle centers. At small distances,the ef.ect of.magnetization of.one particle on the magnetization of.its adjacent particle causes the attractive（repulsive） f.rce to be larger（smaller） than that predicted by the inverse f.urth power *** theoretical prediction based on a modif.ed dipole model,that takes into account the coupling ef.ect of.the magnetization among sof. magnetic particles,gives excellent agreement with the measured f.rce in a unif.rm magnetic *** interaction f.rce under a non-unif.rm applied magnetic f.eld can be reasonably predicted using the dipole-dipole interaction model when the local magnetic f.eld is used to determine the magnetization.

关键词： Magnetic f.rce Magnetic charge model Magnetic dipole model Sof. magnetic particle

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An international physical activity and public health research agenda to inf.rm coronavirus disease-2019 policies and practices

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Journal of.Sport and Health Science 2020年第4期9卷 328-334页

作者： james f.Sallis Deepti Adlakha Adewale Oyeyemi Deborah Salvo Department of.f.mily and Preventive Medicine University of California San DiegoLa JollaCA 92093USA Mary Mackillop Institute f.r Health Research Australian Catholic UniversityMelbourne 3000Australia School of.Natural and Built Environment Queen’s University BelfastBelfast BT95AGUK Department of.Physiotherapy College of Medical SciencesUniversity of MaiduguriMaiduguri 600243Nigeria Prevention Research Center Brown SchoolWashington University in St.LouisSt.LouisMO 63130USA

Physical activity(PA)has strong relevance f.r limiting the harms to human health and well-being due to the coronavirus disease-2019(COVID-19)pandemic.1 Active muscles produce chemicals that improve immune f.nctioning,which in turn reduces the extent of.inf.ctions,and decreases inf.ammation,and these are the main causes of.the lung damage f.om severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)*** is a powerf.l preventive and therapeutic intervention f.r the most common pre-existing chronic conditions that increase risk of.severe COVID-19 inf.ctions and mortality.

关键词： inf.ammation mortality lung

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Expanding the donor pool: Hepatitis C, hepatitis B and human immunodef.ciency virus-positive donors in liver transplantation

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World Journal of.Gastroenterology 2019年第47期25卷 6799-6812页

作者： james f.Crismale Jawad Ahmad Division of.Liver Diseases Icahn School of Medicine at Mount Sinai

Liver transplantation(LT)remains the best option f.r patients with end-stage liver disease but the demand f.r organs f.om deceased donors continues to outweigh the available *** advent of.highly ef.ective anti-viral treatments has reduced the number of.patients undergoing LT f.r hepatitis C(HCV)and hepatitis B(HBV)related liver disease and yet the number of.patients waiting f.r LT continues to increase,driven by an increase in the patients listed with a diagnosis of.cirrhosis due to non-alcoholic steatohepatitis and alcoholrelated liver *** addition,human immunodef.ciency virus(HIV)inf.ction,which was previously a contra-indication f.r LT,is no longer a f.tal disease due to the ef.ectiveness of.HIV therapy and patients with HIV and liver disease are now developing indications f.r *** rising demand f.r LT is projected to increase f.rther in the f.ture,thus driving the need to investigate potential means of.expanding the pool of.potential *** mechanism f.r doing so is utilizing organs f.om donors that previously would have been discarded or used only in exceptional circumstances such as HCV-positive,HBV-positive,and HIVpositive *** advent of.highly ef.ective anti-viral therapy has meant that these organs can now be used with excellent outcomes in HCV,HBV or HIV inf.cted recipients and in some cases uninf.cted recipients.

关键词： Hepatitis C Hepatitis B Human immunodef.ciency virus Liver transplantation

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